• Title/Summary/Keyword: (A)SF

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Structural Characteristics and Properties of Silk Fibroin/Polyurethane Blend Films

  • Um, In-Chul;Kweon, Hae-Yong;Chang mo Hwang;Min, Byung-Goo;Park, Young-Hwan
    • International Journal of Industrial Entomology and Biomaterials
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    • v.5 no.2
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    • pp.163-170
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    • 2002
  • In this paper, silk fibroin (SF)/polyurethane (PU) blend films were fabricated to develop a new biomaterial for biomedical applications. These blend films were prepared using formic acid as a cosolvent, and structural characteristics and properties of blend films were investigated. FTIR results suggested that there was no specific interaction between SF and PU, implying molecular immiscibility in SF/PU blend films. Furthermore, it was revealed by XRD method that the crystalline region of blend components was not perturbed by counterpart polymers. The degree of phase separation of SF/PU blend films was diminished by increasing PU content in blend. Especially, the blend with 70% content of PU showed no evidence of macro-phase separation in SEM observation. However, SF/PU blend (70/30) was revealed to be phase-separated in a lower dimension confirmed by DMTA measurement. TGA result showed that thermal decomposition temperature of blend film was slightly decreased compared to those of SF and PU polymer itself, Though mechanical properties of SF/PU blend films were not good enough due to the solvent, blood compatibility of PU can be enhanced markedly by mixing with SF for SF/PU blend film.

Antiproliferative effect of Schisandrae Fructus extract on PC-3 human prostate cancer cells (오미자(五味子) 추출물의 인간 전립선암 세포주 PC-3에 대한 성장 억제 효과)

  • Moon, Jung-Min;Seok, Ga-Hyeong;Cho, Su-In
    • The Korea Journal of Herbology
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    • v.27 no.4
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    • pp.17-23
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    • 2012
  • Objectives : Schisandrae Fructus (SF) has traditionally been used to balance level of body fluid and to strengthen kidney function. It has been reported that the SF extract has antioxidant, hepatoprotective, neuroprotective and anticancer effects. This study investigated an antiproliferative effect of SF extract on PC-3 human prostate cancer cells and analyzed active ingredients of SF extract qualitatively and quantitatively. Methods : We examined the antiproliferative effect of SF extract with MTT assay, DAPI staining and annexin-V/7-AAD double staining. The active ingredients of SF extract were identified by using HPTLC and HPLC/DAD system. Results : SF-chloroform fraction inhibited growth of PC-3 cells and changed the morphology of nucleus in a dose dependent manner. A dose-dependent apoptotic cell death was also measured by flow cytometry analysis. It was analyzed that SF-chloroform fraction contained more schizandrin than other fractions by using HPTLC and HPLC/DAD system. Conclusions : These results suggest that SF extract and schizandrin may be a potential chemotherapeutic agent for the control of PC-3 human prostate cancer cells.

Installation and Test Run of Comprehensive Analysis System for SF6 in Power Equipment

  • Lee, Jeong Eun;Kim, Kwang Sin;Kim, Ah Reum;Park, Seoksoon;Kim, Kyeongsook
    • KEPCO Journal on Electric Power and Energy
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    • v.3 no.1
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    • pp.41-47
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    • 2017
  • After $SF_6$, which is being used in power equipment as an insulating material, is classified as one of the 6 major greenhouse gases, the maintenance and the refinement of used $SF_6$ started to get attention. In regard to this, KEPCO Research Institute (KEPRI) is developing $SF_6$ recovery and refinement technology starting with establishing a comprehensive $SF_6$ analysis system. With the analysis system, qualitative and quantitative analyses of the purity and the impurities of $SF_6$ before and after recovery, and before and after refinement have been carried out. The analysis system is comprised of GC-DID (Gas Chromatograph -Discharge Ionization Detector) for trace impurities analysis, GC-TCD (Thermal Conductivity Detector) for analyses of $SF_6$ purity and major impurities concentration from several hundred ppm up to percent range, GC-MSD (Mass Selective Detector) for analyses of impurities not included in standard gas, FT-IR (Fourier Transform-Infrared) Spectrometer for analysis of HF and $SO_2$, and moisture analyzer for analysis of moisture below 100 ppm. With this analysis system, complete analysis method of $SF_6$ has been established. This analysis system is being used in the maintenance of power equipment and the development of $SF_6$ recovery and refinement technologies. In this paper, the analysis results of four samples - gas and liquid phase $SF_6$ samples from a $SF_6$ refinement system before and after refinement are presented.

