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개심술후 폐기능 -수술직후 및 장기간의 추이에 대하여- (Pulmonary Function Following Open Heart Surgery -early and late postoperative changes-)

  • 이성행
    • Journal of Chest Surgery
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    • 제13권4호
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    • pp.364-374
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    • 1980
  • Twenty-two patients were selected for evaluation of pre-and postoperative pulmonary function. These patients were performed open cardiac surgery with the extracorporeal circulation from March 1979 to July 1980 at the Department of Thoracic and Cardiovascular Surgery, Kyungbook National University Hospital. Patients were classified with ventricular septal defect 5 cases, atrial septal defect 5 cases, tetralogy of Fallot 5 cases, mitral stenosis 4 cases, rupture of aneurysm of sinus Valsalva 1 case, left atrial myxoma I case, and aortic insufficiency 1 case. The pulmonary function tests were performed and listed: [1] respiratory rate, tidal volume [TV], and minute volume[MV], [2] forced vital capacity [FVC] and forced expiratory volume[FEV 0.5 & FEV 1.0], [3] forced expiratory flow [FEF 200-1200 ml & FEF 25-75%]. [4] Maximal voluntary ventilation [MVV], [5] residual volume [RV] and functional residual capacity[FRC], measured by a helium dilution technique. Respiratory rate increased during the early postoperative days and tidal volume decreased significantly. These values returned to the preoperative levels after postoperative 5-6 days. Minute volume decreased slightly, but essentially unchanged. Preoperative mean values of the forced vital capacity, functional residual capacity and total lung capacity decreased [63.2%, 87.2% & 77.3% predicted, respectively], and early postoperatively these values decreased further [19.6%, 76.0% & 38.0% predicted], but later progressively increased to the preoperative levels. In residual volume, there was no decline in the preoperative mean values [100.9% predicted] and postoperatively the value rather increased [106.3-161.7% predicted]. Forced expiratory volume [FEV 0.5 & FEV 1.0] and forced expiratory flow [FEF 200-1200 ml & FEF 25-75%] also revealed significant declines in the early postoperative period. There was no significant difference in values of the spirometric pulmonary function tests, such as FEF 1.O and FEF 25-75% between successful weaning group [17 cases] extubated within 24 hrs post-operatively and unsuccessful weaning group [5 cases] extubated beyond 24 hrs. Static compliance and airway resistance measured for the two cases during assisted ventilation, however, any information was not obtained. Long term follow-up pulmonary function studies were carried out for 8 cases in 9 months post-operatively. All of the results returned to the pre-operative or to normal predicted levels except FVC, FEV 1.0, and FEF 25-75% those showed minimal declines compared to the pre-operative figures.

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폐절제술 후 폐환기능의 변화에 대한 장기 추적관찰 (A Long-term Follow up Study on Pulmonary Function after Lobectomy and Pneumonectomy)

