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Effect of Nogjungtang (Korean Traditional Deer Decoction) on Growth, Feed Efficiency and Hematologic Index in Sprague-Dawley Rats (녹중탕이 흰쥐의 성장, 식이효율 및 혈액형상에 미치는 효과)

  • Sung, Ha-Guyu
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.8
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    • pp.1164-1168
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    • 2005
  • Korean traditional deer decoction (Nogjungtang), composed of oriental herbs and almost deer parts, has been used as an important resource for human health. For basic studying on Nogjungtang, this experiment was conducted to evaluate nutritional effects of Nogjungtang, and estimate its effect on growth, food efficiency, organ development and hematological indices in growing and adult Sprague-Dawley rats. The rats were divided into three groups as follows; control: non-supplementation, Notiungtang I: recommended dose, and Nogjungtang II: thrice recommended dose. Nogjungtang was composed of various general nutrients with up 93$\%$ moisture.Crude protein is the highest value as 22.78$ \%$, Mg is a major mineral as 0.48$\%$ compared to other minerals, and methionine and proline are higher by 1.31 and 1.67$\%$ than other amino acids based on dry matter, re-spectively. In both growing and adult rats, there were no significant difference in body weight gain and feed intake between the control and Nogjungtang groups. Also, organs weights (liver, heart, kidney and stomach) and hematological indices (WBC, RBC, Hb, Hct and Platelet) did not show statistically significant differences among the experimental groups. However, all of experimental rats were normal growth without hypertrophy or negative development of organs by Nogjungtang. Hematological indices maintained in normal value by thrice recommended dose of Nogjungtang. The average body weight of each treatment groups showed similar levels at end of experiment. In case of the feed efficiency ratio (feed intake/body gain), the growing rats showed 6.00, 5.81 and 5.99 and adult rats showed 9.03, 8.98 and 9.10 in control, Nogjungtang I and Nogjungtang II, respectively. In conclusion, although further investigation of Nogjungtang should be performed in the functions registered in many ancient literatures, Nogjungtang is physiologically safe and may have potential as candidate food for human health.

Comparison of Daytime Sleepiness between Normal Subjects and Patients with Sleep Disorders and Analysis of Its Clinical Implications (정상인과 수면장애 환자군 간의 주간졸림증 비교 및 임상적 의미 분석)

  • Lee, Jin-Sung;Kim, Seog-Ju;Choi, Jong-Bae;Jeong, Do-Un
    • Sleep Medicine and Psychophysiology
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    • v.9 no.2
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    • pp.106-114
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    • 2002
  • Objectives: Daytime sleepiness is a common symptom and is associated with sleep behavior, sleep deprivation, and night shift, etc. It is also one of the most important symptoms of sleep disorders like obstructive sleep apnea (OSA). According to our survey on Korean literature, a few studies have dealt with daytime sleepiness, and we have not been able to locate any study comparing normal subjects with polysomnography-proven sleep disorder patients regarding daytime sleepiness. We aimed at comparing daytime sleepiness among normal healthy daytime workers, medical students being expected to have daytime sleepiness due to chronic sleep deprivation, and patients having sleep disorders diagnosed with polysomnography. We also studied the association between subjective daytime sleepiness and objective polysomnographic findings in patients with sleep disorders. Methods: One hundred three hospital workers, 137 medical students, and patients with sleep disorders were studied. Sleep disorders included OSA, periodic limb movements in sleep (PLMS), insomnia, and narcolepsy. The degree of subjective sleepiness in each group was measured by the Korean version of Epworth sleepiness scale and compared. The relationship between polysomnographic findings reflecting severity of sleep disorder in each patient group and subjective sleepiness was analyzed. As for patients with narcolepsy, the relationship between the mean sleep latency and subjective sleepiness was studied. Results: There was a significant difference of ESS score (F=68.190, dF=5.752, p<0.001) among daytime workers, medical students, and sleep disorder patients. In OSA patient group, the degree of the sleepiness had no significant correlation either with mean O2 satuaration (p=0.062) or with RDI (p=0.807). In PLMS patient group, there was no correlation between periodic limb movement index (PLMI) and subjective sleepiness (p=0.761). In narcolepsy patient group, the subjective sleepiness had no correlation with mean sleep latency measured with MSLT (p=0.055). Conclusion: We found a significant difference of subjective sleepiness among daytime workers, medical students, and patients with sleep disorders. However, no consistent correlation was found between severity of subjective sleepiness and objective polysomnographic findings reflecting severity of each sleep disorder. This research confirms that the evaluation of subjective sleepiness is important clinically, but it cannot substitute the objective measures such as nocturnal polysomnography and MSLT.

