• 약학회지
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• 제14권1_2호
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• pp.1-14
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• 1970

Seventeen N,N/sup I/-disubstituted thiourea derivatives were synthesized by the Hugershof reaction and reported. Antitumor activities of the synthesized compounds against ascitic Ehrlich Carcinoma and ascitic sarcoma 180 were reported. It was found that 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis (2-carboxyphenyl)-2,2/sup I/-dithiourea was considerably active against ascitic Ehrlich Carcinoma and Sarcoma 180 respectively. 1-(2-Carboxyphenyl)-3-(p-ethoxyphenyl)-2 thiourea was active against ascitic Sarcoma 180. 1-Salicyloyl-3-(p-ethoxyphenyl)-2-thiourea and 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis(2-hydroxyethyl)-2,2/sup I/-dithiourea were active against ascitic Ehrlich Carcinoma. Antitubercular activities of the synthesized compounds against Mycobacterium tuberculosis H/sub 37/ R/sub v/ were also reported. It was found that 1-Isonicotinyl-4-cyclohexyl-3-thiosemicarbazide was considerably active at 100 .mu.g/ml. 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis(2-hydroxyethyl)-2,2/sup I/-dithiourea and 1-Salicyloyl-3-(p-ethoxyphenyl)-2-thiourea were active at 1000 .mu.g/ml respectively. Antibacterial activities of nine compounds of the synthesized compounds against S. aureus and E. Coli were reported. It was found that 1,1-(p-Phenylene)-4,4/sup I/-bis(isonicotinyl)-2,2/sup I/-dithiosemicarbazide and 1-Isonicotinyl-4-cyclohexyl-3-thiosemicarbazide were considerably active against S. aureus and E. Coli respectively. 1-(6-Methyl-2-benzothiazolyl)-3-(1-naphthyl)-2-thiourea was active against S. aureus. 1,1/sup I/-(p-Phenylene)-3,3/sup I/-bis (2-hydroxyethyl)-2,2/sup I/-dithiourea was active against E. Coli.

• 호남수학학술지
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• 제27권2호
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• pp.243-250
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• 2005

Given operators X and Y acting on a separable Hilbert space ${\mathcal{H}}$, an interpolating operator is a bounded operator A such that AX = Y. We show the following: Let ${\mathcal{L}}$ be a subspace lattice acting on a separable complex Hilbert space ${\mathcal{H}}$. and let $X=(x_{ij})$ and $Y=(y_{ij})$ be operators acting on ${\mathcal{H}}$. Then the following are equivalent: (1) There exists an invertible operator $A=(a_{ij})$ in $Alg{\mathcal{L}}$ such that AX = Y. (2) There exist bounded sequences {${\alpha}_n$} and {${\beta}_n$} in ${\mathbb{C}}$ such that $${\alpha}_{2k-1}{\neq}0,\;{\beta}_{2k-1}=\frac{1}{{\alpha}_{2k-1}},\;{\beta}_{2k}=-\frac{{\alpha}_{2k}}{{\alpha}_{2k-1}{\alpha}_{2k+1}}$$ and $$y_{i1}={\alpha}_1x_{i1}+{\alpha}_2x_{i2}$$ $$y_{i\;2k}={\alpha}_{4k-1}x_{i\;2k}$$ $$y_{i\;2k+1}={\alpha}_{4k}x_{i\;2k}+{\alpha}_{4k+1}x_{i\;2k+1}+{\alpha}_{4k+2}x_{i\;2k+2}$$ for $$k{\in}N$$.

• 대한예방한의학회지
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• 제21권1호
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• pp.95-106
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• 2017

Objectives : Although interest in preventive medicine has increased recently, "Mibyeong", the preventive concept of Korean medicine, is still unfamiliar to the general public. Therefore, this study aims to investigate the concept of Mibyeong and users used on the Internet. Methods : Naver (www.naver.com), which has the highest ranking in terms of market share, number of visitors, search time share, and community category share, has been selected as a search target and jisik-iN Q&A and posts of cafe about Mibyeong were searched for recently approximately 6 years. Results : 105 cases of Jisik-iN Q&A and 283 cases of cafe posts were searched. Overall, the number of Jisik-iN Q&A and cafe posts's Mibyeong term usage was the highest in 2013. In the Internet user category, Mibyeong Term was used most commonly in the Jisik-iN Q&A by Korean medicine related medical personnel (29 cases, 28%) and in the cafe other health-related workers (87cases, 31%). In Mibyeong related cafe classification, Information Exchange (220 cases, 77%) was the most frequent and besides 39 cases (14%) used in Operation of Medical Institutions. And the concept of Mibyeong was often used as symptom-based rather than diagnostic test or disease (Cafe posts 52%, Jisik-iN Q&A 70%), in particular, topic of Mibyeong related Jisik-iN Q&A was used in the order of pain (31 cases, 16%), cancer (17 cases, 9%), fatigue (11 cases, 6%). Conclusions : This study has significance as basic research data of general Internet user group and can be used as fundamental data for awareness promotion, publicity and necessity of Mibyeong.

