• Proceedings of the Materials Research Society of Korea Conference
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• 2003.03a
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• pp.94-94
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• 2003

최근, 새로운 전자재료로서 GaN 분말의 합성과 응용에 관한 연구가 많이 이루어지고 있다. CaN 분말은 열처리 과정 중 분해를 방지하기 위한 표면 보호용 소재, CaN 박막 또는 벌크 결정을 성장하기 위한 precursor 및 대면적 평판표시소자 제작을 위한 전기발광소자용 소재 등에 적용되고 있다. 일반적으로 100$0^{\circ}C$ 이상의 온도에서Ga과 NH$_3$를 반응시키거나, Ga이 포함된 화합물반도체 또는 산화물 및 질산염 등을 NH$_3$ 분위기에서 가열시켜 GaN 분말을 합성시키고 있다. 본 논문에서는 출발물질로서 GaOOH를 채택하고, 이를 NH$_3$ 가스를 흘리면서 가열 반응시켜 GaN 분말을 합성하고 X선 회절분석 방법을 사용하여 GaN의 합성에 대한 반응기구를 조사하였다. GaN 분말을 합성하기 위하여 GaOOH 분말 1g을 석영 용기에 담아 석영 반응관 내에 위치시키고, 반응관 내부를 $10^{-3}$ torr의 진공으로 배기한 후 $N_2$를 주입하면서 전기로의 온도를 1$0^{\circ}C$/min으로 승온시켰다. 반응온도는 300~l17$0^{\circ}C$의 범위에서 변화시켰고, 반응시간은 10분부터 24시간까지 변화시켰으며, NH$_3$의 유량은 300~700 sccm의 범위에서 변화시켰다. GaN의 반응역학을 조사하기 위하여 X선 회절도에서 특정 성분의 회절강도는 시료 내에 포함된 특정 성분의 량에 직접 비례한다고 가정하고, 2$\theta$=37$^{\circ}$부근에서 관찰되는 GaN의 (101)면에 의한 회절강도를 측정하고, 이를 GaN의 생성량으로 고려하였다.}C$로 소결 하였다. coating 결과 박리현상은 없었으나, 표면과 단면의 SEM분석결과 다소 porous한 박막층이 형성되었으며, Ca이온이 지지체로 permeation되는 현상이 발생하였다. 이와 같은 결과로부터 보다 치밀한 박막생성을 위해, slurry 제조조건을 변화시켰으며, Ca이온의 migration을 막기 위해 barrier layer를 이용하였다 완전 소결된 지지체는 가스투과도와 전기전도도측정을 통하여 특성을 평가하였다.였다.다.m이하의 NH$_3$ 가스를 검출할 수 있었다.기 화강암 관입 이전에 좌수향 전단 운동에 의해 부분적으로 재활성 되었으며, 후기 화강암의 관입 이후에 재차 우수향 전단운동으로 활성화 되었음을 알 수 있다. 이상의 결과를 종합하면 호남전단대는 쥬라기 중기에 발생한 광역적인 우수향의 연성전단운동이나, 운동 특성은 연속적이기 보다는 단속적으로 일어난 것으로 생각된다.리 폐 관류는 정맥주입 방법에 비해 고농도의 cisplatin 투여로 인한 다른 장기에서의 농도 증가 없이 폐 조직에 약 50배 정도의 고농도 cisplatin을 투여할 수 있었으며, 또한 분리 폐 관류 시 cisplatin에 의한 직접적 폐 독성은 발견되지 않았다이 낮았으나 통계학적 의의는 없었다[10.0%(4/40) : 8.2%(20/244), p>0.05]. 결론: 비디오흉강경술에서 재발을 낮추기 위해 수술시 폐야 전체를 관찰하여 존재하는 폐기포를 놓치지 않는 것이 중요하며, 폐기포를 확인하지 못한 경우와 이차성 자연기흉에 대해서는 흉막유착술에 더 세심한 주의가 필요하다는 것을 확인하였다. 비디오흉강경수술은 통증이 적고, 입원기간이 짧고, 사회로의 복귀가 빠르며, 고위험군에 적용할 수 있고, 무엇보다도 미용상의 이점이 크다는 면에서 자연기흉에 대해 유용한 치료방법임에는 틀림이 없으나 개흉술에 비

• Atmosphere
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• v.25 no.2
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• pp.295-308
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• 2015

