• Title/Summary/Keyword: $C^*$-integral

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Impact of Treatment Type on Overall Survival in Elderly Brazilian Women with Breast Cancer

  • Bello, Marcelo Adeodato;de Menezes, Raquel Ferreira;de Sousa Silva, Brunna;da Silva, Rafael de Carvalho;Cavalcanti, Rousiane Silva;da Costa Moraes, Thayane de Fatima;Tonellotto, Fabiana;de Aguiar, Suzana Sales;Martucci, Renata Brum;Bergmann, Anke;Thuler, Luiz Claudio Santos
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4769-4774
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    • 2016
  • Objective: To analyze the survival of elderly patients with breast cancer according to the type of treatment used. Methods: A cohort study of women aged 80 or over with breast cancer registered with the Brazilian National Cancer Institute (Instituto Nacional do $C{\hat{a}}ncer$ - INCA) between 2008 and 2009 was conducted. Prognosis was analyzed according to the cancer treatment performed: surgery, radiotherapy, or hormone therapy. Analysis of the overall 5-year survival rate was performed using the Kaplan - Meier method, and comparisons of curves were undertaken using the log-rank test. For multiple regression analysis, Cox regression was used, adjusting for age and clinical stage, considering values of p < 0.05 as significant. Data were all analyzed using the statistical package SPSS version 20. Results: 70 women with a mean age of $84.0{\pm}3.7years$ at diagnosis participated in the study. The median follow-up time was 37.1 months (range 0.5-75.5), and 31 deaths (44.3%) occurred during this time. The median survival time was 51.2 months (95% CI, 44.9-57.4), higher in those who underwent surgery (p = 0.012) and those who had hormone therapy (p=0.001). Treatment with surgery reduced the risk of death by 61.7% (HR 0.3; 95% CI, 0.1-0.6; p = 0.001) when adjusted for clinical stage and age at diagnosis. However, there was no significant benefit from radiotherapy (HR 1.2; 95% CI, 0.5-2.5; p = 0.694). Conclusion: Treatment with surgery and hormone therapy increased the survival of our Brazilian patients with breast cancer aged 80 or over.

Numerical Simulation of Liquid Sloshing in Three- Dimensional Tanks (3차원(次元) 탱크내에서의 액체(液體) 슬로싱의 수치(數値) 해석(解析))

  • J.H. Hwang;I.S. Kim;Y.S. Seol;S.C. Lee;Y.K. Chon
    • Journal of the Society of Naval Architects of Korea
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    • v.28 no.1
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    • pp.12-18
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    • 1991
  • Three-dimensional nonlinear sloshing effects due to tank motions are simulated by solving boundary value problem using the panel method based on boundary integral technique. While Shinkai used boundary elements on which source strengths vary linearly between nodes, the source of constant strength is distributed on each triangular panel in the present study. The source strength at each time step is determined by solving the Fredholm integral equation of the second kind obtained from Green's theorem. To avoid cumulative numerical errors as time elapses, Adam-Bashforth-Moulton method is employed. Numerical examples for the case of partially filled spherical tank on board oscillating in harmonic sway mode or pitch mode are solved. The elevation of the free surface is compared with the result by Shinkai and confirmed in good agreement during early time. The input and the output energy are comparatively evaluated to check the overall accuracy of the present numerical scheme. Although some leakage of energy are found as time marches, it is plausible when we take into account nonlinearities of the problem and the number of panels of the model.

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A Study on the Vent Path Through the Pressurizer Manway and Steam Generator Manway under Loss of Residual Heat Removal System During Mid-loop Operation in PWR (가압경수로의 부분충수 운전중 잔열제거계통 기능 상실사고시 가압기와 증기발생기 Manway 유출유로를 이용한 사고완화에 관한 연구)

