• Reproductive and Developmental Biology
• /
• v.32 no.1
• /
• pp.45-49
• /
• 2008

We have previously produced transgenic (TG) mice expressing the human lactoferrin (hLF), interleukin-10 (hIL-10), and thrombopoietin (hTPO) proteins in the milk. In this study, we examined whether simple crossbreeding between two kids of a single transgenic mouse can produce double transgenics co-expressing two human proteins.. The hLF male, and the hIL-10 male were crossbred with the hIL-10 and hTPO females, and the hTPO female, respectively. PCR analysis for genotyping showed 32%, 23% and 24% double transgenic rates for hLF/hIL-10, hLF/hTPO, and hIL-10/hTPO transgenes, respectively. We analyzed the expression levels of the human proteins from double transgenic mice and compared those with their single transgenic siblings. All double transgenic co-expressed two human proteins at comparable levels to singles', unless hTPO was not co-expressed: for hLF, 1.1 mg/ml in hLF/hIL-10, whereas 0.5 mg/ml in hLF/hTPO; for hIL-10, 4.1 mg/ml in hIL-10/hLF, whereas 1.4 mg/ml in hIL-10/hTPO. Ihe downregulation of hTPO to half level of singles' was observed in double transgenic mice. The possible reason why hTPO co-expressed might lead to down-regulation of another human protein was discussed. These results suggested that double transgenic generated by crossbreeding between two singles' could be useful system for bioreactor.

• The Journal of Korean Medicine
• /
• v.26 no.1 s.61
• /
• pp.11-17
• /
• 2005

This study was carried out to identify the components of the human heart meridian muscle, the regional muscle group being divided into outer, middle, and inner layers. The inner parts of the body surface were opened widely to demonstrate muscles, nerves, blood vessels and to expose the inner structure of the heart meridian muscle in the order of layers. We obtained the following results; $\cdot$ The heart meridian muscle is composed of muscles, nerves and blood vessels. $\cdot$ In human anatomy, the difference between terms is present (that is, between nerves or blood vessels which control the meridian muscle and those which pass near by). $\cdot$ The inner composition of the heart meridian muscle in the human arm is as follows: 1) Muscle H-l: latissimus dorsi muscle tendon, teres major muscle, coracobrachialis muscle H-2: biceps brachialis muscle, triceps brachialis muscle, brachialis muscle H-3: pronator teres muscle and brachialis muscle H-4: palmar carpal ligament and flexor ulnaris tendon H-5: palmar carpal ligament & flexor retinaculum, tissue between flexor carpi ulnaris tendon and flexor digitorum superficialis tendon, flexor digitorum profundus tendon H-6: palmar carpal ligament & flexor retinaculum, flexor carpi ulnaris tendon H-7: palmar carpal ligament & flexor retinaculum, tissue between flexor carpi ulnaris tendon and flexor digitorum superficial is tendon, flexor digitorum profundus tendon H-8: palmar aponeurosis, 4th lumbrical muscle, dorsal & palmar interrosseous muscle H-9: dorsal fascia, radiad of extensor digiti minimi tendon & extensor digitorum tendon 2) Blood vessel H-1: axillary artery, posterior circumflex humeral artery H-2: basilic vein, brachial artery H-3: basilic vein, inferior ulnar collateral artery, brachial artery H-4: ulnar artery H-5: ulnar artery H-6: ulnar artery H-7: ulnar artery H-8: palmar digital artery H-9: dorsal digital vein, the dorsal branch of palmar digital artery 3) Nerve H-1: medial antebrachial cutaneous nerve, median n., ulnar n., radial n., musculocutaneous n., axillary nerve H-2: median nerve, ulnar n., medial antebrachial cutaneous n., the branch of muscular cutaneous nerve H-3: median nerve, medial antebrachial cutaneous nerve H-4: medial antebrachial cutaneous nerve, ulnar nerve H-5: ulnar nerve H-6: ulnar nerve H-7: ulnar nerve H-8: superficial branch of ulnar nerve H-9: dorsal digital branch of ulnar nerve.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.12 no.3
• /
• pp.239-245
• /
• 2002

