• Title/Summary/Keyword: $D_{50}$

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Vitamin D Level in Blood of Menopausal Women over 50 and the Relation with the Proportion Requiring Dental Scaling (50세 이상 폐경여성의 혈중 비타민 D 농도와 치면세마필요자율의 관련성)

  • Lee, Sun Hee;Roh, Sang Chul
    • Journal of dental hygiene science
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    • v.13 no.4
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    • pp.393-402
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    • 2013
  • The purpose of this study was to examine the relationship between vitamin D and periodontal diseases based on the raw data of the 5th National Health & Nutrition Examination Survey of 2010. The subjects in this study were 1,327 people, and those whose data on major variables were missing and who suffered from diabetes and/or osteoporosis were excluded. As for data analysis, R2.15.1 program and PASW Statistics 18.0 were utilized. The findings of the study were as follows: 1. As for all the respondents aged 50 and up, there was no significant relationship between vitamin D and periodontal diseases. 2. As for the post-menopausal women including the women who underwent bilateral ovariectomy, the vitamin D-deficit group 1 (<10) were 6.66-fold more likely to suffer from periodontal diseases than the vitamin D-sufficient group (${\geq}30$) (OR, 6.66; 95% CI, 1.004~44.19). The above-mentioned findings ascertained that vitamin D had a significant negative correlation to periodontal diseases among the post-menopausal women including the women who underwent bilateral ovariectomy. This finding should be taken into account in terms of the prevention and management of periodontal diseases.

Effect of Vitamin D Supplementation on the Physiological Indices, Muscle Mass, and Physical Functions of Aged Women (비타민 D 섭취가 여성노인의 생리적 지표, 근육량 및 체기능에 미치는 영향)

  • Kim, In Kyung;Kim, Ok Soo
    • Korean Journal of Adult Nursing
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    • v.25 no.5
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    • pp.539-548
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    • 2013
  • Purpose: The purpose of this study was to investigate the effect of supplemental vitamin D on the physiological indices, muscle mass, and physical functions of aged women. Methods: A non-equivalent pretest-posttest design was used. The participants were 65 elderly women with low serum vitamin D levels. This study was conducted for 12 weeks. The experimental group (n=34) received vitamin D and regular exercise whereas the control group (n=31) received only regular exercise. The data were analyzed by the IBM PASW Statistics (SPSS) 19.0 program. Results: Serum vitamin D (U=0.00, p<.001), parathyroid hormone (U=99.50, p<.001) and calcium (U=250.50, p<.001) levels were significantly increased in the experimental group after the intervention. The experimental group showed significantly increased scores of muscle mass, strength, physical balance, and gait compared to those of the control group. Conclusion: Vitamin D supplementation improved physiological indices, muscle mass, and physical functions. In addition, this program may help to prevent disorders of the musculoskeletal system in aged women.

IEEE 1500 Wrapper Design Technique for Pre/Post Bond Testing of TSV based 3D IC (TSV 기반 3D IC Pre/Post Bond 테스트를 위한 IEEE 1500 래퍼 설계기술)

  • Oh, Jungsub;Jung, Jihun;Park, Sungju
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.1
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    • pp.131-136
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    • 2013
  • TSV based 3D ICs have been widely developed with new problems at die and IC levels. It is imperative to test at post-bond as well as pre-bond to achieve high reliability and yield. This paper introduces a new testable design technique which not only test microscopic defects at TSV input/output contact at a die but also test interconnect defects at a stacked IC. IEEE 1500 wrapper cells are augmented and through at-speed tests for pre-bond die and post-bond IC, known-good-die and defect free 3D IC can be massively manufactured+.

