• Title/Summary/Keyword: $Vs^{30}$

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LC/MS/MS Method for the Determination of Lidocaine in Hairless Rat Plasma and Pharmacokinetic Applications of Lidocaine Patch (LC/MS/MS를 이용한 혈장 중 리도카인의 정량 및 리도카인 패치제의 약물동태학적 평가)

  • Hwang, Ji-Yeon;Kim, Chul-Jun;Shin, Young-Hee
    • YAKHAK HOEJI
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    • v.56 no.3
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    • pp.158-163
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    • 2012
  • Lidocaine has been studied for many chronic pain conditions, including postherpetic neuralgia (PHN) and recently it has also been increasingly used in transdermal drug delivery systems. In this study, pharmacokinetics of a lidocaine patch was studied in four hairless male rats. The plasma concentration was determined by a validated LC/MS/MS method after applying a $3{\times}2cm^2$ (30mg) patch for 12 hours. From the plasma lidocaine concentration vs time curves, $AUC_{0-20h}$, Cmax, and Tmax of lidocaine patch were $2,926.32{\pm}335.28ng{\cdot}h/ml$, $256.86{\pm}29.63ng/ml$, and $6.00{\pm}2.31h$, respectively.

A Case Study of Remaining Life Assessment for Boiler Header (고온 보일러 헤더의 잔여수명평가 사례 연구)

  • Baek, U.B.;Lee, H.M.;Park, J.S.;Kim, D.J.;Yoon, K.B.
    • Proceedings of the KSME Conference
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    • 2001.06a
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    • pp.274-279
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    • 2001
  • Creep-fatigue crack growth behavior was experimentally measured particularly when a crack was located in the heat affected region of 1Cr-0.5Mo steel. Load hold times of the tests for trapezoidal fatigue waveshapes were varied among 0, 30, 300 and 3,600 seconds. Time-dependent crack growth rates were characterized by the $C_t$-parameter. It was found that the crack growth rates were the highest when the crack path was located along the fine-grained heat affected zone(FGHAZ). Cracks located in other heat affected regions had a tendency to change the crack path eventually to FGHAZ. Creep-fatigue crack growth law of the studied case is suggested in terms of $(da/dt)_{avg}$ vs. $(C_t)_{avg}$ for residual life assessment.

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Characteristics of Sparkover Discharge in Flowing Air with Reynolds Numbers' Variable (Reynolds Number를 변수(變數)로한 유동공기(流動空氣)의 방전특성(放電特性)에 관한 연구)

  • Kim, Y.H.;Oh, J.Y.;Lee, K.S.;Lee, D.I.
    • Proceedings of the KIEE Conference
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    • 1990.07a
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    • pp.286-288
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    • 1990
  • This paper reports the characteristics of sparkover discharge in flowing air ranging from 0[m/s] to 30 [m/s] under the needle-needle gap. Flowing air duct of this investigation is circular tube. The important results obtained form this study are as follows. 1. the ratio of sparkover voltage to the Reynolds number decreases with increasing the Reynolds number. 2. The duration time of sparkover(t) decreases with increasing the Reynolds number. 3. the empirical equation obtained form this experiment is [ %]${\frac{Vs}{Re}}$ = A + $B{\varepsilon}^{C.Re}$ where A = 10.2 b = 125 c = -4.66 ${\times}$ $10^{-5}$

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Korean Short Form Negation and Related Phenomena: A Lexicalist, Constraint-Based Analysis

  • Kim, Jong-Bok
    • Language and Information
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    • v.3 no.2
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    • pp.13-30
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    • 1999
  • There have been two opposing views on the structure of the so-called head internal relative construction(HIRC) in Korean/Japanese, i.e., a view that analyzes the HIRC categorially as a nominal projection and functionally as an argument(Kuroda 1992, Watanabe 1992, Hoshi 1996, Jhang 1991/1994, among others) vs. a view that analyzes the HIRC categorially as an adjunct clause and functionally as a non-argument(Murasugi 1994). This paper on the one hand points out several phenomena indicating that Murasugi's analysis is more viable, while on the other hand proposing a more complex structure than Murasugi's to account for other facts as well. The no/kes clause in the HIRC will be analyzed as the complement of a null perception verb whose projection constitutes part of an adjunct clause.

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A Study on the Comparison of Conventional Blasting vs. Air-Tubes Blasting in Limestone Quarry (석회석 광산에서의 일반발파와 에어튜브(Air Tubes)발파 비교 연구)

  • Kim, Yong-Kyun;Lee, Jong-Sik;Lee, Shin;Kang, Dae-Woo
    • Explosives and Blasting
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    • v.21 no.2
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    • pp.31-42
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    • 2003
  • 본 연구는 일반건설현장에서와는 달리 천공경이 $97mm{\Phi}$이상이고 천공장이 21M이상인 상태에서 발파작업이 진행되고 있는 석회석 광산에서 기존의 발파공법과 Air tubes를 이용한 발파공법을 비교하여 기존의 발파로 인한 상부 대괴를 감소시키고 폭약의 사용량을 줄이면서 진동 및 폭음을 최소화하여 보다 경제적인 작업수행을 하기 위해 연구하였다. 한편 에어층(Air deck)을 형성으로 인한 전색장의 길이 감소를 보완하기 위해 라바플러그(Rubber Plug)를 사용하므로 비석의 위험을 최소화 시키고 가스압이 암전체에 충분히 전달할 수 있도록 장치를 만들어 실험하였다. 그 결과 일반발파와 Air tubes를 이용한 발파방법을 비교하여 볼 때 Air tubes를 이용한 발파방법이 폭약을 약 15~30% 절감 할 수 있었으며, 또한 진동은 최대 50%정도의 감소와 폭음에서는 2~5dB 정도로 감소되었다.

