• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.5778-5784
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• 2013

In order to develop anti-wrinkle agent, we measured the anti-oxidative activity of gallic acid (GA) from Paeonia suffruticosa Andrews and investigated its cytotoxicity in HaCaT cells and then investigated its effect on tumor necrosis factor alpha (TNF-${\alpha}$)-induced matrix metalloproteinase-1 (MMP-1) mRNA, protein expressions and secretion in same cells. GA showed anti-oxidative activity with $IC_{50}$ of 30 ${\mu}g/mL$ and its activity was higher than that of butylated hydroxyanisol (BHA). GA showed weak cytotoxicity with high concentration (200 ${\mu}g/mL$) in HaCaT cells. MMP-1 mRNA, protein expression and secretion induced by tumor necrosis factor alpha (TNF-${\alpha}$) in HaCaT cells were significantly decreased by treatment of GA with dose-dependent manner(p<0.05). Therefore, our findings suggest that GA can be useful as an active ingredient for cosmeceuticals of anti-wrinkle effects.

• Journal of Environmental Impact Assessment
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• v.8 no.1
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• pp.93-105
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• 1999

Lately water quality of Daechong Reservoir has become more eutrophicated than ever before and there has been much concern over especially the eutrophication of the embayment near Daejon and Chongju Water Intake Tower every summer. The purpose of this study is to predict the impact of change in the pollutant loading, flowrate, nitrogen and phosphorus release from sediment, SOD(sediment oxygen demand) upon the water quality of Daechong Reservoir by WASP5/EUTR05 in order to suggest water quality management alternatives. The data of Sep. 1995 were used for the calibration of the model and those of Sep. 1997 was for verification. The result of the modeling can be summarized as follows. 1. The 50% increase(decrease) of pollutant loading has caused that of T-N concentration by 0.10-0.14 mg/l, T-P concentration by 0.003-0.005 mg/l, and CBOD concentration by 0.16-0.18 mg/l. But the ratio of DO change by the change of pollutant loading was relatively small. 2. The sensitivity test of NH4 flux to T-N and that of P04 flux to T-P shows that T-N and T-P concentration were changed more in the epilimnion segments (SEG4, SEG5, SEG6, SEG7) than the other segments. As SOD increases, DO was predicted to decrease more especially in the hypolimnion (SEG9-SEG14). 3. As flowrate increase, the concentration of T-N, T-P, and CBOD were predicted to decrease, but DO concentration increased especially in the hypolimnion segments(SEG11, SEG12, SEG13, and SEG14). As the flowrate changed from $119m^3/sec$ to $50m^3/sec$, the concentration of T-N and CBOD in the hypolimnion was predicted to decrease.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.12C
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• pp.759-763
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• 2011

In this paper, a dual-band T-shaped microstrip monopole antenna with a pair of slits for 2.4/5.2/5.8-GHz wireless local area networks (WLANs) is proposed. A pair of T-shaped slits is loaded on a T-shaped monopole antenna fed by microstrip line in order to obtain dual-band operation as well as to reduce the antenna size. It is demonstrated from experimental results that the proposed antenna can cover all the required bands for WLAN. The measured impedance bandwidth for VSWR<2 is about 5.7% (2.37-2.51GHz) in the lower frequency band and about 28.8% (4.76-6.35GHz) in the higher frequency band. The measured peak gains are about 1.33 dBi to 1.66 dBi in the 2.4GHz band, 3.50 dBi to 3.95 dBi in the 5.25GHz band, and 2.06 dBi to 2.34 dBi in the 5.8GHz band.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1972.03a
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• pp.3.2-3
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• 1972

Recently the adenosinetriphosphates have massive highlight due to their high energy source for treat and maintained all the cell mechanism in the individual. When the A. T.P. release the terminal phosphate, produces about 8,000 calories instead of the 3,000 calories from common chemical bonds. The high energy-P bond enables the cell to accumulate a great amount of energy in a very small space and the keep it ready to be used as soon as it is needed. The presence of A.T.P. explains why some important cellular functions such as nerve conduction can go on for some time even with complete inhibition of respiration. In recent years the A.T.P. were used in many clinical field with good effects. In this report was used A.T.P. 20mg＋Vit $B_1$ 50mg＋20% Dextrose 20㏄ through intravenousely for E.N.T. neurologic patient, such as neurogenic hearing impairment, tinnitus, dizziness, soft palate paralysis. By the injection 40% of neurogenic hearing impairment patients were improved and 62% tinnitus patients were improved and all the soft palate paralysis patient were completely recovered.

