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Associations of Cognitive Function and Dietary Factors in Elderly Patients with Alzheimer's Disease (알쯔하이머병 노인들의 인지기능과 관련된 식이 요인)

  • Jung, Kyong-Ah;Lee, Yo-A;Kim, Seong-Yoon;Jang, Nam-Soo
    • Journal of Nutrition and Health
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    • v.41 no.8
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    • pp.718-732
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    • 2008
  • The purpose of this study was to investigate nutrients or food factors related to cognitive function of elderly having Alzheimer's disease. In this study 38 subjects who were over 65 years old have participated in dementia clinic at A medical center. After they were diagnosed to Alzheimer's Disease (AD) through blood analysis, neuropsychological test, brain image and interview by medical specialist, we examined for their general information, anthropometry, blood pressure and dietary intakes. Dietary intakes were investigated using the 24-hour recall record. Energy intake was adequate and the energy composition of carbohydrate, protein and fat was 60.8 : 16.2 : 23.0, but dietary intakes of calcium, vitamin A and folate were less than 75% of the recommended intake levels for Koreans. The multiple regression analysis adjusted with age, sex and educational level showed that cognitive function was positively related to intakes of zinc, fishes and shellfishes, beans & nuts, sugars and fats, and negatively related to intakes of plant calcium and eggs. These results indicate that intakes of specific nutrients or food groups are associated with the specific domains of cognitive function in elderly with AD.

Synthesis of Polyamine Type Flocculant and Properties in Potable Water Treatment (Polyamine계 고분자 응집제의 합성 및 상수 처리 특성)

  • Park, Lee-Soon;Shin, June-Ho;Choi, Sang-June;Shin, Myung-Chul;Lee, Seok-Hun
    • Applied Chemistry for Engineering
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    • v.9 no.4
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    • pp.542-547
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    • 1998
  • Polyamine type polymer flocculants were synthesized and their characterization, viscosity and flocculation studies were conducted. In order to increase the molecular weight of polyamine flocculant which was prepared by polycondensation reaction from dimethylamine and epichlorohydrin, a small amount of 1,6-hexanediamine was employed. The incorporation of 1,6-hexanediamine up to 5.5 mole % replacing corresponding part of dimethylamine gave a branched type polyamine sample with increased intrinsic viscosity ([${\eta}$]=0.46 in 1 wt % aqueous NaCl solution). The amount of 1,6-hexanediamine above 5.5 mole %, however, resulted in gelation during polymerization. Utilizing raw water from Maegok potable water treatment plant, it was found that the addition of polyamine flocculant at a concentration of 1 mg/L level could reduce the amount of polyaluminum chloride (PAC) inorganic flocculant by half (15 mg/L). It was also observed that the incoporation of polyamine flocculant at 1 mg/L level was effective in the higher pH raw water, while PAC inorganic flocculating agent alone was not effective.

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The Trend of Food and Nutrient Intakes of Korean(1969~1989) -The Third Report, Nutrient Intake from the Annual Report of the National Nutrition Survey- (한국인의 식품 및 영양섭취상태 추이(1969~1989) -제3보, 국민영양조사보고서에 의한 영양섭취상태를 중심으로-)

  • Park, Mi-A;Kim, Eul-Sang;Lee, Kyu-Han;Moon, Hyun-Kyung;Song, In-Jung;Tchai, Bum-Suk
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.6
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    • pp.655-661
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    • 1992
  • Form reports of the Korean National Nutrition Survey from 1969 to 1989, trends of nutrients intakes are reported as follows. The amount of energy intakes are decreased gradually. The proportion of energy from cereals to total energy are decreased from 85.9 percent at 1969 to 66.5 percent at 1989. There are increasing trend for the proportion of energy from animal foods to the total energy. The amount of protein intakes are increasing gradually. The ratio of animal protein to the plant protein have been increasing since the survey has been started. The amount of fat intakes are also increasing. The proportion of energy from the fat and protein to total energy had been shown increasing trends. Gradually, the calcium and iron intakes are increasing over the years. But the intakes of calcium is less than the average dietary allowance of subject examine until recently. The intakes of thiamin, showing adequate intake, are almost equal to the average dietary allowance. For the riboflavin, the amount of intakes are increasing from the mid nineteen-eighty. But the intake of riboflavin is less than the average dietary allowance. For the niacin and ascorbic acid, the amount of intakes are showing variations. But the amount of intakes are not inadequate.

