• Biomedical Engineering Letters
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• 제8권4호
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• pp.399-404
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• 2018

The purpose of this study was to evaluate the accuracy of a mobile wireless digital automatic blood pressure monitor for clinical use and mobile health (mHealth). In this study, a manual sphygmomanometer and a digital blood pressure monitor were tested in 100 participants in a repetitive and sequential manner to measure blood pressure. The guidelines for measurement used the Korea Food & Drug Administration protocol, which reflects international standards, such as the American National Standard Institution/Association for the Advancement of Medical Instrumentation SP 10: 1992 and the British Hypertension Society protocol. Measurements were generally consistent across observers according to the measured mean ${\pm}SD$, which ranged in $0.1{\pm}2.6mmHg$ for systolic blood pressure (SBP) and $0.5{\pm}2.2mmHg$ for diastolic blood pressure (DBP). For the device and the observer, the difference in average blood pressure (mean${\pm}$SD) was $2.3{\pm}4.7mmHg$ for SBP and $2.0{\pm}4.2mmHg$ for DBP. The SBP and DBP measured in this study showed accurate measurements that satisfied all criteria, including an average difference that did not exceed 5 mmHg and a standard deviation that did not exceed 8 mmHg. The mobile wireless digital blood pressure monitor has the potential for clinical use and managing one's own health.

• Journal of Preventive Medicine and Public Health
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• 제13권1호
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• pp.27-34
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• 1980

Purpose of this study is to find out proper means of estimating the urinary mercury excretion in the normal individuals. Whole void volume was collected every 2 hours beginning from 6 o'clock in the morning until 6 o'clock next morning. Mercury excretion in each urine specimen was measured by NIOSH recommended dithizone colorimetric method (Method No.: P & CAM 145). Urinary concentration of mercury was adjusted by two means: specific gravity of 1.024 and a gram of creatinine excretion per liter of urine comparing the data with the unadjusted ones. Mercury excretion in 24-hour urine specimen was calculated by adding the amounts measured with the hourly collected specimens of each individual. Statistical analysis of the urinary mercury excretion revealed the following results: 1. Frequency distribution curve of mercury excreted in urine of hourly specimens was best fitted to power function expressed in the form of $y=ax^b$. Adjustment of the urinary mercury concentration by creatinine excretion was shown to be superior($y=1674x^{-1.52},\;r^2=0.95$) over nonadjustment($y=2702x^{-1.57},\;r^2=0.92$) and adjustment by specific gravity of 1.024($y=4535x^{-1.66},\;r^2=0.93$). 2. Both log-transformed mercury excretion in hourly voided specimens and mercury excretion itself in 24 hour specimens showed the normal distributions. 3. The frequency distribution of mercury adjusting the urinary concentration of mercury by creatinine excretion was best fitted to a theoretical normal distribution with the sample means and standard deviation than those unadjusted or adjusted with specific gravity of 1.024. 4. Average urinary mercury excretions in 24-hour urine specimen in an individual were as follows: a) Unadjusted mercury excretion mean and standard deviation : $$18.6{\pm}13.68{\mu}gHg/l$$. median : $$16.0\;{\mu}gHg/l$$. range : $$0.0-55.10\;{\mu}gHg/l$$. b) Adjusted with specific gravity mean : $$20.7{\pm}11.76\;{\mu}gHg/l{\times}\frac{0.024}{S.G-1.000}$$ median : $$20.7\;{\mu}gHg/l{\times}\frac{0.024}{S.G-1.000}$$ range : $$0.0-52.9\;{\mu}gHg/l{\times}\frac{0.024}{S.G-1.000}$$ c) Adjusted with creatinine excretion mean and standard deviation : $$10.5{\pm}6.98\;{\mu}gHg/g$$ creatinine/l median : $$9.4\;{\mu}gHg/g$$ creatinine/l range : $$0.0-26.7\;{\mu}gHg/g$$ creatinine/l 5. No statistically significant differences were found between means calculated from 24-hour urine specimens and those from hourly specimens transformed into logarithmic values. (P<0.05).

