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Development and Evaluation of the Resuscitation Protocol for Dyspneic Patients in the Emergency Medical Center (일개 응급의료센터의 소생실에 입실한 호흡곤란 환자를 위한 임상 프로토콜 개발 및 적용)

  • Shin, Sun Hwa;Kim, Ju Won;Lee, Ji Yeon;Choi, Min Jin;Choi, Hee Kang
    • Journal of Korean Clinical Nursing Research
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    • v.20 no.2
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    • pp.223-235
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    • 2014
  • Purpose: Resuscitation rooms in emergency department are places for time-critical tasks. This study aimed 1) to develop a resuscitation protocol for dyspneic patients and 2) to evaluate the effect of the resuscitation protocol for dyspneic patients in improving clinical performances. Methods: A panel of experts including emergency physicians and nurses developed a resuscitation protocol for dyspneic patients which included a list of critical interventions and time-limits. The resuscitation protocol was implemented in a emergency medical center for two months. Clinical performances of health care providers were compared by analyzing video-recorded clinical performances. Results: The resuscitation protocol consisted of four steps: Initial treatments within 5 minutes, main treatments within 15 minutes, diagnostic tests within 30 minutes, and disposition within 60 minutes. A total of 43 dyspneic patients (23 patients experimental group, 20 patients control group) were included for the analysis of the clinical performance change. Clinical performance rates were improved significantly from control group (66.71%) to experimental group (82.41%) after implementing the resuscitation protocol (Z=-3.09, p=.004). Conclusion: The resuscitation protocol developed for dyspneic patients improved clinical performance rates of health care providers. Further development of clinical protocols for other emergent cases at resuscitation rooms are strongly recommended.

Expression and Clinical Significance of Myeloid Derived Suppressor Cells in Chronic Hepatitis B Patients

  • Lu, Li-Rong;Liu, Jing;Xu, Zhen;Zhang, Geng-Lin;Li, De-Chang;Lin, Chao-Shuang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.10
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    • pp.4367-4372
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    • 2014
  • We here document discovery of expression profile of myeloid derived suppressor cells (MDSCs) in chronic hepatitis B (CHB) patients and changes in the course of disease. The study population was composed of 75 outpatient HBV cases and 15 healthy control cases. Peripheral blood samples were collected for separation of mononuclear cells. Levels of MDSCs labeled with Lin-DR-CD11b+CD33+ obtained from peripheral blood mononuclear cells (PBMC), were revealed to have significant differences between the CHB and other groups. They were 0.414% for health control cases and 0.226% for CHB cases (Z=-2.356, p=0.0189). It also observed that the group of HBeAg positive cases had significant difference in MDSCs/PBMC median ($X^2=11.877$, p=0.003), compared with group of HBeAg negative cases and the healthy control group. It suggested considerable MDSCs might be involved in HBeAg immune tolerance. In addition, negative correlations between MDSCs/PBMC and parameters of ALT, AST and TBil, while positive correlation between MDSCs/PBMC and ALB parameter were found. Multiple comparisons between the four phases and health control phase again, there was a statistically sifnificant difference ($X^2=17.198$, p=0.002). Taken together, these findings may provide a new immunotherapy strategy for reduced the expression levels of MDSCs in CHB patients, through induction of an autoimmune response to virus removal.

Nutrient Leaching from Leaf Litter of Cropland Agroforest Tree Species of Bangladesh