Based on the CMIP5 historical simulation datasets, we assessed the performance of state-of-the-art climate models in respect to the relationship between interannual variabilities of the North Pacific synoptic eddy (NPSE) and East Asian winter monsoon (EAWM). Observation (ERA-Interim) shows a high negative correlation (-0.73) between the interannual variabilities of East Asian winter monsoon (EAWM) intensity and North Pacific synoptic eddy (NPSE) activity during the period of 1979~2005. Namely, a stronger (weaker) EAWM is related to a weaker (stronger) synoptic eddy activities over the North Pacific. This strong reverse relationship can be well explained by latitudinal distributions of the surface temperature anomalies over East Asian continent, which leads the variation of local baroclinicity and significantly weakens the baroclinic wave activities over the northern latitudes of $40^{\circ}N$. This feature is supported by the distribution of the meridional heat flux (${\overline{{\nu}^{\prime}{\theta}^{\prime}}}$) anomalies, which have negative (positive) values along the latitudes $40{\sim}50^{\circ}N$ for strong(weak) EAWM years. In this study, the historical simulations by 11 CMIP5 climate models (BCC-CSM1.1, CanESM2, GFDL-ESM2G, GFDL-ESM2M, HadGEM2-AO, HadGEM2-CC, IPSL-CM5A-LR, MPI-ESM-LR, MPI-ESM-MR, MRI-CGCM3, and NorESM1-M) are analyzed for DJF of 1979~2005. Correlation coefficient between the two phenomena is -0.59, which is comparable to that of observation. Model-to-model variation in this relationship is relatively large as the range of correlation coefficient is between -0.76 (HadGEM2-CC and HadGEM2-AO) and -0.33 (MRI-CGCM3). But, these reverse relationships are shown in all models without any exception. We found that the multi-model ensemble is qualitatively similar to the observation in reasoning (that is, latitudinal distribution of surface temperature anomalies, variation of local baroclinicity and meridional heat flux by synoptic eddies) of the reverse relationship. However, the uncertainty for weak EAWM is much larger than strong EAWM. In conclusion, we suggest that CMIP5 models as an ensemble have a good performance in the simulation of EAWM, NPSE, and their relationship.

• Parasites, Hosts and Diseases
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• v.55 no.2
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• pp.149-158
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• 2017

Variant surface antigens (VSAs) encoded by pir families are considered to be the key proteins used by many Plasmodium spp. to escape the host immune system by antigenic variation. This attribute of VSAs is a critical issue in the development of a novel vaccine. In this regard, a population genetic study of vir genes from Plasmodium vivax was performed in the Republic of Korea (ROK). Eighty-five venous blood samples and 4 of the vir genes, namely vir 27, vir 21, vir 12, and vir 4, were selected for study. The number of segregating sites (S), number of haplotypes (H), haplotype diversity (Hd), DNA diversity (${\pi}$ and ${\Theta}_w$), and Tajima's D test value were conducted. Phylogenetic trees of each gene were constructed. The vir 21 (S=143, H=22, Hd=0.827) was the most genetically diverse gene, and the vir 4 (S=6, H=4, Hd=0.556) was the opposite one. Tajima's D values for vir 27 (1.08530, P>0.1), vir 12 (2.89007, P<0.01), and vir 21 (0.40782, P>0.1) were positive, and that of vir 4 (-1.32162, P>0.1) was negative. All phylogenetic trees showed 2 clades with no particular branching according to the geographical differences and cluster. This study is the first survey on the vir genes in ROK, providing information on the genetic level. The sample sequences from vir 4 showed a clear difference to the Sal-1 reference gene sequence, whereas they were very similar to those from Indian isolates.

• Journal of Microbiology and Biotechnology
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• v.21 no.4
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• pp.366-373
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• 2011

We characterized the proteomes of murine N2a cells following infection with three rabies virus (RV) strains, characterized by distinct virulence phenotypes (i.e., virulent BD06, fixed CVS-11, and attenuated SRV9 strains), and identified 35 changes to protein expression using two-dimensional gel electrophoresis in whole-cell lysates. The annotated functions of these proteins are involved in various cytoskeletal, signal transduction, stress response, and metabolic processes. Specifically, a-enolase, prx-4, vimentin, cytokine-induced apoptosis inhibitor 1 (CIAPIN1) and prx-6 were significantly up-regulated, whereas Trx like-1 and galectin-1 were down-regulated following infection of N2a cells with all three rabies virus strains. However, comparing expressions of all 35 proteins affected between BD06-, CVS-11-, and SRV9-infected cells, specific changes in expression were also observed. The up-regulation of vimentin, CIAPIN1, prx-4, and 14-3-3 ${\theta}/{\delta}$, and down-regulation of NDPK-B and HSP-1 with CVS and SRV9 infection were ${\geq}2$ times greater than with BD06. Meanwhile, Zfp12 protein, splicing factor, and arginine/serine-rich 1 were unaltered in the cells infected with BD06 and CVS-11, but were up-regulated in the group infected with SRV9. The proteomic alterations described here may suggest that these changes to protein expression correlate with the rabies virus' adaptability and virulence in N2a cells, and hence provides new clues as to the response of N2a host cells to rabies virus infections, and may also aid in uncovering new pathways in these cells that are involved in rabies infections. Further characterization of the functions of the affected proteins may contribute to our understanding of the mechanisms of RV infection and pathogenesis.