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Survey on the Chitinolytic Activity from Some Plants for the Industrial Utilization (공업적 이용을 위한 식물성 키틴분해효소의 탐색)

  • Han, Beom-Ku;Lee, Woo-Jin;You, Tak;Park, In-Ho;Jo, Do-Hyun
    • Applied Biological Chemistry
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    • v.39 no.6
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    • pp.466-471
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    • 1996
  • The survey on the chitinolytic activity of some plants was performed for the purpose of obtaining some reliable and inexpensive sources of chitinase. Rice, soybean for sprouting, kiwi fruit, almond and crude papain were investigated. Rice bran, seed coat of the soybean and the pericarp of kiwi fruit showed a considerable activity, while the bean after the removal of the seed coat, the mixture of rice integument and endosperm, polished rice, and defatted soybean powder didn't have any detectable activity. These crude enzymes have shown to contain both endo- and exochitinase activity. The effects of pH and temperature on the enzyme activity were variable. Furthermore we have observed the chitosanolytic activity from these enzyme Preparations. The rice bran had the highest activity in the enzymatic degradation of chitosan, and seed coat of soybean and the pericarp of kiwi fruit followed. On the basis of the fact that crude papain was not only commercially available but also the most potent in the endochitinase activity and the lowest in the exochitinase activity, we could conclude that crude papain was considered as the most suitable source of the chitinase among plants studied in this paper. In addition, rice bran was worth further investigation from the point of utilizing agricultural by-product.

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The effect of artemisinin on the rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice (개똥쑥에서 분리(分離)된 artemisinin이 가토(家兎) IgG에 의해 유발(誘發)된 생쥐의 현독성(賢毒性) 혈청사구체현염(血淸絲球體賢炎)에 미치는 영향(影響))

  • Zhu, Quan
    • Journal of Haehwa Medicine
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    • v.4 no.2
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    • pp.335-336
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    • 1996
  • Artemisinin, a new antimalarial to treat patients infected with strains of Plasmodium jalciparum, derived from the plant Artemisia annua Linn, has immunopharmacologic actions such as enhence the PHA -induced lymphocyte transformation rate, increased the weight of spleen but reduced the weight of thymus, reduced phagocytic function of peritoneal macrophage, remarkably reduced the level of serum IgG and hemolysin fonning capacity (sentitized with SRBC), inhibited the activity of Ts cells of donor mice by supraoptimal immunuization(SOI), but enhenced activity of Ts cells of recipient mice by SOI. These results suggested that Ts cells may be the target cells of artemisinin. To the serum complement C3 level of plasmodium berghei-infeted mice, artemisinin (i. m,) could remarkly increase it. The artemisinin also obviously reduced the prostaglandin E(PGE) in the mouse hind paw swelling induced by carrageenin. Numerous studies have demonstrated that pharmacologic doses of PGE attenuate the development of immunocomplex nephritis. Some autologous immune mechanisms may be invoolved In the pathogensis of some types of glomurulonephritis. Glomerular abnormalities can be induced in animals by variety of immunological manipulations. The resulting disorder has many clinical and pathogical similarities to the disease in human. Our purpose was therefore to test the ability of the artemisinin to lessen the severity of rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice model. Mice which had treated with rabbit IgG and NTS, administrated with saline, showed Significant inceases of urinary protein, cholesterol level, and decrease of serum albumin in NS group. On the contrary, By i.g. adminstration of artemisinin at dose of 12.5, 25 and 50 mg/kg for 14 days after NTS injection, shown that artemisinin inhibited the nephritic changes in some parameters by means of urinary protein(p<0.05, p<0.01) and serum choleterol(p<0.05, p<0.01) and albumin (p<0.05, p<0.01), blood urea nitrogen (p<0.05, p<0.01), serum albumin(p<0.05, p<0.01); Cyclophosphamide(i.p. 10mg/kg for 14d) had almost same effect as the artemisinin had. Morphological studies shown that The picture of kidney from the mouse with NTS-nephritis accerated with rabbit IgG, treated with i.g. saline as the control, the mesangiocapillary were enlarged and proliferated; There were inflammatory cells infiltrating around the glomeruli; The ethelial cell were proliferated in the wall of Bowman's capsule. Histopatholological picture of kidney from the NTS-nephritis accerated with rabbit IgG mouse treated with i.p. 10mg/kg cyclophosphamide as the positive control. No siginicant histopathological evidence were found. Treaded with i.p. 12.5mg/kg artemisinine, the picture shown that mesangiocapillary were lightly proliferated; There were inflammatory cells infiltrating around the glomeruli; Treaded with i.p. 25mg/kg artemisinine, The picture shown that the mesangiocapillary were lightly proliferated; Treaded with i.p. 50mg/kg artemisinine, The picture shown that both the mesangiocapillary proliferated and the inflammatory cells infiltrating around the glomeruli are less than treated with saline, 12.5 and 25 mg/kg artemisinine. On the basis of these studies we conclude that the artemisinin can relieve pathological change caused by NTS-nephritis aacerated with rabbit IgG.

