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Comparison of Intraoperative Somatosensory Evoked Potential(SSEP) Monitoring During Aneurysm Surgery : ACA Aneurysms vs MCA Aneurysms (전대뇌동맥과 중대뇌동맥 동맥류 수술시 체성감각유발전위의 모니터링의 비교, 분석)

  • Choi, Kwang Yeong;Kim, Gook Ki;Lim, Young Jin;Kim, Tae Sung;Leem, Won;Rhee, Bong Arm
    • Journal of Korean Neurosurgical Society
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    • v.30 no.sup2
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    • pp.281-288
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    • 2001
  • Objectives : The purpose of this study is to evaluate the usefulness of SSEP monitoring during intracranial aneurysm surgery and compare the characteristics of wave change in relation to neurologic changes between ACA aneurysms and MCA aneurysms. Methods : During recent three years(between January 1997 and November 1999), intraoperative SSEP monitoring had been done in 63 operations for intracranial aneurysms. We had monitored the median nerve SSEP during surgery for aneurysms of MCA and the posterior tibial nerve SSEP for aneurysms of ACoA or ACA. A more than 50% reduction of any cortical SEP response was considered to be a significant SEP change, compared to its baseline value before the start of surgery. Changes in the SEPs were categorized as follows : Type IA, no significant amplitude changes without temporary clipping ; Type IB, no significant amplitude changes with temporary clipping ; Type II, significant changes with temporary clipping and complete return to control amplitude ; Type III, significant changes with temporary clipping and incomplete return to control amplitude ; Type IV, significant changes with temporary clipping and more decreased amplitude changes. Results : Among the 63 intraoperative monitoring, there were 37 cases of ACA aneurysms(An), and 26 of MCA An. The temporary proximal arterial occlusion during surgery were performed in 31(83.8%)cases of ACA An, 22(84.6%) of MCA An. Seven of the 31 ACA An(22.6%) and ten of the 22 MCA An(45.5%) had significant changes. The type were as follows : 4 patients with type II and 3 with type III in the ACA An ; 3 patients with type II and 3 with type III and 4 with type IV in the MCA An. In both group type II changes had no new postoperative neurological deficit. All 6 patients with type III had new neurological deficits ; However, One case in the ACA An and two cases in the MCA An. had transient neurologic deficit and improved markedly over the next two months. All 4 type IV changes in the MCA An. had permanant neurologic deficits. Two out of 30 cases(6.7%) in the ACA An. and one out of 16 cases(6.3%) in the MCA An. without significant amplitude change had new neurologic deficit postoperatively. Conclusion : Based on this study, Intraoperative SSEP monitoring during aneurysm surgery would provide useful information for detecting cerebral ischemia. SSEP response during surgery for MCA An. is more sensitive than ACA An. Otherwise, there were no meaningful difference in rate of false negativity.

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Early fragment removal on in vitro fertilization day 2 significantly improves the subsequent development and clinical outcomes of fragmented human embryos

  • Kim, Seok-Gi;Kim, Youn-Young;Park, Ji-Young;Kwak, Su-Jin;Yoo, Chang-Seok;Park, Il-Hae;Sun, Hong-Gil;Kim, Jae-Won;Lee, Kyeong-Ho;Park, Hum-Dai;Chi, Hee-Jun
    • Clinical and Experimental Reproductive Medicine
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    • v.45 no.3
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    • pp.122-128
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    • 2018
  • Objective: To determine whether fragment removal on in vitro fertilization (IVF) day 2 improved the subsequent development and pregnancy outcomes of fragmented embryos compared to similar-grade embryos without fragment removal. Methods: This study was a retrospective analysis involving 191 IVF cycles in which all embryos had over 10% fragmentation (grade 3 or 4) on day 2 of the IVF-embryo transfer cycle from March 2015 to December 2017. IVF cycles were divided into the fragment removal group (n = 87) and the no fragment removal group (n = 104) as a control cohort. Before fragment removal, embryos with fragmentation on day 2 were incubated in $Ca^{2+}$- and $Mg^{2+}$-free biopsy medium under paraffin oil for 30 minutes. Microsurgical fragment removal was performed with later-assisted hatching and a handmade suction micropipette that had an outer diameter of $30{\mu}m$. Results: There were no significant differences in the characteristics of the patients between the control and the fragment removal groups. After fragment removal and subsequent in vitro culture for 24 hours, the number of blastomeres ($7.1{\pm}1.7$ vs. $6.9{\pm}1.6$) was comparable between the transferred embryos in the two groups, but the morphological grade of the embryos in the fragment removal group ($1.9{\pm}0.7$) was significantly higher than that of the control group ($3.1{\pm}0.5$, p< 0.01). The clinical pregnancy (43.7%) and implantation rates (25.8%) in the fragment removal group were significantly higher than those in the control group (28.8% and 14.0%, respectively; p< 0.05). Conclusion: Early fragment removal on day 2 significantly improved the subsequent development and pregnancy outcomes of fragmented embryos.

