• 한국정밀공학회지
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• 제17권3호
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• pp.39-46
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• 2000

In this paper, the analysis of dynamic characteristics and performance investigation of the ER damper are investigated. The ER damper is based on a double rod actuator and an electric field are applied to the moving electrode composed of cylinder and piston. The performance of the ER damper is length of piston electrode field and its velocities. The experimental and calculated results show that the characteristic of the ER damper varies with the magnitude of the electric field.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2002년도 추계학술대회논문초록집
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• pp.348.1-348
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• 2002

This paper deals with the vibration reduction of the hull mount system of ship structures brought by ER smart structures. The hull mount is used to isolate the vibration form the immersed structures. Utilizing the tunable characteristics of ER fluids, ER insert are made In the hull mountint structure. Different types of ER inserts are proposed and the vibration characteristics are investigated. (omitted)

• 미생물학회지
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• 제43권1호
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• pp.54-58
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• 2007

청국장은 미생물, 효소, 다양한 생리활성물질을 포함하는 대두발효식품으로 정장, 핼액순환개선 효과 등이 알려져 있다. 청국장에 존재하는 isoflavone이 유방암, 전립선암의 억제와 관련이 있을 수 있다. 본 연구에서는 HPLC와 Mass 분석을 통해 분말청국장 100% ethanol추출물에 aglycone 형태의genistein, daidzein, glyciten이 존재함을 확인했다. 당이 붙어 있는 genistin, daidzin, OH기가 추가적으로 붙어 있는 8-OH-genistein, 8-OH-daidzein은 존재하지 않았다. Estrogen 수용체에는 $ER{\alpha},ER{\beta}$가 있다. $ER{\alpha}$는 유방암, 전립선암의 촉진에, $ER{\beta}$는 이들 암의 억제와 관련이 있을 것으로 추정한다. 인간의 estrogen 수용체가 cloning되어 있는 효모의 전사촉진 assay를 이용하여, 청국장에 있는 isoflavone이 $ER{\beta}_{1}$를 선택적으로 자극할 수 있음을 확인했다.

• 한국공작기계학회논문집
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• 제16권2호
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• pp.100-105
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• 2007

Electro-rheological(ER) fluid and valve are fabricated and evaluated experimentally in its durability to utilize the hydraulic control systems for long term operation. The two-ports ER valve used in the experiment consist of twelve parallel multi-layer electrodes and provide a restriction to the passage of ER fluid because of the viscous pressure drop and a component induced by the electric field. The durability test of ER valve are performed by measuring the surface roughness of electrodes with variation of an electric field strength and test time(1000 or 1800min.). Also, the shear stress and shear rate are measured to evaluate the durability of ER fluid as function of time. After durability test, ER shear stress increases approximately proportional to the shear rate with applied electric field intensity, In the ER valve, the center line average height roughness(Ra) of copper electrode increases about 1.56 times and ten-point median height roughness(Rz) increases about 2.2 times after the durability test. An understanding of these durability is essential to predicting the service life of ER fluid and valves.

• Tribology and Lubricants
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• 제14권3호
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• pp.7-16
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• 1998

The electrorheological (ER) behavior of suspensions in silicone oil of phosphoric ester cellulose powder (average particle size: 17.77 $\mu$m) was investigated at room temperature with electric fields up to 2.5 KV/mm. For development of anhydrous ER suspensions using at wide temperature range, we aimed to know the effect of activation of phosphoric ester cellulose particles on the ER activities. As a first step, the anhydrous ER suspensions mixing with the phosphoric ester cellulose particles which were treated with 2M phosporic acid and 4M urea were measured. After activating the anhydrous ER suspensions at 12$0^{\circ}C$, not only the analysis of dispersing cellulose particles which were reacted by phosphoric ester but also the electrorheological characteristics of ER suspensions such as dielectric constant, current density, electrical conductivity and rheological properties were studied. From the experimental results, the activation of phosphoric ester cellulose particles had an influence on the ER properties of anhydrous ER suspensions. As the activation time went by, the size and number of dispersing particles, the electrical properties and the initial apparent viscosity $(η_0)$ of ER suspensions were increased till the activation time passed 5 hours. Also, it was possible, the electrorheological effect $($\tau$/$\tau$_0)$ of ER fluids was grown by the activation of phosphoric ester cellulose particles.

• 한국기계가공학회지
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• 제4권1호
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• pp.49-55
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• 2005

This paper presents experiments on the evaluation of characteristics of ER fluids used for vibration control of application in intelligence type process control systems. Dynamic characteristics of the actuator(beam) embedded with the ER fluid can be controlled by changing the strength of the electric field applied on the ER fluids, thus provides a mean to avoid the resonance. In case electric field is supplied to the smart structure with ER fluids, vibration energy is dissipated more than the beam without electric field, because particles in ER fluid form a chain structure in the presence of electric field. The damping and stiffness of the beam with ER fluid are increased when the applied electric field increases. The characteristics of damping and stiffness of the ER fluid with various electric field strength were investigated by conducting a vibration test of the beam with ER fluid. If it applies characteristics of the ER fluids, it will be able to apply in the PLC control system for the vibration which occurs from process system.

