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Antimicrobial Activity of the Monoterpenes of Pinus Plants on Escherichia coli and Aspergillus nidulans (소나무과 식물이 지닌 Monoterpenes가 Escherichia coli와 Aspergillus nidulans의 성장저해에 미치는 영향)

  • 이은주;김종희
    • The Korean Journal of Ecology
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    • v.25 no.5
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    • pp.353-358
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    • 2002
  • We examined the effect of 12 main monoterpenes in Pinus plants on growth inhibition of Escherichia coli and Aspergillus nidulans. We tested four concentrations of each compound by comparing the clear zone with controls. (R)-(-)carvone, (S)(+)carvone, (1R)(-)fenchone, (-)menthone, α-pinene, (1S) (-)verbenone and (+)β - pinene had a inhibition effect on E. coli. (R)-(-)carvone, (S)(+)carvone, (+) β-pinene, geranyl-acetate, α-pinene, and (1S)(-)verbenone had inhibitory effects on the growth of A. nidulans. Geranyl-acetate inhibit growth of A. nidulans, however not to E. coli. And (1R)(-)fenchone and (-)menthone inhibit growth of E. coli, but not to A. nidulans. Myrcene, sabinene, bornyl acetate, and limonene had no inhibitory effects on E. coli and A. nidulans, eventhough at the highest concentration. All these results suggested that some selected monoterpenes had antifungal activities depend on the species of microorganism.

Studies on the Controlled Release Fertilizer METAP Application on Paddy Rice (1972) (수도에 대한 완효성비료 METAP의 비효시험(1972))

  • Lee, E.W.;Ahn, S.B.;Lee, M.H.;Lee, Z.Y.;Song, N.H.;Kwon, S.M.;Kim, C.Y.;Choe, B.C.;Chung, H.S.;Cho, B.O.;Lee, I.J.;Park, C.S.;Ko, C.S.;Park, K.H.;Chung, S.C.;Chung, H.S.;Lee, H.D.;Park, S.T.;Lee, H.S.;Choe, S.R.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.13
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    • pp.107-118
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    • 1973
  • Experiments were carried out to study the effectiveness of METAP as a slow released fertilizer on the growth, grain yield and its components of paddy rice, and to compare its effects with those of single fertilizers in the fields of 3 Crop Experiment Stations and 7 provincial Offices of Rural Development. The effectiveness of METAP seems to be different according to the physical and chemical characteristics of soil, the time of application, climatic conditions, variety and cultural methods. Therefore, the experimental results obtained from the above experiment are summurized as follows: 1. When METAP was applied into sandy soil, grain yield was increased due to increase of the number of panicles, and split application of METAP was more effective than basal only. However, in the reclaimed soil, not heavily percolated soil and fertile soil, no differences were observed between MET AP and single fertilizer applied plot. 2. When a rice variety, 'TONGIL' which is sensitive to the low temperature and produce higher yield in the early transplanting, was not transplanted early and air temperature is relatively lower during the ripening stage, the percentage of ripened grains and 1,000 grains weight were not higher in the METAP applied plots than in the single fertilizer applied plots.

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A Study on the Effect of Direct Government R&D Funding on SMEs: A Comparative Analysis between SMEs and Large Companies (정부의 중소기업에 대한 연구개발투자 효과: 대기업과의 비교분석을 통하여)

  • Oh, Yunjung;Yong, Tae-Seok
    • Journal of Technology Innovation
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    • v.22 no.3
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    • pp.37-63
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    • 2014
  • This study is intended to demonstrate how different factors induce the Korean government's direct investment in research and development according to the type of business enterprise in Korea. We analyzed that what factors made the government directly invest in research and development by using a total of 18,272 company panel data, which are not limited to specific industries or government-led research and development (R&D) programs. The results showed that the direct investment for R&D by the government led to the increase in the number of researchers in SMEs. For major companies, the direct investment resulted in the increase of sales and company's own R&D expenses. Moreover, this study found that government's direct support for R&D even led to the decrease of SMEs' own R&D expenses; however, this result was not statistically significant. In addition, the most significant factor to increase both SMEs' and major company's own R&D expenses was the sales amount of the company, rather than government's direct investment for R&D. The factor that increases sales was the company's own R&D expenses, rather than government's direct investment for R&D. Through the analysis using Mixed Effects Model, this study suggested the policy should be changed to make SMEs invest in its own R&D expenses, rather than to secure researchers of SMEs by government's direct investment for R&D.

Detection of Cleavage Sites on 5S rRNA by Methidiumpropyl-EDTA-Iron(II)

  • Kim, Sang-Bumn;Cho, Bong-Rae;Lee, Young-Hoon;Park, In-Won
    • BMB Reports
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    • v.29 no.2
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    • pp.133-136
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    • 1996
  • The affinity cleavage reagent Methidiumpropyl-EDTA-Iron(II) is applied to the structural analysis of 5S rRNA. Analysis of cleavage sites induced by MPE-Fe(II) on 5S rRNA shows that MPE intercalates easily between the unstable base pairs or into the bulges, thereby it strongly cuts the nucleosides nearby. The stable helical stems A, B, D and E as well as loop d are weakly cut. Most of the single-stranded loops are not cleaved. Based on the cleavage pattern of the 5S rRNA by MPE-Fe(II) and RNase V1, we suggest that MPE-Fe(II) may be used as a potential chemical probe in searching for the unstable helical regions of RNA, and for the sequences that appear to be involved in folding and distorting 5S rRNA.

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S-R Variation and Antimicrobial Susceptibility of Escherichia coli Isolated from Mastitic Cows, Diarrheal Pigs and Diarrheal Chickens (젖소유방염, 돼지 및 닭의 설사중에서 분리한 대장균의 S-R 변이와 항균 요법제의 감수성)

  • 정희곤
    • Journal of Environmental Health Sciences
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    • v.23 no.3
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    • pp.50-55
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    • 1997
  • 1992년부터 1995년까지 약 4개년 동안 전남 지역에서 사육하고 있는 가축의 유병률을 조사한 결과, 유방염으로 의심이 되는 젖소 970두 중에서 180두(18.6%)가 유방염에 이환되었으며, 돼지 2,400두 중에서 84두(3.5%)가 설사증에 이환되었고, 닭 1,010수중에서 9수(0.9%)가 설사증에 이환되었다. 대장균의 분리율을 조사한결과, 유방염에 이환되어 있는 젖소 180두중 37두(20.6%)에서 대장균이 분리되었으며, 설사증에 이환되어 있는 돼지 84두중 51두(60.7%)에서 대장균이 분리되었고, 설사증에 이환되어 있는 닭 9수중 5수(55.6%)에서 대장균이 분리되었다. Acriflavine을 이용하여 대장균의 S-R변이를 조사한 결과, S-R변이는 mercuric chloride, cysteine, caffeine, glucose, nicotine 등의 순으로 나타났는데, 이중 mercuric chloride가 가장 감수성이 높았다. 대장균의 항균요법제에 대한 감수성은 naxcel, linsmycin, cephalexin, gentamycin등이 높은 감수성을 나타내었는데, S-R변이 후에는 감수성이 일반적으로 저하되는 경향이었다.

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