• Title/Summary/Keyword: $4^{th}$ Generation

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Resistance Development and Cross-Resistance of Diamondback Moth (Lepidoptera: Plutellidae) by Single Selection of Several Insecticides (단제도태에 의한 배추좀나방(Plutella xylostella)의 약제저항성 발당과 교차저항성에 관한 연구)

  • 조영식;이승찬
    • Korean journal of applied entomology
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    • v.33 no.4
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    • pp.242-249
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    • 1994
  • These studles were conducted to investigate the development of chem~cal resistance and cross.resista. nce m dlarnondback moth (Piuteiia xylostella L). The resistance development of diamondback moth greatly vaned under single selection of five insectlades. The tnflumuron and lambda cyhalothnn strains at 8th selected generation showed 374- and 29.l.fold resistant levels. respectively, as compared with the susceptible strain. However, the Baciilus thuringiensis-seleded at 8th selected generatLon exhibited 240-fold resistant level. and the prothiophos-selected at 8th generation revealed 14.3-fold resistant !eve1 while the cartap hydrochloride-selected at 8th generailon showed 9.1-fold resistant level Prothiophos- selected strain showed low cross-resistance level to cartap hydrochloride, while this strain exhibited no cross-resistance of 1.3 to 2.8-fold to other msectlcides. Cartap hydrochlonde- seleded strain showed 19.9-fold. a high cross-resistance to lambda cyhalothrin, but this strain showed 2.2-34 fold, no cross resistance to other insecticide. Lambda cyhalothnn-selected strain exhibited cross-resistance to cartap hydrochlolide and prothiophas. Triflumuron-seleded strain showed 1.3-4.9 fold. no cross-resistance to other ~nsectic~dTe he B. ihuring~ensis-selededs train showed no cross-resistance to other insecticides.

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Preventive Effects of a Probiotic Mixture in an Ovalbumin-Induced Food Allergy Model

  • Shin, Hee-Soon;Eom, Ji-Eun;Shin, Dong-Uk;Yeon, Sung-Hum;Lim, Seong-Il;Lee, So-Young
    • Journal of Microbiology and Biotechnology
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    • v.28 no.1
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    • pp.65-76
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    • 2018
  • Although there has been a steady increase in the prevalence of food allergies worldwide in recent decades, no effective therapeutic strategies have been developed. Modulation of the gut microbiota composition and/or function through probiotics has been highlighted as a promising target for protection against food allergies. In this study, we aimed to investigate the allergy-reducing effects of a probiotic mixture (P5: Lactococcus lactis KF140, Pediococcus pentosaceus KF159, Lactobacillus pentosus KF340, Lactobacillus paracasei 698, and Bacillus amyloliquefaciens 26N) in mice with ovalbumin (OVA)-induced food allergy. Administration of P5 significantly suppressed the oral OVA challenge-induced anaphylactic response and rectal temperature decline, and reduced diarrhea symptoms. Moreover, P5 also significantly inhibited the secretion of IgE, Th2 cytokines (interleukin (IL)-4, IL-5, IL-10, and IL-13), and Th17 cytokines (IL-17), which were increased in mice with OVA-induced food allergy, and induced generation of CD4+Foxp3+ regulatory T cells. These results revealed that P5 may have applications as a preventive agent against food allergy.