Relations of Married Women and their Own Parents in Japan: Coresidence and Contact Frequency (일본 기혼여성들과 친정부모간의 세대관계: 동거여부 및 대화빈도를 중심으로)

  • Kim, Cheong-Seok;Cho, Yoon-Joo
    • Korea journal of population studies
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    • v.35 no.2
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    • pp.55-72
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    • 2012
  • Few studies have done on the intergenerational relations of married women and their own parents in Japan. This study approaches the topic by examining coresidence and contact frequency between generations. The study expects the likelihood of living together (including living next door) and the extent of contact would differ by the characteristics of woman, her husband, children, her brothers and sisters, her own parents and parents-in-law. From the 2003 Survey for National Family Research in Japan, selected are 853 currently married women in their 30s and 40s whose parent and parents-in-law are alive. The analysis shows that the likelihood of living together with parents decreases as the number of brothers and sisters increases. In particular, the presence of brother substantially decreases the likelihood. Having father only alive (vs. having both parents alive) also increases the likelihood. The frequency of contact with parents is conditioned by the coresidence with parents-in-law. It also differs by the level of education and its gap between spouses. Subjective evaluation of husband's attitude toward her parents is important. As in the case of living together, the number of brothers and sisters and the survival status of parents are significant in explaining the frequency of contact with her parents. The results indicate that number of brothers and sisters as well as widowhood of parents serves as its demographic condition. The findings that the frequency of contact with parent are affected by coresidene with parents-in-law, education gap between spouses and husband's attitude toward her parents suggest that the relationship of married women with her own parents are conditioned by her husband and his parents.

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Study on Characteristics of Biogas Production and Liquid Fertilizer with Anaerobic Co digestion of Livestock Manure and Food Waste (혐기성소화에서 가축분뇨와 음식물쓰레기의 혼용에 따른 바이오가스 생산 및 소화액의 액비 특성 연구)

  • Park, Woo-Kyun;Park, Noh-Back;Shin, Joung-Du;Hong, Seung-Gil;Kwon, Soon-Ik;Kang, Kee-Kyung
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.5
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    • pp.895-902
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    • 2011
  • Objective of this research was to investigate the characteristics of biogas production in anaerobic digestion reactor with different mixing ratio of food waste and swine manure. It was observed that the highest removal efficiency of organic material was 80% at 60 : 40 of mixing ratio (livestock manure : food waste). And also biogas yield was varied due to different mixing ratio of them. The cumulative biogas yield was highest at 60 : 40 of mixing rate (livestock manure : food waste). For use of the liquefied fertilizer as effluent from anaerobic digester, it was the limited ratio for 30% of co-digested food waste based on its salt content.

Effect of phytol in forage on phytanic acid content in cow's milk

  • Lv, Renlong;Elsabagh, Mabrouk;Obitsu, Taketo;Sugino, Toshihisa;Kurokawa, Yuzo
    • Animal Bioscience
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    • v.34 no.10
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    • pp.1616-1622
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    • 2021
  • Objective: Bioactive compounds in ruminant products are related to functional compounds in their diets. Therefore, this study aimed to explore the effect of forage sources, Italian ryegrass (IR) silage vs corn silage (CS) in the total mixed ration (TMR), on milk production, milk composition, and phytanic acid content in milk, as well as on the extent of conversion of dietary phytol to milk phytanic acid. Methods: Phytanic acid content in milk was investigated for cows fed a TMR containing either IR silage or CS using 17 cows over three periods of 21 days each. In periods 1 and 3, cows were fed CS-based TMR (30% CS), while in period 2, cows were fed IR silage-based TMR (20% IR silage and10% CS). Results: The results showed that there were no differences in fat, protein, lactose, solids-not-fat, somatic cell count, and fatty acid composition of milk among the three experimental periods. There were no differences in the plasma concentration of glucose, triglycerides, total cholesterol, and nonesterified fatty acids among the three experimental periods, while the blood urea nitrogen was higher (p<0.05) in period 2. The milk phytanic acid content was higher (p<0.05) in period 2 (13.9 mg/kg) compared with periods 1 (9.30 mg/kg) and 3 (8.80 mg/kg). Also, the phytanic acid content in the feces was higher (p<0.05) in period 2 (1.65 mg/kg dry matter [DM]) compared with period 1 (1.15 mg/kg DM), and 3 (1.17 mg/kg DM). Although the phytol contents in feces did not differ among the three feeding periods, the conversion ratio from dietary phytol to milk phytanic acid was estimated to be only 2.6%. Conclusion: Phytanic acid content in cow's milk increases with increasing phytol content in diets. However, phytol might not be completely metabolized in the rumen and phytanic acid, in turn, might not be completely recovered into cow's milk. The change of phytanic acid content in milk may be positively correlated with the change of phytol in the diet within a short time.