• 대한수의학회지
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• 제41권3호
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• pp.343-350
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• 2001

The neutralization epitopes of the outer capsid protein VP4 of a porcine rotavirus, Gottfried strain, were studied using neutralizing monocolonal antibodies(N-MAbs). Eight N-MAbs which are specific for the VP4 of Gottfried strain were used for analyzing the antigenic sites of VP4. Three different approaches were used for this analysis; i)testing the serological reactivity of each N-MAb against different G and P types of human and animal rotavirusese ii) analyzing N-MAb-resistant viral escape mutants and iii) performing nucleotide sequence analysis of the VP4 gene of each N-MAb-resistant viral escape mutant. From experimental results, at least four antigenic sites(I, II, III, and IV) were identified. Antigenic site I recognized by N-MAbs 24B9, 23G10, and 26A2 was separated from antigenic site II recognized by N-MAbs 30H5, 32B3, and 29B3. However, these antigenic sites were overlapped with antigenic site III recognized by N-MAb 21A1. The other antigenic site IV recognized by N-MAb 16D2 was separated from antigenic sites I, II, and III.

• 한국언어정보학회지:언어와정보
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• 제19권2호
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• pp.19-36
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• 2015

The aim of this paper is to investigate the usage of Korean markers -(n)un and -i/ka in editorial texts focusing on information structure. Noun phrases ending with the markers -(n)un and -i/ka were annotated semi-automatically using a corpus obtained from an online newspaper. Two important factors to determine the choice of markers were examined with the annotated data: referential givenness/newness and position in a sentence. Referential givenness and newness were adopted as indicators of information structure, topic and focus respectively. In addition to quantitative analysis, qualitative analysis was conducted on the selected data. The results suggest that both the marker -(n)un and -i/ka could carry a topic and a focus reading. Sentence position also played a crucial role in determining the marker, and the marker -i/ka was used more frequently in a later position of a sentence than the marker -(n)un.

• Korean Journal of Mathematics
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• 제28권3호
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• pp.613-621
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• 2020

In this paper, we investigate the general solution and the Hyers-Ulam stability of n-variable additive functional equation of the form $${\Im}\(\sum\limits_{i=1}^{n}(-1)^{i+1}x_i\)=\sum\limits_{i=1}^{n}(-1)^{i+1}{\Im}(x_i)$$, where n is a positive integer with n ≥ 2, in Banach spaces by using the direct method.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제11권4호
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• pp.287-292
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• 2004

The operator $A \; {\in} \; L(H_{i})$, the Banach algebra of bounded linear operators on the complex infinite dimensional Hilbert space $\cal H_{i}$, is said to be p-hyponormal if $(A^\ast A)^P \geq (AA^\ast)^p$ for $p\; \in \; (0,1]$. Let (equation omitted) denote the completion of (equation omitted) with respect to some crossnorm. Let $I_{i}$ be the identity operator on $H_{i}$. Letting (equation omitted), where each $A_{i}$ is p-hyponormal, it is proved that the commuting n-tuple T = ($T_1$,..., $T_{n}$) satisfies Bishop's condition ($\beta$) and that if T is Weyl then there exists a non-singular commuting n-tuple S such that T = S + F for some n-tuple F of compact operators.

• 충청수학회지
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• 제14권1호
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• pp.1-6
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• 2001

We investigate the relationships between the Gottlieb groups and the generalized Gottlieb groups, and study some properties of the generalized Gottlieb groups. Lee and Woo [5] proved that $G_n(X,i_1,X{\times}Y){\simeq_-}G_n(X){\oplus}{\pi}_n(Y)$. We can easily re-prove the above main theorem of [5] using some properties of the generalized Gottlieb groups, and obtain a more powerful result as follows; if $F{\rightarrow}^iE{\rightarrow}^pB$ is a homotopically trivial fibration, then $G_n(F,i,E){\simeq_-}{\pi}_n(B){\oplus}G_n(F)$.

• 대한수학회지
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• 제49권2호
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• pp.251-263
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• 2012

A CW complex B is said to be I-trivial if there does not exist a $\mathbb{Z}_2$-map from $S^{i-1}$ to S(${\alpha}$) for any vector bundle ${\alpha}$ over B a any integer i with i > dim ${\alpha}$. In this paper, we consider the question of determining whether $\Sigma^k\mathbb{R}P^n$ is I-trivial or not, and to this question we give complete answers when k $\neq$ 1, 3, 8 and partial answers when k = 1, 3, 8. A CW complex B is I-trivial if it is "W-trivial", that is, if for every vector bundle over B, all the Stiefel-Whitney classes vanish. We find, as a result, that $\Sigma^k\mathbb{R}P^n$ is a counterexample to the converse of th statement when k = 2, 4 or 8 and n $\geq$ 2k.

• 대한수학회보
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• 제46권4호
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• pp.617-626
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• 2009

Let {$Y_i$,-$\infty$ < i < $\infty$} be a doubly infinite sequence of i.i.d. random variables with E|$Y_1$| < $\infty$, {$a_{ni}$,-$\infty$ < i < $\infty$ n $\geq$ 1} an array of real numbers. Under some conditions on {$a_{ni}$}, we obtain necessary and sufficient conditions for $\sum\;_{n=1}^{\infty}\frac{1}{n}P(|\sum\;_{i=-\infty}^{\infty}a_{ni}(Y_i-EY_i)|$>$n{\epsilon})$<{\infty}$. We examine whether the result of Spitzer [11] holds for the moving average process, and give a partial solution.