  • 이이형;김세규;장준;정경영;안철민;김성규;이원영
    • Tuberculosis and Respiratory Diseases
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    • 제40권6호
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    • pp.638-645
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    • 1993
  • 연구목적 : 폐절제술 후 폐환기능은 절제될 폐와 절제술 후 잔여 폐의 기능, 또한 잔여 폐의 잠재적인 대상능력에 의존한다. 최근에는 폐암 환자에서 광범위한 폐절제술이 행하여지는 추세이며 종종 만성폐질환으로 인하여 폐환기능이 상당히 손상된 환자에서도 이러한 수술이 행해지고 있는데 이들에서 절제술 후 폐기능의 회복정도를 예측함은 매우 중요하다. 본 연구의 목적은 폐절제술 후 폐기능의 변화를 장기간 관찰하여 기간에 따른 폐기능의 변화양상을 파악하여 폐절제술이 폐기능에 미치는 영향을 분석함에 있다. 방법 : 폐암 및 양성폐질환으로 전폐절제술 및 폐엽절제술을 시행받은 환자중 수술 후 특기할 만한 합병증이 없고, 18개월 이상 정기적으로 추적관찰이 가능하였던 16예를 대상으로 수술 전과 수술 후 5년동안 3개월 간격으로 폐환기능검사를 실시하여 폐기능의 변화양상을 분석하였다. 결과: 1) 수술 1주 후 폐기능은 폐엽절제군과 전폐절제군 각 군에서 수술전 측정치의 FVC 59.8%, 52.2%, FEV1 63.1%, 50.5%로서 예측치에 비하여 유의하게 낮았으며(p<0.05), 두군 사이에 유의한 차이는 없었고, 1-3개월 후 예측치와 유사하게 회복되었다. 2) FVC는 폐엽절제군은 6-24개월에는 예측치보다 높았고, 그 이후에는 예측치와 유사하게 유지되었으며, 전폐절제군에서는 6-36개월에는 예측치와 유사하게 유지되다가 수술 3년 6개월 이후에는 호전되어 예측치보다 약간 높게 유지되었다. 3) FEV1은 폐엽절제군과 전폐절제군 각각 6개월-5년동안 뚜렷한 변화없이 예측치와 유사하게 유지되었다. 4) FEV1/FVC는 두군 모두에서 수술 전후 전기간동안 통계학적으로 유의한 변화가 없었다. 5) FEF25-75%는 폐엽절제군에서는 6개월-5년동안 유의한 변화없이 예측치보다 높게 유지되었고, 전폐절제군에서는 수술 1년 이후 감소하여 예측치보다 낮게 유지되었다. 6) MVV는 폐엽절제군의 경우 2년까지는 예측치와 유사하게 유지되다가 그 후 약간 감소하는 경향을 나타내었고, 전폐절제군의 경우는 전 추적기간 동안 예측치와 유사하게 유지되었다. 7) 전폐절제군이 폐엽절제군에 벼해 수술 후 6개월의 FVC, FEV1, FEF 25-75%, MVV가 통계학적으로 유의하게 낮았으며(p<0.05), 수술 2년 이후에는 전폐절제군이 폐엽절제군보다 FVC, FEV1, FEF 25-75%가 낮은 경향을 보였으나 통계학적으로 유의하지는 않았다. 결론 : 폐환기능은 수술 직후에는 수술 전보다 현저히 감소하였다가 수술 1-3개월 후 회복되어 예측치와 유사해지고 6개월에 최고에 이르고, 2년 이후 약간 감소하여 5년까지 뚜렷한 변화없이 예측치와 유사하게 유지되었다. 폐엽절제군과 전폐절제군 사이의 폐환기능의 차이가 가장 뚜렷한 시기는 수술 6개월-1년 사이였고, 수술 2년 이후에는 두군 사이의 차이가 감소하였다.

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기관지 과민성이 동반된 중증 만성 폐쇄성 폐질환 환자에 대한 Salmeterol/Fluticasone Propionate와 Tiotropium Bromide 병합 요법과 단독 요법 치료효과 비교 (Comparison for the Effects of Triple Therapy with Salmeterol/Fluticasone Propionate and Tiotropium Bromide versus Individual Components in Patients of Severe COPD Combined with Bronchial Hyperresponsiveness)

  • 손지연;김소리;박성주;이흥범;이용철;이양근
    • Tuberculosis and Respiratory Diseases
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    • 제67권6호
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    • pp.536-544
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    • 2009
  • Background: A combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) is commonly prescribed for COPD patients but there is little data on their effectiveness, particularly in COPD patients with bronchial hyperresponsiveness. This study compared the spirometric improvement based on the change in $FEV_1$, $FEV_1$/FVC, and IC as well as the clinical outcomes of the therapeutic strategies with SFC and TIO versus the individual components in patients with severe COPD and bronchial hyperresponsiveness. Methods: This study examined the spirometric data and clinical outcomes of 214 patients with COPD and hyperresponsiveness, who were divided into three groups according to the therapeutic regimen (TIO only, SFC only, and a triple therapy regimen). Results: All regimen groups showed early improvement in the $FEV_1$ and IC (at 3- and 6 months after treatment). However, long-term beneficial effects were observed only in the SFC group (at 24 months after treatment). However, these beneficial effects decreased after a 36-month follow up. In all spirometric results, the 12-, 24-, and 36-months data showed a similar degree of improvement in the three groups. The triple therapy group showed higher St. George's Respiratory Questionnaire scores and lower acute exacerbations and hospitalization. Conclusion: SFC can be a more important component in the pharmacological treatment of severe COPD patients with hyperresponsiveness than TIO, particularly in the spirometric and clinical outcomes.