Fire Detection using Deep Convolutional Neural Networks for Assisting People with Visual Impairments in an Emergency Situation (시각 장애인을 위한 영상 기반 심층 합성곱 신경망을 이용한 화재 감지기)

  • Kong, Borasy;Won, Insu;Kwon, Jangwoo
    • 재활복지
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    • v.21 no.3
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    • pp.129-146
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    • 2017
  • In an event of an emergency, such as fire in a building, visually impaired and blind people are prone to exposed to a level of danger that is greater than that of normal people, for they cannot be aware of it quickly. Current fire detection methods such as smoke detector is very slow and unreliable because it usually uses chemical sensor based technology to detect fire particles. But by using vision sensor instead, fire can be proven to be detected much faster as we show in our experiments. Previous studies have applied various image processing and machine learning techniques to detect fire, but they usually don't work very well because these techniques require hand-crafted features that do not generalize well to various scenarios. But with the help of recent advancement in the field of deep learning, this research can be conducted to help solve this problem by using deep learning-based object detector that can detect fire using images from security camera. Deep learning based approach can learn features automatically so they can usually generalize well to various scenes. In order to ensure maximum capacity, we applied the latest technologies in the field of computer vision such as YOLO detector in order to solve this task. Considering the trade-off between recall vs. complexity, we introduced two convolutional neural networks with slightly different model's complexity to detect fire at different recall rate. Both models can detect fire at 99% average precision, but one model has 76% recall at 30 FPS while another has 61% recall at 50 FPS. We also compare our model memory consumption with each other and show our models robustness by testing on various real-world scenarios.

Relative Association of Overhydration and Muscle Wasting with Mortality in Hemodialysis Patients: Assessment by Bioelectrical Impedance Analysis (혈액투석 환자에서 Bioelectrical Impedance Analysis를 활용하여 측정한 과수분량과 근육량 감소와 사망률의 상관관계)

  • Kim, Eunju;Seo, Sang Oh;Choi, Yu Bum;Lee, Mi Jung;Lee, Jeong Eun;Kim, Hyung Jong
    • The Korean Journal of Medicine
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    • v.93 no.6
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    • pp.548-555
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    • 2018
  • Background/Aims: Assessment of fluid status in hemodialysis patents is very important. Overhydration in hemodialysis is associated with generalized edema, cardiovascular complications, and hypertension. The aim of this study was to determine the factors correlated with mortality of hemodialysis patients, assessing body muscle mass and fluid status using bioelectrical impedance analysis (BIA). Methods: This study enrolled 93 patients who underwent hemodialysis between January 2010 and May 2015 at CHA Bundang Medical Center. Medical records of enrollees up to June 2017 were reviewed retrospectively. These included laboratory results (serum albumin, C-reactive protein [CRP], lipid profile, etc.) and BIA data (extracellular water, intracellular water, total body water, soft lean mass, fat free mass, skeletal muscle mass, etc.). Results: Eleven of 93 patients had expired by May 2017. Among the surviving subjects, mean age was younger, CRP levels were lower, albumin levels were higher, and extracellular water/total body water (ECW/TBW) ratios were lower than in the expired patient group. Kaplan-Meier survival analysis revealed that overhydration (ECW/TBW > 0.4) was associated with higher mortality. Conclusions: In hemodialysis patients, overhydration is an important factor in mortality, and BIA could be a reliable modality in its assessment. We suggest that, for hemodialysis patients, overhydration is more of a risk factor for mortality than is muscle wasting.

Effect of diabetes-specific oral nutritional supplements with allulose on weight and glycemic profiles in overweight or obese type 2 diabetic patients

