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스마트폰을 이용한 뇌졸중 후 상지 편마비 환자의 상지 게임재활훈련 프로그램 개발 및 임상적 유용성 평가에 대한 예비연구 (Development and Clinical Evaluation of the Upper Extremity Rehabilitation Game Program for Patients with Upper Extremity Hemiplegia After Stroke Using Smartphone: Preliminary Study)

  • 임현미;최윤희;백남종;구정훈
    • 대한의용생체공학회:의공학회지
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    • 제36권5호
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    • pp.155-161
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    • 2015
  • In the paper, we developed the mobile based rehabilitation system for patients with upper extremity hemiplegia after stroke and evaluated clinical usefulness and effectiveness of the system. The sensors built in the smartphone were used to track patients' upper limb motion and the movements was transferred to the tablet PC through bluetooth connection so that the game contents could be interact with the movements. The rehabilitation game contents was based on Brunnstrom stage(B-stage), and was designed to lead accurate movement of upper limb. For the clinical evaluation of the effectiveness, 11 patients were recruited and make them perform an exercise of their wrist, shoulder, and forearm using the system for two weeks. The change of upper limb motor function was measured using fugl-meyer assessment(FMA), Brunnstrom stage(B-stage). And the change of quality of life was measured using EuroQoL-5 Dimension(EQ-5D), Beck Depression Inventory(BDI). The results showed significant improvement in upper limb function but not in quality of life. We verified mobile based rehabilitation program could be useful and effective for the clinical use.

여과식 채취방법에 의한 대기오염 총침착물의 특성 -석탄화력발전소 주변지역을 중심으로- (Characteristics of Total Atmospheric Deposition by the Filtration-Sampling Method at Coal-Fired Power Plant Area)

  • 박정호;조인철;최금찬
    • 한국대기환경학회지
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    • 제18권2호
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    • pp.161-170
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    • 2002
  • Total(=wet+dry) atmospheric depositions were collected by filtration-sampling method at 17 sampling sites of the coal-fired power plant area from September 1999 to January 2000. The soluble and insoluble fractions of deposition were also measured to investigate a suitability of simplified collection method for a long-term monitoring of total deposition. In the study, the 50% of sampled soluble fractions showed the electric conductivity (E.C.) of below 50 $\mu$S/cm and the 42% of them showed the lower pH than 5.0. The monthly mean fluxes of water soluble ionic components; S $O_4$$^{2-}$, C $l^{[-10]}$ , N $O_3$$^{[-10]}$ , N $a^{+}$, N $H_4$$^{+}$, $K^{+}$, $Mg^{2+}$, $Ca^{2+}$ were 168.4 kg/k $m^2$.month, 100.5 kg/k $m^2$.month, 88.6kg/k $m^2$.month, 31.3kg/k $m^2$.month, 25.6 kg/k $m^2$.month, 13.3 kg/k $m^2$.month, 8.7 kg/k $m^2$.month, 43.1kg/k $m^2$.month, respectively. The mean ionic concentration of all sample(n=79) was 314 $\mu$eq/ι, with contributions of 24.2% and 23.0% by [nss-C $a^{2+}$] and [nss-S $O_4$$^{2-}$]. The ratio of [N $O_3$$^{[-10]}$ ]/[nss-S $O_4$$^{2-}$] and [N $H_4$-C $a^{2+}$] were found to be 0.52 and 0.68, respectively.espectively.

