• 대한두경부종양학회지
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• 제17권2호
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• pp.174-178
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• 2001

Background and Objective: Percutaneous ethanol injection therapy has been used in the treatment of the benign thyroid diseases. Although the reported side-effects of the therapy was mild and transient, some side-effects including local or radiating pain are troublesome to the patients. Radioactive iodine-131($Ra-^{131}I$) also has been effectively and safely used for management of the benign thyroid diseases. So we developed the percutaneous intranodular injection therapy of $Ra-^{131}I$ as an alternative of percutaneous ethanol injection therapy. Materials and Methods: From December 1998 to October 1999, we treated 29 outpatients (25 women and 4 men, mean age: $47{\pm}12$ years). Inclusion criteria were follows; age >30 years, cytologically benign, with normal thyroid function, cold nodule on thyroid scintigram, solid or mixed natured nodules in sonographical evaluation. Nodular volume was estimated by sonography according to the ellipsoid formula. $Ra-^{131}I$(0.1mCi/ml) was administered in a single dose injection. Follow-up studies every 3 months consisted of full history, thyroid function test, and sonography. We determined the therapeutic response is effective if the volume reduction of the nodule occurred above 30%. Results: After at least 3 months follow-up, 11 patients showed effective response, 12 patients showed minimal or unchanged response and 6 patients showed progression. Although side-effects such as injection pain, febrile reaction, and hormonal changes were absent, an infectious complication in injection site was developed from 1 case. Conclusion: Although we need a more prolonged follow-up to evaluate the delayed sequelae, we can suggest that percutaneous intranodular injection therapy of $Ra-^{131}I$ may be an attractive non-surgical treatment in selected cases of benign thyroid nodules.

• 대한두경부종양학회지
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• 제11권2호
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• pp.125-131
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• 1995

The authors present 15 cases in which the diagnosis of thyroid cancer was established pathologically among 300 cases of Graves' disease diagnosed clinically at Chosun University Hospital, from January 1982 to December 1994. These cases were analyzed in order to establish guidelines for prophylactic node dissection as part of the initial management of thyroid cancer in patients with Graves' disease. The analysis revealed the following: 1) The average age of the 15 patients was 34.5 years and the male: female ratio was 1 : 4.0. 2) In 8 of the 15 cases(53.5 %) the occult thyroid carcinoma measured less than 1.5cm. 3) The degree of invasivensess manifested in these fifteen cases may be summarized as follows: In Group 1(6 cases) there was absence of microscopic capsular invasion and of lymphnode metastasis. In Group 11(4 cases) threre was microscopic capsular invasion but absence of lymphnode metastasis: In Group III(4 cases) there was either extrathyrodal soft tissue invasion or regional lymph node metastasis: and in Group IV(1 case) there was lymphnode invasion and distant metastasis. 4) Thirteen patients underwent either subtotal or near total thyroidectomy, and 2 patients underwent total thyroidectomy. Seven patients underwent some type of neck dissection, as follows: anterior compartment dissection in one of the cases in Group I; functional neck dissection in two cases and jugular node dissection in one case in Group II; and anterior compartment dissection in one case and modified radical neck dissection in two cases in Group III. 5) The author propose the following guidelines for prophylactic initial node dissection when a unexpected coexisting thyroid carcinoma in encountered on the frozen section during the surgical management of Graves' disease; Group I cases do not require initial neck dissection in group II, anterior compartment dissection in sufficient. In Group III, either jugular node dissection or functional neck dissection should be performed, and followed by postoperative Ra$^{131}$I therapy, Group IV requires Ra$^{131}$I therapy with or without modified radical neck dissection depending in the patient's condition.