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Correlations between quality indices and consumer acceptance in environment-friendly 'Campbell early' grapes (친환경 포도의 품질 인자와 소비자 기호도의 상관성 분석)

  • Lee, Da Uhm;Bae, Jeong Mi;Ku, Kyung Hyung;Choi, Jeong Hee
    • Food Science and Preservation
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    • v.23 no.7
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    • pp.1058-1064
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    • 2016
  • This study investigated the correlation between physicochemical (color, soluble solids content (SSC), pH, titratable acidity (TA), and firmness) and sensory (appearance, taste, odor, and texture) characteristics of environment-friendly 'Campbell early' grapes to identify quality indices. For analysis, samples of similar-sized grapes were collected from five orchards. The results showed that the physicochemical characteristics of CIE $L^*$, CIE $a^*/b^*$, SSC, pH, TA, and firmness and the sensorial characteristics of color intensity, freshness of stem, odor, sourness, sweetness, and elasticity were different among groups. Correlation analysis results showed that an increase in sweetness and firmness and a decrease in sourness were associated with an increase in overall acceptance. Sourness and sweetness were positively correlated with CIE $L^*$ (r=0.88) and firmness (r=0.95), individually. In the principal component analysis results, component F1 and F2 explained 44.35% and 33.77%, respectively, of the total variance (78.12%). F1 represented firmness, sweetness, elasticity, hardness, grape odor, color intensity, sweet odor, sourness, and damage degree. F2 represented CIE $L^*$, TA, CIE $a^*$, CIE $a^*/b^*$, SSC/TA, SSC, and peel thickness. The results showed that consumer acceptance of 'Campbell early' grapes can be determined by assessing physicochemical attributes of firmness, CIE $L^*$, TA, CIE $a^*$, CIE $a^*/b^*$, SSC/TA, and SSC and various sensorial attributes including sweetness, fruit elasticity, fruit hardness, grape odor, and color intensity.

Evaluation on the Purification Capacity of Pollutants in the Tidal Flat (갯벌의 오염물질 정화능력 평가)

  • YOU Sun-Jae;KIM Jong-Gu
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.4
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    • pp.409-415
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    • 1999
  • To evaluate the purification capacity of pollutants (COD, $PO_4^{3-}-p$, $NO_3^{-}-N$, Cu, Cd, Pb) in the three tidal flats, Eueunri, Gyewhado, Chunjangdae, the experiments were carried out with the batch reactor equipped with artifical tidal flats. Eueunri tidal flat was $98.8\%$ content of silt and clay and Chungjangdae was $97.84\%$ content of sand. The organic matters (I.L., $COD_{sed}$, POC) in Eueunri tidal flat were 2$\~$8 times higher than other tidal flats. The purification capacity of COD was 0.75 kg/ha/12 hr in Eueunri, 0.60 kg/ha/12 hr in Gyewhado and 0.55 kg/ha/12 hr in Chunjangdae. The mean purification capacity of COD in three tidal flats was 1.27 kg/ha/day. The calculated purification capacity of COD was 25.4 ton/day in the disappeared tidal flat areas (20,000 ha) of the Saemangeum reclamation. The purification capacity of phosphorus was 0.21 kg/ha/12 hr in Gyewhado, 0.39 kg/ha/12 hr in Eueunri and 0.22 kg/ha/12hr in Chunjangdae. The nitrate was 0.53, 0.74 and 0.43kg/ha/12hr, respectively. The purification capacity of heavy metals (Cu, Cd, Pb) were 88.9g/ha/12hr, 11.0g/ha/12hr, 1.7g/ha/12hr in Gyewhado, 89.1g/ha/12hr, 18.0g/ha/12hr, 2.6g/ha/12hr in Eueunri and 55.3g/ha/12hr, 18.0g/ha/12hr, 2.1g/ha/12hr in Chunjangdae, respectively. Accordingly, the purification capacity of pollutants in Eueunri tidal flat with high contents of organic matter were higher than other tidal flats. So, the purification capacity of pollutants were affected by physical and/or chemical characteristics of tidal flats.