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Catalpol Content and Antioxidant Activities in Various Cultivars of Rehmannia glutinosa (품종별 지황의 Catalpol 함량 및 항산화능)

  • You, Bo-Ram;Kim, Hye-Ran;Kim, Hyo-Jin;Lee, Ji-Yeon;Lee, Sang-Yong;Song, Mi-Ran;Park, Jong -Yoon;Kim, Mee-Ree
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.4
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    • pp.481-485
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    • 2011
  • This study was to investigate catalpol content and antioxidant activities in five cultivars (Kokang, Suwon 10, Suwon 11, Jiwhang 1 and Korea) of Rehmannia Radix. Catalpol content was analysed by HPLC using $C_{18}$ column ($150{\times}4.6\;mm$, $5{\mu}m$), 1% acetonitrile and a UV detector. The standard curve was found to be a linear regression of y=0.0483x-0.0841 ($R^2$=0.999). The catalpol content ranged from 85.2 mg/g to 144.9 mg/g, of which the Korea was the highest among cultivars. The total phenol content in Rehmannia Radix was 0.358~0.459 mg/g, of which the Korea was the highest among cultivars. The antioxidant activities determined by DPPH and hydroxyl radical scavenging activities were the highest in Korea with $IC_{50}$ of 205.8 mg/g for DPPH radical scavenging activity and $IC_{50}$ of 38.8 mg/g for hydroxyl radical scavenging activity. Based on these results, the Korea among Rehmannia Radix cultivars was suggested to be a potent medicinal plant material for antioxidant activities.

A Study on the Filed application of Environmental Friendly Porous Concrete For Retaining Wall (환경친화 옹벽용 포러스콘크리트의 현장적용성에 관한 연구Ⅱ)

  • Kim, Jeong-Hwan;Lee, Nam-Ik;Lee, Jun;Park, Seung-Bum;Jang, Young-Il;Seo, Dae-Suck
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.04a
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    • pp.817-820
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    • 2008
  • The river environments of many streams in korea have been deteriorate through the rapid industrialization and urbanization since the 1960s. In korea, on the other hand, much efforts on the research and project have been made for the restoration of the deteriorated streams to close-to-nature. in order to restore the deteriorated streams, therefore, it is necessary to investigate such advanced technologies and materials. In view of this requirement, various research paths are being taken focusing on coarse aggregates to make multi-functional porous concrete having continuous voids so as to improve water and air permeability, acoustic absorption, water purification and applicability to vegetation. The Purpose of this study is to investigate the method for recovery of the environment in the streams area using porous concrete retaining wall block. the multi-P.O.C block applies for test in the Jangduri-cheon have been monitored planting, stability etc. after 6 months, plant grows flourishing and reconstructed in state such as nature rivers.