• Science of Emotion and Sensibility
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• v.14 no.2
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• pp.311-320
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• 2011

To quantitatively analyze the effects of color stimulation which is one of the major affecting factors on human emotion, we studied the relationship between color preference and the Electroencephalography (EEG) to 3 color stimuli; bright yellow red (BYR), deep green yellow (DGY), and vivid blue (VB). Physiological signal measured by EEG on the color stimulation was closely related with their well-known colorful images. The brain become more activated with decreasing the color temperature (BYR${\geq}$DGY>VB), and the right brain is more sensitive than the left. On the whole, the EEG values of the frequency bands are in order to beta ${\geq}$ theta and alpha > gamma. As decreasing the color temperature, beta wave increased (BYR${\geq}$DGY>VB), and alpha, beta and gamma waves increased with increasing the color temperature (BYR${\geq}$DGY>VB). The relationship between the color preference and EEG values showed EEG gets more activated at some frequency bands when the color preference becomes higher. In conclusion, the specific frequency band could be activating by a color stimuli which had showed higher the preference. It means that these color stimuli can apply for various industries such as beauty industry, interior design, fashion design, color therapy, and etc.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.781-784
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• 2016

The Plurinational State of Bolivia (Bolivia) has a high incidence rate of gallbladder cancer (GBC). However, the genetic and environmental risk factors for GBC development are not well understood. We aimed to assess whether or not cytochrome P450 (CYP1A1), glutathione S-transferase mu 1 (GSTM1), theta 1 (GSTT1) and tumor suppressor protein p53 (TP53) genetic polymorphisms modulate GBC susceptibility in Bolivians. This case-control study covered 32 patients with GBC and 86 healthy subjects. GBC was diagnosed on the basis of histological analysis of tissues at the Instituto de Gastroenterologia Boliviano-Japones (IGBJ); the healthy subjects were members of the staff at the IGBJ. Distributions of the CYP1A1 rs1048943 and TP53 rs1042522 polymorphisms were assayed using PCR-restriction fragment length polymorphism assay. GSTM1 and GSTT1 deletion polymorphisms were detected by a multiplex PCR assay. The frequency of the GSTM1 null genotype was significantly higher in GBC patients than in the healthy subjects (odds ratio [OR], 2.35; 95% confidence interval [CI], 1.03-5.37; age-adjusted OR, 3.53; 95% CI, 1.29-9.66; age- and sex-adjusted OR, 3.40; 95% CI, 1.24-9.34). No significant differences were observed in the frequencies of CYP1A1, GSTT1, or TP53 polymorphisms between the two groups. The GSTM1 null genotype was associated with increased GBC risk in Bolivians. Additional studies with larger control and case populations are warranted to confirm the association between the GSTM1 deletion polymorphism and GBC risk suggested in the present study.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.255-261
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• 2014

Essential fatty acid (EFA) is known to be required for the body to function normally and healthily. However, the effect of EFA on glucose uptake in skeletal muscle has not yet been fully investigated. In this study, we examined the effect of two EFAs, linoleic acid (LA) and ${\alpha}$-linolenic acid (ALA), on glucose uptake of C2C12 skeletal muscle cells and investigated the mechanism underlying the stimulatory effect of polyunsaturated EFAs in comparison with monounsaturated oleic acid (OA). In palmitic acid (PA)-induced insulin resistant cells, the co-treatment of EFAs and OA with PA almost restored the PA-induced decrease in the basal and insulin-stimulated 2-NBDG (fluorescent D-glucose analogue) uptake, respectively. Two EFAs and OA significantly protected PA-induced suppression of insulin signaling, respectively, which was confirmed by the increased levels of Akt phosphorylation and serine/threonine kinases ($PKC{\theta}$ and JNK) dephosphorylation in the western blot analysis. In PA-untreated, control cells, the treatment of $500{\mu}M$ EFA significantly stimulated 2-NBDG uptake, whereas OA did not. Phosphorylation of AMP-activated protein kinase (AMPK) and one of its downstream molecules, acetyl-CoA carboxylase (ACC) was markedly induced by EFA, but not OA. In addition, EFA-stimulated 2-NBDG uptake was significantly inhibited by the pre-treatment of a specific AMPK inhibitor, adenine 9-${\beta}$-D-arabinofuranoside (araA). These data suggest that the restoration of suppressed insulin signaling at PA-induced insulin resistant condition and AMPK activation are involved at least in the stimulatory effect of EFA on glucose uptake in C2C12 skeletal muscle cells.

