• Journal of Nutrition and Health
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• v.26 no.5
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• pp.615-624
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• 1993

The body fat distribution and nutritional state of the Korean and Japanese young female subjects were compared. Three-day individually weighed, dietary intakes and anthropometric measurements were determinded in 48 Korean and 60 Japanese female students. 19 to 23 yr of age, from the divisions of nutritions. The body composition estimates were measured by bioeletrical impedance-total body water(BI-TBW) method. There were no significant difference between the Korean and Japanese young females in body size and body shape. The Korean young females had lower estimated total body fat and internal fat that calculated by BI-TBW method, but there was no great difference between the Korean and the Japanese in subcutaneous fat. In contrast, the Korean young females are reported to have the same total energy expenditure per day as the Japanes young females and the total energy intakes and carbohydrate energy intake ratio per day were significantly higher than those of the Japanese young females. The difference in body fat distribution and energy intakes in Korean, and the role of capsaicin in red pepper are discussed as a possible determinant of the internal fat in the Korean vs the Japanese.

• Journal of Korean Neurosurgical Society
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• v.60 no.5
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• pp.604-609
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• 2017

Objective : An adjustable Ghajar guide is presented to improve the accuracy of the original Ghajar guide technique. The accuracy of the adjustable Ghajar guide technique is also investigated. Methods : The coronal adjustment angle from the orthogonal catheter trajectory at Kocher's point is determined based on coronal head images using an electronic picture archiving and communication system. For the adjustable Ghajar guide, a protractor is mounted on a C-shaped basal plate that is placed in contact with the margin of a burrhole, keeping the central $0^{\circ}$ line of the protractor orthogonal to the calvarial surface. A catheter guide, which is moved along the protractor and fixed at the pre-determined adjustment angle, is then used to guide the ventricular catheter into the frontal horn adjacent to the foramen of Monro. The adjustable Ghajar guide technique was applied to 20 patients, while a freehand technique based on the surface anatomy of the head was applied to another 47 patients. The accuracy of the ventricular catheter placement was then evaluated using postoperative computed tomography scans. Results : For the adjustable Ghajar guide technique (AGT) patients, the bicaudate index ranged from 0.23 to 0.33 ($mean{\pm}standard$ deviation [SD] : $0.27{\pm}0.03$) and the adjustment angle ranged from $0^{\circ}$ to $10^{\circ}$ ($mean{\pm}SD:5.2^{\circ}{\pm}3.2^{\circ}$). All the AGT patients experienced successful cerebrospinal fluid diversion with only one pass of the catheter. Optimal placement of the ventricular catheter in the ipsilateral frontal horn approximating the foramen of Monro (grade 1) was achieved in 19 patients (95.0%), while a suboptimal trajectory into a lateral corner of the frontal horn passing along a lateral wall of the frontal horn (grade 3) occurred in 1 patient (5.0%). Thus, the AGT patients experienced a significantly higher incidence of optimal catheter placement than the freehand catheterized patients (95.0% vs. 68.3%, p=0.024). Moreover, none of the AGT patients experienced any tract hemorrhages along the catheter or procedure-related complications. Conclusion : The proposed adjustable Ghajar guide technique, using angular adjustment in the coronal plane from the orthogonal trajectory at Kocher's point, facilitates accurate freehand placement of a ventricular catheter for hydrocephalic patients.

• Journal of Yeungnam Medical Science
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• v.35 no.1
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• pp.76-83
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• 2018

Background: Elderly patients with multiple myeloma (MM) are vulnerable to adverse events (AEs). This study evaluated adherence to chemotherapy and treatment outcomes in elderly patients treated with a frontline bortezomib (BTZ), melphalan, and prednisone (VMP) regimen and regimens without BTZ. Methods: One-hundred and forty elderly patients who were diagnosed with MM from March 2007 to March 2015 were included in this retrospective study. To evaluate regimen adherence, patients who were treated with more than 4 cycles were assigned to the good adherence group. Results: Among the 140 patients, 71 were treated with a frontline VMP and 69 with non-BTZ regimens. The median age was 71 years (range, 65-90 years). The VMP group showed a higher complete response rate than the non-BTZ group: 26.8% vs. 7.2%. More patients in the VMP group achieved ${\geq}$very good partial response (VGPR) and ${\geq}PR$. In the VMP group, 27 patients (38.0%) received less than 4 cycles. The VMP good adherence group showed a higher 3-year overall survival (OS) rate (70.9%) than the poor adherence group (60.2%, p=0.059). In the multivariate analysis, treatment with ${\geq}4$ cycles of VMP was a favorable factor for OS. Conclusion: A good adherence to a frontline VMP regimen resulted in favorable long-term survival. Adequate management of AEs will be needed to achieve favorable outcomes in elderly patients with MM.