Relationship between serum sodium level and coronary artery abnormality in Kawasaki disease

  • Park, Sora;Eun, Lucy Youngmin;Kim, Ji Hong
    • Clinical and Experimental Pediatrics
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    • 제60권2호
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    • pp.38-44
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    • 2017
  • Purpose: Kawasaki disease (KD) is an immune-related multisystemic vasculitis that occurs in children, especially ensuing from a coronary artery abnormality. Sodium level is known to be related to vascular injury, which could affect the progress of KD. The purpose of this study was to determine the serum sodium levels that could predict the occurrence of cardiac and coronary artery events in KD. Methods: We conducted a retrospective review of medical records for 104 patients with KD from January 2015 to December 2015. Patients with serum Na levels of <135 mEq/L at the time of initial diagnosis were assigned to the hyponatremia group. Laboratory findings and echocardiographic data were analyzed for various aspects. Results: Among the 104 patients with KD, 91 were included in the study, of whom 48 (52.7%) had hyponatremia. The degree of fever, white blood cell count, percentage of neutrophils, percentage of lymphocytes, total bilirubin level, brain natriuretic peptide level, erythrocyte sedimentation rate, and C-reactive protein level were higher in the patients with hyponatremia. They also demonstrated a trend of larger coronary artery diameters based on Z scores. Conclusion: The severity of vascular inflammation in acute KD with hyponatremia might worsen the prognosis of coronary vasculature. Although no statistically significant correlation was found between the initial serum sodium levels and coronary arteriopathy in the patients with KD in this study, a long-term follow-up study with a larger number of enrolled patients should be designed in the future to elucidate the relationship between serum sodium level and coronary arteriopathy in patients with KD.

외과환자에 발생한 급성신부전의 진단과 치료 (Diagnosis and Management of Acute Renal Failure in Surgical Patient)

  • 권굉보
    • Journal of Yeungnam Medical Science
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    • 제1권1호
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    • pp.13-23
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    • 1984
  • Acute renal failure refers to a rapid reduction in renal function that usually occurs in an individual with no known previous renal disease. Development of a complication of acue renal failure in critically ill surgical patients is not unusual, and it causes high morbidity and mortality. Acute renal failure can be divided as Pre-renal (functional), Renal (organic), and Post-renal (obstructive) azotemia according to their etiologies. Early recognition and proper correction of pre-renal conditions are utter most important to prevent an organic damage of kidney. These measures include correction of dehydration, treatment of sepsis, and institution of shock therapy. Prolonged exposure to ischemia or nephrotoxin may lead a kidney to permanent parenchymal damage. A differential diagnosis between functional and organic acute renal failure may not be simple in many clinical settings. Renal functional parameters, such as $FENa^+$ or renal failure index, are may be of help in these situations for the differential diagnosis. Provocative test utilyzing mannitol, loop diuretics and renovascular dilators after restoration of renal circulation will give further benefits for diagnosis or for prevention of functional failure from leading to organic renal failure. Converting enzyme blocker, dopamine, calcium channel blocker, and propranolol are also reported to have some degree of renal protection from bioenergetic renal insults. Once diagnosis of acute tubular necrosis has been made, all measures should be utilized to maintain the patient until renal tubular regeneration occurs. Careful regulation of fluid, electrolyte, and acid-base balance is primary goal. Hyperkalemia over 6.5 mEq/l is a medical emergency and it should be corrected immediately. Various dosing schedules for medicines excreting through kidney have been suggested but none was proved safe and accurate. Therefore blood level of specific medicines better be checked before each dose, especially digoxin and Aminoglycosides. Indication for application of ultrafiltration hemofilter or dialysis may be made by individual base.

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저칼륨혈증성 횡문근융해증을 동반한 원발알도스테론증 1예 (A Case of Primary Aldosteronism Accompanied by Hypokalemic Rhabdomyolysis)

  • 김홍익;백상아;황현식;이우현;강건우;이인희
    • Journal of Yeungnam Medical Science
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    • 제29권2호
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    • pp.113-117
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    • 2012
  • Primary aldosteronism is characterized by hypertension, hypokalemia, and metabolic alkalosis, associated with excessive aldosterone production and suppressed plasma renin activity. Hypokalemia-induced rhabdomyolysis has been rarely reported in primary aldosteronism patients. This paper reports a case of primary aldosteronism presented with rhabdomyolysis due to severe hypokalemia. A 48-year-old male with a three-year history of hypertension presented himself at the authors' hospital with generalized weakness and myalgia in both legs over a period of several days. His laboratory findings showed hypokalemia (1.8 mEq/L) with elevations of his serum creatine phosphokinase and serum myoglobin. His plasma aldosterone level was also elevated, and his plasma renin activity was reduced. An abdominal computed tomography revealed a 2.0 cm hypodense mass in the left adrenal gland, which suggested adrenal adenoma. The accordingly underwent laparoscopic adrenalectomy. Three months later, his plasma potassium level and blood pressure became normal without the use of medications.