심호흡 방법에 따른 상복부 수술환자의 폐 환기능에 미치는 효과 (The Effect of Deep Breathing Methods on Pulmonary Ventilatory Function of Patients Who experiened Upper-abdominal surgery)

  • 황진희;박형숙
    • 기본간호학회지
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    • 제1권2호
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    • pp.129-147
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    • 1994
  • 본 연구는 수술환자의 술 후 폐환기능 회복을 돕기 위한 효과적인 간호중재의 자료를 제공하고자 부산시내에 소재한 P 대학병원의 일반욋과에 입원하여 전신마취하에 상복부 수술을 받은 환자 46명을 대상으로 하였으며, 자료수집기간은 1993년 11월 1일부터 12월 31일까지로 하였고, 처음 4주간동안 대조군을, 다음 4주간에 실험군을 자료수집하였다. 실험군에는 Incentive Spirometer를 사용한 심호흡법을, 대조군에는 호흡기구를 사용하지 않은 자발적인 심호흡법을 수술 후 의식이 회복된 직 후부터 매 1시간마다 규칙적으로 24시간동안 실시하였다. 폐환기능의 측정도구는 운반이 용이하고 사용이 간편하여 임상적으로 많이 이용되는 Vitalograph Compact를 사용하였으며, 수술 전과 수술 후 24시간, 수술 후48시간, 수술 후72시간, 각 각 4회에 걸쳐 대상자들의 노력성 폐활량과 일초 노력성 호기량을 측정하였다. 여기서 수집한 자료를 SPSS $PC^+$를 이용하여, 백분율, 평균, t검정, $X^2$검정, 일원변량분석으로 통계처리하였다. 본 연구의 결과를 요약하면 다음과 같았다. 1) 대상자들의 일반적특성은 여성이 41.3%, 남성이 58.7%이며, 평균연령은 $48.48{\pm}12.26$, 흡연습관은 대상자 전체의 43.5%가 있는 것으로 나타났으며, 과거 호흡기 질환은 전체의 8.7%가 앓은 경험이 있는 것으로 나타났다. 2) Incentive Spirometer를 사용한 심호흡방법은 수술 후의 노력성 폐활량에서 24시간에 $1.46{\pm}0.54L$, 48시간에 $1.58{\pm}0.60L$, 72시간에 $1.90{\pm}0.61L$로서 유의한 차이를 보였다(F=3.530, P=0.035). 즉 시간경과에 따라 폐환기능의 회복에 효과적이었다. 3) 호흡기구를 사용하지 않은 자발적인 심호흡 방법은 수술 후 노력성 폐활량이 24시간에 $1.19{pm}0.43L$, 48시간에 $1.35{\pm}0.42L$, 72시간에 $1.51{\pm}0.38L$로 유의한 차이를 보였고(F=3.480, P=0.037), 술 후 일초 노력성 호기량도 24시간에 $1.00{\pm}0.28L$, 48시간에 $1.20{\pm}0.37L$, 72시간에 $1.33{\pm}0.33L$로 유의한 차이를 보였으므로(F=6.153, P=0.004), 술 후 폐환기능 회복에 효과가 있다. 4) 실험군과 대조군의 수술 후 노력성 폐활량은 수술 후 72시간에서 실험군이 $1.90{\pm}0.61L$, 대조군이 $1.51{\pm}0.38L$로 유의한 차이를 보였다(t=2.620, P=0.013). 5) 실험군과 대조군의 수술 후 일초 노력성 호기량은 수술 후 24시간에서 $1.33{\pm}0.56L,\;1.00{\ge}0.28L$로 유의한 차이를 보였고(t=2.530, P=0.017), 술 후 72시간에서 $1.72{\pm}0.65L,\;1.33{\pm}0.3L$로 유의한 차이를 보였다(t=2.540, P=0.016). 6) 대상자의 술 후 폐환기능에 영향을 미치는 요인은 성별로 나타났다. 이에 따른 폐환기능의 차이를 보면, 실험군의 술 후 노력성 폐활량이 48시간에 남자($1.78{\pm}0.61L$)가 여자($1.27{\pm}0.45L$)보다 더 높게 나타났으며 (t=2.170, P=0.042), 72시간에도 역시 남자($2.16{\pm}0.56L$)가 여자($1.50{\pm}0.47L$)보다 더 높았다(t=2.910, P=0.008). 술 후 일초 노력성 호기량은 24시간에서 남자가 $1.54{\pm}0.60L$, 여자가 $1.00{\pm}0.30L$으로 유의하였고 (t=2.460, P=0.023), 48시간에 남자가 $1.64{\pm}0.62L$, 여자가 $1.09{\pm}0.41L$로 유의한 차이를 보였고(t=2.360, P=0.028), 72시간에도 남자($1.96{\pm}0.62L$)가 여자($1.33{\pm}0.50L$)보다 더 높게 나타났다(t=2.540, P=0.019). 즉 실험군의 술 후 폐환기능은 남자가 여자보다 더 우세하다는 것을 알 수 있었다. 이상의 요약된 연구결과를 토대로, 연구자는 다음과 같은 결론을 얻었다. Incentive Spirometer를 사용한 심호흡법이 호흡기구를 사용하지않은 자발적인 심호흡보다 술 후 폐환기능 회복에 있어서 더 우수한 방법이었다. 그러므로, 임상간호사는 상복부 수술환자의 술 후 폐환기능 회복을 돕고 나아가 폐합병증을 예방하기 위해 Incentive Spirometer를 사용한 규칙적인 심호흡법을 술 후에 간호중재의 한 방안으로 실시할 것을 권장하며, 아울러 병동의 사정 상 호흡기구의 비치가 가능하지 않다면 호흡기구를 사용하지않은 자발적인 심호흡법을 술후에 꾸준히 적용하는것도 임상간호학발정에 기여하리라고 본다.

