• Title/Summary/Keyword: $L_{eq}$

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Predictors of Health-related Quality of Life (HRQoL) in the Home-dwelling Disabled Persons by using EQ-5D: Results from the 3rd Korea National Health and Nutritional Examination Survey 2005 (재가 장애인의 EQ-5D를 활용한 건강관련 삶의 질의 영향 요인: 국민건강영양조사 제 3기(2005) 자료를 토대로)

  • Chung, Sung-Suk;Joung, Kyoung-Hwa
    • Korean Journal of Adult Nursing
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    • v.22 no.3
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    • pp.291-302
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    • 2010
  • Purpose: This study was a secondary data analysis aimed at identifying the predictors of health-related quality of life (HRQoL) of the home-dwelling disabled person by using EQ-5D which is a standardized instrument used as a measure of health outcome. Methods: Data were drawn from the 3rd Korea National Health and Nutritional Examination Survey conducted by the Ministry of Health and Welfare (MOHW). Subjects were 1,021 home-dwelling disabled persons over 19 years of age. Data were analyzed by using descriptive statistics, t-test, Pearson's correlation, one-way ANOVA, Scheff$\acute{e}$ test, and Stepwise multiple regression. Results: HRQoL (Health Related Quality of Life) is differentiated within age, genders, educational level, employment status, economic status, types and grades of disability, health problems associated with limited mobility, and the limited duration of time. HRQoL is correlated with age, number of cohabiters, educational level, grades of disability, activities of daily living (ADL), and instrumental ADL (IADL). HRQoL is significantly associated with ADL, health problems in connection with limited mobility, employment status, types of disability, marital status, grades of disability, and the limited duration of time. These factors explained 63.7% of variance in HRQoL. Conclusion: HRQoL among the disabled is related to their characteristics, ADL, and IADL. For this reason, it is necessary to develop health programs to promote those variables required to improve HRQoL.

A Rare Case of Hyponatremia Caused by Reset Osmostat in a Neonate with Cleft Lip, Cleft Palate, and Imperforate Anus

  • Ahn, Jung Gu;Lee, Jeong Eun;Chung, Woo Yeong;Koo, Soo Hyun;Shin, Jaeho;Jeon, Ga Won
    • Neonatal Medicine
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    • v.25 no.3
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    • pp.131-135
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    • 2018
  • Hyponatremia is defined as a plasma sodium concentration of <135 mEq/L. It is a common electrolyte imbalance in newborns. We report the case of a term neonate with cleft lip, cleft palate, imperforate anus, normal male karyotype, and chronic hyponatremia. On the 4th day of life, he showed hyponatremia (plasma sodium concentration 130 mEq/L) with low serum osmolality (275 mOsm/kg), high urine sodium (116.7 mEq/L), and high urine osmolality (412 mOsm/kg). His thyroid and adrenal functions were normal. Despite intravenous and oral sodium supplementation and hydrocortisone treatment, hyponatremia persisted. Brain magnetic resonance imaging showed normal results. He was diagnosed as having reset osmostat, a rare subtype of the syndrome of inappropriate secretion of antidiuretic hormone characterized by a subnormal threshold for antidiuretic hormone secretion, with hypotonic hyponatremia.

Effects of Potassium Ion Concentrations on the Cardiac Performances in the Turtle Heart Amyda japonica (자라 심장 박출량과 $K^{+}$ 농도)

  • Kim, Jun;Nam, Kee-Yong
    • The Korean Journal of Physiology
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    • v.14 no.1
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    • pp.31-39
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    • 1980
  • Changes in cardiac performances were observed under variations of the arterial and/or venous pressures with K-loading or K-depletion in turtle heart. Hearts were perfused with turtle Ringer-Locke's solutions containing various levels of potassium ion concentration. When venous pressure increased from 4 to 12 cm $H_2O$, cardiac output increased from $6.2{\pm}0.68$ to $15.7{\pm}0.75\;ml/min$, concomittantly. On the contrary, cardiac output decreased during the elevation of arterial pressure. Stroke work increased more prominently during the arterial pressure elevation than during the elevation of venous pressure. During K-depletion$(1{\sim}2mEq/L)$, cardiac output increased to two times that of normal K-concentration$(3{\sim}6\;mEq/L)$ group. Heart rate increased also, but less markedly. In K-loaded$(7{\sim}8\;mEq/L)$ group, both the cardiac output and heart rate decreased but stroke volume rather increased, because heart rate decrement was disproportionate to that of cardiac output. We concluded that in perfused turtle heart, cardiac output variation was more sensitive to K_depletion whereas heart rate to K-loading.