• Korean Journal of Digital Imaging in Medicine
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• v.14 no.2
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• pp.57-61
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• 2012

To compare the accuracy of breath-hold magnetic resonance imaging sequences to establish the most effective superparamagnetic iron oxide-enhanced sequence for detection of hepatic metastases. A total of 100 patients(50men and 50women, mean age: 60years) with liver disease(including malignant and benign liver lesions) were investigated at 3.0T machine (GE, General Electric Medical System, Excite HD) with 8Ch body coil. Pulse sequence for MR imaging decided to the FS-T2-FSE-RT(TR/TE/Thick./Freq./Phase=12857ms/100ms/7mm/512/384), MGRE(TR/TE/Thick./Freq./Phase=100ms/9.7ms/7mm/384/288), in-out of phase echo(TR/$TE_1$, $TE_2$/Thick./Freq./Phase=140ms/2.4, 5.8ms/7mm/352/300), Images obtained before the injection of SPIO. Six sequences were optimized for lesion detection: FS-T2-FSE-RT, multigradient recalled echo data image(MGRE), T2-weighted MGRE with an 9.7msec echo time. Images were reviewed independently by five blinded observers. The accuracy of each sequence was measured by using picture archiving communication system analysis. All results were correlated with findings at multidectator computed tomography examination. Differences between the mean results of the six observers were measured by using paired student t-test analysis. Postcontrast T2-weighted MGRE sequences were the most accurate and were significantly superior to postcontrast FS-T2-FSE-RT, T2-weighted MGRE, in-out of phase MR sequences(p < .05). For all lesions that were malignant or smaller than 1 cm, respectively, contrast to noise ratio of pre and postcontrast sequences were -1and -0.3 for T2-weighted FSE, 0.53 and 4.5 in-out of phase, 7, 7.08, 5.08, 3.32, 1.7, 1.16, 0.79, 0.68 for GRE with 2.9, 7.5, 12.1, 16.6, 21.2, 25.8, 30.4, 35.0 TE values. Breath-hold various TE precontrast sequences offer improvement in sensitivity compared with fixed multigradient recalled echo sequences alone.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.168-170
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• 2022

The government enacted and promulgated the 'Severe Accident Punishment Act' in January 2021, and is enforcing the law for workplaces with 50 or more full-time workers. However, the number of industrial accident accidents in 2021 increased by 10.7% compared to the same period of the previous year, and chemical gas Safety accidents due to leaks and explosions also occur frequently. Therefore, in high-risk industrial sites, comprehensive Safety measures are urgently needed. In this study, BLE Mesh networking in industrial sites with poor communication environment apply technology. The complex sensor AIoT device recognizes a dangerous situation as a gas sensing value, voice, and motion value, and transmits it to the server. The server monitors the risk situation in real time through information value analysis and judgment through artificial intelligence LSTM algorithm and CNN algorithm for AIoT transmission information. Through this study, through the development of AIoT devices capable of gas sensing, voice and motion recognition, and AI-applied safety management systems, It will contribute to the expansion of the social safety net by expanding its application.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.115-129
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• 2007

Objectives : This study was carried out to evaluate anti-oxidative, anti-microbial and anti-cancer effect for clinical application of Bibangtalmyungsan (BTS) Results : 1. The oxidative effects were measured by polyphenol, DPPH radical scavenging activity. BTS water extract was showed more effective than ethanol extract and also various solvent fractions from BTS water extract showed effective in the following order : ethyl acetate fraction > butanol fraction > hexane fraction ${\fallingdotseq}$ chloroform fraction ${\fallingdotseq}$ aqueous fraction 2. The results of anti-microbial effects were as follows. 1) Antibacterial activities of BTS extracts against Gram's negative and positive bacteria were ineffective 2) Antifungal activities of the BTS extracts against Aspergillus spp. , Trichohyton mentagrophyte KTCC 1077 were not effective. 3. The result of anti-cancer effects were as followings: 1) BTS ethanol extract was more effective than water extract against Caco-2, Calu-6, but it had cytotoxic effect against NIH3T3. 2) On the Caco-2, effective only in ethyl acetate $fraction(IC_{50}:$ 35.81 ${\mu}g/ml)$. 3) On the Calu-6, the most effective in ethyl acetate $fraction(IC_{50}:$ 189.65 ${\mu}g/ml)$ and effective In butanol $fraction(IC_{50}:$ 299.74 ${\mu}g/ml)$ and hexane $fraction(IC_{50}:$ 345.13 ${\mu}g/ml)$ 4) On the SUN-601, $IC_{50}$ value was within 80 ${\mu}g/ml$ in ethyl acetate fraction and hexane fraction. 5) On the HCT-1l6, the most effective in ethyl acetate $fraction(IC_{50}:$ 82.94 ${\mu}g/ml)$ and effective in hexane $fraction(IC_{50}:$ 374.56 ${\mu}g/ml)$. 6) On the AML-2/WT, the most effective in ethyl acetate $fraction(IC_{50}:$ 41.44 ${\mu}g/ml)$ and effective In hexane $fraction(IC_{50}:$ 303.01 ${\mu}g/ml)$. 7) On the NIH3T3, effective only in ethyl acetate $fraction(IC_{50}:$ 203.42 ${\mu}g/ml)$, but it was more ineffective than other cancer cells. Conclusion : These result suggest that BTS has antioxidative, antifungal activities and cytotoxic effects against Caco-2, Calu-6, SUN-601, HCT-116, AML-2/WT and NIH3T3, especially ethyl acetate fraction from water extract has more effective in antioxidative and anticancer effects.

