• Journal of Venture Innovation
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• v.5 no.3
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• pp.1-17
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• 2022

Entrepreneurs recognize that their passion was an important factor in driving successful entrepreneurship. However, they were often unaware of the impact that third-party passions related to startups have on them. Therefore, in this study, it was verified whether the accelerator incubation program had an effective effect on portfolios. At this time, I tried to do an empirical analysis focusing on how the third-party accelerator entrepreneur passion affects the entrepreneurial performance of portfolios. To this end, a survey was conducted on representatives of portfolios across the country who completed the accelerator incubation program, and empirical testing was conducted based on 330 valid ones. As a result of empirical analysis, it was confirmed that mentoring and networking among accelerator incubation programs had a positive (+) effect on entrepreneurial performance of portfolios. On the other hand, education and seed investment in the accelerator program did not significantly affect the entrepreneurial performance of portfolios. On the other hand, it was tested that accelerator entrepreneur passion significantly moderated both the incubation program elements (education, mentoring, network, seed investment) and the entrepreneurial performance of portfolios. The results of this study are meaningful in that they reveal that the passion of accelerator entrepreneurs is an important lynchpin of incubation programs and the key to success in startups. In addition, this study suggests that it is important for startups to go one step further from seed investment and properly identify the accelerator entrepreneur and his passion, the key man of accelerators.

• Journal of the Microelectronics and Packaging Society
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• v.30 no.4
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• pp.61-68
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• 2023

In this study, Sn-3.5Ag-15.0Fe composite solder was manufactured and applied to TLP bonding to change the entire joint into a Sn-Fe IMC(intermetallic compound), thereby applying it as a high-temperature solder. The FeSn₂ IMC formed during the bonding process has a high melting point of 513℃, so it can be stably applied to power modules for power semiconductors where the temperature rises up to 280℃ during use. As a result of applying ENIG surface treatment to both the chip and substrate, a multi-layer IMC structure of Ni₃Sn₄/FeSn₂/Ni₃Sn₄ was formed at the joint. During the shear test, the fracture path showed that cracks developed at the Ni₃Sn₄/FeSn₂ interface and then propagated into FeSn₂. After 2hours of the TLP joining process, a shear strength of over 30 MPa was obtained, and in particular, there was no decrease in strength at all even in a shear test at 200℃. The results of this study can be expected to lead to materials and processes that can be applied to power modules for electric vehicles, which are being actively researched recently.

• Journal of Ginseng Research
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• v.47 no.6
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• pp.726-734
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• 2023

Background: Skeletal muscles play a key role in physical activity and energy metabolism. The loss of skeletal muscle mass can cause problems related to metabolism and physical activity. Studies are being conducted to prevent such diseases by increasing the mass and regeneration capacity of muscles. Ginsenoside Rg5 has been reported to exhibit a broad range of pharmacological activities. However, studies on the effects of Rg5 on muscle differentiation and growth are scarce. Methods: To investigate the effects of Rg5 on myogenesis, C2C12 myoblasts were induced to differentiate with Rg5, followed by immunoblotting, immunostaining, and qRT-PCR for myogenic markers and promyogenic signaling (p38MAPK). Immunoprecipitation confirmed that Rg5 increased the interaction between MyoD and E2A via p38MAPK. To investigate the effects of Rg5 on prevention of muscle mass loss, C2C12 myotubes were treated with dexamethasone to induce muscle atrophy. Immunoblotting, immunostaining, and qRT-PCR were performed for myogenic markers, Akt/mTOR signaling for protein synthesis, and atrophy-related genes (Atrogin-1 and MuRF1). Results: Rg5 promoted C2C12 myoblast differentiation through phosphorylation of p38MAPK and MyoD/E2A heterodimerization. Furthermore, Rg5 stimulated C2C12 myotube hypertrophy via phosphorylation of Akt/mTOR. Phosphorylation of Akt induces FoxO3a phosphorylation, which reduces the expression of Atrogin-1 and MuRF1. Conclusion: This study provides an understanding of how Rg5 promotes myogenesis and hypertrophy and prevents dexamethasone-induced muscle atrophy. The study is the first, to the best of our knowledge, to show that Rg5 promotes muscle regeneration and to suggest that Rg5 can be used for therapeutic intervention of muscle weakness and atrophy, including cancer cachexia.