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Stability and antioxidant effect of rapeseed extract in oil-in-water emulsion

  • Zhang, Hua;Shin, Jung-Ah;Hong, Soon Taek;Lee, Ki-Teak
    • 농업과학연구
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    • 제43권2호
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    • pp.249-257
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    • 2016
  • In this study, rapeseed extracts were obtained by supercritical carbon dioxide fluid extraction of defatted rapeseed to evaluate the stability and antioxidant activity of an oil-in-water (O/W) emulsion system. The oil-in-water emulsions were prepared from stripped soybean oil with different concentrations (0.3, 0.4, 0.5, and 0.6%) of rapeseed extract as an emulsifier. Their emulsion stability was compared to that of emulsions prepared with the commercial emulsifier, Tween 20 (Polysorbate 20, 0.2%). After stripping the soybean oil, the total tocopherol content was reduced from 51.4 g/100 g to 1.1 g/100 g. Emulsion stability and oxidative stability of emulsions prepared with Tween 20 and rapeseed extract as emulsifiers were evaluated. For 30 days droplet sizes of emulsions containing rapeseed extract (0.4, 0.5, and 0.6%) were not significantly different (p > 0.05). Similar results were obtained for emulsion stability (ES) and Turbiscan analysis, suggesting that the addition of rapeseed extract increased emulsion stability. The addition of rapeseed extract at more than 0.4% resulted in an emulsion stability comparable to the addition of 0.2% Tween 20. The antioxidative ability of rapeseed extract increased with the amount added in the emulsion. Moreover, the addition of 0.6% rapeseed extract resulted in the lowest emulsion peroxide values (10.3 mEq/L) among all treatments. Therefore, according to the stability of its antioxidative and physical stability properties, rapeseed extract from super critical extraction could be successfully applied to the food and cosmetic industries.

기류의 유입경로가 대관령 지역 안개의 화학조성에 미치는 영향 (Effect of Air-mass Back Trajectory on the Chemical Composition of Cloud/Fog Water at Daegwallyeong)

  • 김만구;이보경;김현진;홍영민
    • 한국대기환경학회지
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    • 제21권3호
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    • pp.343-355
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    • 2005
  • Cloud/fog water was collected at Daegwallyeong, a typical clean environmental area, by using an active fog sampler during the foggy period in 2002, The pH ranged from 3,7 to 6,5 with a mean of 5,0, but the pH calculated from average concentrations of $H^+$ was 4.4. $SO_4^{2-},\;NO_3^-\;and\;NH_4^+$ were predominant ions with average concentrations of 473,3, 463,3 and $576,0\;{\mu}eq/L$, respectively, This showed that cloud/fog water was slightly acidified, but the concentrations of major pollutants were as high as those for polluted area, suggesting effect from long range transported pollutants, Samples were categorized into four groups (E, W, S, N) by applying 48-h back trajectory analysis using the Hybrid Single-Particle Largrangian Integrated Trajectory (HYSPLIT) model. Concentrations of seasalt $(Na^+\;and\;Cl^-)$ were the highest for group E, indicating large input of seasalts by air masses transported from the East Sea. The concentrations of $SO_4^{2-}$ were slightly higher in group W but the difference was not significant. However, the concentrations of $NO_3^-$ were significantly higher in group W than those in other three groups, The median values of cloud/fog water pH for group N and W were below 4,5, which is significantly lower than median values in group E and group S, This suggests that the acidifying pollutants were transported from the Asia continents and Seoul metropolitan area cause acidification of the cloud/fog water in Daegwallyeong.