In this Paper, we present a method for designing fuzzy $H_2/H_{\infty}$ controllers of delayed nonlinear systems with saturating input. Takagi-Sugeno fuzzy model is employed to represent delayed nonlinear systems with saturating input. The fuzzy control systems utilize the concept of the so-called parallel distributed compensation(PDC). Using a single quadratic Lyapunov function, the globally exponential stability and $H_2/H_{\infty}$ performance problem are discussed. And a sufficient condition for the existence of fuzzy $H_2/H_{\infty}$ controllers is given in terms of linear matrix inequalities(LMIs). The designing fuzzy $H_2/H_{\infty}$ controllers minimize an upper bound on a linear quadratic performance measure. Finally, a design example of fuzzy $H_2/H_{\infty}$ controller for uncertain delayed nonlinear systems with saturating input.

• Communications of the Korean Mathematical Society
• /
• v.27 no.1
• /
• pp.69-76
• /
• 2012

Let R be a ring, and ${\alpha}$ be an endomorphism of R. An additive mapping H : R ${\rightarrow}$ R is called a left ${\alpha}$-multiplier (centralizer) if H(xy) = H(x)${\alpha}$(y) holds for all x,y $\in$ R. In this paper, we shall investigate the commutativity of prime and semiprime rings admitting left ${\alpha}$-multiplier satisfying any one of the properties: (i) H([x,y])-[x,y] = 0, (ii) H([x,y])+[x,y] = 0, (iii) $H(x{\circ}y)-x{\circ}y=0$, (iv) $H(x{\circ}y)+x{\circ}y=0$, (v) H(xy) = xy, (vi) H(xy) = yx, (vii) $H(x^2)=x^2$, (viii) $H(x^2)=-x^2$ for all x, y in some appropriate subset of R.

• Kyungpook Mathematical Journal
• /
• v.48 no.4
• /
• pp.529-543
• /
• 2008

It is shown that every almost linear mapping h : $A{\rightarrow}B$ of a unital PoissonC*-algebra A to a unital Poisson C*-algebra B is a Poisson C*-algebra homomorph when $h(2^nuy)\;=\;h(2^nu)h(y)$ or $h(3^nuy)\;=\;h(3^nu)h(y)$ for all $y\;\in\;A$, all unitary elements $u\;\in\;A$ and n = 0, 1, 2,$\codts$, and that every almost linear almost multiplicative mapping h : $A{\rightarrow}B$ is a Poisson C*-algebra homomorphism when h(2x) = 2h(x) or h(3x) = 3h(x for all $x\;\in\;A$. Here the numbers 2, 3 depend on the functional equations given in the almost linear mappings or in the almost linear almost multiplicative mappings. We prove the Cauchy-Rassias stability of Poisson C*-algebra homomorphisms in unital Poisson C*-algebras, and of homomorphisms in Poisson Banach modules over a unital Poisson C*-algebra.

• Nuclear Engineering and Technology
• /
• v.11 no.1
• /
• pp.1-20
• /
• 1979

Neutron inelastic scattering studies on polycrystalline hydrates, NaBr-2$H_2O$ and BaCl$_2$-2$H_2O$ have been performed to observe librational modes. Assuming all observed peaks are from the $H_2O$ librational origin, the weighted frequency distribution functions are obtained by eliminating the contributions from the higher order processes. All of theoretical frequencies obtained using FG matrix method are dus to highly mixed modes, and therefore the modes identified as significant $H_2O$ librationat modes from their large potential energy distributions are assigned to the observed peaks. The H-bond interactions are estimated using a modified Lippincott Schroeder potential function, and the applicability of the potential function to the H-bond with highly bent or bifurcated configuration is examined on the basis of the shape of $H_2O$ librational potential energies. Some discussions are given on the usefulness of introducing O-H…Y bending terms in addition to the H…Y stretching in similar frequency calculation in order to obtain more information on the nature of H-bond. Also the purity and symmetry properties of the $H_2O$ librational modes are discussed using group theoretical analyses.