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호흡근 강화훈련이 뇌졸중환자의 폐 기능에 미치는 영향 (Effects of Respiratory Muscle Strengthening Training on Pulmonary Function in Persons with Stroke : A Preliminary Study)

  • 이성란;이정민;이정은;이해정
    • 대한물리치료과학회지
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    • 제19권4호
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    • pp.47-52
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    • 2012
  • Purpose : The purpose of the study was to examine if a respiratory muscle strengthening training in patients with stroke can improve their pulmonary function. Methods : Volunteers were included for the study if a patient diagnosed stroke more than 6 months and had 24 points or higher in MMSE-K scores. Twenty-eight subjects participated in this study and were randomly divided into two groups; a breathing exercise group(n=14) and a control group(n=14). The intervention for all subjects was conducted for 20minutes, three times a week for 4 weeks. Subjects for the breathing exercise group had the respiratory muscle strengthening training using spiro-tigers, where-as subjects in the control group got their usual treatment ie a postural training. The six-minute walking test(6MWT) and the pulmonary function tests(FVC, $FEV_1$, $FEV_1$/FVC, VC, Vt, IRV and ERV) were employed to assess treatment effects at baseline and after their intervention. Results : Twenty-four subjects finished their 4-week treatment programs. The general characteristics between groups were found to be similar (p>0.05). The pulmonary function between groups were also observed no difference across groups at the baseline measurement (p>0.05). In the post treatment group comparison, subjects in the breathing exercise group showed an increase in lung function with VC ($2.73{\pm}0.80{\ell}$) and Vt ($0.87{\pm}0.38{\ell}$) than those in the control group ($1.91{\pm}0.80{\ell}$ and $0.48{\pm}0.22{\ell}$ respectively) (p<0.05). However, there was no difference found in 6MWT, FVC, $FEV_1$, $FEV_1$/FVC, IRV, and ERV across groups (p>0.05). Conclusion : A significant increase in VC and Vt was found in subjects with stroke, who had four-week training on respiratory muscle strengthening. However, respiratory muscle strengthening showed no effect on walking speed and FVC, $FEV_1$, $FEV_1$/FVC, IRV, and ERV in patients with stroke.

