• Clinical and Experimental Pediatrics
• /
• v.59 no.sup1
• /
• pp.19-24
• /
• 2016

Constitutional interstitial deletions of the long arm of chromosome 5 (5q) are quite rare, and the corresponding phenotype is not yet clearly delineated. Severe mental retardation has been described in most patients who present 5q deletions. Specifically, the interstitial deletion of chromosome 5q33.3q35.1, an extremely rare chromosomal aberration, is characterized by mental retardation, developmental delay, and facial dysmorphism. Although the severity of mental retardation varies across cases, it is the most common feature described in patients who present the 5q33.3q35.1 deletion. Here, we report a case of a de novo deletion of 5q33.3q35.1, 46,XY,del(5)(q33.3q35.1) in an 11-year-old boy with mental retardation; to the best of our knowledge this is the first case in Korea to be reported. He was diagnosed with severe mental retardation, developmental delay, facial dysmorphisms, dental anomalies, and epilepsy. Chromosomal microarray analysis using the comparative genomic hybridization array method revealed a 16-Mb-long deletion of 5q33. 3q35.1(156,409,412-172,584,708)x1. Understanding this deletion may help draw a rough phenotypic map of 5q and correlate the phenotypes with specific chromosomal regions. The 5q33.3q35.1 deletion is a rare condition; however, accurate diagnosis of the associated mental retardation is important to ensure proper genetic counseling and to guide patients as part of long-term management.

• Journal of the Korean earth science society
• /
• v.22 no.6
• /
• pp.500-511
• /
• 2001

For the southeastern Korea aound the Yangsan fault we measured Q$_P^{-1}$ and Q$_S^{-1}$ simultaneously by using the extended coda-normalization method for seismograms registered at 9 stations deployed by KIGAM. We analyzed 707 seismograms of local earthquakes that occurred between December 1994 and February 2000. From seismograms, bandpass filtered traces were made by applying Butterworth filter with frequency-bands of 1${\sim}$2, 2${\sim}$4, 4${\sim}$8, 8${\sim}$16 and 16${\sim}$32 Hz. Estimated Q$_P^{-1}$ and Q$_S^{-1}$ values decrease from (7${\pm}$2)${\times}$10$^{-3}$ and (5${\pm}$4)${\times}$10$^{-4}$ at 1.5 Hz to (5${\pm}$4)${\times}$10$^{-3}$ and (5${\pm}$2)${\times}$10$^{-4}$ at 24 Hz, respectively. By fitting a power-law frequency dependent to estimated values over the whole stations, we obtained 0.009 (${\pm}$0.003)f$^{-1.05({\pm}0.14)$ for Q$_P^{-1}$ and 0.004 (${\pm}$0.001)f$^{-0.75({\pm}0.14)$) for Q$_S^{-1}$, where f is frequency in Hz.

• Journal of the Korean Mathematical Society
• /
• v.46 no.4
• /
• pp.733-746
• /
• 2009

For any integer k $\geq$ 2, let P(c, k + 1;q) be the number of all k+1-tuples with positive integer coordinates ($a_1,a_2,...,a_{k+1}$) such that $1{\leq}a_i{\leq}q$, ($a_i,q$) = 1, $a_1a_2...a_{k+1}{\equiv}$ c (mod q) and 2 $\nmid$ ($a_1+a_2+...+a_{k+1}$), and E(c, k+1; q) = P(c, k+1;q) - $\frac{{\phi}^k(q)}{2}$. The main purpose of this paper is using the properties of Gauss sums, primitive characters and the mean value theorems of Dirichlet L-functions to study the hybrid mean value of the r-th hyper-Kloosterman sums Kl(h,k+1,r;q) and E(c,k+1;q), and give an interesting mean value formula.