Downregulation of Cyclin D1 by Sophorae Flos through Proteasomal Degradation in Human Colorectal Cancer Cells

  • Lee, Jin Wook;Park, Gwang Hun;Eo, Hyun Ji;Jeong, Jin Boo
    • Korean Journal of Plant Resources
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    • v.28 no.6
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    • pp.727-733
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    • 2015
  • Although Sophorae Flos (SF) has been reported to exert an anti-cancer activity, molecular targets and mechanisms associated with anti-cancer activity of SF have been unclear. Because cyclin D1 has been regarded as an important regulator in the cell proliferation, we focused cyclin D1 and investigated the effect of SF on the cyclin D1 regulation in light of elucidating the molecular mechanism for SF’s anti-cancer activity. The treatment of SF decreased cellular accumulation of cyclin D1 protein. However, SF did not change the level of cyclin D1 mRNA. Inhibition of proteasomal degradation by MG132 attenuated SF-mediated cyclin D1 downregulation and the half-life of cyclin D1 was decreased in the cells treated with SF. In addition, a point mutation of threonine-286 to alanine attenuated SF-mediated cyclin D1 downregulation. Inhibition of ERK1/2 by a selective inhibitor, PD98059 suppressed cyclin D1 downregulation by SF. From these results, we suggest that SF-mediated cyclin D1 downregulation may result from proteasomal degradation through its threonine-286 phosphorylation via ERK1/2. SF-induced proteasomal degradation of cyclin D1 might inhibit proliferation in human colorectal cancer cells. The current study provides information on molecular events for an anti-cancer activity of SF

A study on the Supporting Program for Integrated Rehabilitation of Deteriorated Public Housing Blocks : Focused on the HOPE SF in San Francisco (노후 공공주택단지의 통합적 재생을 위한 지원제도에 관한 연구 : 샌프란시스코시 HOPE SF 프로그램을 중심으로)

  • Yoon, Hye-Yeong;Yoo, Hae-Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2807-2817
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    • 2015
  • The purpose of this study is to draw out implications and directions for improvements on national public rental housing policy by examining SF's public rental housing policy and conditions for low income households, and analyzing 'multilateral considerations for residents and communities' and 'concrete case and policy for support' which are discovered in process of re-development of large-scale public housing revitalization. The results were as follows: First of all, HOPE SF ensures to involve resident as participant in entire project considering exist communities and resettlement of resident. Secondly, HOPE SF supported to enhance the lives of existing residents and their community through integrated support system. Thirdly, HOPE SF collaborated with various participants as partner of city's rehabilitation, thus, invite community opinion to build a sense of cohesion. And for last, HOPE SF tried to create a new financial model for sustainable and practicable rehabilitation.

Evaluating the Reliability of Short-Form Berg Balance Scales and Short-Form Postural Assessment Scales in Chronic Stroke Survivors

  • Seung-Heon An;Dae-Sung Park
    • Physical Therapy Rehabilitation Science
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    • v.13 no.2
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    • pp.143-151
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    • 2024
  • Objective: This study aims to assess the test-retest reproducibility of the Short Form Berg Balance Scale (SF-BBS) and the Short Form Postural Assessment Scale for Stroke (SF-PASS) among chronic stroke survivors, focusing on their reliability for consistent measurements over time. Design: A cross-sectional study design Methods: Thirty chronic stroke survivors participated in this study, undergoing evaluations with SF-BBS and SF-PASS scales at two different points, separated by a seven-day interval. The analysis focused on test-retest reliability, employing statistical measures such as the Intra-Class Coefficient (ICC2,1), Standard Error of Measurement (SEM), Minimal Detectable Change (MDC), and MDC%, the Bland-Altman plot to assess the limits of agreement and the extent of random measurement error. Results: The study found notable test-retest reproducibility for both SF-BBS and SF-PASS, with ICC values demonstrating strong reliability (0.932 to 0.941, with a confidence interval of 0.889 to 0.973). SEM values for SF-BBS and SF-PASS were reported as 1.34 and 0.61, respectively, indicating low measurement error. MDC values of 3.71 for SF-BBS and 1.69 for SF-PASS suggest that the scales have an acceptable level of sensitivity to change, with reliability metrics falling below 20% of the maximum possible score. Conclusions: The findings suggest that both SF-BBS and SF-PASS exhibit high intra-class correlation coefficients, indicating strong test-retest reliability. The SEM and MDC values further support the scales' reproducibility and reliability as tools for evaluating mobility and dynamic balance in chronic stroke survivors. Therefore, these scales are recommended for clinical use in this population, providing reliable measures for assessing progress in rehabilitation.