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진동 자극 유무에 따른 호흡 저항 훈련 시 폐 기능과 호흡근의 즉각적인 차이가 있을까? (Is There Any Immediate Difference between Pulmonary Function and Respiratory Muscle, with or without Vibration Stimulation in Respiratory Resistance Training?)

  • 박진영;김예슬;박현주;이명모
    • 대한물리치료과학회지
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    • 제25권3호
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    • pp.17-24
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    • 2018
  • Purpose: The purpose of this study was to investigate the effect of whole body vibration combined breathing resistance on lung capacity and respiratory muscle and to suggest a mediation method for improvement of respiratory function and lung function in the future. Methods: This study was a preliminary study design of two groups of 54 healthy young adults who were randomly assigned to an experimental group (n=27) with core exercise combined with respiratory resistance and whole body vibration and a control group with respiratory resistance and core exercise (n=27). All interventions consisted of 6 core exercises every 40 seconds and rest for 20 seconds. To compare the effects of intervention, we measured spirometry and respiratory muscle strength. Results: Both the experimental group and the control group showed a significant increase in Forced vital capacity (FVC) and Maximum voluntary ventilation (MVV) (p<.05). However, FEV1 and FEV1% were significantly increase only in the experimental group (p<.05). FVC, FEV1%, Maximum Inspiratory Pressure (MIP), Maximum Expiratory Pressure (MEP) showed more significant increase in the experimental group than the control group. Conclusion: These findings indicate that whole-body vibration combined breathing resistance is an effective intervention for people, with FVC, FEV1%, MIP, MEP increase.

제한성 환기장애의 진단에서 폐활량검사의 정확성 (Accuracy of Spirometry at Predicting Restrictive Pulmonary Impairment)

  • 안영미;고원중;김철홍;임성용;안창혁;서지영;정만표;김호중;권오정
    • Tuberculosis and Respiratory Diseases
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    • 제54권3호
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    • pp.330-337
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    • 2003
  • 연구배경 : 폐활량검사에서 노력성 폐활량(forced vital capacity, FVC)이 감소되었을 때 제한성 환기장애가 있다고 일반적으로 판단한다. 하지만 제한성 환기장애 판정의 정확한 기준은 총폐용량(total lung capacity, TLC)의 감소이다. 본 연구는 폐활량검사 결과에서 FVC가 감소되었을 때 TLC가 감소된 제한성 환기장애를 얼마나 정확히 예측할 수 있는가를 알아보고자 하였다. 대상 및 방법 : 1999년 1월부터 2000년 12월까지 2년간 폐기능검사실에서 폐활량검사와 폐용적검사를 동일한 날 시행한 성인 환자 1,371명의 폐기능검사 결과를 후향적으로 조사하였다. FVC, $FEV_1$, TLC는 측정값이 정상 예측값의 80% 미만일 때 감소하였다고 판정하였고, 1초간 노력호기폐활량의 노력성 폐활량에 대한 비($FEV_1$/FVC%)는 측정값이 70% 미만일 때 감소하였다고 판정하였다. 결 과 : 1,371례 중 FVC가 감소한 환자는 353례였으며 이 중 TLC가 감소된 경우는 186례로 양성예측률은 52.7%이었다. FVC가 정상인 1,018례 중 TLC가 감소한 경우는 45례로 음성예측률은 96.6%이었다. 폐활량검사에서 제한성 환기장애($FEV_1$/FVC 정상, FVC 감소)를 보인 196례 중 TLC가 감소된 경우는 148례로 양성예측률은 75.5%이었다. 폐활량검사에서 혼합성 환기장애($FEV_1$/FVC 감소, FVC 감소)를 보인 157례 중 TLC가 감소된 경우는 38례로 양성예측률은 24.2%이었다. 혼합성 환기장애를 보인 196례 중 FVC와 $FEV_1$의 예측값에 대한 비율이 15% 미만의 차이를 보인 60례에서 TLC의 감소를 보인 경우는 34례(56.7%)였다. 결 론 : 제한성 환기장애를 배제하는 데는 폐활량검사가 유용하다. 하지만 폐활량검사에서 FVC가 감소된 환자에서 제한성 환기장애의 유무는 TLC의 측정을 통해 확인하는 것이 필요하리라 사료된다.

