• 제목/요약/키워드: $P_2$-property

검색결과 1,579건 처리시간 0.036초

Lactobacillus casei Secreting ${\alpha}$-MSH Induces the Therapeutic Effect on DSS-Induced Acute Colitis in Balb/c Mice

  • Yoon, Sun-Woo;Lee, Chul-Ho;Kim, Jeong-Yoon;Kim, Jie-Youn;Sung, Moon-Hee;Poo, Har-Young
    • Journal of Microbiology and Biotechnology
    • /
    • 제18권12호
    • /
    • pp.1975-1983
    • /
    • 2008
  • The neuropeptide ${\alpha}$-melanocyte-stimulating hormone (${\alpha}$-MSH) has anti-inflammatory property by down regulating the expressions of proinflammatory cytokines. Because ${\alpha}$-MSH elicits the anti-inflammatory effect in various inflammatory disease models, we examined the therapeutic effect of oral administration of recombinant Lactobacillus casei, which secretes ${\alpha}$-MSH (L. casei-${\alpha}$-MSH), on dextran sulfate sodium (DSS)-induced colitis in Balb/c mice. Thus, we constructed the ${\alpha}$-MSH-secreting Lactobacillus casei by the basic plasmid, pLUAT-ss, which was composed of a PldhUTLS promoter and ${\alpha}$-amylase signal sequence from Streptococcus bovis strain. Acute colitis was induced by oral administration of 5% DSS in drinking water for 7 days. To investigate the effect of L. casei-${\alpha}$-MSH on the colitis, L. casei or L. casei-${\alpha}$-MSH was orally administered for 7 days and their effects on body weight, mortality rate, cytokine production, and tissue myeloperoxidase (MPO) activity were observed. Administration of L. casei-${\alpha}$-MSH reduced the symptom of acute colitis as assessed by body weight loss (DSS alone: $14.45{\pm}0.2\;g$; L. casei-${\alpha}$-MSH: $18.2{\pm}0.12\;g$), colitis score (DSS alone: $3.6{\pm}0.4$; L. casei-${\alpha}$-MSH: $1.4{\pm}0.6$), MPO activity (DSS alone: $42.7{\pm}4.5\;U/g$; L. casei-${\alpha}$-MSH: $10.25{\pm}0.5\;U/g$), survival rate, and histological damage compared with the DSS alone mice. L. casei-${\alpha}$-MSH-administered entire colon showed reduced in vitro production of proinflammatory cytokines and $NF-{\kappa}B$ activation. The ${\alpha}$-MSH-secreting recombinant L. casei showed significant anti-inflammatory effects in the murine model of acute colitis and suggests a potential therapeutic role for this agent in clinical inflammatory bowel diseases.

A Study for Recoverability of Iron Resource in Red Mud (레드머드 내 철 자원 회수 가능성 고찰)

  • Kim, Bong-Ju;Kwon, Jang-Soon;Koh, Yong-Kwon;Park, Cheon-Young
    • Economic and Environmental Geology
    • /
    • 제53권3호
    • /
    • pp.297-306
    • /
    • 2020
  • The red mud generated from bauxite during the Bayer alumina production process has been regarded as an industrial waste due to the high alkaline property and high content of Na. Despite of its environmental problem, various studies for recovery of the valuable resources from red mud has been also carried out because of high content (25.7 wt.% as Fe2O3 in this study) of iron in red mud. In order to recover the iron resource in the red mud, microwave heating experiments were performed with adding of activated carbon and elemental sulfur to the red mud. Through the microwave heating the powdered red mud mixtures converted to porous and vitrified solid aggregates. The vitrified aggregates produced by microwave heating are composed of goethite, zero valent iron (Fe0), pyrrhotite and pyrite. And then, the microwave heating samples were dissolved in the aqua regia solution, and Fe precipitates were obtained as a Fe-chlorides by adding of NaCl salt in the aqua regia solution. The Fe recovery rates in the Fe-chloride precipitates showed differences depending on the experimental mixture conditions, and Fe grades of the end products are 49.0 wt.%, 58.0 wt.% and 59.5 wt.% under mixture conditions of red mud, red mud + activated carbon, and red mud + activated carbon + elemental S, respectively. The Fe content of 56.0 wt.% is generally known as the grade value of Fe in a iron ore for iron production, and the Fe grades of microwave heating samples with adding activated carbon and elemental S in this study are higher than the grade value of 56.0 wt.%.

