• Title/Summary/Keyword: $GT_1$

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Effect of Korean Traditional Tea Materials on Minerals Content and Histological Changes in Pb-Administered Rats (전통음료 소재가 납투여한 흰쥐의 체내 무기질 함량 및 간과 신장조직의 헝태학적 변화에 미치는 영향)

  • 조수영;김명주;이미경;박은미;장주연;최정목;김덕진
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.311-317
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    • 2004
  • This study was designed to investigate the effect of Korean traditional tea materials on lead (Pb) accumulation and histological changes in Pb-administered rats. Male rats were divided into six groups: a normal, Pb, and Pb-water extract of Korean traditional tea materials (green tea: GT, persimmon leaf: PL, safflower seed: SS, Eucommia ulmoides: EU) groups. Pb (25 mg/kg BW) was orally administered once a day for 4 weeks. The extract of GT, PL, SS, and EU were administered based on 1.26 g of raw traditional tea materials/kg Bw/day. Pb contents of serum and liver were significantly higher in the Pb group than in the normal group. However the water extracts of GT, PL, SS, and EU administration lowered Pb contents of serum and liver in the Pb-administered rats, respectively. Serum Zn content was significantly higher in the Pb group than in the normal group, whereas, Cu and Fe contents were lower in the Pb group. Hepatic Ca content was significantly lower in the Pb group compared to the normal group. In the present study, water extract of Korean traditional tea materials administration effectively improved Cu and Fe contents of serum and liver. Infiltration of the local inflammation was found in Pb group, whereas water extracts of Korean traditional tea materials administration attenuated histological changes of tissues.

Effect of Vinegar Made with Hydroponic-cultured Panax ginseng C. A. Meyer on Body Weight and Lipid Metabolism in High-Fat Diet-Fed Mice (수경재배 인삼으로 제조한 식초가 고지방 식이를 섭취한 마우스의 체중 및 지질대사에 미치는 영향)

  • Oh, Young-Joo;Kwon, Seung-Hyuk;Choi, Kum Boo;Kim, Tae-Seok;Yeo, Ik-Hyun
    • Korean Journal of Food Science and Technology
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    • v.46 no.6
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    • pp.743-749
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    • 2014
  • The aim of this study was to develop hydroponic-cultured ginseng vinegar (HGV) containing ginsenoside Rg2 in order to its anti-obesity and anti-hyperlipidemic effects in C57BL/6J mice. HGV was prepared by two-stage fermentation. The ginsenoside Rg2 contained in acetic acid-fermented HGV increased by 4.0 times compared to that in pre-fermented HGV. To measure the anti-obesity effect of HGV, thirty two mice were randomly divided into four groups: normal diet group (ND), high-fat diet group (HFD), high-fat diet-supplemented with HGV group (HGV), and high-fat diet-supplemented with green tea extract group (GT). Body weight, fat weight, and liver weight decreased in the HGV group. The HGV group also showed lower plasma levels of low-density lipoprotein (LDL)-cholesterol and triglycerides, and higher levels of high-density lipoprotein (HDL)-cholesterol compared to the corresponding levels in the HFD group. Furthermore, there were significant decreases in plasma aspartase aminotransferase (AST) and alanine aminotransferase (ALT) levels in the HGV group compared to the corresponding levels in the HFD group. These results suggest that HGV can be used as an anti-obesity therapeutic agent or functional ingredient.

A Effects of Natural Gas-Diesel/Hi-sene Dual Fuel Operation on Performance of a Heavy-Duty Diesel engine for Power Generation (발전용 대형 디젤 엔진의 천연가스-디젤/부생유(Hi-sene) 혼합연소 시 엔진 성능변화에 미치는 영향)

  • Cho, Jungkeun;Park, Sangjun;Song, Soonho
    • Journal of Energy Engineering
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    • v.25 no.1
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    • pp.122-130
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    • 2016
  • This study is a numerical study using commercial simulation program GT-Power on 1.5MW diesel engine for power generation. Performance comparison has done for diesel operation with dual fuel operation for different engine load(50%, 75%, 100%) using the target engine model with additional gas injection system. Effect of using Hi-sene, which is actually being used in island area, instead of diesel was also studied. As a result, under 60% natural gas with diesel condition, BSFC was increased by 32% without modifying system. There was almost no change for natural gas/Hi-sene condition compared with natural gas/diesel condition. Decrease of burned fuel fraction was the main reason of these phenomena. After optimizing system, BSFC was improved by 2%.

