• Title/Summary/Keyword: $H_v-group$

Search Result 696, Processing Time 0.032 seconds

IGRINS Observations of Star Forming Clouds in NGC 6822 Hubble V

  • Pak, Soojong;Lee, Hye-In;Le, Huynh Anh N.;Lee, Sungho;Chung, Aeree;Kaplan, Kyle;Jaffe, Daniel T.
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.39 no.2
    • /
    • pp.92.2-92.2
    • /
    • 2014
  • NGC 6822 is a dwarf irregular galaxy in the Local Group. Unlike clouds in the Large Magellanic Cloud and the Small Magellanic Cloud, molecular clouds in NGC 6822 are not influenced by the Galactic tidal force. Therefore the star forming processes are only dictated by local conditions. Hubble V is the brightest of the several bright H II region complexes in NGC 6822. The core of Hubble V, surrounded by a molecular cloud complex, contains compact clusters of bright blue stars. During the commissioning runs of the new high-resolution near-infrared spectrometer, IGRINS (Immersion GRating near-INfrared Spectrometer), we observed Hubble V and detected many emission lines from the H II regions and from the photodissociation region at the interface between the ionized gas and the molecular cloud. In this presentation, we report preliminary results of the IGRINS observations. We discuss the implications of the observed lines ratios and kinematics for our understanding of the evolution of star forming molecular clouds.

  • PDF

A COMPARISON OF THE V4 STRAIN WITH THE CONVENTIONAL F1 AND M STRAIN OF NEWCASTLE DISEASE VACCINE IN RURAL BANGLADESH

  • Biswas, H.R.;Hoque, M.M.;Chowdhury, S.M.Z.H.;Oxley, M.E.;Rahman, M.M.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.9 no.2
    • /
    • pp.231-235
    • /
    • 1996
  • Bangladeshi indigenous chickens of mixed ages vaccinated twice at a three week interval with either conventional vaccines-$F_1$ (ocular) and M (mukteswar, Intramuscular), or heat resistant $V_4$ vaccine administered by either the ocular or oral routes, all showed satisfactory hemagglutination inhibition antibody (HI) responses and protection against Newcastle Disease (NCD) challenge persisting for four months. The antibody response to $F_1$ and M was higher than for $V_4$, which was similar whether administered by the ocular or oral routes. All vaccinated treatments have a significant level of protection compare to the control group (p<0.01). No significant difference (p>0.05) in the protection against controlled challenge with virulent NCD virus was found between vaccinated groups.

Comparison of pretreatment gabapentin and pregabalin to control postoperative endodontic pain - a double-blind, randomized clinical trial

  • Verma, Jayeeta;Verma, Sidharth;Margasahayam, Sumanthini V
    • Journal of Dental Anesthesia and Pain Medicine
    • /
    • v.22 no.5
    • /
    • pp.377-385
    • /
    • 2022
  • Background: Postoperative endodontic pain is an enigma for the dentist. This study aimed to evaluate the analgesic effect of 300 mg gabapentin or 75 mg pregabalin in reducing postoperative endodontic pain compared with a placebo. Methods: Ninety patients who needed root canal treatment with an initial numerical rating scale (NRS) pain score of > 4 (T0) were randomly divided into three groups (n=30). Patients were then administered either 300 mg gabapentin (group A), 75 mg pregabalin (group B), or a placebo (group C) 30 min prior to the start of endodontic treatment. A single operator performed single-visit endodontics, and pain was evaluated immediately after endodontic treatment (T1) and at 4 h (T2), 8 h (T3), 12 h (T4), 24 h (T5), 48 h (T6), and 72 h (T7) using the NRS. Ibuprofen/paracetamol (400 mg/325 mg) was administered as a rescue dose if needed. Results: Pregabalin performed significantly better when compared with gabapentin at all time points except at 72 h after treatment (P=0.170). The placebo group showed significantly higher pain scores than the other two groups. The percentage of pain relief was maximum for pregabalin (92.1%), followed by gabapentin (87.6%) and placebo (69.1%) at 72 h after treatment completion. Conclusion: This study showed that pretreatment with a single dose of pregabalin and gabapentin both had greater analgesic effects than a placebo. They can be effectively used to reduce postoperative endodontic pain.