• 핵의학기술
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• 제13권3호
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• pp.48-55
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• 2009

목적 : 현재 원자력법에 환자의 입원치료, 외래치료의 기준 용량(mCi)과 선량률(${\mu}Sv/h$)이 명확히 고시되어 있지 않아, (IAEA, BSS)기준에 따라 환자를 퇴원시킨다. 그래서 $^{131}I$ 3700 MBq (100 mCi)를 투여하는 갑상선암 치료환자에게 입원기간 동안 선량률(${\mu}Sv/h$)을 측정하여 선량률(${\mu}Sv/h$)과 잔류량(mCi), 배설률(%)에 따라 $^{131}I$ 3700 MBq (100 mCi)가 70%가 감소하여 1110 MBq (30 mCi)가 되는 시간을 확인하여 치료환자들의 퇴원기준 설정에 참고 자료가 되고자 한다. 실험재료 및 방법 : 갑상선제거수술을 받고 $^{131}I$ 3700 MBq (100 mCi)을 투여하는 환자 중 신장 기능에 이상이 없는 42명을 대상으로 하였다. 측정기는 Thermo사의 FH40G-L을 사용하여 $^{131}I$ Capsule을 개봉하고서 $^{131}I$ 3700 MBq (100 mCi)을 투여 후 즉시부터, 거리와 높이 1m에서 1, 2, 4, 8, 20, 24, 40시간째 소변 전/후 20초간 평균 측정하였다. 결과 및 결론 : (IAEA, BSS) 기준에 따라 $^{131}I$ 3700 MBq (100 mCi)를 투여한 후 20시간째 $49{\pm}13\;{\mu}Sv/h$로 100%에서 78%가 배설하여 체내에 814 MBq (30 mCi)가 잔류하여 퇴원 가능한 체내 잔류량 1110 MBq (30 mCi) (1 m에서 $66\;{\mu}Sv$/h) 이하를 만족하였다.

• Journal of Periodontal and Implant Science
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• 제28권2호
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• pp.337-350
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• 1998

The purpose of this' study was to compare surface roughness and morphologic changes after use of various plaque control devices to titanium implant surfaces. The study materials were 6 ITI titanium implants($Bonefit^{(R)}$) and 5 plaque control devices. 6 implants were divided into 6 different groups and instrumented by each plaque control devices as follows. 1) Group I : untreated control 2) Group II : Titanium curette(Titanium $curette^{(R)}$, 3i) 80 vertical/horizontal strokes 3) Group III : Plastic curette($Implacare^{(R)}$, Hu-Friedy) 80 vertical/horizontal strokes 4) Group N : Plastic tip-ultrasonic scaler($Amdent^{(R)}$, Amdent) 160 seconds 5) Group V : Rotating interdental brush($Identobrush^{(R)}$, Identoflex) 160 seconds 6) Group VI : Abrasive rubber cup polisher($Zircate^{(R)}$, Prophy paste, Dentsply) 160 sec-onds. All specimens were prepared for evaluation by surface roughness tester, optical stereomicroscopy(OM) and scanning electron microscopy(SEM). The Ra and Rt mean values of the tested specimens were 1) Group I ($Ra=0.170{\pm}0.007{\mu}m$, $Rt=1.297{\pm}0.016{\mu}m$) 2) Group II ($Ra=0.209{\pm}0.006{\mu}m$, $Rt=1.602{\pm}0.110{\mu}m$) 3) Group III ($Ra=0.179{\pm}0.001{\mu}m$, $Rt=1.429{\pm}0.055{\mu}m$) 4) Group IV ($Ra=0.182{\pm}0.005{\mu}m$, $Rt=1.511{\pm}0.085{\mu}m$) 5) Group V ($Ra=0.301{\pm}0.008{\mu}m$, $Rt=1.882{\pm}0.131{\mu}m$) 6) Group VI ($Ra=0.147{\pm}0.010{\mu}m$, $Rt=1.059{\pm}0.021{\mu}m$) In Ra values, experimental group II, V, VI were statistically significant different when compared with control. OM and SEM observation showed that experimental group III, IV were minimal changes when compared with control and group VI was smoothest among other experimental groups. The results suggested that plastic curette and plastic tip-ultrasonic scaler were predictable devices to titanium implant surface.

• 한국환경복원기술학회지
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• 제16권1호
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• pp.131-145
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• 2013