Development of a High-Resolution Multi-Locus Microsatellite Typing Method for Colletotrichum gloeosporioides

  • Mehta, Nikita;Hagen, Ferry;Aamir, Sadaf;Singh, Sanjay K.;Baghela, Abhishek
    • Mycobiology
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    • v.45 no.4
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    • pp.401-408
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    • 2017
  • Colletotrichum gloeosporioides is an economically important fungal pathogen causing substantial yield losses indifferent host plants. To understand the genetic diversity and molecular epidemiology of this fungus, we have developed a novel, high-resolution multi-locus microsatellite typing (MLMT) method. Bioinformatic analysis of C. gloeosporioides unannotated genome sequence yielded eight potential microsatellite loci, of which five, CG1 $(GT)_n$, CG2 $(GT1)_n$, CG3 $(TC)_n$, CG4 $(CT)_n$, and CG5 $(CT1)_n$ were selected for further study based on their universal amplification potential, reproducibility, and repeat number polymorphism. The selected microsatellites were used to analyze 31 strains of C. gloeosporioides isolated from 20 different host plants from India. All microsatellite loci were found to be polymorphic, and the approximate fragment sizes of microsatellite loci CG1, CG2, CG3, CG4, and CG5 were in ranges of 213-241, 197-227, 231-265, 209-275, and 132-188, respectively. Among the 31 isolates, 55 different genotypes were identified. The Simpson's index of diversity (D) values for the individual locus ranged from 0.79 to 0.92, with the D value of all combined five microsatellite loci being 0.99. Microsatellite data analysis revealed that isolates from Ocimum sanctum, Capsicum annuum (chili pepper), and Mangifera indica (mango) formed distinct clusters, therefore exhibited some level of correlation between certain genotypes and host. The developed MLMT method would be a powerful tool for studying the genetic diversity and any possible genotype-host correlation in C. gloeosporioides.

Strategic Use of QTL Mapping to Improve the Palatability of Rice

  • Yoon-Hee Jang;Jae-Ryoung Park;Eun-Gyeong Kim;Kyung-Min Kim
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.286-286
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    • 2022
  • The properties of starch play an important role in determining the palatability of rice. In addition, the gelatinization temperature (GT) of rice starch is an important factor in determining the quality of rice because it is related to the cooking time and texture of rice. For the development of high-quality rice, it is important to understand the genetic basis of palatability-related traits, and QTL analysis is an effective method to explain the genetic basis of variation in complex traits. QTL mapping related to alkali digestion value (ADV) of brown and milled rice was performed using the 120 Cheongcheong/Nagdong double haploid (CNDH) line. As a result, 12 QTLs related to ADV were detected, and 20 candidate genes were selected from the RM588-RM1163 region of chromosome 6 through screening by gene function analysis. The comparison of the relative expression level of candidate genes showed that OsSS1q6 is highly expressed in CNDH lines with high ADV in both brown rice and milled rice. In addition, OsSS1q6 has high homology with starch synthase 1 protein, and interact with various starch biosynthesis-related proteins, such as GBSSII, SBE, and APL. Therefore, we suggest that OsSS1q6 identified through QTL mapping could be one of the various genes involved in the GT of rice by regulating starch biosynthesis. This study can be used as basic data for breeding high-quality rice and provides a new genetic resource that can increase the palatability of rice.

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A study on Group Technology using the multi-job machine (다작업이 가능한 기계하의 GT에 관한 연구)

  • 전용덕
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.16 no.27
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    • pp.83-89
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    • 1993
  • In order to model the Group Technology Problem three formulations are used, that is, generally the following formulations are used: (1) Matrix formulation, (2) Mathematical programming formulation, (3) Graph formulation. In the case of Matrix formulation, it is difficult to discribe the situation using the multi-job machine. But this paper proposed the model of Group Technology using the multi-job machin, taking the method of making practical application of principle of similarity coefficient.

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1-Dimensional Performance Analysis of Diesel Engine (디젤엔진의 일차원 성능해석)

  • Park, Sung-Young
    • Proceedings of the KAIS Fall Conference
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    • 2012.05b
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    • pp.671-673
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    • 2012
  • 본 연구에서는 상용 엔진 해석프로그램인 GT-Power를 이용하여 디젤엔진의 성능을 개선 개발을 위한 일차원 성능해석 모델을 개발하였다. 개발된 일차원 엔진 성능모델을 통하여 엔진의 출력, 토크 및 연비등을 검토하였다. 향후 터보챠져를 장착한 엔진개발에 사용이 가능하도록 터보매칭을 할 수 있는 모델을 추가하였으며, 향후 디젤엔진의 실험결과와 비교를 통하여 엔진 모델을 지속적으로 보완할 예정이다.