HOLONOMY DISPLACEMENTS IN THE HOPF BUNDLES OVER $\mathcal{C}$Hn AND THE COMPLEX HEISENBERG GROUPS

  • Choi, Young-Gi;Lee, Kyung-Bai
    • Journal of the Korean Mathematical Society
    • /
    • v.49 no.4
    • /
    • pp.733-743
    • /
    • 2012
  • For the "Hopf bundle" $S^1{\rightarrow}S^{2n,1}{\rightarrow}\mathbb{C}H^n$, horizontal lifts of simple closed curves are studied. Let ${\gamma}$ be a piecewise smooth, simple closed curve on a complete totally geodesic surface $S$ in the base space. Then the holonomy displacement along ${\gamma}$ is given by $$V({\gamma})=e^{{\lambda}A({\gamma})i}$$ where $A({\gamma})$ is the area of the region on the surface $S$ surrounded by ${\gamma}$; ${\lambda}=1/2$ or 0 depending on whether $S$ is a complex submanifold or not. We also carry out a similar investigation for the complex Heisenberg group $\mathbb{R}{\rightarrow}\mathcal{H}^{2n+1}{\rightarrow}\mathbb{C}^n$.

The Solvent-Independent Structure of Piroxicam (피록시캄의 용매 비의존 결정구조)

  • Kim, Bong-Hee;Suh, Il-Hwan;Jhee, Ok-In;Suh, Jong-Myung;Suh, Jung-Jin
    • Journal of Pharmaceutical Investigation
    • /
    • v.18 no.4
    • /
    • pp.209-215
    • /
    • 1988
  • The three-dimensional structures of piroxicam crystallized from two different solvents, toluene and toluene/hexane mixture respectively, are proved identical: $C_{15}H_{13}N_3O_4S,\;M\;=\;331.35$, monoclinic, a = 7.128(1), b = 15.146(2), c = 13.956(2) ${\AA},\;{\beta}=\;97.33(1)^{\circ},\;V\;=\;1494.37{\AA}^{3},\;Dx\;=\;1.472\;g/cm^{3},\;Z\;=\;4,\;space\;group\;P2_{1}/c,\;Mo\;K{\alpha}(\lambda=\;0.71073\;{\AA})$, F(000) = 688, T = 295 K, R = 0.0611 for 1993 unique observed reflections. The thiazine ring exhibits a half chair conformation. An amide group is involved in an intramolecular hydrogen bond to the hydroxy group, O(17)-H(17)${\cdots}O(15){\AA}$. The molecule is planar within 2 ${\AA}$ with the interplanar angle $127.9(4)^{\circ}$ between pyridine and benzene rings. A molecular chain parallel to [011] is formed by two intermolecular hydrogen bonds N(16)-H(6)${\cdots}O(11)$ and C(6)-H(6)${\cdots}O(11)$, and the molecular chains are held together by van der Waals forces.

  • PDF

Synthesis, Characterization and Antimicrobial Activities of Hydrazone Ligands Derived from 2-(phenylamino)acetohydrazide and Their Metal Complexes (2-(Phenylamino)acetohydrazide로부터 유도된 Hydrzone 리간드와 그들의 착물의 합성, 특성 및 항균활성)