• Korea journal of population studies
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• v.35 no.2
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• pp.55-72
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• 2012

Few studies have done on the intergenerational relations of married women and their own parents in Japan. This study approaches the topic by examining coresidence and contact frequency between generations. The study expects the likelihood of living together (including living next door) and the extent of contact would differ by the characteristics of woman, her husband, children, her brothers and sisters, her own parents and parents-in-law. From the 2003 Survey for National Family Research in Japan, selected are 853 currently married women in their 30s and 40s whose parent and parents-in-law are alive. The analysis shows that the likelihood of living together with parents decreases as the number of brothers and sisters increases. In particular, the presence of brother substantially decreases the likelihood. Having father only alive (vs. having both parents alive) also increases the likelihood. The frequency of contact with parents is conditioned by the coresidence with parents-in-law. It also differs by the level of education and its gap between spouses. Subjective evaluation of husband's attitude toward her parents is important. As in the case of living together, the number of brothers and sisters and the survival status of parents are significant in explaining the frequency of contact with her parents. The results indicate that number of brothers and sisters as well as widowhood of parents serves as its demographic condition. The findings that the frequency of contact with parent are affected by coresidene with parents-in-law, education gap between spouses and husband's attitude toward her parents suggest that the relationship of married women with her own parents are conditioned by her husband and his parents.

• Journal of The Korean Society of Clinical Toxicology
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• v.17 no.2
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• pp.118-125
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• 2019

Purpose: Non-benzodiazepine hypnotic drugs (including zolpidem) are associated with an increased risk of suicide and suicidal ideation. Considering the wide usage of zolpidem, this drug should be considered a possible etiology for stupor or coma in any patient exposed to this drug. However, there are no reports on zolpidem blood levels in emergency department patients in Korea. We therefore reviewed the analyzed data of a toxicology laboratory at one university affiliated hospital. Methods: The sex, age, chief symptoms, suspiciousness of poisoning, and presumption of poison were analyzed from January 2018 to June 2019. The detection frequency and level of zolpidem in the patient blood were compared to the mental changes presented, which is the main consequence of zolpidem. Results: A total of 229 toxicological analyses, requested to a toxicological laboratory at one university affiliated hospital, were reviewed. Among 229 patients, the mean age was 54.3±20.7 years old with 113 women and 116 men. 8.7% of patients have psychiatric illness and 39.7% were poisoned intentionally. The chief symptoms detected were: mental change 55.0%, gastrointestinal 14.4%, cardiovascular 10.5%, focal neurological 7.4%, respiratory 3.5%, none 8.7%, and unknown 0.4%. A request for detailed reports revealed that causative poisons were specified only in 20.1% cases. Zolpidem was detected in 22.3% cases (51/229), with median blood level 1.26 mg/L (interquartile 0.1, 5.06 mg/L) and urine 0.90 mg/L (interquartile 0.11, 5.6 mg/L). Furthermore, zolpidem was more frequently detected in toxicology analysis of patients where mental change was the primary symptom, as compared to other symptoms (32.5% vs. 9.7%, p<0.01). Conclusion: This study reported the blood level of zolpidem in suspected poisoning patients admitted to the emergency department.

• Ecology and Resilient Infrastructure
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• v.8 no.3
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• pp.143-153
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• 2021

The growth inhibition effects of M. aeruginosa were verified using large volume (7.2 L) of algae samples and ultrasonication (high frequency of 1.6 MHz vs. low frequency of 23 kHz) in lab-scale experiment. The chlorophyll-a (chl-a) and cell number decreased gradually after 6 hr sonication with high frequency of 1.6 MHz whereas both decreased sharply after 6 hr sonication with low frequency of 23 kHz. Additionally, the first order degradation coefficient (k) values after sonication were greater than those during sonication. These results indicate that relatively low sonication energy per volume may affect the cell membrane and internal organs of M. aeruginosa in a slow and retarded manner and resulted in gradual decrease of cell numbers of M. aeruginosa. Based on the comparison of chl-a and cell number of M. aeruginosa after sonication, low frequency of 23 kHz is superior for growth inhibition of M. aeruginosa, since low frequency of 23 kHz easily penetrates the cell membrane and ruptures the internal organs including gas vesicles. As is evident in SEM and TEM images, ruptured cell membranes were clearly observed for low frequency of 23 kHz. Finally, the microcystin-LR in water is not detected and considered to be harmless in aquaculture systems.

• International Area Studies Review
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• v.16 no.1
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• pp.53-74
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• 2012

The bundling of multiple products/services at a set price has become a popular marketing strategy. However, little is known on how effects of bundling strategy influence tourists' evaluation of tour packages. Tourists evaluate a tour package based on the trade-off between the perceived benefits and costs involved in purchasing the tour package. In other words, the perceived value of the tour package influenced whether tourists to purchase a tour package or not. This study tested a tour package based on the theory of bundling, taking a moderating approach with perceived value. The data for this study wascollected by subjects who live Seoul Metropolitan Area and Gyeonggi Province and 4234 respondents, potential tourists to northeastern U.S.A/Canada. Results show that bundling taken by travel agencies include how many product items to put in a tour package and what degree of discount for the tour package. Also explaining functional relationship among product items in the tour package. Result show that tourists expect a discount, large or small, from purchasing a tour package. And the larger the number of products in a tour packages, the larger the discount size, and low functional relationship among items tourists expect to get.