• The Journal of Internal Korean Medicine
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• v.44 no.5
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• pp.904-910
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• 2023

Objectives: The aim of this case report is to present the effects of Korean medicine treatment in a patient with left facial paraesthesia, temporomandibular joint (TMJ) pain, and post-traumatic neck pain induced by cerebral infarction. Methods: A 26-year-old male patient was treated with Cheongpa-Jeon H, acupuncture, pharmacopuncture (Shinbaro2), and Chuna Therapy for 24 days of hospitalization. Left facial paraesthesia, TMJ pain, and post-traumatic neck pain were assessed with a Numeric Rating Scale (NRS) and EuroQoL-5 Dimension (EQ-5D). Post-traumatic neck pain was assessed using the Neck Disability Index (NDI). Results: After 24 days of treatment, the patient's left facial paraesthesia and left arm tingling sensation were relieved from NRS 6 to NRS 2. Left TMJ pain was reduced from NRS 5 to NRS 2. The EQ-5D score increased from 0.138 to 0.73. The NDI score decreased from 71.11 to 37.78. Conclusion: These results show that left facial paraesthesia, TMJ pain, and post-traumatic neck pain can be relieved with Korean medicine treatment. However, further well-designed studies are required to confirm these findings.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.4
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• pp.243-249
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• 2023

This case study showed improvement both in pain and gait disturbance caused by SCH. KM can be a positive treatment for reducing pain or improving gait disturbance caused by SCH, and it can be considered a treatment option for SCH. Future studies with a larger number of cases and longer period of follow-up in SCH with gait disturbance and rigidity are needed.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.4
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• pp.258-267
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• 2023

Objectives: This study aimed to compare the utility of the Psychoeducational Profile-Revised (PEP-R), Korean Wechsler Preschool and Primary Scale of Intelligence, Fourth Edition (K-WPPSI-IV), and Vineland Adaptive Behavior Scale, Second Edition (VABS-II) for evaluating developmental disabilities (DD) in preschool children. Additionally, we examined the correlations between the PEP-R, K-WPPSI-IV, and VABS-II. Methods: A total of 164 children aged 37-84 months were assessed. Children's development was evaluated using the PEP-R, K-WPPSI-IV, VABS-II, Preschool Receptive-Expressive Language Scale, and Korean Childhood Autism Rating Scale, Second Edition. Results: Of the 164 children, 103 had typical development (TD) and 61 had DD. The mean of the PEP-R Developmental Quotient (DQ), K-WPPSI-IV Full-Scale Intelligence Quotient (FSIQ), and VABS-II Adaptive Behavior Composite (ABC) scores were significantly higher in the TD group than in the DD group (p<0.001). The estimated area under the curve of the PEP-R DQ, K-WPPSI-IV FSIQ, and VABS-II ABC scores was 0.953 (95% confidence interval [CI]=0.915-0.992), 0.955 (95% CI=0.914-0.996), and 0.961 (95% CI=0.932-0.991), respectively, which did not indicate a statistically significant difference. The PEP-R DQ scores were positively correlated with the K-WPPSI-IV FSIQ (r=0.90, p<0.001) and VABS-II ABC scores (r=0.84, p<0.001). A strong correlation was observed between the K-WPPSI-IV FSIQ and VABS-II ABC scores (r=0.89, p<0.001). Conclusion: This study found that the PEP-R, K-WPPSI-IV, and VABS-II effectively distinguished DD from TD in preschool children, and no significant differences in utility were observed between them.

• The Journal of KAIRB
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• v.5 no.2
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• pp.51-58
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• 2023

Purpose: To validate the effectiveness of obtaining consent education on errors in the consent process and to develop the education program for researchers. Methods: From February 2019 to February 2022, a 30-minute, 1:1 face-to-face consent education developed using the ADDIE model was conducted on 78 nurses as principal investigators. An informed consent audit tool, which includes 6 items developed by Asan Medical Center Human Research Protection Center, was used to analyze errors in obtaining informed consent process. Data analysis was performed using the SPSS ver. 25.0, and the Mann-Whitney U-test and χ²-test were utilized to verify the difference in errors between the experimental and control groups. Results: The participants consisted of 42 in the experimental group and 36 in the control group, with no statistically significant difference between the 2 groups. Both 2 groups showed the highest frequency of documentation errors, followed by format errors, errors related to a suitability of investigator, participant, or participant's legally acceptable representative, witness and confidentiality issues. After education, there was a significant decrease in both format errors (p=0.002) and documentation errors (p<0.001) in the experimental group. The proportion of participants without any errors in all items was higher in the experimental group (35.7%) compared to the control group (5.6%), and this difference was statistically significant (p=0.001). Conclusion: The obtaining consent education program was found to be effective in reducing informed consent errors. This study emphasizes the importance of education, suggesting the need for its expansion and accessibility, as well as the necessity for all researchers conducting clinical studies to receive the obtaining consent education.