  • Hasanuzzaman, Md.;Hossain, Mahmood
    • Journal of Forest and Environmental Science
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    • v.30 no.2
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    • pp.208-217
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    • 2014
  • Leaf litter is the main and quick source of organic matter and nutrient to the soil compared to other parts of litter. This study focused on the nutrients (N, P and K) leaching from leaf litter of Melia azadirachta, Azadirachta indica, Eucalyptus camaldulensis, Swietenia macrophylla, Mangifera indica, Zizyphus jujuba, Litchi chinensis, Albizia saman, Artocarpus heterophyllus, Acacia auriculiformis, Dalbergia sissoo and Khaya anthotheca as the common cropland agroforest tree species of Bangladesh. About (9 to 35) % of initial mass was lost, while Electric Conductivity (EC) and TDS (Total Dissolved Solid) of leaching water increased to (573 to 3,247) ${\mu}S/cm$ and (401 to 2,307) mg/l respectively after 192 hours of leaching process. Mass loss (%) of leaf litter, EC and TDS of leaching water showed significant (ANOVA, p<0.05) curvilinear relationship with leaching time. Initial concentration of NH4, PO4 and K in leaching water was found to increase significantly (p<0.05) up to 48/72 hours and then remained almost constant at later stages (48/72 to 192 hours). Mass loss of leaves; EC, TDS, $NH_4$, $PO_4$ and K in leaching water was varied also significantly (ANOVA, p<0.05) among the studied tree species. All the tree species showed similar pattern of nutrients (K>N>P) release during the leaching process. The highest $NH_4$ (4,097 ppm) and potassium (8,904 ppm) concentration was found for M. azadirachta while the highest $PO_4$ (1,331 ppm) concentration was found for E. camaldulensis in the leaching water. Among the studied tree species, M. azadirachta, A. indica, D. sissoo, E. camaldulensis and Z. jujuba was selected as the best tree species with respect to nutrient leaching.

Crystal Structure of cis-(Malonato)[(4R,5R)-4,5-bis(Aminomethyl)-2-Isopropyl-1,3-Dioxolane]Platinum(II), A Potent Anticancer Agent

  • Cho, Sang-Woo;Yongkee Cho;Kim, Dai-Kee;Wanchul Shin
    • Korean Journal of Crystallography
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    • v.11 no.1
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    • pp.22-27
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    • 2000
  • The structure of cis-(malonato)[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane]platinum(II) with a potent anticancer activity has been determined by the X-ray crystallographic method. Crystal data are as follows: Pt(C/sub 11/H/sub 20/N₂O/sub 6/), M/sub 4/=471.38, monoclinic, P2₁, a=7.112(1), b=33.615(3), c=7.135(1)Å, β=116.80(1)°, V=1522.6(3)Å, and Z=4. The two independent molecules with very similar structures are approximately related by pseudo two-fold screw axis symmetry, which makes the monolinic cell look like the orthorhombic cell with one molecule in the asymmetric unit and space group C222₁. The crystal packing mode is similar to that of the analogue with the dimethyl substituents instead of the isopropyl group. The Pt atom is coordinate to two O and two N atoms in a square planar structure. The six-membered chelate ring in the leaving ligand assumes a conformation intermediate between the half chair and the boat forms. The seven-membered ring in the carrier ligand assumes a twist-chair conformation and the oxolane ring assumes an envelope conformation. Crystal packing consists of the extensive hydrogen-bonding network in the two-dimensional molecular layers and weak van der Waals interactions between these layers.

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Numerical Analysis of The Foundation Based on The Cap Model(I) (Cap Model을 이용한 기초식반의 수치해석(I) : 실내시험에 의한 Cap Model 의 Parameter 결정)

  • 박병기;정진섭
    • Geotechnical Engineering
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    • v.3 no.1
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    • pp.65-76
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    • 1987
  • This study has been carried out as a basic course for the analysis of foundation deformations based on the Cap model using the finite element methods. Material parameters should firstly be determined in order to use the Cap model for numerical solution. Associated with the fact described above, a method determining the soil parameters is suggested using algorithm for numerical ana])isis from raw truly triaxial compression laboratory test data of Pueblo.Colorado sand by Zaman, et at. (1982) More specifically, the change of soil parameters Is thoroughly examined by weighting the data obtained from CTC and RTE tests, respectively. The main results obtained are as follows; 1. The obtained values of parameters (E, V and 2) are same irrespective of data obtained from various kind of tests. 2. The values of the other parameters are dependent on data used. 3. The determination of parameters is little affected by the weighting factor.