• The Research Journal of the Costume Culture
• /
• v.17 no.6
• /
• pp.992-1008
• /
• 2009

This study is to present a female high school summer blouse with high movement functionality and satisfying appearance. For the experimental research 6 subjects with closest average body shapes and their body surface was measured at beginning and after selecting a representative movement the tested uniform was worn and the appearance and movement functionality was evaluated. The results of this research are as follows. In the research with the aims to improve the sleeve designed the height in 3 types as A.H/4+3, A.H/4+2, A.H/4+1 and their evaluation showed that in the order of best appearance was A.H/4+2, A.H/4+1, A.H/4+3. In the order of best comfort was A.H/4+2, A.H/4+3, A.H/4+1 and the best order for movement functionality was A.H/4+1, A.H/4+2, A.H/4+3. Additional height types designed produced from elastic materials were A.H/4+3, A.H/4+2, A.H/4+1 and the resulting order of appearance was A.H/4+3, A.H/4+2, A.H/4+1, order of comfort was A.H/4+3, A.H/4+2, A.H/4+1 and the order of movement functionality was A.H/4+1, A.H/4+2, A.H/4+3. Integrating these results shows that in using the same concurrent materials, the experiment pattern of setting the sleeve height as A.H/4+2 was the best while in using elastic materials, the experiment pattern of setting the sleeve height as A.H/4+3 was the best.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.25 no.6
• /
• pp.1069-1078
• /
• 2001

Pattern grading is a technique used to increase or decrease the size of a garment pattern according to the measurements in a given size chart. The original pattern is graded and laid out for cutting before mass production. This study tried to classify body types for pattern grading of jacket by applying a concept of "drop"defined as the difference between chest girth and waist girth and the difference between hip girth and waist girth for pants. Data were collected through the stratified sampling method. 138 subjects were selected out of 1,290 subjects of our sample population. Findings were as follows : 1) For pattern grading of jacket, the cell with the chest girth of 96cm and the waist girth of 87cm had the highest frequency rate and body type was 87H type and the coverage of this type was 9.52%. Then, the size specification 87-96 was the center of distribution. H type had seven ones such as 72H, 75H, 78H, 81H, 84H. 87H and 90H. H type had 33 observations and frequency ratio of 26.19%. Same types could be graded up and down from the reference size for the age group. And this reference size became to the starting point for developing the grading system. 2) For pattern grading of pants, fatty types, H10 type had six ones such as 80H10. 82H10, 84H10, 86H10, 88H10 and 90H10. H10 type had 28 observations and frequency ratio of 20.29%. H6 type had 6 ones such as 84H6, 86H6, 88H6, 90H6. 92H6 and 94H6. H6 type had 27 observations and frequency ratio of 19.57%. If lower body types were classified as same ones, these types could be graded up and down proportionately.

• ALGAE
• /
• v.17 no.1
• /
• pp.21-31
• /
• 2002

Five species of Hypoglossum from the coasts of Korea were described. They were distinguished each other by vegetative morphology as well as reproductive structures. H. barbatum Okamura and H. simulans Wynne, Price et Ballantine were similar in their subalternate branchings but they were clearly different by developmental mode of 3rd-order cell rows. H. simulans is distinguished from H. barbatum as well as from the other three species in that only innermost cells of 2nd-order rows cut off 3rd-order cell rows. H. geminatum Okamura and H. caloglossoides Wynne et Kraft are oppositely branched but the latter is characterized by regular constrictions at branching points. H. minimum Yamada developed simple blades. Among them, H. simulans, H. caloglossoides, and H. minimum are newly recorded from Korean waters.

• Animal Systematics, Evolution and Diversity
• /
• v.23 no.2
• /
• pp.169-173
• /
• 2007

Two new marine sponges in the family Chalinidae, Haliclona (Haliclona) uljinensis n. sp. and Haliclona (Reniera) hongdoensis n. sp., are collected from Uljin and Hongdo Island, Korea during 2004-2007. H. (H.) uljinensis n. sp. is closely related to H. (H.) oculata in type of spicules. However, ectosomal skeleton of H. (H.) uljinensis n. sp. is reticulated and isodictyal reticulated type but H. (H.) oculata has not any dermal specialization in skeleton. The growth form of H. (H.) uljinensis n. sp. is thin encrusting with numerous cylindrical tubes on the surface but H. (H.) oculata is solid branch form. Haliclona (R.) hongdoensis n. sp. is closely related to H. (R.) aquaeductus in skeletal structure and growth form. However, oxeas of H. (R.) hongdoensis n. sp. are larger than H. (R.) aquaeductus's.