• Journal of Korean Society of Rural Planning
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• v.30 no.1
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• pp.57-66
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• 2024

This study aimed to develop a precise vegetation cover classification model for small streams using the combination of drone remote sensing and support vector machine (SVM) techniques. The chosen study area was the Idong stream, nestled within Geosan-gun, Chunbuk, South Korea. The initial stage involved image acquisition through a fixed-wing drone named ebee. This drone carried two sensors: the S.O.D.A visible camera for capturing detailed visuals and the Sequoia+ multispectral sensor for gathering rich spectral data. The survey meticulously captured the stream's features on August 18, 2023. Leveraging the multispectral images, a range of vegetation indices were calculated. These included the widely used normalized difference vegetation index (NDVI), the soil-adjusted vegetation index (SAVI) that factors in soil background, and the normalized difference water index (NDWI) for identifying water bodies. The third stage saw the development of an SVM model based on the calculated vegetation indices. The RBF kernel was chosen as the SVM algorithm, and optimal values for the cost (C) and gamma hyperparameters were determined. The results are as follows: (a) High-Resolution Imaging: The drone-based image acquisition delivered results, providing high-resolution images (1 cm/pixel) of the Idong stream. These detailed visuals effectively captured the stream's morphology, including its width, variations in the streambed, and the intricate vegetation cover patterns adorning the stream banks and bed. (b) Vegetation Insights through Indices: The calculated vegetation indices revealed distinct spatial patterns in vegetation cover and moisture content. NDVI emerged as the strongest indicator of vegetation cover, while SAVI and NDWI provided insights into moisture variations. (c) Accurate Classification with SVM: The SVM model, fueled by the combination of NDVI, SAVI, and NDWI, achieved an outstanding accuracy of 0.903, which was calculated based on the confusion matrix. This performance translated to precise classification of vegetation, soil, and water within the stream area. The study's findings demonstrate the effectiveness of drone remote sensing and SVM techniques in developing accurate vegetation cover classification models for small streams. These models hold immense potential for various applications, including stream monitoring, informed management practices, and effective stream restoration efforts. By incorporating images and additional details about the specific drone and sensors technology, we can gain a deeper understanding of small streams and develop effective strategies for stream protection and management.

• Journal of The Korean Association For Science Education
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• v.29 no.5
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• pp.564-579
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• 2009

The purpose of this study was to examine the change in the classes of the beginning science teachers through a cooperative mentoring program that induces the practice of reflective thinking. Participants in this study included three mentor-teachers, two teachers in doctorate or masters courses, one university professor, and three mentee-teachers who had less than four years of teaching experience. We collected data such as video recordings of mentee-teachers' classes and transcription, lesson plans, recording of one-on-one mentoring and transcription, mentor's and mentee's journals, and RTOP class observation reports. RTOP was used for the class analysis, and the cognition and changes in mentee-teachers' classes were determined from their journal entries and one-on-one mentoring interview materials. According to mentee-teachers' recognition of changes in their classes during the mentoring program, they themselves recognized their teacher-centered teaching styles, misconception, and lack of content knowledge. Furthermore, there were changes in the mentee-teachers' classes through their reflective practice and improvement. Based on the result of this study, however, the teachers' reflection was not all accompanied with reflective practice even if the beginner science teachers made some partial changes in reflective practice by reflection. This means that it is hard to instill a reflective practice in mentee-teachers through mentoring in a short period. Therefore, we consider that more systematic and long-term mentoring is necessary for beginner science teachers.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.14 no.1
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• pp.22-40
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• 2009

Detailed bathymetry and magnetic survey data for NW Rota-1 and Esmeralda Bank obtained by R/V Onnuri of Korea Ocean Research & Development Institute in September 2007 were analyzed to investigate bathymetry and magnetic characteristics of the study area and to estimate the locations of possible hydrothermal vents. The shape of NW Rota-1 is corn type, and the depth of the summit is about 500 meter b.s.l. NW Rota-1 shows irregular topographic expression in the southeastern part. The shape of Esmeralda Bank is caldera type opened in the western part. The summit is very shallow, about 50 meter b.s.l. The western part of Esmeralda Bank is more steeper and topographic irregular than the eastern part, and have the valley made by erosion or collapse. The magnetic anomaly patterns of NW Rota-1 and Esmeralda Bank show low anomalies over the north and high anomalies over the south. The magnetic anomalies are steep over the summits and gently smooth over the deep bottom. The low magnetization zone occurs over the summit of NW Rota-1 and is surrounded by the high zones correlated with its crater. Two low magnetization zones are located in the summit and westside of Esmeralda Bank. The low magnetization zones of the summits of NW Rota-1 and Esmeralda Bank suggest the possible existence of hydrothermal vent.