• Journal of Astronomy and Space Sciences
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• v.25 no.4
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• pp.383-394
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• 2008

We examine geoeffective directional parameters of coronal mass ejections (CMEs). We select 30 front-side halo CMEs from SOHO LASCO CMEs whose speed is larger than 1000km/s and longitude is less than ${\pm}30^{\circ}$. These are thought to be the most plausible candidate of geoeffective CMEs. We examine the relation between CMEs directional parameters (Earthward direction, eccentricity, ${\Delta}$ distance and central angle parameter) and the minimum value of the Dst index. We have found that the Earthward direction parameter has a good correlation with the Dst index, the eccentricity parameter has a much better correlation with the Dst index. The bo distance and central angle parameter has a poor correlation with the Dst index. It's, however, well correlated with the Dst index in very strong geomagnetic storms. Most of CMEs causing very strong storms (Dst ${\leq}$-200nT) are found to have large Earthward direction parameter $({\geq}0.6)$, small eccentricity, bo distance and central angle parameters $(E{\leq}0.4,\;{\Delta}X\;and\;sin\;{\theta}{\leq}0.2)$. These directional parameters are very important parameters that control the geoeffectiveness of very fast front-side halo CMEs.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2001.09a
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• pp.172-175
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• 2001

이 연구에서는 5개의 시추공에 대한 양수시험을 실시하여 대수층의 수리학적 이방성과 지하수의 주 유동방향을 규명하고자 하였다. 코아검층 및 초음파주사검층을 통해 각각의 공에 대한 균열방향을 결정하고 이를 토대로 통합해본 결과 크게 세 방향의 균열군이 집중성을 보였다. 가장 빈도가 높은 균열의 방향은 N0$^{\circ}$~40$^{\circ}$E/30$^{\circ}$~50$^{\circ}$SE 그리고 N30$^{\circ}$~ 80 $^{\circ}$W/20$^{\circ}$~50$^{\circ}$ NE이 방향이 함께 나타났으며 두 번째 균열의 방향은 N0$^{\circ}$ ~50$^{\circ}$E/60$^{\circ}$ ~80$^{\circ}$NW로 나타났다. 세 번째 방향은 N30$^{\circ}$~50 $^{\circ}$W/70$^{\circ}$~80$^{\circ}$SW방향의 균열로 구성된다. 이처럼 지표하에서는 크게 세 방향의 균열이 다른 방향을 보이는 균열에 비해 상대적으로 큰 빈도를 가지며 발달하고 있음을 알 수 있다. 대수층이 이방성이고 균질하다는 가정하에 양수시험을 실시하여 각각의 공에 대한 최대 투수량계수 ( $T_{{\varepsilon}{\varepsilon}}$)와 최소 투수량계수 ( $T_{ηη}$)값을 산출하고 주 텐서방향 ($\theta$)을 결정하였다. 그 결과 BH-1, BH-4, BH=5공을 제외한 BH-2, BH-3호공에서의 이방성 투수량계수텐서값은 이 논문의 가정인 대수층이 이방성이고 균질하다는 가정에 일치하지 않았다. 따라서 원형좌표계에 도시하였을 때 다른 공에 비해서 비균질성이 심한 결과로 인해 이방성타원체 에서 많이 벗어남을 보였다. 이로인해 3개의 공 BH-1, BH-4, BH-5호공을 사용하여 대수층의 이방성을 분석하여 보았다. BH-1호공에서의 $T_{{\varepsilon}{\varepsilon}}$는 171.90 $m^2$/day, $T_{ηη}$는 71.0l $m^2$/day이고 주 텐서방향은 Nl5.39$^{\circ}$ E로 나타났다. BH-4호공의 $T_{{\varepsilon}{\varepsilon}}$는 268.20 $m^2$/day, $T_{ηη}$는 28.75 $m^2$/day이고 주 텐서방향은 N7.55$^{\circ}$E이며 BH-5호공에서의 $T_{{\varepsilon}{\varepsilon}}$는 168.40 $m^2$/day, $T_{ηη}$는 66.80 $m^2$/day이고 주 텐서방향은 N76.59$^{\circ}$E로 나타났다. 이처럼 연구지역에서의 각각의 공에 대한 투수량계수텐서는 서로 다르게 나타났으며 이에 따른 주 텐서방향도 서로 다름을 알 수 있다.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.301-301
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• 2006

The physical properties of well-defined star-shape polystyrenes with high number of arms (6 to 57 arms) in good and theta solvents were studied using synchrotron X-ray scattering. The scattering profiles for multi-armed polystyrenes shown the molecular shape is changed according to increasing of number of arm. From various parameters which were obtained from scattering profiles, the molecular shape was determined more detail. As results, the molecular shape was changed from a fuzzy-ellipsoid for 6-armed PS to a fuzzy-sphere sphere for 57-armed PS according to increasing of number of arm.