• Tuberculosis and Respiratory Diseases
• /
• v.58 no.5
• /
• pp.490-497
• /
• 2005

Background : The paraoxonase enzyme plays a significant role in the detoxification of various organophosphorous compounds in mammals, and paraoxonase (PON) 1 is one of the endogenous free-radical scavenging systems in the human body. In this study, we investigated the interaction between cigarette smoking and the genetic polymorphism of PON1 with lung cancer in Korean males. Methods : Three hundred thirty five patients with lung cancer and an equal number of age-matched controls were enrolled in this study. Every subject was asked to complete a questionnaire concerning their smoking habits and alcohol drinking habits. A 5' exonuclease assay (TaqMan) was used to genotype the PON1 Q192R polymorphism. The effects of smoking habits and drinking habits, the PON1 Q192R polymorphism and their interactions were statistically analyzed. Results : Cigarette smoking and the Q/Q genotype of PON1 were significant risk factors for lung cancer. Individuals carrying the Q/Q genotype of PON1 were at a higher risk for lung cancer as compared with those individuals carrying the Q/R or R/R genotype (odds ratio, 2.84; 95% confidence interval, 1.69 - 4.79). When the groups were further stratified by the smoking status, the Q/Q PON1 was associated with lung cancer among the current or ex-smokers (odds ratio, 2.56; 95% confidence interval, 1.52 - 4.31). Current smokers or ex-smokers who had the Q/Q genotype showed an elevated risk for lung cancer (odds ratio: 15.50, 95% confidence interval: 6.76 - 35.54) as compared with the group of subjects who never smoked, and had the Q/R or R/R genotype. The odds ratios (95% confidence interval) of smokers with the PON1 Q/Q type compared to the nonsmokers with the PON1 Q/R or R/R type were 53.77 (6.55 - 441.14) for squamous cell carcinoma, 6.25 (1.38 - 28.32) for adenocarcinoma, and 59.94 (4.66 - 770.39) for small cell carcinoma, and these results were statistically significant. Conclusion : These results suggest that cigarette smoking and the PON1 Q/Q genotype are risk factors for lung cancer. The combination of cigarette smoking and the PON1 Q/Q genotype significantly increased the lung cancer risk irrespective of the histologic type of cancer.

• Journal of the Korean Geophysical Society
• /
• v.3 no.3
• /
• pp.193-200
• /
• 2000

The attenuation characteristics($Q^{-1}$) are important factors representing the physical properties of the Earth interiors, and are essential for the quantitative prediction of strong ground-motion. Based on 156 earthquakes including 76 single-station record on the seismic station located Deok-jung Ri, southeastern Korea, we made the simultaneous measurement of P and S wave attenuation($Q_P^{-1}\;and\;Q_S^{-1}$) by means of extended coda-normalization method. Estimated $Q_P^{-1}\;and\;Q_S^{-1}$ decreased from $1{\times}10^{-2}\;and\;9{\times}10^{-3}$ at 1.5 Hz to $6{\times}10^{-4}\;and\;5{\times}10^{-4}$ at 24 Hz, respectively. This can be expressed by $Q_P^{-1}=0.01\;f^{-1.07}\;and\;Q_S^{-1}=0.01\;f^{-1.03}$ which indicate strong frequency dependence.

• Journal of the Chungcheong Mathematical Society
• /
• v.27 no.1
• /
• pp.1-8
• /
• 2014

Recently, q-Dedekind-type sums related to q-Euler polynomials was studied by Kim in [T. Kim, Note on q-Dedekind-type sums related to q-Euler polynomials, Glasgow Math. J. 54 (2012), 121-125]. It is aim of this paper to consider a p-adic continuous function for an odd prime to inside a p-adic q-analogue of the higher order Dedekind-type sums with weight related to modified q-Euler polynomials with weight by using Kim's p-adic q-integral.

• Proceedings of the Korean Society for Information Management Conference
• /
• 1995.08a
• /
• pp.37-40
• /
• 1995

본 연구는 자연언어시스템에서 색인어와 탐색어의 특정성에 기인하는 재현율 감소를 극복하기 위한 방법론으로써 탐색어의 확장을 통한 검색효율을 평가하였다. 이를 위하여 우리말 데이터베이스를 대상으로 주제전문가가 자연언어로 작성한 원 질의문 (Q1), 원 질의문에 사용된 탐색어와 데이터베이스내의 색인어간의 유사도를 이용하여 탐색어를 확장한 질의문 (Q2(0.2), Q2(0.3)), 주제전문가인 이용자가 Q1의 의미적인 관계를 고려해서 자연언어로 탐색어를 확장한 질의문 (Q3)을 검색효율면에서 비교하였다. 실험결과, 평균재현율은 Q2(0.2), Q2(0.3), Q3, Q1의 검색의 순이었다. 평균정확율은 Q3, Q2(0.3), Q1, Q2(0.2)검색의 순으로 나타났다.