한국인 중년성인에서 사상체질과 폐기능장애, 대사증후군의 연관성 연구 (Association between Sasang Constitution, Impaired Lung Function and Metabolic Syndrome among Middle-aged Adults in Korea)

  • 박윤성;김제신;이준희;이의주;고병희
    • 사상체질의학회지
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    • 제25권3호
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    • pp.180-194
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    • 2013
  • Objectives Impaired lung function(ILF) and sasang constitution(SC) is associated with metabolic syndrome(MS). However, the relationship between ILF and SC is unclear. So, we assessed the relationship between ILF and MS according to SC, and examined whether SC is an independent risk factor for ILF. Methods This study included 1,148 subjects 40years and older who were performed the health examination at Kyung Hee University Hospital in Korea between December 2011 and February 2013. We defined ILF if FVC or $FEV_1$ value were less than lower limit of normal(LLN), and classified ventilatory patterns as obstructive pattern and restrictive pattern. MS was assessed according to AHA/NHLBI criteria. We used multivariate logistic regression to analyze the association of ILF with MS respective to SC types, and to identify the risk of SC types for ILF. Odds ratio(OR) was calculated by adjusting for age, sex, smoking status, drinking, physical activity, and BMI. Results In whole subjects, ILF was associated with MS [OR (95% CI), 1.69 (1.24-2.31) for FVC, 1.67 (1.20-2.33) for $FEV_1$]. And in Taeeum type(TE type) and Soeum type(SE type), ILF was associated with MS [1.63 (1.10-2.42) for FVC, 1.48 (1.01-2.24) for $FEV_1$ in TE type; 6.93 (1.14-42.00) for FVC in SE type], while in Soyang type(SY type), it wasn't. The restrictive pattern was associated with MS in TE type and SE type, while in SY type, it wasn't. Furthermore, TE type and SY type had more risk for ILF than SE type [1.71 (1.12-2.59) for SY type, 1.95 (1.23-3.08) for TE type in FVC; 2.06 (1.26-3.36) for TE type in $FEV_1$; 1.85 (1.21-2.85) for SY type, 2.17 (1.35-3.49) for TE type in Restrictive pattern]. Conclusions These results show that SC is an independent risk factor for ILF, especially TE type and SY type than SE type, and the prevalence of MS is an independent risk factor for ILF in TE type.