도로교통소음에 대한 공동주택 내부소음 기준설정에 관한 연구 (A Study on the Indoor Noise Limits of Apartment Houses from the Road Traffic Noise)

  • 이주엽;송민정;장길수;김선우
    • 한국소음진동공학회논문집
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    • 제15권9호
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    • pp.1084-1091
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    • 2005
  • The indoor noise limit for road traffic noises is needed to secure comfortable acoustical quality in apartment houses. To achieve this goal, psycho-acoustic experiments were carried out with road traffic noise sources modulated by the transmission loss characteristics of the external windows. Finally, a correlation analysis between noise rating index and subjective responses, and an analysis of satisfactory percentage of the dose-response curves varied with respondents was conducted. As a result of this study, followings are suggested. (1) On correlation between dose level and psycho-acoustical response, the initial level of negative feeling is located on $40.1\~40.6\;L_{eq}$ dB(A), (2) On the degree of satisfaction to road traffic noise. near $35\;\%$ point being same dissatisfaction degree is to be assumed $40\~41$ dB(A) of indoor noise level presented into three vocabulary. It is suggested to be reasonable level of 40 dB(A) on the indoor noise limits for intruding road traffic noise. and it is appropriate to be the 5 dB level difference between grades. The results of this study may be used to evaluate the acoustic threshold level for road traffic noise or as a basis for specifying the desired acoustic environment of dwellings.

자가 처방 감초 다량 복용 후 발생한 저칼륨성 하지마비 1례 (A Case of Self-prescribed Licorice-induced Hypokalemic Paralysis)

  • 권승원;정환용;윤승규;서유리;박준영;임진욱;정우상;문상관;조기호;김영석
    • 대한한의학회지
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    • 제32권5호
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    • pp.134-138
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    • 2011
  • Glycyrrhetinic acid, which is a component of licorice, can cause hypermineralocorticoidism through the inhibition of $11{\beta}$-hydroxysteroid dehydrogenase. So, a high dose intake of licorice can lead to hypermineralocorticoidism with potassium loss and depression of the renin-angiotensin-aldosterone system. We report a 73-year-old man with muscle weakness of proximal lower limbs with hypokalemia (Serum $K^+$: 1.4 mEq/L) due to taking self-prescribed licorice without OMD's diagnosis. He boiled 60~100g licorice / day in water and drank it intermittently for 1 month due to arthralgia and swelling of both his knees. Patient's serum renin activity and aldosterone level were far beyond the normal range. He also had metabolic alkalosis with pH 7.552. After quitting the licorice, hypokalemia and muscle weakness of proximal lower limbs gradually improved within 1week.

한방차가 시설이용 노인의 뇌기능지수에 미치는 효과 (The Effects of Oriental Herbal Tea on the Brain Function Quotient of Elders at Health Facility)

  • 윤미경;이정은;김수경;이세원;김정화;우귀옥
    • 동서간호학연구지
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    • 제19권2호
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    • pp.128-137
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    • 2013
  • Purpose: This study was performed to identify the effects of oriental herbal tea on the brain function elders at the day care center and the nursing home. Methods: This study used a pre-post quasi-experimental design with a non-equivalent control group. Total 38 of elderly population (20 of experimental group and 18 of control group) was recruited. 100 mL of a type of oriental herbal tea developed for purpose of this study was given to each subject 3 times a day for 30 days (from May to Jun 2013). The brain function quotient was used to measure brain function. The data were analyzed by SPSS/WIN 18.0. Results: After drinking the oriental herbal tea, more significant improvement on attention quotient (AQ), anti-stress quotient (ASQ), emotion quotient (EQ) and brain quotient (BQ) were found in the experimental group than control group. Conclusion: This study shows that oriental herbal tea can be a health promotion option in elders. Therefore the tea can be utilized as an effective intervention for the health of elders in health facilities.