  • Y. J. Chung;Kim, W. S.;K. S. Ha;W. P. Chang;K. J. Yoo
    • Nuclear Engineering and Technology
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    • v.28 no.2
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    • pp.137-149
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    • 1996
  • The present study is to analyze an integral test, BETHSY test 6.9c, which represent loss of RURS accident under mid-loop operation. Both the pressurizer manway and the steam generator outlet plenum manway are opened as vent paths in order to prevent the system from pressurization by removing the steam generated in the core. The main purposes are to gain insights into the physical phenomena and identify sensitive parameters. Assessment of capability of CATHARE2 prediction can be established the effective recovery procedures using the code in an actual plant. Most of important physical phenomena in the experiment could be predicted by the CATHARE2 code. The peak pressure in the upper plenum is predicted higher than experimental value by 7 kPa since the differential pressure between the pressurizer and the surge line is overestimated. The timing of core uncovery is delayed by 500 seconds mainly due to discrepancy in the core void distribution. It is demonstrated that openings of the pressurizer manwey and the steam generator manway can prevent the core uncovery using only gravity feed injection. Although some disagreements are found in the detailed phenomena, the code prediction is considered reasonable for the overall system behaviors.

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A Study on the contamination measurement of spacecraft components under High Vacuum Environment (고진공하에서의 위성체 부품의 오염측정에 관한 연구)

  • 이상훈;서희준;문귀원;최석원
    • Journal of the Korean Vacuum Society
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    • v.11 no.2
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    • pp.87-96
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    • 2002
  • Outgassing from such sources as paints, coatings, adhesives and other non-metallic surfaces can contaminate satellites, especially second surface mirror and optical lens, it cause satellite to fail in own missions. The vacuum bake-out test using high temperature(more than $85 ^{\circ}C$)and high vacuum(less than $5.0{\times}1-^{-3}$ Pa) certify that the components of satellite work properly and can survive and operate in space environment like high vacuum. In the bake-out chamber installed at SITC of KARI, Rotary vacuum pump and Booster pump produce low vacuum of 5.0 Pa, and then two cryopumps produce high vacuum of below $5.0{\times}10^{-3}$ Pa. Also 48 ceramic heaters were provided to simulate high temperature. During the vacuum bake-out test, we detected contaminants using RGA(Residual Gas Analyzer) and measure the outgassing rate of the contaminant using the TQCM(Thermoelectric Quartz Crystal Microbalance). Also, IR/UV Spectrometer and witness plate be used to certify that the components were suitable for the spacecraft. This paper includes the preparation and procedures of the bake-out test for SAR(Solar Array Regulator) and MLI(Multi Layer Insulator), which were the components of the spacecraft. Especially, we discussed the methods and results of the contamination measurement. In the bake-out for SAR, the contamination was measured continuously although it was on the decrease from TQCM results. And RCA established that it is a highly polymerized compound. In the MLI bake-out using RGA and witness plate, we didn't detect any contamination materials.

A Study on Operating Method to Save Energy from the Adsorption Dryer in the Process of Purifying Compressed Air (고순도 압축공기 제조시스템의 흡착식 Dryer에서 에너지절감을 위한 운전방법에 관한 연구)

  • Kang, Seok-Wan;Chang, Sung-Ho;Kim, Hyeon-Joon;Kim, Sung-Soo;Lee, Yeong-Wook
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.3
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    • pp.180-191
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    • 2016
  • Optimizing energy usage for maximum efficiency is an essential goal for manufacturing plants in every industrial manufacturing sector. The generation and distribution of purifying compressed air is a large expense incurred in practically all manufacturing processes. Not only is the generation and treatment expensive equipment of compressed air, but frequent maintenance and effective operation is also required. As a plant's compressed air system is often an integral part of the production process, it needs to be reliable, efficient, and easy to be maintain. In this paper, we study to find operating method to save energy from the adsorption dryer in the process of purifying compressed air, which is required for a clean room production site in "A" company. The compressed air passes through a pressure vessel with two "towers" filled with a material such as activated alumina, silica gel, molecular sieve or other desiccant material. This desiccant material attracts the water from the compressed air via adsorption. As the water clings to the desiccant, the desiccant particle becomes saturated. Therefore, Adsorption dryer is an extremely significant facility which removes the moisture in the air $70^{\circ}C$ below the dew point temperature while using a lot of energy. Also, the energy consumption of the adsorption dryer can be varied by various operating conditions (time, pressure, temperature, etc). Therefore, based on existing operating experiments, we have searched operating condition to maximize energy saving by changing operating conditions of the facility. However, due to a short experiment period (from September to October), further research will be focused on considering seasonality.