Synthesis of $\beta$-SiC Whiskers by the Carbothermal Reduction of Kaolin (카올린의 환원 열탄화법에 의한 베타 탄화규소 휘스커의 합성)

  • 오세정;류종화;조원승;최상욱
    • Journal of the Korean Ceramic Society
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    • v.35 no.12
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    • pp.1249-1256
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    • 1998
  • ${\beta}$-Silicon carbide(${\beta}$-SiC) whiskers could be synthesized by the carbothermal reduction of kaolin at tem-peratures between 1400 and 1500$^{\circ}C$. The whiskers were grown up to about 1150 of aspect ratio by VS mechanism (showing tapering tips) and to about 45 of that by VLS mechanism (showing round droplet tips) respectively. Hydrocarbon like methane in the reaction atmosphere promoted the formation of gaseous il-icon monoxide(SiO) from silicon dioxide(SiO2) and subsequently reacted with it to form whiskers. The for-mation of ${\beta}$-SiC whiskers increased with increasing carbon content(to 30 wt%) and reaction temperatures. The max. yield of ${\beta}$-SiC whiskers was 15% at 1500$^{\circ}C$ under 20%CH4/80%H2.

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Statistical Evaluation of Fracture Characteristics of RPV Steels in the Ductile-Brittle Transition Temperature Region

  • Kang, Sung-Sik;Chi, Se-Hwan;Hong, Jun-Hwa
    • Nuclear Engineering and Technology
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    • v.30 no.4
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    • pp.364-376
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    • 1998
  • The statistical analysis method was applied to the evaluation of fracture toughness in the ductile-brittle transition temperature region. Because cleavage fracture in steel is of a statistical nature, fracture toughness data or values show a similar statistical trend. Using the three-parameter Weibull distribution, a fracture toughness vs. temperature curve (K-curve) was directly generated from a set of fracture toughness data at a selected temperature. Charpy V-notch impact energy was also used to obtain the K-curve by a $K_{IC}$ -CVN (Charpy V-notch energy) correlation. Furthermore, this method was applied to evaluate the neutron irradiation embrittlement of reactor pressure vessel (RPV) steel. Most of the fracture toughness data were within the 95% confidence limits. The prediction of a transition temperature shift by statistical analysis was compared with that from the experimental data.

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Identification of Chicken Pork and Beef Meats by Chicken Specific Antibody (계육 특이항체를 이용한 원료육 단백질의 검색)

  • 임태진
    • Food Science of Animal Resources
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    • v.18 no.2
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    • pp.149-156
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    • 1998
  • Chicken beef pork meats and isolated soy protein (ISP) were heated at 10$0^{\circ}C$ for 30min and then heat-resistant proteins were fractionated to examine cross-resistant protein from chicken meat but not with beef pork or ISP. Dot blotting using the polyclonal antibody showed that the sen-sitivity for detecting chicken meat was 1$\mu$m and antibody-antigen reaction was dose-dependant. Results of dot blotting analysis to compare the amount of chicken meat present in arket meat products(Kentucky Frank sausage;chicken meat 46.52% and pork 24.92% vs Bulgogi Ham;chicken meat 28.89% and turkey 31.44%)showed that the significant differences between two meat products in terms of chicken meat concentrations. Dose-dependant dot-blotting reaction was also observed in chicken meat samples with various dilution.

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Fabrication of Sub-$10{\mu}m$ Screen Printed Organic Thin-Film Transistors on Paper

  • Jo, Jeong-Dai;Yu, Jong-Su;Yun, Seong-Man;Kim, Dong-Soo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.896-898
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    • 2009
  • The printed electrodes of organic thin-film transistors (OTFTs) were fabricated by screen printing using nanoparticle silver pastes. The screen printed OTFT corresponds to channel lengths between 7.6 to 82.6 ${\mu}m$ (designed L=10 to 80 ${\mu}m$) on the $150{\times}150mm^2$ paper. The channel length deviations for 40 to 80 ${\mu}m$ patterns were less than 5 %. However, the channel lengths for 10 to 30 ${\mu}m$ patterns were increased by 20 %. The screen printed bis(triisopropyl-silylethynyl) pentacene (TIPS-pentacene) OTFTs obtained had a field-effect mobility as large as 0.08 (${\pm}0.02$) $cm^2$/Vs, an on/off current ratio of $10^5$ and a subthreshold slope of 1.95 V/decade.

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First reliable record of Liparis punctulatus (Scorpaeniformes: Liparidae) in Korea

  • Park, Gyeong Hyun;Kim, Jin-Koo
    • Fisheries and Aquatic Sciences
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    • v.24 no.5
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    • pp.191-196
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    • 2021
  • A single specimen of Liparis punctulatus (30.9 mm standard length) belonging to the family Liparidae, was collected in the waters off Busan on 4 August, 2016. This species is characterized by a single pair of nostrils, unlike other Liparis species. It is distinguished from L. ochotensis by the numbers of dorsal, anal, pectoral fin rays and the location of the gill opening (above the pectoral fin in L. punctulatus vs. extending ventrally in front of the pectoral fin). In the molecular analysis, 514 bp of 16S rRNA gene of the specimen in this study were identical to that of L. punctulatus from NCBI GenBank (K2P distance < 0.002). This is the first record of the species in Korea based on a voucher specimen, and we follow the Korean name "Kko-ma-kkom-chi" for this species proposed by Myoung et al. and Kim et al.