• Journal of Life Science
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• v.31 no.2
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• pp.144-148
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• 2021

This study aimed to analyze the content and composition of a biological amine, cadaverine, isolated from the venom of worker honeybees (Apis mellifera L.). This biological amine―which has diverse functionality, such as anti-inflammatory and antibacterial effects―has not been previously reported in bee venom. An assay completed in 13 minutes was developed for the cadaverine present in the bee venom using an ultra-performance liquid chromatograph and a Halo C18 column with acetonitrile and water as the mobile phase. The specificity, accuracy, and precision of the assay were verified, and the assay was validated. The linearity for cadaverine in the bee venom was R2=0.99 or above, indicating a moderate level. The limit of detection and limit of quantification were both 0.3 ㎍/ml, and the rate of recovery was 97.6%-99.1%. The relative standard deviation (RSD) of the intra-day precision and inter-day precision for cadaverine was 0.25%-0.44% and 0.25%-1.25%, respectively, with an RSD that fell within 5% indicating excellent precision. Through this novel assay, it was found that the mean content of cadaverine was 1.10±0.05 mg/g. Our results indicated that the linearity, limit of detection, limit of quantification, and rate of recovery of the cadaverine assay were of a satisfactory level, and the cadaverine content of the bee venom was ably determined. This study provides basic data on cadaverine in bee venom, which will prove useful in further studies on the bioactivity of this component.

• Tuberculosis and Respiratory Diseases
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• v.43 no.2
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• pp.274-279
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• 1996

Pulmonary veno-occlusive disease is a rare cause of pulmonary hypertension in which the primary abnormality is obliterative obstruction of pulmonary veins, especially venules. Clinicaly, we should suspect this disease in the case of congestive cardiac failure with pulmonary hypertension, chronic interstitial pulmonary edema, and normal or elevated wedge pressure on cardiac catheterization. We experience a case of pulmonary hypertension due to pulmonary veno-occlusive disease. A 55-years -old woman developed progressive dry cough and dyspnea for 3 months. Physical examination showed normal heart sounds, diffuse crackles in the whole lung fields. The liver was not palpable and pitting edema was absent. The diagnosis was made by chest HRCT, 2-D echocardiography, normal pulmonary capillary wedge pressure on cardiac catheterization, and confirmed by thoracoscopic lung biopsy. This patient was treated with vasodilator(calcium antagonist) and with mild symptomatic improvement. We reported a case of pulmonary veno-occlusive disease with review of literatures.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.439-439
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• 2011

최근 이상기후로 인해 세계의 기후, 날씨가 변화하는 추세이다. 이에 따라 한국, 프랑스, 미국 등 세계 각지에서 이상홍수 및 이상가뭄이 발생하고 이로 인한 재산 및 인명피해가 빈번한 현황이다. 따라서 전 세계적으로 기후변화를 고려하여 홍수피해를 저감하고자 많은 노력을 기울이고 있으며, 그러한 방법 중에서도 특히 설계 또는 계획수립 시에 많이 사용되는 방식으로 수치해석 및 수리실험 방법을 들 수 있다. 특히, 수치해석은 수리실험에 비해 비교적 짧은 시간과 경제적인 장점이 있으므로 많이 이용되는 방법 중의 하나이다. 따라서 본 연구에서는 수치해석을 통해 프랑스 남부에 위치한 니스 지역 Var강의 역사상 가장 큰 실강우에 대하여 다양한 방식의 수치해석을 수행하고 수위 관측지점의 수위자료와 비교분석하고자 한다. 본 연구에서는 대상지역을 프랑스 남부에 위치한 니스지역의 Var강으로 선정하였다. 이 지역은 지중해성 기후에 속해 건조하고 따뜻한 날씨였지만 최근 이상기후로 인해 잦은 강우와 홍수 등이 발생하고 있다. 가장 심한 피해가 발생했던 1994년 11월에 발생한 폭우로 인하여 최대 유량이 $3,500m^3/s$까지 관측 되었으며 이는 평균 유량인 $50~100m^3/s$의 35~70배에 달하는 유량이다. 이 홍수로 인해 Var강 유역의 많은 지역이 물에 잠기고 2개의 수중구조물이 파괴되는 등 많은 피해가 발생하였다. 본 연구에서 사용된 수치모형은 미 공병단의 HEC-HMS와 상용 프로그램인 MIKE11과 ISIS이다. MIKE11과 ISIS는 1차원 수리분석모형 프로그램으로써 흐름, 속도, 유량, 수질, 유사이동 등 개수로에서 여러 수리학적 현상을 분석할 수 있는 프로그램이다. 실제 수위자료와 수치모의를 통한 결과값의 비교를 위해 GIS를 통해 얻은 유출계수, 유로경사, 소유역 분할 등을 이용하고 역사상 가장 크게 발생한 1994년의 실강우 이용하여 HEC-HMS을 통해 수문곡선을 작성한 후 동일한 매개변수를 이용하고 검 보정을 통해 MIKE11과 ISIS를 이용하여 수치모의를 실시하였고 실제 수위자료와 프로그램 MIKE11와 ISIS의 결과값을 분석 및 비교하였다. Var강 유역에서 수치모의를 한 결과, 각 프로그램을 사용한 결과값은 실제 수위자료와 비슷한 경향을 보였으며 또한 동일한 매개변수를 이용하였을 때 각 프로그램을 사용한 결과값도 유사한 경향을 보였다. 검 보정을 실시 한 후 ISIS의 결과값이 실제 수위자료와 더 흡사한 것으로 나타났다.