• 한국노년학
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• v.32 no.3
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• pp.941-954
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• 2012

Purpose: The purpose of this study was to investigate the prevalence of depression and its' correlates among elderly people(young-old vs old-old) with poverty. Methods: The sample was 434 of young-old elderly and 209 of old-old elderly people who were 60 and over and basic livelihood recipient in Korean urban community. Depression was measured by Geriatric Depression Scale by Yesavage et al.(1983) in Korean Version. Results: The prevalence of depression was greater for old-old people(63.2%) compared to young-old people(53.9%). Multivariate logistic regression analysis shows the difference of correlates of depression between young-old and old-old elderly people. Prevalence of depression in young-old people was associated with renting in housing type; bad self-rated health status; lack of regular leisure activity; lack of regular eating habit, whereas old-old people was affected by lower social support; moderate or bad self-rated health status; lack of regular leisure activity Conclusion: The finding of differences in prevalence of depression and its' correlates between young-old and old-old people is expected to promote the screening strategy for elderly at risk of depression in Korean community elderly with poverty.

• Journal of The Korean Society of Clinical Toxicology
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• v.18 no.2
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• pp.78-84
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• 2020

Purpose: In acute acetaminophen poisoning, the administration of N-acetylcysteine (NAC) can effectively treat the main complications, such as kidney injury and liver failure. In the current situation, measurements of the acetaminophen concentration are not checked in the usual medical facilities. Therefore, this study examined the factors of determining the administration of NAC in addition to the stated amount of intake. Methods: The medical records of patients who visited Ajou University Hospital emergency center with acetaminophen poisoning from January 2015 to December 2019 were reviewed retrospectively. One hundred and seventy-nine patients were initially included. Among these patients, 82 patients were finally selected according to the inclusion criteria in the study. The inclusion criteria were as follows: patients who were 15 years of age or older; those whose ingested dose, ingested time, and body weight were clearly identified; and patients whose acetaminophen sampling time was within 24 hours. Patients were divided into two groups: NAC administered vs. non-NAC administered. The following variables were compared in these two groups: ingested dose, ingested dose per body weight, hospital arrival time after ingestion, suicide attempt history, psychiatric disease history, classification of toxic/non-toxic groups, duration of hospitalization, and laboratory results. Results: Univariate analysis revealed the ingested dose per body weight, hospital arrival time after ingestion, suicide attempt history, and psychiatric disease history to be the determining factors in administering NAC. Logistic regression analysis confirmed that the ingested dose per body weight was the only significant factor leading to an NAC treatment decision. (Odds ratio=1.039, 95% Confidential interval=1.009-1.070, p=0.009) Conclusion: The ingested dose per body weight was the only determining factor for administering NAC in patients with acute acetaminophen poisoning. On the other hand, additional criteria or indicators for the NAC administration decision will be necessary considering the inaccuracy of the ingested dose per body weight and the efficiency of NAC administration.

• Animal Bioscience
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• v.36 no.2
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• pp.218-228
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• 2023

Objective: This study investigated the effects of feeding anthocyanin-rich black cane treated with ferrous sulfate and molasses on animal performance, rumen fermentation, microbial composition, blood biochemical indices, and carcass characteristics in meat goats. Methods: Thirty-two Thai-native×Anglo-Nubian crossbred male goats (14.47±2.3 kg) were divided equally into two groups (n = 16) to investigate the effect of feeding diet containing 50% untreated anthocyanin-rich black cane silage (BS) vs diet containing anthocyaninrich black cane silage treated with 0.03% ferrous sulfate and 4% molasses (TBS) on average daily gain (ADG) and dry matter intake (DMI). At the end of 90 d feeding trial, the goats were slaughtered to determine blood biochemical indices, rumen fermentation, microbial composition, and carcass characteristics differences between the two dietary groups. Results: Goats fed the TBS diet had greater ADG and ADG to DMI ratio (p<0.05). TBS diet did not affect rumen fluid pH; however, goats in the TBS group had lower rumen ammonia N levels (p<0.05) and higher total volatile fatty acid concentrations (p<0.05). Goats in the TBS group had a higher (p<0.05) concentration of Ruminococcus albus but a lower (p<0.05) concentration of methanogenic bacteria. The TBS diet also resulted in lower (p<0.05) thiobarbituric acid-reactive substances concentration but higher (p<0.05) total antioxidant capacity, superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase concentrations in blood plasma, while having no effect on plasma protein, glucose, lipid, immunoglobin G, alanine transaminase, and aspartate aminotransferase. Meat from goats fed the TBS diet contained more intramuscular fat (p<0.05) and was more tender (p<0.05). Conclusion: In comparison to goats fed a diet containing 50% untreated anthocyanin-rich black cane silage, feeding a diet containing 50% anthocyanin-rich black cane silage treated with 0.03% ferrous sulfate and 4% molasses improved rumen fermentation and reduced oxidative stress, resulting in higher growth and more tender meat.