An Experimental Study on the Influence of High Quality Fly ash and Water-Binder Ratio on Properties of the Ternary System Concrete (3성분계 콘크리트의 특성에 미치는 고품질 플라이애쉬의 치환율 및 물-결합재비 영향에 관한 실험적 연구)

  • Lee, Seung-Min;Kim, Dong-Sool;Rho, Hyoung-Nam;Jung, Yong;Lee, Sang-Soo;Song, Ha-Young
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
    • /
    • pp.877-880
    • /
    • 2008
  • Recently the press and institute recognized fly ash as it had excellent performance. Its research and applications are on the rise largely as a substitute for cement. On the contrary, it is in a situation that the regulation of high quality fly ash remains at a low level. Accordingly, this study was to establish 8000 class of fineness of fly ash and three levels of substitute like 15%, 3 0%, and 45% in order to analyze the replacement ratio and effect of water-binder ratio for fly ash that affected the properties of ternary system concrete. As a result of experiment by planning water-binder ratio for two levels like 40% and 50%, it increased the fluidity in a fresh state, and it decreased the air content. This study has found out the setting acceleration and reduction of heat of hydration. As for the strength property in a set state, this study has shown the tendency of being equal or higher in age 28 days.

  • PDF

Red Pepper Productivity and Soil Properties as Affected by Different Intervals of Side-dressing N and K Applications in Plastic Film House

  • Ahn, Byung-Koo;Im, Ga-Young;Kim, Kab-Cheol;Chon, Hyong-Gwon;Jeong, Seong-Soo;Lee, Jin-Ho
    • Korean Journal of Soil Science and Fertilizer
    • /
    • 제47권3호
    • /
    • pp.147-154
    • /
    • 2014
  • Consecutive pepper cultivation in plastic film houses may lead to salt accumulation because pepper is considered a heavy nutrient feeder. For this reason, appropriate methods of fertilizer application should be established. Thus, we investigated the effect of different intervals of side-dressing N and K fertilizer applications on soil and red pepper in a plastic film house. All the amounts of recommended compost and phosphorus fertilizer were applied as basal dressing. Cultivars of the pepper plant were Cheon-Ha-Dae-Se (CHDS) and NW-BiGaLim (NW-BGL). Nitrogen and potassium fertilizers were treated as side-dressing at different intervals, 22 times in every 10 days, 15 times in every 15 days, and 11 times in every 20 days. Soil pH decreased with decreasing the intervals of side-dressing applications, whereas electrical conductivity (EC) declined with the increasing fertilizer application intervals. In particular, EC value decreased by up to 75% with CHDS cultivar in the plot of 20 day-interval and with NW-BGL cultivar in the plot of 15 day-interval. The concentrations of available phosphorus in the soils increased with increasing the interval. The concentration of exchangeable $K^+$ increased but exchangeable $Ca^{2+}$ and $Mg^{2+}$ decreased in all the plots, except in the control plot. The concentrations of nitrogen and phosphorus in leaves of the pepper plants were lowest in the control plot. Potassium concentrations in the pepper leaves were high in the control plot and in the plots of CHDS with 10 day-interval and NW-BGL with 15 day-interval. Red pepper productivity was high in the plots of 10- and 15 day-intervals for CHDS cultivar and 15- and 20 day-intervals for NW-BGL cultivar. Therefore, the 15 day-interval of side-dressing N and K applications was considered as an appropriate method for cultivating pepper plants and protecting soil in plastic film houses.

Controll over the Au@Ag Core-shell Nanoparticle 2D Patterns via Diblock Copolymer Inverse Micelle Templates and Investigation of the Surface Plasmon Based Optical Property (이중블록공중합체 역마이셀 주형을 이용한 Au@Ag 코어-쉘 나노입자 2차원 패턴 제어 및 표면 플라즈몬 기반 광학적 특성 연구)

  • Yoon, Min Ji;Kim, Jihyeon;Jang, Yoon Hee;Lee, Ji-Eun;Chung, Kyungwha;Quan, Li Na;Kim, Dong Ha
    • Journal of the Korean Chemical Society
    • /
    • 제57권5호
    • /
    • pp.618-624
    • /
    • 2013
  • We demonstrated unique inter- and intra-plasmonic coupling effects in bimetallic Au@Ag core-shell NP arrays which are regularly or randomly arranged on self-assembled block copolymer (BCP) inverse micelle monolayers. Polyvinylpyrrolidone (PVP)-stabilized Au@Ag core-shell NP arrays in regular or disordered configuration were incorporated and assembled on reconstructed PS-b-P4VP inverse micelle templates through two types of processes. The intensively enhanced LSPR coupling properties of individual and assembled Au@Ag NPs were evaluated by UV-visible spectroscopy in terms of the type of ligand stabilizer, coupling between Au and Ag, thickness of Ag shell, and type of array configuration. Finally, Au@Ag core-shell NP arrays were employed as active substrates for surface enhanced Raman spectroscopy (SERS) and a significantly enhanced signal enhancement was observed in accordance with the coupling intensity of Au@Ag NPs patterns.