Dopaminergic neuronal development in the embryonic mesencephalon of mouse

  • Kim, Mun-Ki;Lee, Si-Joon;Won, Chung-Kil
    • Korean Journal of Veterinary Research
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    • v.60 no.4
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    • pp.203-207
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    • 2020
  • This study presents neuronal migration pattern of dopamine (DA) neurons generated in separate regions occupying the ventral mesencephalic territory. A single pulse 5-bromodeoxyuridine (BrdU) was administered at embryonic day (E)10-E15. Distribution of tyrosine hydroxylase (TH) positive cells was determined at E13-postnatal day 0 (P0) by immunohistochemistry. BrdU positive cells labeled at E10 were spread out uniformly in the mesencephalon from E13 to E15, migrating through dorsal and ventral routes at E17 and P0. TH expression labeled at E10 was observed at E13 in the ventromedial region and clearly formed in the ventral tegmental area (VTA) at E15. At E17, TH expression in the substantia nigra (SN) was observed in the ventrolateral region, spreading more outward of the mesencephalon at P0. Generation of TH-positive cells labeled at E13 was also observed in VTA and SN of the mesencephalon at E17 and P0. The expression of these cells labeled after E15 was markedly decreased. These results demonstrated that an almost complete primary structure of DA neuron was formed at the early embryonic stage in the ventral mesencephalon, showing the most active neuronal migration was occurred at E13-E17.

Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages

  • Meyer J. Friedman;Haram Lee;June-Yong Lee;Soohwan Oh
    • IMMUNE NETWORK
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    • v.23 no.1
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    • pp.5.1-5.28
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    • 2023
  • Th cell lineage determination and functional specialization are tightly linked to the activation of lineage-determining transcription factors (TFs) that bind cis-regulatory elements. These lineage-determining TFs act in concert with multiple layers of transcriptional regulators to alter the epigenetic landscape, including DNA methylation, histone modification and threedimensional chromosome architecture, in order to facilitate the specific Th gene expression programs that allow for phenotypic diversification. Accumulating evidence indicates that Th cell differentiation is not as rigid as classically held; rather, extensive phenotypic plasticity is an inherent feature of T cell lineages. Recent studies have begun to uncover the epigenetic programs that mechanistically govern T cell subset specification and immunological memory. Advances in next generation sequencing technologies have allowed global transcriptomic and epigenomic interrogation of CD4+ Th cells that extends previous findings focusing on individual loci. In this review, we provide an overview of recent genome-wide insights into the transcriptional and epigenetic regulation of CD4+ T cell-mediated adaptive immunity and discuss the implications for disease as well as immunotherapies.

Optical Third-Harmonic Generation of Poly(2-Bromo-1,4-phenylenevinylene)

  • Hwang Do-Hoon;Lee Jeong-Ik;Lee Minyung;Shim Hong-Ku
    • Bulletin of the Korean Chemical Society
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    • v.15 no.1
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    • pp.25-28
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    • 1994
  • Weakly electron withdrawing bromine substituted poly(2-bromo-1,4-phenylenevinylene) (PBrPV) was synthesized th-rough water-soluble precursor method. The linear and nonlinear optical properties of PBrPV were compared with those of poly(1,4-phenylenevinylene) (PPV). The third-order nonlinear optical susceptibility, X^{(3)}$, was measured by using third-harmonic generation (THG) technique at 1907 nm, fundamental wavelength. The calculated $X^{(3)}$ values of PPV and PBrPV were 3${\times}$ 10$^{-12}$ esu and 2${\times}$10$^{-12}$ esu, respectively.

Design of a 4×4 Phased Array Antenna with High Sidelobe Charactericstic for Millimeter-Wave Band 5G Dedicated Network Services (밀리미터파 대역 5G 특화망 서비스를 위한 고부엽 특성의 4×4 위상배열안테나 설계)

  • Myeong-Jun Oh;Jung-Ick Moon;Jung-Nam Lee;Young-Bae Jung
    • Journal of IKEEE
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    • v.28 no.3
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    • pp.303-309
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    • 2024
  • This paper proposes a high-gain phased array antenna that can provide private network communication services for large office spaces, factories, and other large-scale facilities, specifically designed for millimeter-wave band 5G (5th generation) networks. The proposed antenna features a 4×4 array structure with eight sub-arrays, each consisting of a 1×2 series array. To achieve high side-lobe characteristics, an offset array structure is applied by shifting even-numbered rows by one unit, combined with power tapering to adjust the size of individual radiating elements. This design achieves a high side-lobe level (SLL) of 22.3 dB and a high gain of 18.1 dBi. Additionally, the antenna provides gain characteristics of at least 15.2 dBi and 17.4 dBi within the intended beam steering range of ±45° in the azimuth direction and ±10° in the elevation direction, ensuring smooth communication services over a wide service area.