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Discovery of Sub-pc Scale Plasma Torus in the Nearby Radio Galaxy 3C 84 with the KVN and VERA Array (KaVA)

  • Wajima, Kiyoaki;Kino, Motoki;Kawakatu, Nozomu
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.32.4-33
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    • 2016
  • 활동성은하핵(AGN)의 거대 블랙홀 주변에 존재하는 플라스마 디스크의 구조나 물리적인 상태를 관측으로 직접 찾는 것은 AGN 중심부분에서의 제트 형성, 방출과정이나 에너지 수송과정을 조사하기 위해 중요한다. 지금껏 주로 센치미터파장 영역의 다주파 VLBI 관측으로 우리은하에서 가까운 AGN 속에 존재하는 10 pc 정도의 플라스마 디스크가 발견되어 있다만, AGN의 활동성을 정하고 있는 1 pc 이하의 스케일에서의 디스크 구조를 직접 관측한 결과는 아직 없다. 우리는 2015년8월부터 KVN 및 KVN과 일본 VERA로 구성되는 한일공동 VLBI 관측망(KaVA)을 이용해서 전파 은하 3C 84(z = 0.0176, 1 mas = 0.36 pc)의 밀리미터파장 모니터링을 진행하고 있다. KVN과 KaVA를 이용하면 1 pc 이하의 스케일로 3C 84의 중심구조를 고감도에서 분해할 수 있다. 이번 발표에서는 KVN 및 KaVA로 거의 동시에 실시한 관측결과를 중심으로 보고한다. 관측은 2016년2월22일(KaVA 43 GHz) 및 23일(KVN 86 GHz)에 실시되었다. 양 주파수의 이미지에서 종래의 센치미터 ~ 밀리미터파장 VLBI관측으로도 검출되어 있는 중심핵(C1) 및 남쪽에 약 3 mas 떨어져서 위치하는 로브(C3) 성분 뿐만 아니라 C1으로부터 북쪽에 약 2.5 mas 떨어져서 위치하는 새로운 성분(N1)을 검출하였다. N1의 검출 수준은 43, 86 GHz 모두 $6{\sigma}$이며, 양 주파수 사이에서 광학적으로 두꺼운 스펙트럼을 가지고 있다. 과거의 관측으로 측정된 C3의 겉보기 속도는 빛의 속도의 약 23%이며, 남북 로브의 구조와 운동의 대칭을 가정하면 N1이 도플러 분사출 효과 때문에 어두워지고 있는 가능성은 낮다. 따라서 C3에 대응하는 북쪽 N1로브로부터의 복사가 블랙홀 주변의 플라스마 디스크로 인해 저주파수에서 강한 흡수를 받고 있는 결과고 생각된다.

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Phase-space Analysis in the Group and Cluster Environment: Time Since Infall and Tidal Mass Loss

  • Rhee, Jinsu;Smith, Rory;Choi, Hoseung;Yi, Sukyoung K.;Jaffe, Yara;Candlish, Graeme;Sanchez-Janssen, Ruben
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.45.2-45.2
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    • 2017
  • Using the latest cosmological hydrodynamic N-body simulations of groups and clusters, we study how location in phase-space coordinates at z = 0 can provide information on environmental effects acting in clusters. We confirm the results of previous authors showing that galaxies tend to follow a typical path in phase-space as they settle into the cluster potential. As such, different regions of phase-space can be associated with different times since first infalling into the cluster. However, in addition, we see a clear trend between total mass loss due to cluster tides and time since infall. Thus, we find location in phase-space provides information on both infall time and tidal mass loss. We find the predictive power of phase-space diagrams remains even when projected quantities are used (i.e.,line of sight velocities, and projected distances from the cluster). We provide figures that can be directly compared with observed samples of cluster galaxies and we also provide the data used to make them as supplementary data to encourage the use of phase-space diagrams as a tool to understand cluster environmental effects. We find that our results depend very weakly on galaxy mass or host mass, so the predictions in our phase-space diagrams can be applied to groups or clusters alike, or to galaxy populations from dwarfs up to giants.