미만성 폐질환에 대한 개흉적 폐생검 (Open Lung Biopsy for Diffuse Infiltrative Lung Disease)

  • 김남혁
    • Journal of Chest Surgery
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    • 제28권11호
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    • pp.1014-1018
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    • 1995
  • To confirm diagnosis and to set proper therapeutic strategy, open lung biopsies were done in 57 patients who were suspected for diffuse interstitial lung disease from January 1985 to December 1994. Among them, 35 were male and 22 were female[M:F=l.6: 1 and mean age of the patients is 53.5$\pm$ 2.3[24-81 years. Tissue for histologic studies were obtained from left lung in 33, from right lung in 24according to the distributions of the pathology. Preoperative diagnostic work-up`s were chest X-ray, CT[HRCT scan, sputum study, bronchoscopy[BAL, TBLB and PTNA and all of them were unsuccessful to confirm diagnosis. In comparison of pulmonary function tests between preoperative and postoperative values, there were no significant differences in FVC, FEV1, FEV1/FVC[p 0.05 but in AaDO2[p[0.05 . Postoperative complications including atelectasis, wound infection, pulmonary edema and respiratory insnfficiency, were shown in 5 cases[8.8% , and two of them were died of respiratory failure and sepsis[mortality rate 3.5% . Pathologic diagnosis was confirmed in 53 cases postoperatively but it was undetermined in 4[diagnostic yield rate 93.0% . In comparison between preoperative clinical diagnosis and postoperative pathologic diagnosis, new diagnosis were made in 17 cases[29.8% and preoperative tentative diagnosis were confirmed histologically in 36 cases[63.2% . In 4 cases[7.0% , however, diagnoses were not confirmed after biopsies. Therapeutic plans were reset in 46 cases[80.7% in accordance with the final diagnosis.In conclusion, open lung biopsy is recommended for a specific diagnosis and proper therapeutic plan in diffuse interstitial lung diseases because of its high diagnostic yield Irate and it`s relatively low morbidity and mortality rate in these tompromised patents.

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Pulmonary Function and Its Influence Factors of Residents in Yeosu Industrial Complex

  • Hong, Eun-Ju;Ahn, Gi-Sub;Chung, Eun-Kyung;Guo, Xinbiao;Son, Bu-Soon
    • 한국환경과학회지
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    • 제20권7호
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    • pp.799-809
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    • 2011
  • Objectives: This study is aimed at identifying the influential factors on the pulmonary function of ordinary residents in the surrounding areas of Yeosu Industrial Complex. Methods: The PFT (Pulmonary Function Test) was conducted on the target residents numbering 989 people (male 361, female 628). The exposed group (813 people) resided within the radius of 5km from Yeosu Industrial Complex and the control group (176 people) resided in the radius of more than 15 km from May 2007 to November 2007. The survey also took into account other factors including personal characteristics, life habits, respiratory diseases and allergic symptoms, medical histories, and the living environments of the residents in order to further identify influential factors on pulmonary function. Result: When comparing the PFT values of the exposure groups to the control group of the same city, values of the exposure groups were meaningfully lower with an %$FEV_1$ of 107.05% and %FVC of 100.28%. Conversely, the control group reported an %$FEV_1$ and %FVC of 107.26% and 102.85% respectively, indicating that ambient air pollutants reduce lung function. The odds ratio of asthma diagnosis history increased when a subjects residence was close to a heavily trafficked road, traffic amount was huge, a bed was used, and the family had less than four members. However the results were not statistically meaningful. The odds ratios of abnormal pulmonary function were statistically higher among those with asthma(OR=4.29, CI=1.75-10.56), wheezing (OR=2.59, CI=1.24-5.41), and nasal congestion (OR=2.87, CI=1.36-6.08) (p<0.01). The factors affecting $FEV_1$ were symptoms including asthma, passive smoking and allergic eye disease ($R^2$=0.049, p<0.001). For the FVC symptoms including asthma ($R^2$=0.014, p<0.001) were measured. The analysis showed that FVC decreased with increases in $O_3$ and CO(p<0.01). Furthermore, $FEV_1$ decreased with increases in $O_3$(p<0.01). Conclusions: These results will provide preliminary data for establishing responsive measures to protect the health of residents in industrial complexes from air pollution, and to develop lasting environmental health policies.