• Toxicological Research
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• 제14권3호
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• pp.365-370
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• 1998

To evaluate the renal toxicity of the antitumor agent, p-{N,N,-Bis(2-chloroethyl)amino}-4-phenyl acetyl-amino-2,6-piperidinedione(CK-15), rats were treated with CK-15 (acute: 50mg/kg. i.p., single and subacute: 5mg/kg, i.p., daily for 7 days). The changes in the body weight, water consumption, kidney weights and urine volume after and during the treatment were observed. The concentrations of urinary creatinine and portein, the activities of N-acetyl-${\beta}$-D-glucosaminidase (NAG), alanine aminopeptidase (AAP), ${\gamma}$-glutamyl transpeptidase (${\gamma}$-GT) and lactate dehydrogenase (LDH) in 24hr urine were also determined. The body weight, water consumption, and urine volume were decreased after the acute and subacute administration. However the weights of kidney were not changed after the treatments. The excretion of creatinine was significantly decreased 1 day after acute administration but, returned to the control value. In subactute administration, the excretion of creatinine was gradually decreased. However, the protein excretion did not changed in both treatment. Those indicate that CK-15 might decrease the metabolic rate of muscle. THe urinary activities of NAG, AAP, ${\gamma}$-GT, and LDH were significantly affected bythe drug treatment. The urinary activities of NAG, AAP and ${\gamma}$-GT were significantly increased 1 day after the acute administration and then returned to the control value. However, the urinary activities of LDH were not changed in acute treatment. In subacute treatment, although the urinary activities of NAG were not changed, those of AAP and ${\gamma}$-GT were significantly increased 2.3 times at 3 days during the subacute administration. Also the urinary activities of LDH were significantly increased at 7 day after the administration. These results indicate that the high and subacute administration might induce a damage in the kidney cells. Furthermore the present results suggest that the toxic effects of CK-15 might be due to the accumulation of the metabolites.

• 한국작물학회지
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• 제33권1호
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• pp.87-96
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• 1988

재배환경과 품질이 크게 상이한 한국의 만기작과 조기작, 그리이스 관행 재배에서의 생육환경, 잎담배의 화학성분 변화와 품질과의 관계를 분석한 결과, 1. 생육중 강우량은 한국의 만기작＆gt; 조기작＆gt; 그리이스작 순으로 적고, 일조시수는 강우량의 역순이었으며, 조기작은 만기작에 비해 이식후 30∼80일 기간중 강우량이 60% 적고, 일조시수는 20% 많았다. 2. 그리이스작은 한국 재배엽에 비하여 전질소, 니코틴, 석유에텔 추출물함량이 현저히 높았다. 그리이스작＆gt;조기작＆gt;만기작 순으로 휘발성 유기산, 정유성분 중성부의 함량이 높고 품질이 좋았으며, 조기작은 만기작보다 회분함량과 pH가 크게 낮았다. 3. 건조엽의 품질과 석유에텔추출물, 휘발성 유기산, 전질소함량은 정의 상관, 회분함량은 부의 상관을 보였다. 4. 품질평가를 위한 지수로는 총 휘발성 유기산(mg/100g), (equation omitted) 접합도가 높았다.

• 한국항해항만학회지
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• 제34권6호
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• pp.405-415
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• 2010

본 논문에서는 현재 건설 중인 목포 대교와 통항 선박 사이에 발생 가능한 충돌 위기를 평가하기 위한 선박-교량 충돌 모델(Real-Time Bridge-Vessel Collision Model, RT-BVCM)을 제안하였다. RT-BVCM의 수학 모델은, 항행환경으로 선박이 이탈하게 되는 원인 확률과, 선박의 크기와 교량 구조로 인한 기하학적 확률, 선박의 충돌 침로와 정지거리에 기인한 충돌 회피 실패 확률 등으로 구성하였다. 그리고 이러한 확률적인 수학 모델은 1부터 5까지의 위기수준을 갖는 위기지수로 나타냈다. 본 연구에서 제안한 RT-BVCM은 기존 AASHTO(American Association of State Highway and Transportation Officials)에 제시된 선박-교량 충돌 모델과 달리, 충돌 회피를 위한 충분한 시간을 확보할 수 있는 장점이 있다. 3,000 GT와 10,000 GT 실험 선박에 다양한 항행환경을 적용한 시뮬레이션 실험 결과, 제안한 모델이 목포 대교와 통항 선박 사이의 충돌위기 평가 모델로 타당함을 확인하였다.

