• Proceedings of the KIEE Conference
• /
• 1987.07a
• /
• pp.30-33
• /
• 1987

• Proceedings of the KIEE Conference
• /
• 1987.07a
• /
• pp.38-40
• /
• 1987

• Proceedings of the KIEE Conference
• /
• 1987.07a
• /
• pp.45-46
• /
• 1987

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2531-2535
• /
• 2015

Background: Breast cancer diagnosed in young women may be more aggressive, with higher rates of local and distant recurrence compared to the disease in older women. Epidemiologic evidence suggests that Korean women have a lower incidence of breast cancer than women in the United States, but that they present at a younger age than their American counterparts. We sought to compare risk factors and management of young women with breast cancer in Boston, Massachusetts (US) with those in Seoul, South Korea (KR). Materials and Methods: A retrospective review was performed of consecutive patients less than 35 years old with a diagnosis of breast cancer at academic cancer centers in the US and KR from 2000-2005. Patient data were obtained by chart review. Demographic, tumor and treatment characteristics were compared utilizing Pearson's chisquare or Wilcoxon rank-sum tests where appropriate. All differences were assessed as significant at the 0.05 level. Results: 205 patients from the US and 309 from KR were analyzed. Patients in US were more likely to have hormone receptor positive breast cancer, while patients in KR had a higher rate of triple negative lesions. Patients in US had a higher mean body mass index and more often reported use of birth control pills, while those in the KR were less likely to have a sentinel node procedure performed or to receive post mastectomy radiation. Conclusions: Patients under 35 diagnosed with breast cancer in the US and KR differ with respect to demographics, tumor characteristics and management. Although rates of breast conservation and mastectomy were similar, US patients were more likely to receive post mastectomy radiation. The lower use of sentinel node biopsy is explained by the later adoption of the technique in KR. Further evaluation is necessary to evaluate recurrence rates and survival in the setting of differing disease subtypes in these patients.

• Journal of the Korea Convergence Society
• /
• v.12 no.11
• /
• pp.1-18
• /
• 2021

While content word-based frequency analysis has obvious limitations to intentional deception or irony, KLIWC has evolved into functional word analysis and KrKwic has evolved as a way to visualize co-occurrence frequencies. However, after more than 10 years of development, several issues still need improvement. Therefore, we tried to develop a new psychological language analysis program by analyzing KLIWC and KrKwic. First, the two programs were analyzed. In particular, the morpheme classification of KLIWC and the Korean morpheme analyzer was compared to enhance the functional word analysis function, and the psychological dictionary were analyzed to strengthen the psychological analysis. As a result of the analysis, the Hannanum part-of-speech analyzer was the most subdivided, but KLIWC for personal pronouns and KKMA for endings and endings were more subdivided, suggesting the integrated use of multiple part-of-speech analyzers to strengthen functional word analysis. Second, the research trends of studies that analyzed texts with these programs were analyzed. As a result of the analysis, the two programs were used in various academic fields, including the field of Interdisciplinary Studies. In particular, KrKwic was used a lot for the analysis of papers and reports, and KLIWC was used a lot for the comparative study of the writer's thoughts, emotions, and personality. Based on these results, the necessity and direction of development of a new psychological language analysis program were suggested.

• Journal of Microbiology
• /
• v.45 no.6
• /
• pp.528-533
• /
• 2007

In a previous study we generated an anti-Hepatitis B Virus (HBV) preS1 humanized antibody (HzKR127) that showed in vivo HBV-neutralizing activity in chimpanzees. However, the antigen-binding affinity of the humanized antibody may not be sufficient for clinical use and thus affinity maturation is required for better therapeutic efficacy. In this study, phage display technique was employed to increase the affinity of HzKR127. All six amino acid residues (Glu95-Tyr96-Asp97-Glu98-Ala99-Tyr100) in the heavy (H) chain complementary-determining region 3 (HCDR3) of HzKR127 were randomized and phage-displayed single chain Fv (scFv) library was constructed. After three rounds of panning, 12 different clones exhibiting higher antigen-binding activity than the wild type ScFv were selected and their antigen-binding specificity for the preS1 confirmed. Subsequently, five ScFv clones were converted to whole IgG and subjected to affinity determination. The results showed that two clones (B3 and A19) exhibited an approximately 6 fold higher affinities than that of HzKR127. The affinity-matured humanized antibodies may be useful in anti-HBV immunotherapy.