Correlation between the Factors of Soil Physical Property in Upland Soil (밭작물 토양물리성 지표관련 인자의 상관분석)

  • Kim, Chan-Yong;Seo, Young-Jin;Kwon, Tae-Young;Park, Jun-Hong;Heo, Min-Soon;Ha, Sang-Keun
    • Korean Journal of Soil Science and Fertilizer
    • /
    • 제43권6호
    • /
    • pp.793-797
    • /
    • 2010
  • The investigations were conducted to improve the physical properties by analyzing physico-chemical properties on the different soil families of textures at 20 upland fields located in the parts of Gyengsangbuk-do area. Soil physico-chemical properties were analyzed for bulk density, hardness, porosity, moisture, pH, EC and organic mater by soil depth on the different soil families of textures. Bulk density distributions were higher than 1.2 Mg $m^{-3}$ in the optimum range. Hardness distributions were lower than 20 mm in the optimum range. Therefore, the physical properties of upland soil was deteriorated. Correlation coefficient of bulk density with hardness and organic mater were higher significantly, that was positive and negative, respectively. The soil hardness had the greatest distribution degree to the crop yield and bulk density and organic matter followed. Conclusively, To improve the physical properties of upland soil was more effective to fertilizing organic matter than other ways.

Analysis of Surface Contaminants and Physical Properties of the Daejanggakgibi Stele of Silleuksa Temple using Non-destructive Technology (비파괴 기술을 활용한 여주 신륵사 대장각기비의 표면오염물 분석과 물성진단)

  • KIM, Jiyoung;LEE, Myeongseong
    • Korean Journal of Heritage: History & Science
    • /
    • 제55권2호
    • /
    • pp.186-197
    • /
    • 2022
  • The Daejanggakgibi Stele of Silleuksa Temple in Yeoju is a stone stele from the Goryeo Dynasty that is inscribed with various stories about the construction of Daejanggak, a place where Buddhist scriptures were kept. This stele has been maintained for a long time in a state in which discoloration of the body has occurred, and the inscription has been partially damaged due to dozens of cracks. Using non-destructive analysis methods for stone artifacts, material investigation, portable X-ray fluorescence analysis, and ultrasonic velocity analysis for the stele were performed. It was confirmed that the stele body was composed of light gray crystalline limestone, and the base stone, support stone, and cover stone were medium-grained biotite granite. Portable X-ray fluorescence analysis confirmed that iron(Fe) was an original coloring element of the stele surface. From the distribution pattern of the coloration, it can be inferred that iron-containing materials flew down from between the stele body and the cover stone. Thereafter, living organisms or organic contaminants attached to it so that yellow and black contaminants were formed. Ultrasonic diagnosis revealed that the physical property of both the front and back surfaces ranged from fresh rocks(FR) to completely weathered rocks(CW), and the average weathering index was grade 3(intermediate). However, the point where cracks developed intensively was judged to be the completely weathered stage(CW), and some cracks located in the upper and lower parts of the stele bear potentially very high risk. It is necessary to monitor the movement of these cracks and establish reinforcement measures for conservation in the future.

Application of Hot Air for Shelf-Life Extension of Peach(Prunus persica L. Batsch) (열풍 처리 복숭아의 저장 중 품질 변화)

  • Lee, Kyung-Haeng;Park, Jae-Hee;Lee, Yu-Jin;Ban, Ki-Eun;Jang, Hyun-Jung;Choi, Ji-Hye
    • The Korean Journal of Food And Nutrition
    • /
    • 제26권4호
    • /
    • pp.731-736
    • /
    • 2013
  • To improve their shelf-life, domestic peaches were treated with hot air($46^{\circ}C$) for 0~9 hour, and the spoilage rate, changes of physico-chemical and sensory properties were investigated. The control showed spoilage at day 4, and then 50% of control showed spoilage on day 6. However, 12.5% of samples treated with hot air($46^{\circ}C$) for 6 hr showed spoilage on day 4. After 6 days, the spoilage rates of peaches treated with hot air treated for 3~9 hr were 16.7, 25.0, and 25.0%, respectively. Weight change of control was higher than that of hot air-treated samples for 6 days storage. There were no differences in pH of samples among the treatments, but pH increased with storage time. Hardness of hot air-treated samples was higher than that of control in the initial stage of storage. And then hardness of control sample was decreased faster than that of the hot air-treated samples for 6 days of storage. No significant changes in lightness and redness of the samples were observed after hot air treatment. Changes in yellowness of control occurred faster than that of hot air-treated samples during storage. The sensory parameters including taste, flavor, color, texture and overall acceptance at initial period were not different among treatments. The scores for taste, flavor, texture and overall acceptance of control decreased faster than those of hot airtreated samples during storage.