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Serum and CSF Mineral Profile of Himalayan Yak (Bas grunniens) in their Natural Habitat

  • Singh, S.P.;Kumar, N.;Sharma, K.B.;Kumar, R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.2
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    • pp.189-191
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    • 1999
  • Mineral profile of serum and cerebrospinal fluid (CSF) of 15 Himalayan Yak (adult female, n=8; adult male n=4 and young male,n=3) was studied in their natural habitat at an altitude of 3300 meters above mean sea level at Sangla in north western Himalayas. The macro and micro minerals estimated in serum and CSF were; Sodium, Potassium, Calcium and Magnesium and Zinc, Copper and Iron respectively. The values recorded among different Yak groups did not significantly differ from each other except serum iron and haemoglobin which were significantly higher (p<0.05 ) in young male Yaks compared to the adult male and female Yaks. An observation of great significance was considerably higher potassium and lower sodium level in Yaks compared to other bovine species of plains. The serum potassium values in some adult female Yaks were recorded as high as 10.4 mEq/l and the values varied between 6.6 to 9.8 mEq/l in young male Yaks. The serum Sodium values and Na:K ratios in Yak serum ranged between 117.5 to 122.6 mEq/l and 13.7 to 15.3 respectively. The possible relationship of high serum Potassium value with hypoxic conditions and hostile mountain environment has been discussed.

Inhibitory Effects of Ethanol Extracts from Polygoni multiflori radix and Cynanchi wilfordii radix on Melanogenesis in Melanoma Cells (하수오와 백하수오의 에탄올 추출물에 의한 B16/F10 Melanoma 세포주의 멜라닌 생성 억제효과)

  • Seo, Hee;Seo, Geun-Young;Ko, Su-Zie;Park, Young-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.8
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    • pp.1086-1091
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    • 2011
  • Anti-oxidative activity and tyrosinase inhibitory activity of various ethanol extracts of Polygoni multiflori radix (PMR) and Cynanchi wilfordii radix (CWR) were compared to identify an anti-oxidant and whitening agent source from nature. We conducted an investigation into the anti-oxidant activities of PMR and CWR ethanol extracts by measuring total polyphenol content, total flavonoid content, and ABTS radical capacity. The total polyphenol contents of PMR and CWR were 17.31${\pm}$0.54 mg GA/eq g, and 2.75${\pm}$0.22 mg GA/eq g, respectively. The total flavonoid contents of PMR and CWR were 6.38${\pm}$0.39 mg naringine/eq g, and 1.34${\pm}$0.09 mg naringine/eq g, respectively. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) radical decolorization of PMR and CWR were 96.89${\pm}$0.21% at 1 mg/mL and 93.49${\pm}$0.76% at 50 mg/mL. Melanoma cells were cultured with the PMR and CWR ethanol extracts for 48 hr, and total melanin content as a final product and the activity of tyrosinase, a key enzyme, in melanogenesis, were estimated. The PMR and CWR ethanol extracts increased melanin content and tyrosinase activity in a dose-dependent manner. These results suggest that PMR and CWR ethanol extracts could be useful as a skin whitening agent.

A Study on the Evaluation Method of Aircraft Noise (국내 항공기 소음 평가방법에 관한 실험적 연구)

  • Lee, Tai-Kang;Song, Kook-Gon;Kim, Hang;Jang, Gil-Soo;Kim, Sun-Woo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.11a
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    • pp.421-424
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    • 2007
  • Currently domestic criteria for the aircraft noise is being adapted WECPNL(weighted equivalent continuous perceived noise level), while internationally preferred method is $L_{dn}$ which is based on from $L_{eq}$ and can also evaluate environmental noise. WECPNL used in domestic as an evaluation metric is only for the aircraft noise. It is, therefore, not adequate for the evaluation of residents' injury, moreover, it is very difficult to measure the aircraft noise by WECPNL due to the complicated calculating procedures as long as automatic measuring system is not used. Accordingly, this study aims to propose alternative evaluation metric for the aircraft noise. To achieve this purpose, WECPNL, $L_{eq}$, $L_{dn}$, other metrics and criteria were compared and analyzed.