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Study on the Statistical Turbulent Characteristics of $45^{\circ}$ Circular Cross Jet Flow ($45^{\circ}$ 圓形 衝突噴流의 統計學的 亂流特性 硏究)

  • 노병준;김장권
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.1
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    • pp.110-120
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    • 1986
  • 45.deg. corss jet flow, at the mixing of two jet flows, was experimentally studied. For this study, only the statistical turbulent characteristics and high order moments will be analysed by on-line computer system (hot-wire anemometer system, dynamic analyser and computer system, plotting and printing system). Since mean velocity distributions, intensities of turbulence, Reynolds stresses, correlation coefficients, and other general results were already studied and presented. One dimensional probability density distributions of u', v', and w' were analysed comparing with Gaussian curve, which showed skew and flat tendency according to the Y and Z directions. For the analysis of the joint flow of turublent components, the joint probability density distributions were examined. The fagures were drawn so as to be read joint probabilities, joint probability densities, fluctuating velocities u', v', and w'. For further detailed examination of the variations of skewness and flatness phenomena, iso-joint probability density contours obtained from the profiles of the joint probability density distributions were studied. According to the displacement of positions from the center of the mixing flow and the directions, the flatness and skewness factors were increased.

A Study on the Convective Heat Transfer in a Regenerative Ice Energy System by a Bundle of the Heat-pipes. (히이트파이프 다발을 이용한 냉축열시스템에서의 대류열전달에 관한 연구)

  • 권형정;김경석;김경근
    • Journal of Advanced Marine Engineering and Technology
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    • v.14 no.4
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    • pp.57-66
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    • 1990
  • In the design of an electric power plant, the capacity to meet the peak load demand is one of the important factors to be considered. This peak load usually occurs when the most of the cooling air conditioning systems are being operated during daytime in summer season, which inevitably entails the construction of an additional electric power plant. This study is aimed to carry out a basic experiment for the development of a cooling air conditioning system using the ice energy by the surplus electric power during the night-time. The experimental apparatus consists of four major parts; (1) the heating section consisting of the air duct and I.D. fan, (2) the cold section with the ice chamber, (3) the bundle of heat pipes made in a form of the staggered arrangement with ${C_y}/{d_o}$=2.0 and ${C_x}/{d_o}$=1.73, (4) the refrigerator system to cool down the ice chamber. This study involves an intensive experiment concerning the convective heat transfer of the air flow surrounding the bundle of heat pipes. This major experimental parameters are the amount of working fluid, the velocity of air and the working temperature. The major findings of the present study are as follows; (1) The optimum amount of the working fluid necessary for the horizontal heat pipes is much more than that for the vertical type. (2) The convective heat transfer coefficients of the air are coincided with the empirical equations of Grimson and ${\breve{Z}ukauskas}$. (3) The equation of the mean heat transfer coefficient obtained in the present study is ${N_um}=0.32 {Re_max^{0.63}}$.

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Vegetation Structure and Ecological Succession of Kojedo District, Hallyo-Haesang National Park (한려해상국립공원 거제도지구 산림군집구조 및 천이계열)

  • 이경재;김보현;김동완
    • Korean Journal of Environment and Ecology
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    • v.12 no.4
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    • pp.331-344
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    • 1999
  • To study plant community structure and successional sere of the Kojedo District, Hallyo-Haesang National Park, fifty six plots were set up and surveyed(each plot $l00\m^2$). Fifty-six plots were classified into four community, Quercus variabilis-Zelkova serrata community(I), Q. variabilis-Cinnamomum japonicum-Neolitsea sericea community(II), Pinus thunbergii-C. japonicum-N. sericea community(III), P. thunbergii-P. densiflora community(IV) by TWINSPAN technique. Most area of forests in Kojedo district are artificial or coppice forest after artificial disturbance. The age of four community were about 35~40 years and the number of species 32~44 species per $600\m^2$. Ecological succession had been proceeded from deciduous broad-leaved species(Q. variabilis-Z. serrata etc.), P. thunbergii, P. densiflora to evergreen broad leaved forest(C. japonicum, N. sericea etc.).

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