Performance of carbon fiber added to anodes of conductive cement-graphite pastes used in electrochemical chloride extraction in concretes

  • Pellegrini-Cervantes, M.J.;Barrios-Durstewitz, C.P.;Nunez-Jaquez, R.E.;Baldenebro-Lopez, F.J.;Corral-Higuera, R.;Arredondo-Rea, S.P.;Rodriguez-Rodriguez, M.;Llanes-Cardenas, O.;Beltran-Chacon, R.
    • Carbon letters
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    • v.26
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    • pp.18-24
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    • 2018
  • Pollution of chloride ion-reinforced concrete can trigger active corrosion processes that reduce the useful life of structures. Multifunctional materials used as a counter-electrode by electrochemical techniques have been used to rehabilitate contaminated concrete. Cement-based pastes added to carbonaceous material, fibers or dust, have been used as an anode in the non-destructive Electrochemical Chloride Extraction (ECE) technique. We studied the performance of the addition of Carbon Fiber (CF) in a cement-graphite powder base paste used as an anode in ECE of concretes contaminated with chlorides from the preparation of the mixture. The experimental parameters were: 2.3% of free chlorides, 21 days of ECE application, a Carbon Fiber Volume Fraction (CFVF) of 0.1, 0.3, 0.6, 0.9%, a lithium borate alkaline electrolyte, a current density of $4.0A/m^2$ and a cement/graphite ratio of 1.0 for the paste. The efficiency of the ECE in the traditional technique using metal mesh as an anode was 77.6% and for CFVF of 0.9% it was 90.4%, with a tendency to increase to higher percentages of the CFVF in the conductive cement-graphite paste, keeping the pH stable and achieving a homogeneous ECE in the mass of the concrete contaminated with chlorides.

DIRECT PRODUCTED W*-PROBABILITY SPACES AND CORRESPONDING AMALGAMATED FREE STOCHASTIC INTEGRATION

  • Cho, Il-Woo
    • Bulletin of the Korean Mathematical Society
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    • v.44 no.1
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    • pp.131-150
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    • 2007
  • In this paper, we will define direct producted $W^*-porobability$ spaces over their diagonal subalgebras and observe the amalgamated free-ness on them. Also, we will consider the amalgamated free stochastic calculus on such free probabilistic structure. Let ($A_{j},\;{\varphi}_{j}$) be a tracial $W^*-porobability$ spaces, for j = 1,..., N. Then we can define the corresponding direct producted $W^*-porobability$ space (A, E) over its N-th diagonal subalgebra $D_{N}\;{\equiv}\;\mathbb{C}^{{\bigoplus}N}$, where $A={\bigoplus}^{N}_{j=1}\;A_{j}\;and\;E={\bigoplus}^{N}_{j=1}\;{\varphi}_{j}$. In Chapter 1, we show that $D_{N}-valued$ cumulants are direct sum of scalar-valued cumulants. This says that, roughly speaking, the $D_{N}-freeness$ is characterized by the direct sum of scalar-valued freeness. As application, the $D_{N}-semicircularityrity$ and the $D_{N}-valued$ infinitely divisibility are characterized by the direct sum of semicircularity and the direct sum of infinitely divisibility, respectively. In Chapter 2, we will define the $D_{N}-valued$ stochastic integral of $D_{N}-valued$ simple adapted biprocesses with respect to a fixed $D_{N}-valued$ infinitely divisible element which is a $D_{N}-free$ stochastic process. We can see that the free stochastic Ito's formula is naturally extended to the $D_{N}-valued$ case.

Elastic Behavior of Contact Lense(I) : Effect of Vibration (콘택트 렌즈의 탄성에 관한 연구(I) : 진동에 의한 영향)

  • Kim, Dase-Soo
    • Journal of Korean Ophthalmic Optics Society
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    • v.4 no.2
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    • pp.1-16
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    • 1999
  • Differential equations and its numerical solution program using Turbo-C were formulated to describe the radical distribution and average displacement amplitude of vibrating dehydrated contact lens(HEMA) driven by sinusoidal or rectangular pressure. The natural resonant frequency of the lens diaphram(thickness 0.08mm, diameter 14mm, curvature radius 8mm) was measured to be 5730 Hz from the extrapolation of frequency vs addedmass to the diaphram curve. The Young's modulus of the lens was measured to be $4{\times}10^9$ Pa with altering the original shape. The effect of parameters such as thickness, effective radius, damping coeff., amplitude of driving pressure on the vibration characteristics was illustrated by the computer simulation of the derived program. When the frequency of driving pressure coincides with the integral multiple of fundamental resonance frequency of the lens the wave pattern changes from arc to bell-shape along the radial position of the diaphram. If this happens to the contact lens on the cornea in vivo, it might create the feel of pull of the lens due to the increased rise of central part of the lens.