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Global Carbon Budget Changes under RCP Scenarios in HadGEM2-CC (HadGEM-CC 모델의 RCP 시나리오에 따른 전지구 탄소수지 변화 전망)

  • Heo, Tae-Kyung;Boo, Kyung-On;Shim, Sungbo;Hong, Jinkyu;Hong, Je-Woo
    • Atmosphere
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    • v.25 no.1
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    • pp.85-97
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    • 2015
  • This study is to investigate future changes in carbon cycle using the HadGEM2-Carbon Cycle simulations driven by $CO_2$ emissions. For experiment, global carbon budget is integrated from the two (8.5/2.6) representative concentration pathways (RCPs) for the period of 1860~2100 by Hadley Centre Global Environmental Model, version 2, Carbon Cycle (Had-GEM2-CC). From 1985 to 2005, total cumulative $CO_2$ amount of anthropogenic emission prescribed as 156 GtC. The amount matches to the observed estimates (CDIAC) over the same period (136 GtC). As $CO_2$ emissions into the atmosphere increase, the similar increasing tendency is found in the simulated atmospheric $CO_2$ concentration and temperature. Atmospheric $CO_2$ concentration in the simulation is projected to be 430 ppm for RCP 2.6 at the end of the twenty-first century and as high as 931 ppm for RCP 8.5. Simulated global mean temperature is expected to rise by $1.6^{\circ}C$ and $3.5^{\circ}C$ for RCP 2.6 and 8.5, respectively. Land and ocean carbon uptakes also increase in proportion to the $CO_2$ emissions of RCPs. The fractions of the amount of $CO_2$ stored in atmosphere, land, and ocean are different in RCP 8.5 and 2.6. Further study is needed for reducing the simulation uncertainty based on multiple model simulations.

STAT6 Gene Polymorphisms in Allergic Rhinitis

  • Kim, Jeong Joong;Kim, Min Su;Lee, Jung Hun;Choi, Tae Wook;Choi, Sang Heon;Lee, Jae Hoon;Chung, Hun Taeg
    • Genomics & Informatics
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    • v.2 no.3
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    • pp.126-130
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    • 2004
  • T helper-type 2 cytokines, such as IL-4 and IL-13, may play a central role in allergic diseases. The protein known as signal transducers and activators of transcription 6 (STAT6) is a key transcription factor involved in both IL-4- and -13-mediated biological responses. Two polymorphisms of the STAT 6 gene (exon 1 and G2964A variant) have been found. We investigated whether these STAT6 gene polymorph isms were associated with allergic rhinitis. Blood samples for genetic analysis were obtained from 285 individuals with allergic rhinitis and from 271 healthy subjects without atopic disease. The G2964A variant of the STAT6 gene was genotyped using PCR-RFLP analysis. The GT repeat polymorphism in exon 1 of the STAT6 gene was genotyped by fragment analysis. There was no association between the 2964A variant and GT repeat polymorphism in exon 1 of the STAT6 and allergic rhinitis in a Korean population (both p > 0.05). Our results suggest that a combination of STAT6 gene polymorphisms is not a useful marker for predicting allergic rhinitis.

Effects of Swirl and Combustion Parameters on the Performance and Emission in a Turbocharged D.1. Diesel Engine (선회유동 및 연소인자가 터보과급 디젤엔진의 성능 및 배기가스특성에 미치는 영향)

  • 윤준규;차경옥
    • Journal of Energy Engineering
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    • v.11 no.2
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    • pp.90-98
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    • 2002
  • The effects of swirl and combustion parameters on the performance and emission in a turbo-charged D.I. diesel engine of the displacement 9.4L were studied experimentally in this paper. Generally the swirl in the combustion process of diesel engine promotes mixing of the injection fuel and the intake air. It is a major factor to improve the engine performance because the fuel consumption and NO$_{x}$ is trade-off according to the high temperature and high pressure of combustion gas in a turbocharged D.I. diesel engine, it's necessary to thinking over the intake and exhaust system, the design of combustion bowl and so on. In order to choose a turbocharger of appropriate capacity. As a result of steady flow test, when the swirl ratio is increased, the mean flow coefficient is decreased, whereas the gulf factor is increased. Also, through engine test its can be expected to meet performance and emissions by optimizing the main parameter's; the swirl ratio is 2.43, injection timing is BTDC 13$^{\circ}$ CA, compression ratio is 16, combustion bowl is re-entrant 5$^{\circ}$, nozzle hole diameter is $\Phi$0.28*6, turbocharger is GT40 model which are compressor A/R 0.58 and turbine A/R 1.19.