• 환경생물
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• 제24권1호
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• pp.46-52
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• 2006

세포에 미치는 염화수은(II)과 이온화 방사선의 영향과 수은 처리 전 후 방사선 조사 시 그 상호 작용에 관해 알아보고자 본 연구를 수행하였다. 염화수은(II)의 독성정도를 알아보기 위하여 사람의 자궁암 세포에 농도별로 염화수은(II)을 처리하였다. 세포의 생존율은 3가지 농도(1,0. 1,0. $0.01\;{\mu}M$)모두에서 유의하게 감소하였으며 이미 $0.1\;{\mu}M$에서 약 73%의 생존율이 감소하는 것으로 나타났다. 염화수은(II)과 방사선의 단독처리 시 DNA의 손상 정도에 비해 복합처리 시의 DNA손상 정도가 $2\sim4$배 정도 확연히 높아짐을 볼 수 있었다. 특히 방사선 후 수은 처리군은 DNA손상의 정도가 다른 처리군에 비하여 높게 나타났는데 이는 이미 기존의 보문에서 밝혀진 바와 같이 수은의 DNA수복에 관련되어 있는 Fpg protein에 미치는 영향 때문으로 사료된다. 이미 방사선에 의해 산화적 손상을 입은 DNA의 수복 기작을 수은이 방해하여 좀 더 높은 손상을 가져오는 것을 확인할 수 있었다.

• 한국식품영양과학회지
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• 제15권2호
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• pp.144-147
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• 1986

무기-Hg을 용해시킨 용액에 생선을 침지(浸漬), 인공적으로 오염(汚染)시켜 흐르는 수도물에 시간별로 수세하고 또 농도별의 초산용액에 침지(浸漬)한 후의 Hg 함량(含量) 변화를 살펴본 결과는 아래와 같다. 1. Hg처리를 하지 않은 시판 도루묵의 Hg함량(含量)은 건물중(乾物重)으로 0.027ppm, 정어리는 0.020ppm이었다. 2. 1ppm $HgCl_2$ 용액에 24시간 침지(浸漬)한 후 유수(流水)에서의 수세 시간별 Hg함량(含量) 변화를 보면 도루묵은 9분동안 씻은 것이 Hg함량(含量)이 가장 낮았으며 수세하지 않은 침지구(浸漬區)에 비해 약 25% 잔존하였다. 정어리는 3분동안 수세한 것이 가장 함량이 낮았으며 침지구(浸漬區)에 비해 약 77% 잔존하였다. 3. 농도별 초산용액에 처리한 시료의 Hg함량(含量)변화는 도루묵의 경우 3% 초산용액에 처리한 것이 가장 잔존량이 적었으며 1분간 수세한 구(區)에 비해 약 64% 감소하였다. 정어리는 1% 초산용액에 처리한 것이 가장 잔존량이 적었으며 1분 수세한 구(區)에 비해 약 16% 감소하였다.

• Bulletin of the Korean Chemical Society
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• 제32권11호
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• pp.3959-3962
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• 2011

A simple propargylamide-fuctionalized chemodosimeter was prepared for the ratiometric fluorescence detection of mercuric ions in HEPES buffer. The chemodosimeter exhibited $Hg^{2+}$-induced propargyl amide-tooxazole transformation, with a significant accompanying ratiometric change in fluorescence. It afforded high selectivity for mercuric ion detection without any competitive inhibition by common alkali, alkaline earth, or other transition metal ions. The probe showed a $17{\times}10^{-6}M$ detection limit for $Hg^{2+}$ ions and potential applicability for detecting aqueous $Hg^{2+}$ ions.

• Journal of Preventive Medicine and Public Health
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• 제17권1호
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• pp.245-250
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• 1984

Reciprocal exchanges of DNA in sister chromatids (SCEs) are induced by various carcinogens and mutagens, although the quantitative relationship between the number of mutations and SCEs induced varies among chemicals. Nevertheless, the analysis of SCEs production by various agents often proposed as a sensitive and quantitative assay for mutagenicity and cytotoxicity. Mercury, even if which has no evidences for mutagenicity and carcinogenicity, is reported to exert some cytotoxic effects, such as chromosomal aberrations or bad influences to ovulation and reproduction in experimental animals, etc.. In this study, tests for sister chromatid exchanges have been carried out on normal human lymphocytes in whole blood culture to add mercury chloride ($HgCl_2$) or methylmercury chloride ($CH_3\;HgCl$) for 72 hr. The results indicate the dose-dependent relationship between the frequencies of SCEs and the concentrations of $HgCl_2,\;CH_{3}HgCl$ and 5-bromo-2'-deoxyuridine (BrdU). Lymphocyte proliferation has depressed in the higher concentration of mercury.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.1341-1342
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• 2007

Poly-ether-sulphone (PES) 기판위에 열처리 공정을 거친 HgTe 나노입자를 이용하여 플렉시블 투명 박막 트랜지스터를 제작하였다. 활성층으로 사용된 HgTe 나노입자층은 UV/ozone 처리로 친수성화 된 PES 기판위에 스핀코팅으로 형성되었다. 제작된 박막 트랜지스터는 전형적인 p형 트랜지스터 특성을 보여주었으며, PES 기판에 스트레인을 가하지 않은 상태에서는 164의 전류점멸비와 1.6 $cm^{2}/Vs$ 의 전하 이동도가 계산되었고, PES 기판에 2.0%의 스트레인을 인가하였을 때에는 266의 전류점멸비와 1.0 $cm^2/Vs$ 의 전하 이동도가 계산되었다.