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Gust durations, gust factors and gust response factors in wind codes and standards

  • Holmes, John D.;Allsop, Andrew C.;Ginger, John D.
    • Wind and Structures
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    • v.19 no.3
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    • pp.339-352
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    • 2014
  • This paper discusses the appropriate duration for basic gust wind speeds in wind loading codes and standards, and in wind engineering generally. Although various proposed definitions are discussed, the 'moving average' gust duration has been widely accepted internationally. The commonly-specified gust duration of 3-seconds, however, is shown to have a significant effect on the high-frequency end of the spectrum of turbulence, and may not be ideally suited for wind engineering purposes. The effective gust durations measured by commonly-used anemometer types are discussed; these are typically considerably shorter than the 'standard' duration of 3 seconds. Using stationary random process theory, the paper gives expected peak factors, $g_u$, as a function of the non-dimensional parameter ($T/{\tau}$), where T is the sample, or reference, time, and ${\tau}$ is the gust duration, and a non-dimensional mean wind speed, $\bar{U}.T/L_u$, where $\bar{U}$ is a mean wind speed, and $L_u$ is the integral length scale of turbulence. The commonly-used Durst relationship, relating gusts of various durations, is shown to correspond to a particular value of turbulence intensity $I_u$, of 16.5%, and is therefore applicable to particular terrain and height situations, and hence should not be applied universally. The effective frontal areas associated with peak gusts of various durations are discussed; this indicates that a gust of 3 seconds has an equivalent frontal area equal to that of a tall building. Finally a generalized gust response factor format, accounting for fluctuating and resonant along-wind loading of structures, applicable to any code is presented.

학술정보 커뮤니케이션 시스팀으로서의 대학출판부

  • 이영자
    • Journal of Korean Library and Information Science Society
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    • v.8
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    • pp.155-184
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    • 1981
  • The publication of the result of scholarly research is an integral part of the process by which learning is advanced. The university presses, as one of the major scholarly publishers are now confronted with many critical problems, such as the declining unit sales, the explosion of manuscripts, the challenge of new publishing technologies, etc., in performing the role of the scholarly communication system. The purpose of this study is to identify the problems imposed on the university presses and alternative strategies for them. For the study, the related literature to the subject were read, analyzed and synthesized, from which the overall prospect of the problems and alternative strategies are derived. The conclusion of the study can be summarized as follows: (1) The faith of the university should lie in its role to advance scholarly learning through production and dissemination of high-quality knowledge, and the university press should materialize such a faith. (2) The scholarly books, though not the best media of scholarly communication taking a side view of its timeliness and brevity, can perform the function of the best media for the specific subject and readers. (3) The scholarly books as national resource must be published for the scholars demanding them even though the publication can't help depending on the subsidiary fund. (4) For the survival and activation of the university presses, the following strategies should be examined, and put in force if necessary. (a) The role of the foundation su n.0, pporting the university presses should be expanded (b) The Co-operative system among the operations of the presses should be established. (c) It is desirable that the university without the press should participate in the university with the press for both the financial su n.0, pporting and the publicizing its faculty's manuscripts. (d) The positive efforts should be made for the increase of sales copies by implementing the dual-system of publication. (e) It is desirable that 'recording system' should be incorporated in the traditional publication system both for the lightening of financial problems and the explosion of publications. (f) It is necessary that the effective methods of the bibliographical control should be developed for the improvement of the scholarly communication. (g) Any kind of the permanent organization composed of the representatives from all the infrastructures of information industry should be established to study the character and direction of technological changes and to discern the better choice of specific, technologies in the scholarly communication system.

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