• Archives of Pharmacal Research
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• v.18 no.1
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• pp.1-7
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• 1995

IY-80843, N[2-(2-methoxyphenyl)ethyl]-N'-[4-(lmidazole-4-yl)phenyl] formamidine, is a new potent $H_2-receptor$ anagonist. The potential secondary pharmacologic effects of this agent, on the central nervous and cardiovascular systems were studied. IY-80843 caused ptosis, suppression of locomotion, hypotehrmia, prolongation of sleeping time and hypotensive effects in mice, rats and dogs. These results suggest that IY-80843 affects the funcition of the central nervous and cardiovascular systems in a dose-dependent manner.

• Journal of Nutrition and Health
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• v.12 no.1
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• pp.59-68
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• 1979

This work was carried out to detect the enterobacterial contamination in summer kimchies and their antagonis tic activity with lactic acid bacteria during kimchi fermentation. And obtained results were as in the followings. 1) Severe cases of enterobactrial contamination were found in every kimchi material and in the first step of summer kimchi fermention. 2) Some pathogenic or food poisonous strain of Salmonellaspp. was identified among the contaminated enterobacteria. 3) Pathogenic strains of Salmonella typhi, Shigella flexneri or E. coli which were added to kimchi fermention, were contineously detected for 10days at the temperature of $10^{\circ}C$. Food poisonous strain of Vibrio parahemolyticus was more resistant than the above stains in the kimchi fermentation. 4) And in summer condition(over $30^{\circ}C$) the added pathogenic strains of enterobacteria were also detected for 2 day at pH of 4.5 kimchi fermentation. 5) The antagonistic activity of enterobacteria in lactate buffer solution of pH 4.8 was more stron than that in the kimchi fermentation at $30^{\circ}C$ of summer condition. 6) According to the above results, sanitary washing processes for every kind of kimchi material (vegitables) are required to reduce the enterobacterial concentration which is usually contaminated. And some fermentation period is also required to avoid the possible kimchi food poisoning.

• Journal of The Korean Society of Grassland and Forage Science
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• v.9 no.1
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• pp.26-33
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• 1989

This pot experiments were conducted to find out the optimal fertilization ratios of the N:S:P anions and K:Ca:Mg cations of major nutrients in an orchardgrass/ladino clover mixed sward. The optimum ratios in equivalent basis were computed by the Homes systematic variations technique. The soil samples were collected from the newly reclaimed soils, which are located on colluvial hilly area with a good consideration for the hilly pasture development. The results were summarized as follows; 1, the optimum fertilization ratios of major nutrients for the high yields by the forage species in a mixed sward were obtained (Table 4 in detail); N:S:P = 3:l: 1 and K:Ca:Mg = 1:l: 1 for grass and grass plus legume, and N:S:P = 1:6:43 and K:Ca:Mg = 1: 3: 1 for legume in general. 2. The yield increases from the systematic variations in this mixed sward were laid in following order; N > P >S-group and K >Mg >Ca-group for grass and grass plus legume, and P >S >N-group and Ca >Mg > K-group for legume. Especially, the yields were greatly increased at the N-group for grass, and at the Pand Ca-groups for legume. 3. Soil pH-value was descreased at the Sgroup, and somewhat increased at the Ca- and Mg-groups. The content of available $P_2O_5$, CEC and base saturation were greatest with the Ca-group. 4. At the N-group, the N-contents were highest and the P-contents were lowest in grass and grass plus legume, which resulted in the highest Ca/P ratio of 2.15 among the anion groups. Whereas the highest Ca/P ratio of 9.20 in legume was obtained at the Ca-group. Legume showed in general higher Ca/P ratio and lower K/(Ca+Mg) ratio than these in grass. 5 . There were differences in the effects of systematic variations of major nutrients on the dry matter yields and the mineral yields. The optimum fertilization ratios of anions and cations for the high mineral yields were obtained (Table E), which showed differences comparing with the ratios for the high dry matter yields. The antagonis between the cations K and Mg was known from the point of mineral yields of mixed forages.