• Journal of the Korean earth science society
• /
• v.28 no.6
• /
• pp.720-732
• /
• 2007

For the Seoul metropolitan area and the eastern Kyeongsang Basin, we simultaneously calculated $Q_P^{-1}$ and $Q_S^{-1}$ by applying the extended coda-normalization method for 98 seismograms of local Earthquakes. As frequency increases from 1.5 Hz to 24 Hz, the result decreased from $(4.0{\pm}9.2){\times}10^{-3}$ to $(4.1{\pm}4.2){\times}10^{-4}$ for $Q_P^{-1}$ and $(5.5{\pm}5.6){\times}10^{-3}$ to $(3.4{\pm}1.3){\times}10^{-4}$ for $Q_S^{-1}$ in Seoul Metropolitan Area. The result of eastern Kyeongsang basin also decreased from $(5.4{\pm}8.8){\times}10^{-3}$ to $(3.7{\pm}3.4){\times}10^{-4}$ for $Q_P^{-1}$ and $(5.7{\pm}4.2){\times}10^{-3}$ to $(3.5{\pm}1.6){\times}10^{-4}$ for $Q_S^{-1}$. If we fit a frequency-dependent power law to the data, the best fits of $Q_P^{-1}$ and $Q_S^{-1}$ are $0.005f^{-0.89}$ and $0.004f^{-0.88}$ in Seoul metropolitan Area, respectively. The value of $Q_P^{-1}$ and $Q_S^{-1}$ in the eastern Kyeongsang basin are $0.007f^{-1.02}$ and $0.006f^{-0.99}$, respectively. The $Q_S^{-1}$ value of the eastern Kyeongsang basin is almost similar to Seoul metropolitan area. But the $Q_P^{-1}$ value of the eastern Kyeongsang basin is a little higher than that of Seoul metropolitan area. This may be that the crustal characteristics of the eastern Kyeongsang basin is seismologically more heterogeneous. However, these $Q_P^{-1}$ values in Korea belong to the range of seismically stable regions all over the world.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.19 no.2
• /
• pp.203-209
• /
• 2019

We will be establish the new $q(1{\leq}q{\leq}p-1)$ stores of firm $F_B$ to gain pop/(p+q) over rival firm $F_A$ that has already operate with p stores in a city of population pop. Han proposes inclusion-exclusion algorithm(IEA) that searches maximal pop top 5 location and select the maximum location take account of locate variation with increasing of $q=1,2,{\cdots},p-1$. This paper reduced the orignal graph into partial graph initially and search only q=1 node continually reduced in accordance with increasing $q=1,2,{\cdots},p-1$. If the final result is shown in the case of steel customer between q, the q locations farther separate in order to improve of solution. For the eleven experimental data, this algorithm is a relative simplicity and more optimal solution than Han's IEA.

• Korean Chemical Engineering Research
• /
• v.54 no.1
• /
• pp.101-107
• /
• 2016

This paper investigates the feasibility of applying the jet loop reactor for the neutralization of alkaline wastewater using carbon dioxide ($CO_2$). In this study, pH changes and $CO_2$ removal characteristics were examined by changing influent flow rate of alkaline wastewater (initial pH=10.1) and influent $CO_2$ flow rates. Influent flow rates of alkaline wastewater ($Q_{L,in}$) ranged between 0.9 and 6.6 L/min, and inlet gas flow rate ($Q_{G,in}$) of 1 and 6 L/min in a lab-scale continuous flow jet loop reactor. The outlet pH of wastewater was maintained at 7.2 when the ratio ($Q_{L,in}/Q_{G,in}$) of $Q_{L,in}$ and $Q_{G,in}$ was 1.1. However, the $CO_2$ removal efficiency and the outlet pH of wastewater were increased when $Q_{L,in}/Q_{G,in}$ ratio was higher than 1.1. Throughout the experiments, the maximum $CO_2$ removal efficiency and the outlet pH of wastewater were 98.06% and 8.43 at the condition when $Q_{G,in}$ and $Q_{L,in}$ were 2 L/min and 4 L/min, respectively.