• Economic and Environmental Geology
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• v.47 no.2
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• pp.169-180
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• 2014

Surface geological and trench surveys and drilling exploration (total length, 1,100 m; 9 drill holes) were carried out to secure new Au ore bodies in the area($0.96km^2$) of Actosity gold field, where is located at the western Kuldjuktau mineralized district in the middle territory of Uzbekistan. Several Au ore bodies occurring as tabular or lens shapes with thickness of 0.5~35 m were newly discovered on the outcrops and extended to $N40{\sim}70^{\circ}\;W$ direction with dipping of $70{\sim}90^{\circ}$ SW or NE. Indicated ore resource of gold with Au grade of 0.25~3.52 mg/kg was newly estimated by 2,382 t(gold resource of 2.5 t) as a result of 9 drilling exploration in 2010~2012 from the Actosity gold field. Judging from the ore resources and Au grade of the Actosity gold field, economic potentiality of mining development seems to be low. Because of high possibility to secure new ore resources through more detailed exploration works from the Actosity area, the growth of econonic value will be expected by a mine of middle scale.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.12
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• pp.1842-1846
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• 2012

The effects of hurdle techniques on the reduction of Bacillus cereus spores in Doenjang and Gochujang were investigated. In our system, Bacillus cereus spores were artificially inoculated into Doenjang and Gochujang. Hurdle techniques used in this study were additives (3% ethyl alcohol-0.03% oregano extract), Joule heating ($95^{\circ}C$ for 5 min), and hydrostatic pressure (500 MPa for 5 min at $45^{\circ}C$). Additive-Joule (AJ) and additive-Joule-pressure (AJP) treatments for Doenjang resulted in a 2.80 log and 3.74 log reduction, respectively, while treatments for Gochujang resulted in a 4.71 log and 5.60 log reduction, respectively. This suggests a high synergistic effect of Joule heating with additive treatment in Doenjang and Gochujang. A combination ofg hurdles such as additives, Joule heating, and hydrostatic pressure also kept Bacillus cereus spore counts low during storage at $30^{\circ}C$. Therefore, Bacillus cereus spores inoculated into Doenjang and Gochujang can be effectively reduced through combined treatments, including AJ or AJP.

• Korean Journal of Plant Taxonomy
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• v.50 no.3
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• pp.279-317
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• 2020

This study presents the flora of nonvascular plants (bryophytes) and vascular plants within the Wangpicheon Ecosystem and Landscape Conservation Area in Korea. The time of the survey was divided into four seasons. The fieldwork was conducted for a total of 18 days from November of 2016 to October of 2017. The land plants in the Wangpicheon conservation area were identified as 758 taxa with 164 families, 455 genera, 698 species, 10 subspecies, 47 varieties and 3 forms. Among them, bryophytes amounted to 122 taxa and vascular plants numbered 636 taxa. Native plant amounted to 693 taxa. In total, there are 113 floristic target species in Korea, including one level V taxon, in this case Swertia wilfordii; six level IV taxa; 31 level III taxa; 38 level II taxa; and 37 level I taxa. There are nine endemic plants, including Sillaphyton (=Peucedanum) podagraria, which is the endemic genus; two rare plants; fifteen northern plants; and one southern plant as target plants adaptable to climate change. Also, there are forty-six naturalized plants and five ecosystem-disturbance organisms. The results of this study suggest several species that should be preserved and can serve as basic information with which to establish conservation and management plans for the Wangpicheon conservation area.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.259-266
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• 2005

Tension headache is one of the most common form of headache. It may occur at any age, but is most common in adults and adolescents. One cause of this muscle contraction is a response to stress that induces changes and imbalance on autonomic nerve system. And it is not easy to classify the type of tension headache simply in oriental medicine. In this case, we described a 25-year old woman who diagnosed as tension headache. She complained headache with nausea and vomiting, and her condition was improved through oriental medical treatment.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2020.08a
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• pp.70-70
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• 2020