• 전력전자학회논문지
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• 제7권5호
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• pp.453-464
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• 2002

ER 유체(Electrorheological fluid)는 인가 전계에 따라 유체의 점도(Viscosity)와 댐핑력(Damping force)이 변화하는 혼합물질이며 반능동 현가장치, 고속 클러치, 진동 흡수장치 등에 적용되고 있다. ER 유체의 응용을 위해서는 강한 전계를 인가해 줄 수 있는 고전압 가변 전원장치가 필요하다. 본 논문에서는 반능동 현가장치에 적용하기 위한 전원장치의 개발에 대하여 기술하였다. ER 유체의 전기적 특성, 고전압 전원장치의 요구조건, 전원장치의 설계 및 제작에 대하여 설명하였으며 최종적으로 실험을 통하여 개발된 고전압 전원장치가 ER 유체 응용에 적합함을 검증하였다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2008년도 Proceedings of the Convention
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• pp.55-74
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• 2008

Previously, we have shown that hypoxia, through HIF-1, induces ligand-independent $ER{\alpha}$ activation and the physical interaction of HIF-1 and $ER{\alpha}$. However, the effect of hypoxia on the transactivation of $ER{\beta}$ is not yet known. In the present study, we found that hypoxia activated the $ER{\beta}$-mediated transcriptional response in the HEK 293 cell line, as determined by the transient expression of$ER{\beta}$ and ER-responsive reporter plasmids. The hypoxia-induced estrogen response element-mediated transcriptional response was dependent on $ER{\beta}$ expression and was inhibited by the ER antagonist ICI 182,780. Transactivation of $ER{\beta}$ was induced by the expression of HIF-$1{\alpha}$ under normoxic conditions, as determined by the expression of oxygen-independent stable GFP-HIF-$1{\alpha}$. HIF-$1{\alpha}$-induced $ER{\beta}$ transactivation was abolished by the inhibition of HIF-$1{\alpha}$ activation. This was determined by using chemical inhibitors for the MAPK pathway. In addition, HIF-$1{\alpha}$ interacted with $ER{\beta}$ in a mammalian-two hybrid assay. We conclude that hypoxia activates $ER{\beta}$ in a ligand-independent manner, possibly through the interaction of HIF-$1{\alpha}$ and $ER{\beta}$.

• Journal of Mechanical Science and Technology
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• 제19권8호
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• pp.1621-1631
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• 2005

In this paper, making the best use of the features of the electro-rheological (ER) valve, a two-port pressure control valve using ER fluids is proposed and manufactured. The ER-Valve characteristics are evaluated by changing the intensity of the electric field and the number of electrode. As only with electrical signal change to the ER-Valve in which ER fluid flowing, ER fluid flow is controlled, so development of simple ER-Valves have been tried. The ER-Valves and pressure drop check method are considered to be applied to the fluid power industry. Using the manufactured pressure control valve, a one-link manipulator with FHA (Flexible Hydraulic Actuator) is driven. As a result, it is experimentally confirmed that the pressure control valve using ER fluids is applicable to use in driving actuator. If it applies characteristics of the ER fluids, it will be able to apply in the control system for the ER Valve which occurs from industrial controller. After having durability test, shear stress increased regularly because of starch particles crushed by pump and particle size that was almost the same. Moreover, Ra of copper electrode increased about 1.56 times rather than before those of performing durability test, and Rz increased about 2.2 times.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1111-1113
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• 2012

The ER-/PR+ breast tumor may be the result of a false ER negative result. The aim of this study was to investigate whether there is a difference in patient and tumor characteristics of the ER-/PR+ phenotype in an Asian setting. A total of 2629 breast cancer patients were categorized on the basis of their age, ethnicity, tumor hormonal receptor phenotype, grade and histological type. There were 1230 (46.8%) ER+/PR+, 306 (11.6%) ER+/PR-, 122 (4.6%) ER-/PR+ and 972 (37%) ER-/PR-. ER-/PR+ tumors were 2.5 times more likely to be younger than 50 years at diagnosis (OR: 2.52; 95% CI: 1.72-3.67). Compared to ER+/PR+ tumors, the ER-/PR+ phenotype was twice more likely to be associated with grade 3 tumors (OR:2.02; 95%CI: 1.00-4.10). In contrast, compared to ER-/PR- tumors, the ER-/PR+ phenotype was 90% less likely to be associated with a grade 3 tumor (OR: 0.12; 95%CI:0.05-0.26), and more likely to have invasive lobular than invasive ductal histology (OR: 3.66; 95%CI: 1.47-9.11). These results show that the ER-/PR+ phenotype occurs in a younger age group and is associated with intermediate histopathological characteristics compared to ER+/PR+ and ER-/PR- tumors. This may imply that it is a distinct entity and not a technical artifact.