• Journal of Chest Surgery
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• 제20권1호
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• pp.30-38
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• 1987

Sixty-eight consecutive patients have been subjected to total corrective surgery of tetralogy of Fallot at the Hanyang University Hospital between August 1975 and December 1984. Of these, the pressure of chambers and great arteries were measured, before and immediately following an operation in 39 of the survived group and 11 of the expired group. The values of postoperative peak pressure were correlated with the outcome of the operation. The result are as followings; 1] Compared to the average peak pressure of right atrium in the survived group, 14.46*4.16 mmHg, that in the expired group, 19.36*8.19 mmHg, was significantly lower, 2] Compared to the average systolic pressure of right ventricle in the survived group, 56.72z16.37 mmHg, that in the expired group, 70.45*15.26 mmHg, was significantly lower. 3] Compared to the average systolic pressure of pulmonary artery in the survived group, 33.26*12.95 mmHg, that in the expired group, 37.55*11.63 mmHg, was higher. But the difference was not significant. 4] Compared to the average peak pressure of left atrium in the survived group, 17.41*6.90 mmHg, that in the expired group, 31.18*12.47 mmHg, was significantly higher. 5] Compared to the average systolic pressure of left ventricle in the survived group, 103.82~12.83 mmHg, that in the expired group, 90.55*20.02 mmHg, was significantly lower. 6] Compared to the average value of the right ventricle-pulmonary artery systolic pressure gradient [RV-PA] in the survived group, 24.95a15.44 mmHg, that in the expired group, 35.09*17.01 mmHg, was significantly higher. 7] Compared to the average value of the right ventricle to left ventricle systolic pressure ratio [RV/LV] in the survived group, 0.55*0.15, that in the expired group, 0.80a0.20, was significantly higher. 8] Compared to the average value of the pulmonary artery-left atrium peak pressure gradient [PA-LA] in 15.85x12.29 mmHg that in the expired group, 4.18x6.00 mmHg, was significantly lower. It is, therefore, suggested that in the operating room, PA-LA is as valuable as RV - PA, RV/LV in making important surgical decision and predicting the prognosis.

• 공업화학
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• 제10권5호
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• pp.677-681
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• 1999

휘발성 액체 혼합물의 분리공정에 필요한 증류탑 설계의 필수 요건인 기-액평형에 관한 연구로서 cyclohexanol-cyclohexanone 2성분계에 대한 감압하 즉 150, 300 및 500 mmHg에서의 기-액평형치를 측정하고, 이 측정치와 30, 100, 200, 395 및 750 mmHg에서의 이미 발표된 기-액평형치를 이용하여 비휘발도와 익조성의 관계로부터 cyclohexanol-cyclohexanone 2성분계의 기-액평형치를 추산하는 추산식을 구하고, 여기서 구한 추산치를 실측치 및 문헌치와 비교 검토하였다. 그 결과 적은 오차 범위에서 잘 일치함을 확인하였다.

• 한국대기환경학회지
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• 제24권6호
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• pp.693-703
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• 2008

The important source of the mercury in water-column is the influx of atmosphere mercury, via dry and wet deposition. In this study, wet deposition of mercury was estimated to be $14.56{\mu}g/m^2$ during 15 months at the Lake Soyang, which is a little higher than those observed in the several rural US Mercury Deposition Network (MDN) sites with similar precipitation depth. The mercury concentration in precipitation did not show a positive correlation with atmospheric RGM (reactive gaseous mercury) concentration, while maintaining good correlation with atmospheric $PM_{2.5}$ at Soyang Dam. This result suggests that the contribution of particulate Hg to the total Hg wet deposition should be more significant than that of RGM. In this study, both precipitation depth and precipitation type affected the amount of wet deposition and the concurrent mercury levels in precipitation. There was generally an inverse relationship between precipitation depth and Hg concentration in precipitation. Precipitation type was another factor that exerted controls on the Hg concentration in precipitation. As a result, the highest concentration of Hg was observed in snow, followed by in mixture (snow+rain) and in rain.