  • Jihye Tak;Minkyung Bok;Hyunkyung Rho;Ju Hyun Park;Yunsook Lim;Suk Chon;Hyunjung Lim
    • Nutrition Research and Practice
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    • v.17 no.2
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    • pp.241-256
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    • 2023
  • BACKGROUND/OBJECTIVES: Diabetes-specific oral nutritional supplements (ONS) have anti-hyperglycemic effects, while D-allulose exerts anti-diabetic and anti-obesity effects. In this study, we investigated the efficacy and safety of diabetes-specific ONS, including allulose, on glycemic and weight changes in overweight or obese patients with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A single-arm, historical-control pilot clinical trial was conducted on 26 overweight or obese patients with T2DM (age range: 30-70 yrs). The participants were administered 2 packs of diabetes-specific ONS, including allulose (200 kcal/200 mL), every morning for 8 weeks. The glycemic profiles, obesity-related parameters, and lipid profiles were assessed to evaluate the efficacy of ONS. RESULTS: After 8 weeks, fasting blood glucose (FBG) level significantly decreased from 139.00 ± 29.66 mg/dL to 126.08 ± 32.00 mg/dL (P = 0.007) and glycosylated hemoglobin (HbA1c) improved (7.23 ± 0.82% vs. 7.03 ± 0.69%, P = 0.041). Moreover, the fasting insulin (δ: -1.81 ± 3.61 μU/mL, P = 0.017) and homeostasis model assessment for insulin resistance (HOMA-IR) (δ: -0.87 ± 1.57, P = 0.009) levels decreased at 8 weeks, and body weight significantly decreased from 67.20 ± 8.29 kg to 66.43 ± 8.12 kg (P = 0.008). Body mass index (BMI) also decreased in accordance with this (from 25.59 ± 1.82 kg/m2 to 25.30 ± 1.86 kg/m2, P = 0.009), as did waist circumference (δ: -1.31 ± 2.04 cm, P = 0.003). CONCLUSIONS: The consumption of diabetes-specific ONS with allulose in overweight or obese patients with T2DM improved glycemic profiles, such as FBG, HbA1c, and HOMA-IR, and reduced body weight and BMI.

Blade Type Field Vs Probe for Evaluation of Soft Soils (연약지반 평가를 위한 블레이드 타입 현장 전단파 속도 프로브)

  • Yoon, Hyung-Koo;Lee, Chang-Ho;Eom, Yong-Hun;Lee, Jong-Sub
    • Journal of the Korean Geotechnical Society
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    • v.23 no.12
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    • pp.33-42
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    • 2007
  • The assessment of shear wave velocity($V_s$) in soft soils is extremely difficult due to the soil disturbances during sampling and field access. After a ring type field $V_s$ probe(FVP) has been developed, it has been applied at the southern coastal area of the Korean peninsular. This study presents the upgraded FVP "blade type FVP", which minimizes soil disturbance during penetration. Design concerns of the blade type FVP include the tip shape, soil disturbance, transducers, protection of the cables, and the electromagnetic coupling between transducers and cables. The cross-talking between cables is removed by grouping and extra grounding of the cables. The shear wave velocity of the FVP is simply calculated by using the travel distance and the first arrival time. The large calibration chamber tests are carried out to investigate the disturbance effect due to the penetration of FVP blade and the validity of the shear waves measured by the FVP. The blade type FVP is tested in soils up to 30m in depth. The shear wave velocity is measured every 10cm. This study suggests that the upgraded blade type FVP may be an effective device for measuring the shear wave velocity with minimized soil disturbance in the field.

Individualism and collectivism in ethical decision making (문화성향은 윤리적 의사결정의 과정에 영향을 주는가?)

  • Hong Im Shin
    • Korean Journal of Culture and Social Issue
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    • v.21 no.1
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    • pp.67-96
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    • 2015
  • Do cultural differences affect moral decisions? Two studies were conducted to investigate whether attitudes of individualism vs. collectivism have an impact on ethical decision making. Study 1 (N=92) showed that utilitarianism was preferred in a situation, in which an intervention resulted in the best outcome (i.e., saving more people's lives), while deontology was preferred in a situation, in which the focus was on negative consequences of the intervention (i.e. personal sacrifices). Additionally, there were differences between the idiocentrics and the allocentrics groups regarding morality aspects. In the idiocentrics group, harm and fairness were regarded as more important than other moral aspects, while in the allocentrics group, not only harm and fairness, but also ingroup and authority were perceived as critical moral aspects. In Study 2 (N=30), after lexical decision tasks were conducted for culture priming, the mouse tracking method was used to explore response dynamics of moral decision processes, while judging appropriateness of interventions in moral dilemmas. In Study 2, in a condition, in which the small number of victims were focused upon, there were more maximal deviations and higher Xflips in the individualism priming group than in the collectivism priming group, which showed that the participants in the individualism condition had more deliberative processes before choosing their answers between utilitarianism and deontology. In addition, the participants in the individualism priming condition showed more maximal deviations in the mouse trajectories regarding ingroup related interventions in moral dilemmas than those in the collectivism priming condition. These results implicated the possibilities that the automatic emotional process and the controlled deliberative process in moral decision making might interact with cultural dispositions of the individuals and the focus of situations.

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