The purposes of this research are : to analyze biotop type and carry out conservation value assessment in study areas, Daegu Science Park national industrial complex; to supply basic data for the landscape ecological planning; and to improve the application of assessment model with the development of Biotop Value Assessment Tool (B-VAT). The result is as follows. First of all, the field survey showed 434 species of flora and 220 species of insecta. According to the result of biotop type analysis in the biotop classification system with field survey, 13 biotope groups and 63 biotope types were classified. In the map of biotop type classification, readjusted farmland biotop(FA) was prevalent and forest biotop(E) was shown to the southeast side of the site. Next, according to the first assessment with B-VAT, total 19 biotop types including natural river(BA) with abundant plants had I grade and total 16 biotop types such as vegetable garden adjacent to river(BC) had V grade. In terms of the second assessment, we analyzed total 30 areas, total 82 areas, respectively, which had special meaning for the conservation of species and biotop(1a, 1b) and which had meaning for the conservation of species and biotop(2a, 2b, 2c). This research will be a basic data, which can solve the damage problem systematically and control it landscape-friendly with biotop classification and assessment which we developed. In particular, we expect that biotop value assessment tool(B-VAT) with GIS will be a great contribution to popularity compared with the value model by complicated algorism such as adding-matrix, weight and equal distribution. In addition, this will save the time and improve the accuracy for hand-counting.

• 한국식품위생안전성학회지
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• 제36권3호
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• pp.248-256
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• 2021

건조 수산가공식품의 안전성 확보를 위해 2020년 경기도 내 유통 중인 건조 수산가공식품 12품목 120건을 수거하여 방사능(¹³¹I, ¹³⁴Cs, ¹³⁷Cs) 및 중금속(납, 카드뮴, 비소, 수은) 함량을 분석하였다. 모든 시료에서 자연 방사성 핵종 중 하나인 ⁴⁰K만 검출되었으며, 인공 방사성 물질인 ¹³¹I, ¹³⁴Cs, ¹³⁷Cs는 최소검출가능농도(MDA) 이하의 값을 나타내었다. 중금속의 평균 함량[평균±표준편차(최소값-최대값)]은 생물로 환산하였을 때 납 0.066±0.065(N.D.-0.332) mg/kg, 카드뮴 0.200±0.406(N.D.-2.941) mg/kg, 비소 3.630±3.170(0.371-15.007) mg/kg, 수은 0.009±0.011(0.0005-0.0621) mg/kg 이었으며, 수산물에서 중금속 기준이 있는 제품의 경우 모두 기준 규격 이내로 나타났다. 국내산 제품과 수입산 제품의 중금속 함량은, 조개의 카드뮴과 새우의 수은 함량에서만 유의적인 차이를 나타내었다(P<0.05). 본 연구 결과, 유통 중인 건조 수산가공식품에서 방사능 및 중금속은 안전한 수준인 것으로 판단되나, 식품 중 특히 수산물에서 방사능 오염에 대한 국민의 우려가 크기 때문에 국민들의 불안감 해소를 위해 방사능 검사는 지속적으로 필요할 것으로 생각된다. 또 향후 건조 수산가공식품 중에서도 건조된 형태로 직접 섭취 가능한 제품의 중금속 관리 기준 설정을 위한 기초 자료로 활용할 수 있을 것이다.

• 한국실내디자인학회논문집
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• 제18권4호
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• pp.124-131
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• 2009

The aesthetics of current dermatology clinics are the main space of dermatology, which is gradually becoming an area of specialty. Paths requiring spatial transition due to the expansion of treatment field in dermatology clinics are currently emerging, meaning that the duty to provide medical and aesthetic environment with high spatial connection must be accompanied. Contrary to past clinics where only functional aspects were emphasized, current clinics require a differentiated environment that considers both aspects of function and aesthetics, centered on the patient. The purpose of this research in this perspective is to study the efficient connection between dermatology and aesthetics, while also analyzing identity factors to indicate design factors differentiated from other functional spaces, to apply them as preliminary data for the planning of dermatology clinics. Based on the above, six dermatology clinics located in Seoul were designated for case studies through field studies. Overall, Aesthetics connected to dermatology clinics legally must have separate business registrations and have alternative entrance ways. Currently however, there were many cases where entrance, waiting, reception and receipt were not separated. there were efforts to partially display identities when analyzing design factors that formed the identity of dermatology clinics. However, there were insufficient cases where visual communication factors such as a clinic's spatial identity, logo, signing system, and applied products were integrated into a coherent theme. At this point when dermatology clinics are becoming brands, all fields must merge for integrated identity effects that go beyond the boundaries of contemporary H.I, to clearly display their identity with the clinics' professional image and consistent concept.