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Antioxidant Activity and Radioprotection of Two Flavonoids from Propolis (프로폴리스에서 분리한 플라보노이드 화합물의 항산화 활성 및 방사선 방어효과)

  • Jeong, Ill-Yun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.2
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    • pp.162-166
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    • 2005
  • Two flavonoids, 7-O-methyl-3',4'-didehydroxy quercetin (MDQ) and quercetin, isolated from Chinese propolis, which is the generic name for the resinous substance collected by honeybees from various plant sources, were tested for their antioxidant activity and protective effect against radiation-induced DNA damage in mouse lymphocytes. In antioxidant test, both compounds provided a dose-dependent scavenging effect on DPPH radical and a dose-dependent inhibitory effect on lipid peroxidation in mouse liver. Quercetin showed stronger scavenging and inhibitory effect than MDQ, and it also provided strong inhibition on superoxide anion radical generated in xanthine-xanthine oxidase system, but there was no inhibitory ability for MDQ. In comet assay using single cell gel electrophoresis, MDQ and quercetin showed a protective effect against DNA damage caused by gamma irradiation. They reduced DNA damage to 54% (p<0.01) and 53% (p<0.01) at 25 $\mu$mol, respectively. These results suggest that free radical scavenging seems to be associated with their catechol form on the B ring, and radioprotection appears to be a likely mechanism of antioxidant activity by these flavonoids.

Phytosociological Community Classification of Mountain Ridge from Guryongryeong to Mt. Yaksu in the Baekdudaegan, Korea (백두대간의 구룡령에서 약수산 마루금의 식생구조 특성에 관한 연구)

  • An, Hyun-Chul;Choo, Gab-Chul;Park, Sam-Bong;Cho, Hyun-Seo;An, Jong-Bin;Park, Jeong-Geun;Ha, Hyoun Woo;Kim, Jin Joong;Kim, Bong-Gyu
    • Korean Journal of Environment and Ecology
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    • v.28 no.6
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    • pp.741-750
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    • 2014
  • To investigate the vegetation structure of mountain ridge from Guryongryeong to Mt. Yaksu, 22 plots ($100m^2$) installed with random sampling method were surveyed. Three groups of Quercus mongolica-Acer pseudosieboldianum community, Q. mongolica community, Cornus controversa-Q. mongolica community were classified by cluster analysis. Q. mongolica was a major woody plant species in the ridge area from Guryongryeong to Yaksusan and Carpinus cordata and C. controversa was partly occupied in some area. High positive correlations showed between Q. mongolica and Symplocos chinensis for. pilosa, Rhododendron schlippenbachii; Tilia amurensis and Tilia mandshurica, Symplocos chinensis for. pilosa; Tilia mandshurica and S. chinensis for. pilosa, R. schlippenbachii; Betula costata and Acer mono; Symplocos chinensis for. pilosa and Rhododendron schlippenbachii, and relatively high negative correlations showed between A. pseudosieboldianum and S. chinensis for. pilosa, R. schlippenbachii. Species diversity(H') of investigated groups were ranged 0.8170~1.1446 and it was lower compared to those of the ridge area of the national parks in Baekdudaegan.

A Study on the Correlation between Plant Community and Environmental Factors of Tongdosa(Temple) Area, Gajisan(Mt.) Provincial Park (가지산도립공원 통도사지구의 식물군락과 환경요인의 상관관계)

  • Lee, Sang-Cheol;Kang, Hyun-Mi;Kim, Ji-Suk;Yu, Chan-Yeol;Choi, Song-Hyun
    • Korean Journal of Environment and Ecology
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    • v.28 no.6
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    • pp.715-724
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    • 2014
  • Tongdosa, which is located in Gajisan(Mt.) Provincial Park of Yangsan City, is one of three representative temple in Korea. The purpose of this study was to investigate a relation between plants community and environmental factors in Tongdosa(Temple) District of Gajisan(Mt.) Provincial Park. In order to find out vegetation structure of Gajisan(Mt.) Provincial Park, thirty one plots(unit size: $200{\sim}300m^2$) were set up and surveyed. For environmental factors, it were surveyed and analyzed physical factors such as altitude, aspect etc. and soil characteristics such pH, organic content, total nitrogen content, exchangeable cation and so on. Using DCCA technique, a relation between plants community and environmental factors were analyzed. The surveyed plots were divided into five groups which are Pinus densiflora - Quercus aliena, Carpinus tschonoskii - Q. spp., P. densiflora - C. tschonoskii, P. densiflora - Q. variabilis, and Q. variabilis - Q. mongolica community. Vegetation succession was progressed from Pinus densiflora toward Carpinus tschonoskii and Quercus spp. It was found out that the distribution of vegetation was affected by altitude. Pinus densiflora - Quercus aliena community is located lower altitude and Q. variabilis - Q. mongolica community is located higher area.