• Journal of Food Hygiene and Safety
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• v.36 no.1
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• pp.86-92
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• 2021

In order to utilize edible insect larvae as a functional material, the antioxidant components and activities of Tenebrio molitor larvae extracts were evaluated. The total phenolic content of the extract by ethanol concentration (95%, 70%, 50%, water) of T. molitor larvae powder was the highest in the 50% ethanol extract at 459.23 ± 1.05 mg%, and the total flavonoid content was the highest in the water extract at 19.86 ± 0.69 mg%. The DPPH radical scavenging activity of T. molitor larvae powder extract was the highest in 70% ethanol extract at 82.60 ± 0.00%, followed by water, 50% ethanol, and 95% ethanol extract. The ABTS radical scavenging activity in 50% ethanol and water extract was highest at 97.57 ± 0.16% and 95.33 ± 0.41%, respectively, with no significant difference. Significantly, the reducing power was the highest in water extracts, followed by 50%, 70%, and 95% ethanol extract. The results confirmed the antioxidant components and antioxidant activities of T. molitor larvae have been identified, indicating that it is worth using as a functional material.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.41 no.6
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• pp.687-693
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• 1992

To improve dielectric, piezoelectric and temperature stability in 0.50Pb(SnS11/2TSbS11/2T)OS13T - 0.35PbTiOS13T - 0.60PbZrOS13T + 0.4[wt%]MnOS12T piezoelectric ceramics which is used for surface acoustic wave devices, CrS12TOS13T was added and the specimens were fabricated by Hot Press method, and their characteristics were measured with CrS12TOS13T addition. From the results, in the specimen added by 0.2[wt%]CrS12TOS13T, dielectric constant and mechanical quality factor were 380 and 2307, respectively, and it was suited for surface acoustic wave device and the temperature coefficient of the resonant frequency in the specimen added by 0.4[wt%]CrS12TOS13T was the least value of 74.96[ppm/$^{\circ}C$].

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.3
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• pp.394-400
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• 2004

To investigate the efficacy of alternatives to antibiotics, the present study was conducted to compare the effects of antibiotic, lactic acid, a blend of commercial essential oils (EOs) and EOs in combination with lactic acid on growth performance and the functional activity of the gut in broiler chickens. A total of 168 broiler chickens were given the basal diet supplemented with 10 ppm colistin (T1), 0.1% lactic acid (T2), 25 ppm EOs (T3), 25 ppm EOs+0.1% lactic acid (T4), 50 ppm EOs (T5) or 50 ppm EOs+0.1% lactic acid (T6) in the period 3 to 35 days of age. As a result, the broiler chickens assigned to T4 group throughout the experimental period had apparently (p<0.05) greater body weight and total gain than these assigned to T1, T2, T3 and T5 groups. However, there was no difference in growth performance among the birds fed the diets supplemented with antibiotic (T1), lactic acid (T2) and EOs (T3 and T5) alone. The weights of digestive organs and the number of lactobacilli and E. coli in the lower ileum were not affected by dietary treatments. Total trypsin activity was significantly (p<0.05) greater in T4 than T1, T2, T3 and T5 groups. Total and specific pancreatic $\alpha$-amylase activities were significantly (p<0.05) enhanced in the broiler chickens fed T4 diet compared with these fed T1, T2 and T3 diets. However, there were no differences in growth performance and digestive enzyme activities including pancreatic trypsin and $\alpha$-amylase between T4 and T6 groups fed the diets supplemented with either low or high EOs levels in combination of lactic acid. In conclusion, a blend of commercial EOs combined with lactic acid showed significant increases in digestive enzyme activities of the pancreas and intestinal mucosa, leading to increase in growth performance.