Study on the Multi-stage Hollow Fiber Membrane Modules for SF6 Gas Separation (불화가스 분리를 위한 중공사막 모듈의 다단 기체분리공정 연구)

  • Jeong, Su Jung;Lim, Joo Hwan;Koh, Hyung Chul;Ha, Seong Yong
    • Membrane Journal
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    • v.26 no.2
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    • pp.159-165
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    • 2016
  • Polyimide hollow fiber membrane modules were prepared in order to investigate the process of multi stage gas separation. The modules performance was carried out using 50/50 of $N_2/SF_6$ mixed gas. The membrane modules has been tested for measuring gas flow rate and concentration under various stage cut at 0.5 MPa. The membrane modules showed a high recovery ratio at the same stage cut as $N_2/SF_6$ selectivity increased. Two stage process was fulfilled for improving $SF_6$ recovery ratio and $SF_6$ concentration. Eventually, two stage process showed higher performance of $SF_6$ recovery ratio and concentration ($SF_6$ recovery ratio = 95%, $SF_6$ conc. = 98%).

Conceptual Design and Operation Results for SF6 Decomposition and Pollution Control System (SF6 분해 및 무해화 시스템의 개념 설계 및 운영 결과)

  • Joongwon, Lee;Miyeong, Kim;Jiho, Ahn;Younghwan, Byun
    • KEPCO Journal on Electric Power and Energy
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    • v.8 no.2
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    • pp.111-118
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    • 2022
  • SF6 is used as an insulating gas because of its excellent electrical insulation properties, non-toxicity, and non-inflammability. On the other hand, the global warming potential of SF6 is 23,900 times higher than that of CO2. The Korea electric power cooperation (KEPCO) is responsible for 80% of the domestic SF6 usage, and approximately 6,000 tons are currently charged in electrical and power facilities. KEPCO will gradually replace the insulating gas with SF6-free gas from 2023. SF6 decomposition facilities are required because more than 60 tons of SF6 will need to be disposed of annually from existing equipment. This study developed a novel decomposition and pollution control system that can process 60 tons of SF6 per year. This facility can decompose more than 97.7% of SF6, with the emissions of hazardous and toxic materials below the legal limit.

The geometry change of carbon nanofilaments by SF6 incorporation in a thermal chemical vapor deposition system

  • Kim, Sung-Hoon
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.21 no.3
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    • pp.119-123
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    • 2011
  • Carbon nanotilaments (CNFs) could be synthesized on nickel catalyst layer-deposited silicon oxide substrate using $C_2H_2$ and$H_2$ as source gases under thermal chemical vapor deposition system. By the incorporation of $SF_6$ as a cyclic modulation manner, the geometries of carbon coils-related materials, such as nano-sized coil and wave-like nano-sized coil could be observed on the substrate. The characteristics (formation density and morphology) of as-grown CNFs with or without $SF_6$ incorporation were investigated. Diameter size reduction for the individual CNFs-related shape and the enhancement of the formation density of CNFs-related material could be achieved by the incorporation of $SF_6$ as a cyclic modulation manner. The cause for these results was discussed in association with the slightly increased etching ability by $SF_6$ addition and the sulfur role in SF 6 for the geometry change.

Characteristics of lightning impulse corona discharges under non-uniform electric fields in $SF_6$ and $SF_6/N_2$ mixtures (불평등전장에서 $SF_6$$SF_6/N_2$ 혼합기체의 뇌임펄스 전압에 대한 코로나 방전특성)

  • Lee, B.H.;Oh, S.K.
    • Proceedings of the KIEE Conference
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    • 2004.11a
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    • pp.129-132
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    • 2004
  • This paper presents an experimental study on the prebreakdown characteristics in $SF_6/N_2$ mixtures under non-uniform electric fields when subjected to the positive and negative lightning impulse voltages. $SF_6/N_2$ mixtures have a merit of an environmental aspect and cost reduction, and safty aspects. In order to analyze the prebreakdown processes in $SF_6/N_2$ mixtures stressed by impulse voltages, prebreakdown current and light were observed by a shunt with high sensitivity and a photo-multiplier tube, respectively. Additionally, characteristics of luminous events in flashovers were discussed.

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