  • EL-Saied, F.A.;Shakdofa, M.M.E.;Al-Hakimi, A.N.
    • Journal of the Korean Chemical Society
    • /
    • v.55 no.3
    • /
    • pp.444-453
    • /
    • 2011
  • VO(II), ZrO(II), Hf(IV), $UO_2$(II), Sn(II), V(V)$O_3$, Ru(III), Cd(II), Ho(III) and Yb(III) complexes of N'-(2-hydroxybenzyl)-2-(phenylamino)acetohydrazide ($H_2L^1$, 1) and N'-((3-hydroxy-naphthalen-2-yl)methylene)-2-(phenylamino)-acetohydrazide ($H_2L^2$, 13) have been synthesized and characterized by elemental analyses, $^1H$ NMR, IR, UV-Vis, conductance, thermal analyses (DTA and TG). The spectral data showed that the ligands behave as neutral bidentate, monobasic bidentate, monobasic tridentate or bibasic tridentate ligand bonded to the metal ions through the azomethine nitrogen atoms, phenolic hydroxyl group in protonated or deprotonated form and enolic or ketonic carbonyl group. The ligands and their metal complexes exhibit higher antifungal and antibacterial inhibitory effects than parent ligands and the solution of metal ions. Most of metal complexes exhibit higher antifungal activity than standard antifungal drug (amphotricene B). It is also clear that the ligands and their metal complexes have higher antifungal activity than antibacterial activity.

Effect of Increased Intracellular pH by HMA on the Cytotoxicity of Combined Treatment of Hyperthermia and Chemotherapy (HMA의 세포내 산도증가가 온열과 항암화학 치료의 세포독성에 미치는 효과)

  • Hur, Won-Joo;Song, Chang-Won
    • Radiation Oncology Journal
    • /
    • v.13 no.2
    • /
    • pp.121-128
    • /
    • 1995
  • Purpose: The enhanced cytotoxic effect of combined treatment of hyper-thermia and chemotherapy by increasing intracellular acidity with HMA was investigated. Materials and Methods: FSall tumor cells were injected on the hindlegs of female $C_3H$ mice. When the tumor volume reached about 200mm3, experiments were performed on the groups classified as follows: Group I :Control, Group II : Melphalan alone (2.5mg/kg, 5mg/kg, 10mg/kg, 15mg/kg), Group III : Heat alone $(42.5^{\cdot}C$ for 1 hour) Group IV : Melphalan + Heat $(42.5^{\cdot}C$ for 1 hour), Group V : HMA(10mg/kg) + Melphalan(5.0mg/kg) + Heat$(42.5^{\cdot}C$ for 1hour). Each group included 8-12 mice on each experiment HMA (3-amino-6-chloro-5-(1-homopiperidyl )-N-(diaminomethylene) -c-pyrazinecarboxamide), an analog of amiloride which increases intracellular pH(pHi) was dissolved in dimethyl sulfoxide (DMS) and injected into the tumor-bearing mice through the tail vein. 10mg/kg of HMA and each dose of melphalan were injected into peritoneum of the tumor-bearing mice 30 minutes before heating. Tumor growth delay was calculated when the tumor volme reached at $1500mm^3$ Excision assay was performed on each group and repeated 2-4 times. Results : Tumor growth delay of each experimental groups at $1500mm^3$ were 9, 10, 13 and 19 days respectively. In vivo-in vitro excision assay using FSall tumor cells, the cytotoxicity of each experimental groups was $1.2{\times}10^7,\;1{\times}10^7,\;6{\times}10^6,\;1.7{\times}10^6\;and\;1{\times}10^5$ clonogenic cells/gm respectively When HMA was added to the combined treatment of heat and .chemotherapy, the tumor growth was delayed more than combined treatment without HMA i.e., 6 days tumor growth delay at $1500mm^3$ of tumor volume. Conclusion: The combined effect of cytotoxicity by heat and chemotherapy can be much more enhanced by HMA.

  • PDF

Experimental Analysis in the Reversible and Irreversible Cerebral Ischemic Models in the Rat (백서의 가역성 및 비가역성 뇌허혈 모형의 실험적 고찰)