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Comparative Study on Growth and Yield of Far Eastern Catfish Silurus asotus and Leafy Vegetables Grown in Hybrid BFT-Aquaponics, Semi-RAS and Hydroponics (메기(Silurus asotus) 및 엽채류의 성장과 생산을 위한 Hybrid BFT 아쿠아포닉스(HBFT-AP), 반순환 양식(Semi-RAS) 및 수경재배(Hydroponics)의 비교 연구)

  • Lee, Dong-Hoon;Kim, Jin-Young;Lim, Seong-Ryul;Kim, Dal-Young;Kim, Kwang-Bae;Kim, Joo-Min;Kim, Jeong-Dae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.5
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    • pp.482-495
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    • 2019
  • This study compared the productivity of fish and vegetables grown using the hybrid biofloc technology-aquaponics (HBFT-AP), a semi-recirculating aquaculture system (SRAS), and hydroponics (HP). For the study of fish productivity (HBFT-AP vs. SRAS), fish were provided feed containing 3.0% monobasic potassium phosphate (MKP) for 18 weeks. After the 18-week feeding trial, the average weight of the sampled population (n=100) was not significantly different (P>0.05), while hematocrit (PCV, %), hemoglobin (Hb, g/dL), and plasma K (mEq/L) were significantly different (P<0.05) between the two groups (HBFT-AP: 47.83%, 15.48 g/dL, and 1.39 mEq/L; SRAS 34.83%, 11.81 g/dL, and 2.48 mEq/L). Leaf vegetable productivity (HBFT-AP vs. HP) was compared in three experiments (EXP 1-3), and slower growth was observed in both groups in EXP 2, in which pH was maintained at 5.0 or less throughout the experiment. During the 18-week feeding trial, total ammonia nitrogen (TAN), $NO_3-N$, and $PO_4-P$ levels increased with time in the HBFT-AP system, while the concentration of $NO_2-N$ remained below 0.1 mg/L throughout the study.

AN EXPERIMENTAL STUDY ON FAT CELL VIABLITY ACCORDING TO DIFFERENT HARVESTING TECHNIQUES (지방 채취 방법에 따른 지방 세포의 생존성에 대한 연구)

  • Lee, Won-Deok;Choi, Jin-Young
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.1
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    • pp.22-29
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    • 2008
  • Purpose: The purpose of this study is to test the efficacy of various methods of fat harvesting in animal model by viability comparison with assay including cell counting, MTT assay, and histologic evaluation. Materials and methods: New Zealand white rabbits experiments were used. Groin fat pads were subjected to different harvest method varying ingredients of solution(Experiment 1: T1 solution= lidocaine 1000mg/L, epinephrine 1mg/L, sodium bicarbonate 10mgEq/L, Triamcinolone 10mgEq/L; T2 solution=lidocaine 1000mg/L, epinephrine 1mg/L, sodium bicarbonate 0mgEq/L, Triamcinolone 0mgEq/L) and pressure exerted on harvesting with Luer-Lock syringe connected to suction cannula.(Experiment 2: P1 group=3cc intermittent pressure; P2 group=10cc sustained pressure) Fat cell viability was assessed with cell counting with a hemocytometer, MTT assay, and histologic evaluation. Results: Experiment 1 Cell count: T1=2.4/3.4/4.2, T2=9.6/8.4/7.2($\times10^5$ per mL); MTT assay: T1=0.516/0.41/0.453/0.412/0.421, T2=0.925/0.765/0.54/0.634/0.614 in 21 days(absorbance); Histology: T1 showed elongated and, different in size and shape, and ruptured adipocytes with only a few normal adipocytes whereas T2 showed central core of fat with almost intact fat cells Experiment 2 Cell count: P1=1.2/3.2/4.2, P2=1.2/2.4/3.8($\times10^5$ per mL); MTT assay:P1=0.256/0.245/0.258/0.21/0.264, P2=0.12/0.231/0.245/0.313/0.281 in 21 days(absorbance); Histology: P1 showed somewhat evenly distributed normal-looking fat cells and P2 showed relatively irregular shape of fat cells with small blood vessel amongst adiopocytes. Conclusion: Viability was higher in ‘modified tumescent solution’without sodium bicarbonate and triamcinolone and we also found no significantly different viability between using intermittent pressure and using sustained pressure. But in terms of initial viability of fat cell, we can assume that lower intermittent pressure would make better clinical results.