Cultural Characteristics of Rhizoctonia cerealis Isolated from Diseased Wheat Fields and Evaluation of the Resistance of Korean Winter Cereal Crops (밀 잎집눈무늬병원균(Rhizoctonia cerealis)의 배양적 특성과 국내육성 맥류 품종의 저항성 평가)

  • Lee, Eun-Sook;Lee, Wang-Hyu;Kang, Chun-Sik;Kim, Mi-Jung;Kim, Tae-Soo;Park, Jong-Chul
    • Research in Plant Disease
    • /
    • 제17권1호
    • /
    • pp.19-24
    • /
    • 2011
  • It was identified as a sharp eyespot (Rhizoctonia cerealis) that the isolates from abnormal symptoms in wheat that showed yellowing leaves, necrotic spot on stem base and dead tillers. These isolates have slower growth property and fewer mycelia than Rhizoctonia solani AG-1(1A) (KACC 40106). They showed binuclear cell, same media cultural and DNA characteristics to R. cerealis. They caused same symptoms on leaves and stem base appeared in artificial inoculation test, comparing to diseased wheat fields and also affect to maturing of kernels. They have optimal growth temperature and acidity on the artificial media as $20{\sim}25^{\circ}C$ and pH 5~7, respectively. In the investigation of varietal resistance of Korean winter cereal crops to sharp eyespot, there was no resistant in wheat cultivars that all materials infected over 20% diseased ratio. 12 cultivars including 'Anbaekmil', however, considered to moderate resistance with 20 to 30% infection ratio. The others crops using in feeding, whole crop barley, oat, rye and triticale were resistant below 15% diseased degree except the rye that showed over 50% infection rate. It was the first evaluation to sharp eyespot resistance for the Korean feeding crop cultivars. Most tested Korean barley cultivars for malting and food were moderate and susceptible to the sharp eyespot. Only 3 hulled barley, 'Tapgolbori', 'Albori' and 'Seodunchalbori', showed resistance with less than 10% diseased ratio. All tested naked barley cultivars showed susceptible response to the disease.

Study on the Effects of an Organic Fertilizer (Glutamic Acid Fermentation Residue Amended with N) on the Yield of Chinese Cabbage and Radish and the Physico-Chemical Properties of Soil (유기질비료(有機質肥料) 시용(施用)이 배추와 무우의 생육(生育)과 수량(收量) 및 토양(土壤)의 이화학성(理化學性)에 미치는 영향(影響))

  • Lim, S.U.;Ryu, J.C.;Hong, C.W.
    • Korean Journal of Soil Science and Fertilizer
    • /
    • 제12권3호
    • /
    • pp.125-132
    • /
    • 1979
  • A field experiment was conducted to evaluate the effectiveness of an organic fertilizer (Glutamic acid fermentation by product ameded with nitrogen) on the growth and yield of radish and chinese cabbage on a relatively fertile soil. Additional laboratory studies were also made to find out the influence of mentioned fertilizer on the phisical and chemical characteristic of soils. The results are summarized as following. 1. Effect of fertilizer on the growth and yield. a. On a relatively fertile soil with high organic matter content (3%), the organic fertilizer was not effective for the growth and yield of radish and yield of radish and chinese cabbage. b. The application of organic fertilizer increased the K contents in plants both in radish and chinese cabbage. It was observed that the high content of K in radish leave lowered the leaf/root ratio and the leaf/root ratio showed a positive correlation with root weight. 2. Effect on soil physical and chemical properties. a. The application of organic fertilizer resulted in the improvement of soil physical property by lowering bulk density and increasing porosity. b. It was found that application of organic fertilizer increased the water stable soil aggregates. c. The application of organic fertilizer did not result in the significant increase in soil organic matter. d. Soil pH was lowered by the application of organic matter. It was speculated that the oxidation of ammonical nitrogen in the fertilizer is responsible for the lowering of soil pH.

  • PDF