참취(Aster scaber)는 국화과에 속하는 여러해살이식물로 취나물로 분류되어 전국에서 재배되고 있으며 주로 시설재배지 조기재배 작형으로 많이 재배하고 있다. 참취의 잎과 줄기는 맛과 향기가 독특하여 예로부터 생채, 묵나물 등으로 이용되어 왔으며 칼슘, 철분, 비타민 A 등이 풍부하여 건강식품으로서도 가치가 높고 한약재로도 사용되기도 한다. 최근에는 항암효과와 더불어 콜레스트롤을 저하시키는 약리적 효능이 있는 것으로 밝혀져 기능성 식품으로도 각광 받고 있다. 참취 시설재배 시 통상 3년 마다 갱신이 이루어지고 있는데 그 이유로는 시설재배지 특성상 양분의 과다투입에 의한 염류집적과 잦은 관수로 물리성이 악화되어 참취의 생육이 저하되어 수량이 감소하는 결과를 초래한다. 본 연구는 토양개량제 처리에 따른 토양 물리화학성과 참취의 생육에 미치는 영향을 검토하여 참취 시설재배 농가에 활용할 수 있는 방안을 개발하고자 시험을 수행하였다. 2018년 4월부터 2020년 7월까지 전라북도 농업기술원 허브산채시험장에서 참취 시설재배를 대상으로 무처리, 볏짚 1,000kg/10a, 왕겨숯 1,000kg/10a, 야자섬유 1,000kg/10a, 4처리구로 하여 시기별 토양특성 변화 및 생육 상황을 조사하였다. 자재 처리 후 3년차 토양 물리성의 변화는 볏짚 시용에서 가장 낮은 용적밀도 1.23g/cm³와 가장 높은 공극률 53.50%을 보였다. 토양 삼상은 고상은 왕겨숯에서 49.41%로, 액상은 왕겨숯에서 24.92%로, 기상은 볏짚에서 32.09%로 가장 높았다. 토양화학적 특성을 조사한 결과 토양 pH는 7.2~7.3, 토양유기물 함량은 32~39g/kg, 유효인산 함량은 440~487mg/kg 이었으며 처리 전 토양에 비하여 유기물 함량은 증가하고 유효인산은 낮아지는 경향을 보였다. 치환성 양이온 K, Ca, Mg는 K는 0.77~0.88cmolc/kg로 낮아졌고, Ca와 11.56~14.09cmolc/kg, Mg는 2.93~3.22cmolc/kg로 증가하였다. 참취 생육특성은 초장은 24.8~26.4cm, 엽장은 8.3~8.7cm, 엽폭은 6.3~6.7cm, 줄기수는 6.9~7.2주로 대조구에 비해 좋은 생육 상황 상황을 보였으며, 수량은 919~1,161kg/10a 으로 자채 처리구에서 대조구에 비해 수량성 또한 높았다 참취 다년재배지 토양개량제 시용함으로써 토양의 유기물함량 증가와 토양의 용적밀도 감소와 토양 공극율 증가 등 토양의 물리화학성을 개선할 수 있을 것으로 기대된다.

• Journal of Gastric Cancer
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• v.6 no.4
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• pp.207-213
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• 2006

Purpose: This study was performed to evaluate the usefulness of computed tomography (CT) gastrography in the surgical management of a gastric gastrointestinal stromal tumor (GIST). Materials and Methods: We retrospectively analyzed the clinicopathologic data of 38 patients who had undergone CT gastrography from among patients who had gastric GISTS surgically resected at the Department of Surgery, Seoul National University Hospital, between January 2001 and February 2006. We compared CT gastrography data, including tumor size and location and distance from the gastroesophageal junction or pylorus with endoscopic, surgical and pathologic findings. Results: The longitudinal tumor locations on CT gastrography and endoscopy were identical to the surgical findings. For tumor sizes on CT gastrography of less than 5 cm, we performed 11 (42.3%) laparoscopic wedge resections from among 26 cases. In the 12 cases with tumor sizes of 5 cm or over, only 1 (8.3%) laparoscopic wedge resection was performed. When the tumor was located in the middle third of the stomach, a laparoscopic wedge resection was performed in 88.9% (8/9) of the cases, but when it was located in the upper or lower third, a laparoscopic wedge resection was performed in only 13.8% (4/29) of the cases. Conclusion: Three-dimensional information from CT gastrography allows the surgeon to perform preoperative planning, including accurate localization.

• Journal of Veterinary Clinics
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• v.27 no.6
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• pp.679-685
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• 2010

Many animal models of osteoarthritis (OA) have been developed, aimed at understanding the long-term progression of OA and difficulty of identifying patients in the initial stage of the disease. In canines, coxofemoral luxation and hip dysplasia are common orthopedic ailments related to OA in the hip joint. Transecting the ligament of the head of the femur (LHF) aids in diagnosis of coxofemoral joint OA. Presently, mobility of this joint was increased by transected LHF in 10 mature, 2-3-year-old (average $2.57{\pm}0.20$ years), healthy male beagles. The animals were normally gaited 1-week post-operatively. During the experimental period, examinations including X-ray, complete blood count and serum chemistry were unremarkable. Proteomic examination revealed protein alterations in synovial fluid, with significant increases in Vitamin D-binding protein precursor (ANOVA, p < 0.004) and Kinogen-1 (ANOVA, p < 0.039). Both proteins correlated with arthritis.