• 한국통신학회논문지
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• 제41권1호
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• pp.23-36
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• 2016

본 논문에서 제안하는 새로운 유형의 상향링크 OFDM-CDMA 기법은 ZCZ(Zero Correlation Zone) 부호와 블록 확산 기법을 함께 이용하여 사용자간의 넓은 접속시간 동기오차 허용범위를 가진다. 또한, 제안하는 기법은 OFDM 신호에 보호구간을 삽입하지 않아 주파수 효율을 최대화 한다. 넓은 사용자간 접속시간 동기오차 허용범위를 가지려면 보호구간의 길이를 늘여야 하는 기존 기법과 달리, 본 논문에서 제안하는 기법은 보호구간을 삽입하지 않아도 아주 넓은 사용자간 접속시간 동기오차 허용범위를 가진다. 제안하는 보호구간이 없는 상향링크 OFDM-CDMA 기법은 다중경로 페이딩 환경에서 수신단의 역확산 과정을 통해 모든 사용자간 간섭이 사라지는 특성을 가진다. 더욱이, 제안하는 기법은 복수개의 OFDM 심볼 길이만큼의 사용자간 동기오차 환경에서도 모든 사용자간 간섭이 없다. 보호구간이 없기 때문에 자기 신호의 부반송파간 간섭은 존재하지만, 제안하는 블록 확산 방식으로 인한 블록의 첫 번째 심볼이 ISI(Inter Symbol Interference)가 없는 특성을 이용하여 간단한 SIC(Successive Interference Cancellation)를 통해 첫 번째 이후 심볼의 간섭도 효과적으로 억제할 수 있다.

• 한국IT서비스학회지
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• 제19권4호
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• pp.63-84
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• 2020

With the recent announcement of the WCAG2.2 Work Draft of the W3C, revision of the WCAG2.2 guidelines will be made soon. Consequently, the revision of KWCAG2.1 in response to changes in the domestic and international environment of web accessibility is urgent. The revision primarily involves development and selection of web accessibility evaluation items. In this study, the efficient procedures and useful methodologies for developing and selecting the evaluation items are to be presented. FGI (Focus Group Interview) has been devised to reflect every stakeholders opinion fairly. GT (Group Technology) has been applied to expedite the revision processes particularly in the FGI. QFD (Quality Function Deployment) method plays an important role in investigating the relationship between evaluation items and its characteristics, and in analyzing the importance and priorities of each item. This study proposes 5 principles, 17 guidelines and 39 evaluation items which can be used for the revision of KWCAG 2.1. This study is expected to be of great help in establishing the KWCAG 2.2 in the near future.

• 사상체질의학회지
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• 제19권3호
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• pp.217-226
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• 2007

1. Objectives The purpose of this study was to evaluate whether use of Yeoldahanso-tang(熱多寒少湯) may injure the liver function. We clinically studied the change of liver function rest in patients who were admitted in Dongseo Oriental Medical Hospital. 2. Methods We analyzed rhe serum alkaline phosphatase(AIP), aspartate aminotransferase(AST), alanine aminotransferase(ALT), ${\gamma}$-glutamyl transpeptidase(${\gamma}$-GT), total bilirubin of 25 patients from 1st. July. 2004 to 15th. October. 2007 admitted in Dongseo Oriental Medical Hospital. Liver function test were done on admission and before discharge. 3. Results For most patients, the values of AIP, AST, ALT, ${\gamma}$-GT and total bilirubin were within normal range or decreased. 4. Conclusions This study suggests that Yeoldahanso-tang(熱多寒少湯) does not injure liver function of human.