Phenolic Compounds from Barks of Actinidia arguta Planchon Growing in Korea and its Anti-Oxidative and Nitric Oxide Production Inhibitory Activities (국내산 다래나무 수피의 페놀성 화합물의 항산화 및 Nitric Oxide 생성 억제 활성)

  • Lim, Hyun-Woo;Shim, Jae-Geul;Choi, Hyung-Kyoon;Lee, Min-Won
    • Korean Journal of Pharmacognosy
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    • v.36 no.3 s.142
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    • pp.245-251
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    • 2005
  • Phytochemical examination of the barks of Actinidia arguta led to the isolation of five flavonoids. Structures of compounds were elucidated as catechin (1), (-)-epicatechin (2), quercetin (3), $quercetin-3-O-{\beta}-D-glucopyranoside$ (4), $quercetin-3-O-{\beta}-D-galactopyranoside$ (5) by comparison with previously reported spectral evidences. To investigate the anti-oxidative effect and nitric oxide (NO) production inhibitory activity of these compounds, DPPH radical scavenging activity and nitric oxide production inhibitory activity in $IFN-{\gamma}$, LPS stimulated RAW 264.7 cell were examined. The $IC_{50}s$ were determinied as follows : $1\;$IC_{50}=26.61\;{\mu}g/ml$, $2\;IC_{50}=25.30\;{\mu}g/ml$, $3\;IC_{50}=20.41\;{\mu}g/ml$, $4\;IC_{50}=18.23\;{\mu}g/ml$ , $5\;IC_{50}=30.46\;{\mu}g/ml$, $6\;IC_{50}=28.0;{\mu}g/ml$, $7\;IC_{50}=27.24\;{\mu}/ml$. These NO production inhibitory effects were significantly different compared with the positive control, L-NMMA $(IC_{50}=20.77\;{\mu}g/ml)$, respectively. Compound $1\;(IC_{50}=6.19\;{\mu}g/ml)$, $2\;(IC_{50}=8.98\;{\mu}g/ml)$, $3\;(IC_{50}=7.30\;{\mu}g/ml)$ and $4\;(IC_{50}=7.64\;{\mu}g/ml)$ also showed potent antioxidative activities similar level to ascorbic acid $(IC_{50}=9.22\;{\mu}g/ml)$. These results suggest that barks of A. arguta have a potent anti-oxidative and anti-inflammatory activity.

Assessment of Visual satisfaction & Visual Function with Prescription Swimming goggles In-air and Underwater (도수 수경 착용시 실내와 수중에서의 시각적 만족도 및 시력 평가)

  • Chu, Byoung-Sun
    • Journal of Korean Ophthalmic Optics Society
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    • v.18 no.4
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    • pp.357-363
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    • 2013
  • Purpose: To investigate the visual function with prescription swimming goggles. Methods: 15 university students (mean age: $22{\pm}1.54$ years) participated, with a mean distance refractive error of RE: S-1.67 D/C-0.40 D, LE: S-1.70D/C-0.37 D. Inclusion criteria were no ocular pathology, able to wear soft contact lenses to correct their refractive error to emmetropia and able to swim. Participants were fitted with contact lenses to correct all ametropia. Subjective evaluation for satisfaction of visual acuity, asthenopia and balance were also measured using a questionnaire while wearing swimming goggles with cylinder (C+1.50 D, Ax $90^{\circ}$) compared with plano sphere outside the swimming pool area. Visual acuity was assessed using the same ETDRS chart. The prescription swimming goggles powers were assessed in random order and ranged in power from S+3.00 D to S-3.00 D in 0.50 D steps. Results: Subjective evaluation was significantly worse for the swimming goggles with cylinder than for the plano powered goggles for all 3 questions, visual acuity, asthenopia and balance. Visual acuity were significantly affected by the different power of the swimming goggles (p<0.05), but there was no significant difference between the in-air in-clinic and underwater in-swimming pool measures (p=0.173). However, visual acuity measured in the clinic was significantly better than underwater for some swimming goggle powers (+3.00, +1.00, +0.50, 0, -1.00 and -2.00 D). Conclusions: Wearing swimming goggles underwater may degrade the visual acuity compared to within air but as the difference is less than 1 line of Snellen acuity, and it is unlikely to result in significant real-life effects. Having an incorrect cylinder correction was found to be detrimental resulting in lower score of satisfaction. Considering slippery floor of swimming pool area, it can be a potential risk factor. Therefore, it is important to correct any refractive error in addition to astigmatism for swimming goggle.