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The Relationship Between the NF-${\kappa}B$ Activity and Anti-inflammatory Action of Surfactant in the Acute Lung Injury of Rats (백서의 급성폐손상에서 surfactant의 항염증작용과 호중구의 NK-${\kappa}B$ 활성과의 관계)

  • An, Chang-Hyeok;Cha, Young-Joo;Lee, Kyoung-Hee;Yoo, Chul-Gyu;Lee, Byoung-Jun;Jeong, Do-Young;Lee, Sang-Hoon;Shin, Jong-Wook;Kim, Jae-Yeol;Park, In-Won;Choi, Byoung-Whui
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.5
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    • pp.519-529
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    • 2002
  • Background : The therapeutic effects of surfactants on acute lung injury derive not only from their recruiting action on collapsed alveoli but also from their anti-inflammatory action in the alveolar sapce. This study evaluated the anti-inflammatory action of a surfactant in an acute lung injury model of rats by neutrophils were recollected from the BAL fluid and the NF-${\kappa}B$ activity of the neutrophilic nuclear protein was evaluated. Methods : Male Sprague-Dawley rats weighing approximately 300 gram were divided into 3 groups, which consisted of 6 rats respectively. In the control group, normal saline(3ml/kg) was instilled into the trachea twice with 30 minute interval. In two other groups, acute lung injury was induced by the intra-tracheal instillation of LPS(5mg/kg). Thirty minutes later, either a surfactant(ST group; 30mg/kg) or normal saline(NT group: 3ml/kg) was instilled via the trachea. Twenty-four hours after the LPS instillation, the BAL fluid was retrieved to measure the WBC count and cytokine(IL-$1{\beta}$ and IL-6) levels. The neutrophils were isolated from the BAL fluid and the nuclear protein was extracted to evaluate the NF-${\kappa}B$ activity using a eletrophoretic mobility shift assay(EMSA). Results : The WBC count of the BAL fluid of the ST group($3,221{\pm}1,914{\times}10^3/{\mu}l$) was higher than that of the control group($356{\pm}275{\times}10^3/{\mu}l$)(p<0.05) and lower than that of the NT group($5,561{\pm}1,757{\times}10^3/{\mu}l$)(p<0.05)). The BAL fluid level of IL-$1{\beta}$ from the NT group($2,064{\pm}1,082pg/ml$) was higher than those of the ST group($360{\pm}234pg/ml$)(p<0.05) and the control group(0pg/ml)p<0.05) and control group($49{\pm}62pg/ml$)(p<0.05). The NF-${\kappa}B$ activity of the neutrophilic nuclear protein in the ST group and NT group was similar. Conclusion : The surfactant, attenuates the alveolar inflammation in the acute lung injury of rats model. However, its anti-inflammatory action does no't appear to be mediated by the inhibition of NF-${\kappa}B$ activity.

Fermentation Characteristics of Juice Pomace Feed by Horse Feces Microbes (말분변 미생물을 이용한 주스박 사료의 발효 특성)

  • Hwang, Won-Uk;Kim, Gyeom-Heon;Niu, Kai-Min;Lim, Joung-Ho;Woo, Jae-Hoon;Chae, Hyun-Seok;Park, Nam-Geon;Kim, Soo-Ki
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.37 no.4
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    • pp.290-300
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    • 2017
  • In vitro fermentation was conducted to figure out alternative fiber sources for horse feed. For the development of value-added products as a horse feed resource, the pomaces from apple, carrot, grape, and citrus were fermented under solid-state conditions in the presence of 60% soybean meal with 40% of each fruit pomace at 60% of moisture content. Lactobacillus plantarum SK3873, Lactobacillus plantarum SK3893, Weissella cibaria SK3880, and Bacillus subtilis SK3889 were isolated from the fermented fruit pomace by inoculation of horse feces. For the growth of Bacillus subtilis, Saccharomyces cerevisiae, and Lactobacillus plantarum, they were inoculated in 3-step order at 0, 12, and 24 h, respectively. The fruit pomace was fermented for 48 h at $35^{\circ}C$. The pH of the apple, carrot, grape, citrus and all mixed pomaces decreased from 5.45~6.25 to 4.40~4.77. Microbial growth was maintained at $10^8{\sim}10^9cfu/g$. After 12 and 24 h incubation, dry matter of carrot pomace were highest at 54.84 and 56.66%, respectively (P<0.05) and that of grape pomace was lower than others during fermentation (P<0.05). Dry matter was generally reduced by about 20%. NDF decreased gradually or maintained after 24 h, indicating the fiber degradation. Ash content tended to decrease during fermentation. After 48 hours fermentation, Bacillus, yeast and Lactobacillus showed an excellent growth by using juice by-products. These results suggest that fermented juice pomace has a potential as horse feedstuff with probiotics to maintain beneficial microflora in horse gut.