• Advances in Energy Research
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• 제4권1호
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• pp.29-45
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• 2016

There has been a growing interest in the recent time for the development of solar power tower plants, which are mainly used for utility scale power generation. Combined heat and power (CHP) is an efficient and clean approach to generate electric power and useful thermal energy from a single heat source. The waste heat from the topping Brayton cycle is utilized in the bottoming HRSG cycle for driving steam turbine and also to produce process steam so that efficiency of the cycle is increased. A thermal storage system is likely to add greater reliability to such plants, providing power even during non-peak sunshine hours. This paper presents a conceptual configuration of a solar power tower combined heat and power plant with a topping air Brayton cycle. A simple downstream Rankine cycle with a heat recovery steam generator (HRSG) and a process heater have been considered for integration with the solar Brayton cycle. The conventional GT combustion chamber is replaced with a solar receiver. The combined cycle has been analyzed using energy as well as exergy methods for a range of pressure ratio across the GT block. From the thermodynamic analysis, it is found that such an integrated system would give a maximum total power (2.37 MW) at a much lower pressure ratio (5) with an overall efficiency exceeding 27%. The solar receiver and heliostats are the main components responsible for exergy destruction. However, exergetic performance of the components is found to improve at higher pressure ratio of the GT block.

• Journal of the Optical Society of Korea
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• 제20권1호
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• pp.42-54
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• 2016

A hybrid color and grayscale images encryption scheme based on the quaternion Hartley transform (QHT), the two-dimensional (2D) logistic map, the double random phase encoding (DRPE) in gyrator transform (GT) domain and the three-step phase-shifting interferometry (PSI) is presented. First, we propose a new color image processing tool termed as the quaternion Hartley transform, and we develop an efficient method to calculate the QHT of a quaternion matrix. In the presented encryption scheme, the original color and grayscale images are represented by quaternion algebra and processed holistically in a vector manner using QHT. To enhance the security level, a 2D logistic map-based scrambling technique is designed to permute the complex amplitude, which is formed by the components of the QHT-transformed original images. Subsequently, the scrambled data is encoded by the GT-based DRPE system. For the convenience of storage and transmission, the resulting encrypted signal is recorded as the real-valued interferograms using three-step PSI. The parameters of the scrambling method, the GT orders and the two random phase masks form the keys for decryption of the secret images. Simulation results demonstrate that the proposed scheme has high security level and certain robustness against data loss, noise disturbance and some attacks such as chosen plaintext attack.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.1346-1351
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• 2004

This study is concerned with the thermal analysis during the cool-down period of 135,000 $m^3$ class GT-96 membrane type LNG carrier under IMO design condition. The cool-down is performed to cool the insulation wall and the natural gas in cargo tank for six hours to avoid the thermal shock at the start of loading of $-163^{\circ}C$ LNG. During the cool-down period, the spraying rate for the NG cooling decreases as the temperature of NG falls clown from $-40^{\circ}C$ to $-130^{\circ}C$ and the spraying rate for the insulation wall cooling increases as the temperature gradient of the insulation wall is large. It was confirmed that there existed the largest temperature decrease at the 1 st barrier and 1st insulation, which are among the insulation wall, especially in the top side of the insulation wall. By the 3-D numerical calculation about the cargo tank and the cofferdam during the cool-down period, the temperature variation in hulls and insulations is precisely predicted.

• Journal of Microbiology and Biotechnology
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• 제29권10호
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• pp.1553-1560
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• 2019

In a previous study, the antimicrobial peptides extracted from Lactobacillus plantarum UTNGt2 of wild-type fruits of Theobroma grandiflorum (Amazon) were characterized. This study aimed to investigate the antimicrobial mechanisms of peptides in vitro and its protective effect on fresh tomatoes. The addition of partially purified Gt2 peptides to the E. coli suspension cells at the exponential ($OD_{605}=0.7$) growth phase resulted in a decrease with 1.67 (log10) order of magnitude compared to the control without peptide. A marginal event (< 1 log10 difference) was recorded against Salmonella, while no effect was observed when combined with EDTA, suggesting that the presence of a chelating agent interfered with the antimicrobial activity. The Gt2 peptides disrupted the membrane of E. coli, causing the release of ${\beta}$-galactosidase and leakage of DNA/RNA molecules followed by cell death, revealing a bacteriolytic mode of action. The tomatoes fruits coated with Gt2 peptides showed growth inhibition of the artificially inoculated Salmonella cocktail, demonstrating their preservative potential.