Inhibitors of Tyrosinase and Melanogenesis from Galla rhois

  • Kim, Hyo-Jin;Jang, Dong-Il;Park, Sang-Won
    • Preventive Nutrition and Food Science
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    • v.2 no.4
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    • pp.285-290
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    • 1997
  • Previously, a 50% aqueous methanol extract of Galla rhois was shown to be the most potent tyrosinase inhibition activity with an {TEX}$IC_{50}${/TEX}(the concentration causing 50% inhibition of tyrosinase activity) of 0.2mg/ml of 205 crude drug extracts. To isolate tyrosinase inhibitors, the methanol extract was evaporated to a small volume in vacuo, and then partitioned stepwise with benzene and ethyl acetate(EtOAc). the EtOAc fraction was solubilized in 10% MeOH solution, and then fractionated successively by Diaion HP-20 and Sephadex LH-20 column chromatography, and preparative HPLC. Three phenolic compounds were isolated, and characterized as gallic acid(GA), methyl gallate(MG) and 1,2,3,4,6-penta-O-galloyl-$\beta$-D-glucose(PGG) by UV, IR, {TEX}${1}^H${/TEX}-&{TEX}${13}^C${/TEX}-NMR, and FAB-MS spectroscopy, PGG({TEX}$IC_{50}${/TEX}=50$\mu\textrm{g}$/ml) showed a considerable inhibitory effect against mushroom tyrosinase, while GA({TEX}$IC_{50}${/TEX}=1.6mg/ml) and MG({TEX}$IC_{50}${/TEX}=234$\mu\textrm{g}$/ml) did not show an appreciable effect. Meanwhile, MG inhibited greatly melanogenesis in a murine melanocyte cell line, Mel-Ab. MG and PGG showed typical noncompetitive inhibition patterns against mushroom tyrosinase. These results suggest that PGG and MG may be potentially useful as either anti-browning or anti-melanogenic agents in foods and cosmetics.

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Growth and Nutrient Utilization in Kids Fed Expander-extruded Complete Feed Pellets Containing Red Gram (Cajanus cajan) Straw

  • Reddy, P. Baswa;Reddy, T.J.;Reddy, Y.R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.12
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    • pp.1721-1725
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    • 2012
  • A growth and digestibility study was conducted using Osmanabadi goat male kids by feeding complete diets in the form of mash or expander extruded pellets containing different levels of red gram (Cajanus cajan) straw (RGS). Two iso-nitrogenous complete diets were prepared by incorporating RGS at 35% and 50% levels. Half the quantity of each complete mash feed was then converted into pellets through expander extruder processing. Thirty two kids of 4 to 5 months age were divided into four groups of eight each and were fed for 150 d with four experimental diets (T1: mash with 35% RGS, T2: mash with 50% RGS, T3: pellets with 35% RGS and T4: pellets with 50% RGS). Pelleting of complete diets significantly (p<0.001) increased the voluntary feed intake (671.45 vs 426.28 g/d) at both levels of RGS in the feeds. Average daily gain (ADG, g/d) also increased significantly (p<0.001) from 48.79 in kids fed mash diet to 71.29 in those fed with pelleted diets. Feed conversion efficiency (dry matter (DM) intake: weight gain) was comparable among all the treatment groups. Digestibility of nutrients was not affected by pelleting of the feeds whereas, increasing the level of inclusion of RGS in feeds from 35% to 50% decreased (p<0.05) the digestibility of DM and crude protein (CP) resulting in lower (p<0.001) metabolizable energy (ME) content (MJ/kg DM) in feeds with 50% RGS (7.93 vs 8.75). Daily intake (MJ/kg $BW^{-0.75}$) of ME decreased (p<0.05) in feeds containing 50% RGS while pelleting of feeds increased (p<0.05) the intake of DM, CP, digestible crude protein (DCP) and ME. It is inferred that expander extruder pelleting can efficiently utilize RGS up to 50% level in complete diets for growing goat kids.