• 한국해양학회지:바다
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• 제19권2호
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• pp.131-146
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• 2014

남해대륙붕 가막만의 현생퇴적층 음향특성과 분포양상을 조사하기 위해 고해상도 탄성파 자료와 퇴적물을 분석하였다. 표층퇴적물의 입도는 주로 $6.3{\sim}9.7{\Phi}$의 분포를 보인다. 퇴적물은 니질과 실트로 구성되어 있으며, 내만으로 갈수록 입도가 감소한다. 고해상도 탄성파 자료에서 나타나는 가막만의 층서는 하부 경계면인 음향기반암 위로 2개의 퇴적층서(GB I과 II)로 구성되며 이들 층서는 중간 반사 경계면(최대해침면)에 의해 구분된다. 매우 불규칙한 형태를 보이는 음향기반암은 일반적으로 해수면 아래 약 20 m에서부터 최대 40 m 깊이에서 나타나며, 남쪽으로 갈수록 깊어진다. 하부층인 GB I은 수로를 피복하는 형태로 발달하고 있으며 무층리 반사 특징을 보인다. 이는 후기 해침동안 퇴적된 해침퇴적계열(TST)로, 조간대환경 퇴적층으로 해석할 수 있다. 최대해침면은 평균 해수면 아래 약 15 m에서부터 28 m 깊이에서 나타나며, 탄성파 단면상에서 편평하고 연속적인 반사면으로 나타난다. 최대해침면 위에 놓여있는 GB II는 투명 혹은 반투명한 음향특성, 그리고 평행한 반사 층리로 구성되며, 해수면이 현재의 위치에 도달했던 지난 6,000년 이후에 퇴적된 고해수면 퇴적계열(HST)로 해석된다. 특히, GB II 퇴적층은 고해수면 반사 경계면에 의해 2개의 층(GB II-a and II-b)으로 세분화되며 이는 바람, 해수 유동량, 그리고 조류에 의해 구분된 것으로 생각된다.

• Ocean and Polar Research
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• 제31권1호
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• pp.121-131
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• 2009

In an effort to better understand the physiological and ecological differences between warm and cold water copepod species in Korean waters using lipid contents and compositions, two species of copepods (Pleuromamma sp. as a warm water species and Neocalanus plumchrus as a cold water species) were collected from the Northwest Pacific and East Sea/Sea of Japan, respectively. The cold water species showed two fold higher lipid contents than the warm water species (11% vs. 5% of dry weight). Wax esters, known as one of the major storage lipid classes, were found to be the dominant lipid class (accounting for 64% of total lipids) in the cold water species, whereas, in the warm water species, phospholipids, which are known as membrane components, were the dominant lipid class (accounting for 43% of total lipids),with a trace amount of the storage lipids as a form of triacylglycerols (${\leq}1%$ of total lipids). With regard to the fatty acid compositions, saturated fatty acids (SAFA), especially 16:0 (about 30% of total fatty acids), were most abundant in the warm water species, whereas the polyunsaturated fatty acids (PUFA), particularly eicosapentaenoic acid (EPA : 20:5(n-3)) (${\geq}16%$ of total fatty acids), were most abundant in the cold water species. Among the neutral fraction of lipids, phytol, originating from the side chain of chlorophyll and indicative of active feeding on phytoplankton, was detected only in the warm water species. Significant quantities of fatty alcohols were detected in cold water species, particularly long-chain monounsaturated fatty alcohols (i.e. 20:1(n-9) and 22:1(n-11)), which are well known to abound in cold water herbivorous copepods. However, only trace amounts of short-chain fatty alcohols were detected in the warm water species. Twelve different kinds of sterols were detected in these copepod species, with cholest-5-en-$3{\beta}$-ol (cholesterol) and cholesta-5, 24-dien-$3{\beta}$-ol (desmosterol) dominating in cold and warm water species, respectively. In addition, for the warm water species (Pleuromamma sp.), we assessed the latitudinal gradients of lipid contents and compositions using samples from three different latitudinal regions (Philippine EEZ, Japan EEZ, and the East China Sea). Although no latitudinal gradients of lipid contents were detected, the lipid compositions, particularly dietary fatty acid markers, varied significantly with the latitude. The findings of this study confirm that the distribution of lipid contents and compositions in copepods may not only indicate their nutritional condition and diet history, but may also provide insights into their living strategies under different environmental conditions (i.e., water temperature, food availability).