  • Song, Kwang Chul;Choi, Byung Yon;Kim, Seong Ho;Bae, Jang Ho;Kim, Oh Lyong;Cho, Soo Ho
    • Journal of Korean Neurosurgical Society
    • /
    • v.29 no.7
    • /
    • pp.853-860
    • /
    • 2000
  • Objective : The purpose of our experimental study was to analysis the advantages and disadvantages in the reversible and irreversible cerebral ischemic models with rats by staining with Neutral Red(NR) solusion, 2% 2,3,5-triphenyltetrazolium chloride(TTC) and Hematoxylin & Eosin(H & E). Methods : We have measured the range of cerebral infarction in the rat to get a suitable ischemic model along the object of study with and without craniectomy. With craniectomy, 9 rats were sacrificed for irreversible cerebral ischemic model by means of ligation at proximal(group I) and distal(group II), and coagulation at proximal(group III) middle cerebral artery. Also, 6 rats were sacrificed for irreversible(group IV) and reversible(group V) cerebral ischemic model using nylon thread without craniectomy. The sizes of infarction were measured by staining the coronal sections of the brain with NR solusion, TTC and H & E. Results : There are no difference of physiological parameters comparing the each group. Cerebral infarction was not observed in group II, but it's volume was largest in group IV. Disadvantages of craniectomy group(I, II, III) are the long duration of operation and cortical damage by procedure. It's advantage is confirmation of the middle cerebral artery occlusion and cessation of blood flow through the operative microscope. In case of ischemic models using nylon thread (group IV, V), it is hard to identify the interruption or recirculation of blood flow through the middle cerebral artery, but the advantage is the simplicity of operative technique which reduces the operation time and minimizes the cerebral damage due to craniectomy. Therefore, it seems important to set up the reversible and irreversible ischemic models by carefully considering advantages and disadvantages listed above. Conclusion : TTC staining seems to be effective since it reflects the histological damage sufficiently and quickly. It is hoped that researches focused on ischemic penumbra, which became popular recently, will be further carried on with use of NR staining, optical microscope and electron microscope.

  • PDF

Cinnamic Acid Derivatives IV, The Kinetics and Mechanism of the Hydrolysis of Cinnamylidene aniline Derivatives (신남산 유도체 Ⅳ, Cinnamylidene anilin 유도체의 가수분해 반응에 대한 메카니즘과 그 반응속도론적 연구)

  • Lee, Gi-Chang;Park, Su-In;Hwang, Yong-Hyeon;Lee, Gwang-Il;Choe, Bong-Jong;Jeong, Deok-Chae
    • Journal of the Korean Applied Science and Technology
    • /
    • v.8 no.1
    • /
    • pp.1-7
    • /
    • 1991
  • The kinetic of hydrolysis for cinnamylidene aniline derivatives has been investigated by ultraviolet spectrophotometry in 20% (v/v) dioxane - $H_2O$ at $25^{\circ}C$. A rate equation which can be applied over wide pH range was obtained. The substituent effects on cinnamylidene aniline derivatives were studied and the hydrolysis was facilitated by electron attracting group. Final products of the hydrolysis were cinnamaldehyde and aniline. From the rate equation, substituent effect and final products, the hydrolysis of cinnamylidene aniline derivatives was initiated by the neutral molecule of $H_2O$ which does not dissociate at below pH 9.0${\sim}$12.0, but proceeded by the hydrogen ion at above pH 5.0${\sim}$9.0.

Synthesis and Crystal Structure of the Cadmium(II) Complex with Thiocyanate and 1,2-Diaminocyclohexane Ligands (Thiocyanat 및 1,2-Diaminocyclohexane 리간드로 구성된 카드뮴(II) 착물의 합성 및 결정구조)

  • 김인회;서승욱;김종혁;김진규;서일환
    • Korean Journal of Crystallography
    • /
    • v.12 no.4
    • /
    • pp.207-211
    • /
    • 2001
  • The crystal structure of the title complex, Cd(SCN)₂{CH/sub 6/H/sub 10/(NH₂)₂}₂(1) has been analyzed by X-ray single crystallography. The complex 1 crystallizes in the monoclinic system P2₁/ space group with a=11.842(2), b=7.926(2), c=11.291(2) Å, β=106.73(3)°V=1014.8(4)Ų, Z=2, R₁=0.0518 and ωR₂=0.1315 for 1775 independent reflections. The central Cd(II) atom of this com-plex has a slightly distorted octahedral coordination geometry, with the 1,2-Diaminocyclohexane ligands functioning as an N,N'-bidentate and the thiocyanate ligands bonding through the sulfur atom in a trans arrangement.

  • PDF