Study on the Establishment of Shelf-life of Domestic Exporting Pork (수출용 돼지고기의 유통기한 설정에 관한 연구)

  • 김영환;김일석;신대근
    • Food Science and Preservation
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    • v.6 no.2
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    • pp.188-193
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    • 1999
  • This study was carried out to examine the quality of Korean pork regular loins and hams which m exported in Japanese market. The samples were stored at 0${\pm}$1$^{\circ}C$(A, B companies) and 2${\pm}$1$^{\circ}C$(C, D companies). In analysis of Korean pork exported to Japanese market, the pork of A and D companies showed below 10$\^$6/CFU/$\textrm{cm}^2$ of total aerobic bacteria at 40 days storage and panels felt off-flavor after 40 days. Therefore the edible period will be 40 days through the analysis of microbe and sensory test in porks of A and D companies. The porks of B and C companies showed over 10$\^$6/CFU/$\textrm{cm}^2$ of total aerobic bacteria at 50 days storage and panels couldn't feel off-flavor in sensory test after 50 days. Therefore the edible period will be 50 days through the analysis of microbe and sensory test in porks of B and C companies. As the results, shelf-life of A and D companies will be 32 days and B and C companies will be 40 days from edible period by a factor of 0.8. In analysis of stored pork for export in Korean market, the porks of A and B companies showed over 10$\^$6/CFU/$\textrm{cm}^2$ at 40 days storage and C and D companies did over 10$\^$6/CFU/$\textrm{cm}^2$ at 30 days storage in analysis of microbe. The pork of A and D companies showed 10$^4$CFU/$\textrm{cm}^2$ but B and C companies did 10$\^$5/CFU/$\textrm{cm}^2$ at 50 days in coliform count. Therefore shelf-life of the pork of A company was logest and the next were B and C, but shelf-life of the pork of D company was 20 days, therefore it was even shorter than the others.

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Changes in binaural beat strength to the difference of right and left hearing ability (좌우 청력 차이에 따른 바이노럴 비트 세기의 변화)

  • Kim, Seong Chan;Choi, Min Joo
    • The Journal of the Acoustical Society of Korea
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    • v.39 no.1
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    • pp.57-63
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    • 2020
  • The binaural beat is a subjective beating phenomenon due to the frequency difference of sounds heard in both ears, sensed by the human brain. The beating magnitude physically depends on the amplitudes of the two signals with slight different frequencies. Therefore, the binaural beat strength is expected to be affected by the difference in left and right hearing ability. In this study, 34 healthy subjects without hearing loss were chosen. They hear a pure tone sound (450 Hz) at 10 different Sound Pressure Levels (SPLs) (from 50 dB to 27.4 dB) through the one side of ears, while they hear the reference sound (440 Hz, 50 dB) through the other side of ears. Their subjective assessment using a semantic differential method reveals that the binaural beat strength decreases as SPL differences between the two sides of ears increases, if the difference is greater than 2.2 dB. The result suggests that the hearing loss difference between the two sides of ears should be less than 2.2 dB to maximize binaural beating effects.

Optimizing and Modeling Brightness Development in Peroxide Bleaching of Thermomechanical Pulp

  • Yoon, Byung-Ho;Wang, Li-Jun;Park, Soo-Kyoung;Kim, Dong-Yoon
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 1999.11a
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    • pp.180-186
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    • 1999
  • Alkaline peroxide bleaching of (chemi) mechanical pulp is a very complicated system where various process factors affect the bleaching performance and pulp properties. Traditional on-factor-at a time method is ineffective and costly in finding the optimal bleaching conditions. In this study statistical experimental methods which include three steps. I. e. screening, response surface modeling and optimization, were used to find the conditions for maximal brightness development during one stage alkaline peroxide bleaching of TMP which had an initial brightness of 54.5% Elerpho. The TMP was pretreated with EDTA(0.5% on O. D. pulp. consistency, $30^{\circ}C$ for 60 minutes) and bleached in a 2L Mark V Quantum Reactor at 750rpm, 7.5% of bleaching consistency and with 0.05% magnesium sulfate addition. The ranges of other factors studied were 1~5% hydrogen peroxide on O. D plup, 1~4% sodium hydroxide on O. D pulp and 1~4% sodium silicate on O. D pulp, reaction temperature 50~$90^{\circ}C$ and reaction time 40~180minutes. A models with good predictability was established and the maximal brightness after one stage bleaching was found to be 70% Elerpho at $50^{\circ}C$, 50 minutes 5% hydrogen peroxide on O. D. pulp 3.2~3.4% sodium hydroxide on O. D. pulp 3.2~3.4% sodium hydroxide on O. D pulp and 4% silicate on O. D pulp. However further studies on other pulp properties such as strength and brightness stability shall be carried out in order to find out the optimal bleaching conditions.

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