Study(VII) on Development of Charts and Equations Predicting Bearing Capacity for Prebored PHC Piles Socketed into Weathered Rock through Sandy Soil Layers - Allowable Axial Compressive Bearing Capacity Formulae - (사질토를 지나 풍화암에 소켓된 매입 PHC말뚝에서 지반의 허용압축지지력 산정도표 및 산정공식 개발에 관한 연구(VII) - 지반의 허용압축지지력 산정공식 -)

  • Kwon, Oh-Kyun;Nam, Moon S.;Lee, Wonje;Yea, Geu Guwen;Choi, Yongkyu
    • Journal of the Korean Geotechnical Society
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    • v.35 no.12
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    • pp.69-89
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    • 2019
  • Design chart solution and table solution were proposed by Choi et al. (2019a), which conducted a parametric numerical study for the bored PHC piles socketed into weathered rocks through sandy soil layers. Based on the Choi et al. (2019a), the new prediction formulae for mobilized capacity components such as total capacity, total skin friction and skin friction of sand at the settlement of 5% pile diameter were proposed in this study. The proposed prediction formulae (EQ-G1) considers pile diameter, relative embedment length and ${\bar{N}}$ (i.e, corrected N) value and their verification results are as follows. The SRF calculated from the new proposed design method was 71~94%, which are greatly improved compared with results by the existing design method. The design efficiency of bearing capacity was in the range of reasonable design except 4 cases, and the design efficiency of the PHC pile was evaluated as 85%. Therefore, it is possible that allowable compressive load (Pall) of PHC pile can be utilized in the resonable design by means of the new proposed method using EQ-G1 equations. And the other new proposed equations of EQ-G2-3 can be utilized approximately in calculation of axial compressive bearing capacity components for prebored PHC pile.

Patterns of Health-related Quality of Life in Men Who Inject Drugs: A Survey in Southeast Iran

  • Marzieh Nojomi;Maysam Rezapour;Neda Soleimanvandi Azar;Mehdi Darabi;Mehran Asadi-Aliabadi
    • Journal of Preventive Medicine and Public Health
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    • v.57 no.2
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    • pp.148-156
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    • 2024
  • Objectives: Understanding patterns of quality of life in people who inject drugs (PWID) can help healthcare providers plan and manage their health problems in a more focused manner. Therefore, the current study aimed to identify patterns of health-related quality of life in PWID in southeast Iran. Methods: This cross-sectional study was conducted in southeast Iran on men who had injected drugs at least once during the last year. We used convenience sampling in 2 drop-in centers and venue-based sampling at 85 venues. Demographic characteristics, high-risk behaviors, and health-related quality of life were evaluated using the 5-level EQ-5D version (EQ-5D-5L) questionnaire. Latent profile analysis was used to identify patterns of quality of life. Results: This study enrolled 398 PWID, who had a mean age of 34.1±11.4 years. About 47.9% reported a prison history in the last 10 years, 59.2% had injected drugs in the last month, and 31.6% had a history of sharing syringes. About 46.3% reported having 2 or more sexual partners in the last 6 months, and 14.7% had a history of sex with men. Out of the 5 EQ-5D-5L profiles, the fifth profile had the most people (36.6%). Most variations in quality of life were related to pain and discomfort. Conclusions: We showed that the pain and discomfort dimension of EQ-5D-5L had more variation in PWID. This finding will be useful for allocating appropriate interventions and resources to promote health-related quality of life in this population.