3D Modeling of Automobile Part Using Pattern Scanner and Efficiency Analysis (패턴스캐너를 이용한 자동차부품의 3차원모델링 및 효용성분석)

  • Han Seung-Hee
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.24 no.1
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    • pp.1-8
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    • 2006
  • Effective three dimensional modeling becomes essential in a wide range of drawings, such as construction, machinery and design. In particular, it has been developed as the tool enabling reverse design. Three dimensional modeling requires rapidity, accuracy and tangibility. Data acquisition methods for modeling including contact type coordinate measurement machine, LASER scanner, pattern scanner and digital photogrammetry. In this study, we try to analyze modeling techniques as well as introduce three dimensional modeling using pattern scanner. In addition, this study conducts three dimensional modeling using OPTO-Top pattern scanner with distinguished accuracy and rapidity, and then compare efficiency with digital photogrammetry. And, this study attempts to form environment that enables to turn around models on web in three dimensional ways.

A Framework for OAM in OBS Networks (OBS 네트워크의 OAM 기본 체제)

  • Shin Jong-Dug
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.1B
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    • pp.41-51
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    • 2004
  • Operation and maintenance (OAM) in optical burst switching (OBS) networks has not yet been addressed even though OBS has been gaining research interest in recent years. In this paper, we defined five OBS functions such as Burst Termination (BT), Burst Transmission (BTX), Burst Switching (BSW), Routing and Switching Control (RSC), and Protection and Restoration (PAR). A functional model for OBS networks and an OAM architecture are designed to meet the operational requirements. We present the first framework to realize OAM in OBS networks, including OAM activities, OAM-capable OBS nodes such as ingress edge, core, and egress edge nodes, OAM information and communication models and protocols. A number of examples of possible network failures are pointed out and the corresponding reactions to these using the proposed OAM architecture are presented.

The Directory Service System for Efficient Shared-Object Access in Collaborative-Authoring (공동저작에서의 효율적인 공유객체 액세스를 위한 디렉토리 서비스 시스템)

  • 전재우;오삼권
    • Proceedings of the Korean Information Science Society Conference
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    • 1999.10b
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    • pp.233-235
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    • 1999
  • 공동저작 관리 시스템은 효율적인 공동저작을 위해 공유객체관리기능, 세션관리기능, 텔리포인팅(telepointing) 기능, 그리고 공동저작 인지(collaboration awareness) 기능들을 제공해야 한다. 이 중 공유객체관리기능은 저작자로 하여금 등록된 공유객체들을 편리하게 액세스 할 수 있도록 하고 저작에 필요한 공유객체들을 등록, 변경, 그리고 삭제할 수 있도록 함으로써 작업효율을 증대시킬 수 있는 핵심기능이다. 최근의 연구는 주로 등록된 공유객체의 변경 및 불필요한 정보전송으로 인한 작업지연, 그리고 공유객체 액세스 권한의 효율적인 관리를 위한 플로어 제어(floor control)에 그 초점을 맞추고 있으나 공유객체관리를 위한 기법이나 구조에 관한 연구는 미흡하다. 편리한 공동저작을 위해서는 분산환경의 특징상 가 저작자들의 시스템에 자연스럽게 분산되어 있는 공유객체들을 저작자나 공유객체들의 실제 위치에 상관없이 액세스할 수 있도록 하고, 저작자로 하여금 공유객체의 등록 시에 유일명 부여(unique naming)를 가능하게 하여 필요한 공유객체를 쉽게 검색할 수 있도록 해야 한다. 이를 위해 본 논문은 공유객체 디렉토리 서비스(shared-object directory service)를 제안한다. 공유객체 디렉토리 서비스는 일반 디렉토리(normal directory)와 세션 디렉토리(session directory)를 저작자에게 제공하여 공유객체의 등록시에 유일명 부여를 가능하게 하고 필요한 공유객체 검색을 용이하게 한다.

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Psychosomatic Medicine in Korean Medical Practice : Past, Present and Future (한국 임상진료에서 정신신체 의학의 과거와 현재 그리고 미래)

  • Seo, Jeong-Seok
    • Korean Journal of Psychosomatic Medicine
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    • v.20 no.1
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    • pp.18-21
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    • 2012
  • It has passed 20 years since the first conference of the Korean Psychosomatic Society(KPMS) had been held. Therefore, it seems that it is the appropriate time to evaluate the current status and to look back the history of the Korean psychosomatic medicine in three aspects, clinical treatment, education, and research, and to make a plan for the future. Of the three areas, the clinical practice of Korean psychosomatic medicine will be discussed. As the past, I reviewed the historical background and development of KPMS, and the proposals presented at the first conference of KPMS in 1992. As the present, I presented the short stories about the psychosomatic clinic in Japan, Germany, and USA, to compare it with the present status of Korean one. And finally I made careful proposals for the future of the Korean psychosomatic medicine.

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