• Bulletin of the Korean Chemical Society
• /
• v.28 no.10
• /
• pp.1689-1696
• /
• 2007

Equilibrium molecular dynamics (EMD) simulations are used to evaluate the transport coefficients of argonkrypton mixtures at two liquid states (state A: 94.4 K and 1 atm; state B: 135 K and 39.5 atm) via modified Green-Kubo formulas. The composition dependency of the volume at state A obeys close to the linear model for ideal liquid mixture, while that at state B differs from the linear model probably due to the high pressure. The radial distribution functions for the Ar-Kr mixture (x = 2/3) show a mixing effect: the first peak of g11 is higher than that of g(r) for pure Ar and the first peak of g22 is lower than that of g(r) for pure Kr. An exponential model of engineering correlation for diffusion coefficient (D) and shear viscosity (η) is superior to the simple linear model for ideal liquid mixtures. All three components of thermal conductivity (λpm, λtm, and λti) at state A and hence the total thermal conductivity decrease with the increase of x. At state B, the change in λtm is dominant over those in λpm and λti, and hence the total thermal conductivity decrease with the increase of x.

• Analytical Science and Technology
• /
• v.12 no.2
• /
• pp.94-98
• /
• 1999

An analysis method of components and isotopic compositions of low pressure gases from nuclear fuel rod using quadrupole mass spectrometer was studied. The calibration curves of each gas in pure and mixtures of He, $N_2$, $O_2$, Ar, Kr and Xe were obtained as a function of pressure and concentration, respectively. Effect of molecular leak, located between sample chamber and analyser chamber, on the sensitivites was also studied. The results suggested that samples could be analysed accurately at the same analytical condition as that of synthetic gas mixture. The difference of sensitivities among isotopes of Kr and Xe was not observed in the range of measured pressure.

• The Bulletin of The Korean Astronomical Society
• /
• v.41 no.2
• /
• pp.39.2-40
• /
• 2016

The molecular gas surrounding an H II region is thought to be a place where star formation can be induced. Such triggered star formation can arise form the overpressurization of existing density enhancements or thought the collapse of a swept up layers of material. In this talk, We will discuss the results of a study of star-formation activity associated with the outer Galaxy ring-shaped H II regions KR 7, KR 81, KR 120 and KR 140 using archival Spitzer and WISE data along with the JHK observations. We used CO data cubes from the FCRAO and TRAO in order to define extent of the molecular cloud associated each HII region. Using the infrared data sets, We identified and classified YSO populations within each molecular cloud using measures such as the class I/II ratio and YSO spatial density. Along with this, one of the main question in the study of star formation is how protostar accrete material from their parent molecular clouds and observations of infall motions are needed to provide direct evidence for accretion. Combining our observation of the YSO population distribution with time scales associated with YSO evolution and HII expansion, we investigated the possible significance of triggered star formation in the molecular cloud surrounding each region.

• Proceedings of the KIEE Conference
• /
• 2001.07c
• /
• pp.1744-1746
• /
• 2001

In this paper, we investigated the breakdown characteristics of Ar, Kr and $N_2$ gas in pure states with pressure range of 58.8-137.3[kPa] under uniform and non-uniform fields, and the measured values are compared with those in Ar/$N_2$ gas mixtures. From these results, the breakdown voltages of $N_2$ gas in uniform field were increased about 4.8 and 4.4 times than those of Ar and Kr gas, respectively. Breakdown voltages of Ar/$N_2$ gas mixtures were decreased with decreasing the mixture ratio of $N_2$ gas. Breakdown voltages of Ar(70%)/$N_2$(30%) gas mixtures in the pressure of 101.3[kPa] (gap length : 3[mm]) were increased 1.9 times than those of pure Ar gas.