Test and Analysis of Electromagnetic Compatibility in Next-Generation Train (차세대전동차 유도장애시험 및 분석)

  • Lee, Chang-Mu;Lee, Han-Min;Kim, Ju-Rak;Kim, Kil-Dong
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.2031-2036
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    • 2011
  • To leading subway technology Advanced Urban Transit System is developed by national research and development. Next-generation trains equipped with direct driving permanent magnet traction motor and individually controlled propulsion system. Electromagnetic properties of the Next-Generation Train from four perspectives will be discussed. The first is closely related to human hazards that affect the 60Hz low frequency electromagnetic field. The Second is inductive noise that affect railroad signal system. The third is conductive noise that affect communication line near railroad. The 4th is radiation noise that may affect electronic equipment near the railroad tracks.

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Constant Frequency Adjustable Power Active Voltage Clamped Soft Switching High Frequency Inverter using The 4th-Generation Trench-Gate IGBTs

  • Miyauchi T.;Hirota I.;Omori H.;Terai H.;Abdullah Al Mamun;Nakaoka M.
    • Proceedings of the KIPE Conference
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    • 2001.10a
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    • pp.236-241
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    • 2001
  • This paper presents a novel prototype of active voltage-clamping capacitor-assisted edge resonant soft switching PWM inverter operating at a constant frequency variable power (VPCF) regulation scheme, which is suitable for consumer high-power induction-heating cooking appliances. New generation IGBT with a trench gate is particularly improved in order to reduce conduction loss due to its lowered saturation voltage characteristics. The soft switching load resonant and quasi-resonant inverter designed distinctively using the latest IGBTs is evaluated from an experimental point of view.

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Feedforward Input Signal Generation for MIMO Nonminimum Phase Autonomous System Using Iterative Learning Method (반복학습에 의한 MIMO Nonminimum Phase 자율주행 System의 Feedforward 입력신호 생성에 관한 연구)

  • Kim, Kyongsoo
    • Journal of the Korea Institute of Military Science and Technology
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    • v.21 no.2
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    • pp.204-210
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    • 2018
  • As the 4th industrial revolution and artificial intelligence technology develop, it is expected that there will be a revolutionary changes in the security robot. However, artificial intelligence system requires enormous hardwares for tremendous computing loads, and there are many challenges that need to be addressed more technologically. This paper introduces precise tracking control technique of autonomous system that need to move repetitive paths for security purpose. The input feedforward signal is generated by using the inverse based iterative learning control theory for the 2 input 2 output nonminimum-phase system which was difficult to overcome by the conventional feedback control system. The simulation results of the input signal generation and precision tracking of given path corresponding to the repetition rate of extreme, such as bandwidth of the system, shows the efficacy of suggested techniques and possibility to be used in military security purposes.

Studies on the Malted red pepper catchup and Ginger of Chonla province (전라도(全羅道)의 생강(生薑)과 고추장에 관(關)한 연구(硏究))

  • Hwang, Ho-Gwan
    • Journal of the Korean Society of Food Culture
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    • v.3 no.4
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    • pp.351-357
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    • 1988
  • A feature of present fomula of dietary habitus is the result of its traditional succession, as like as the newly established culture is rooted in the inherited traditional culture. So, it is very important to discriminate the kind of korean traditional foods and to discuss the historical background of the foods in use, since they have to develope better dietary conditions in furture by using modern theory of dietetics. But there are few literatures concerning to korean traditional foods clear at a glance. However, some traditional foods including technology of cultivation and processing have been transmitted from generation to generation in some districts. Therefore, author has attempted to investigate the history of traditional foods. The results obtained were as follows. 1. A lots of traditional foods which were gifts to imperial court alloted to districts or civilian foods during Choson dynasty have been transmitted up to date, and the method of cultivation and processing are well preserved. Among them out standing examples are: 1) persimmon and its processed goods. 2) red pepper and malted pepper catchup. 3) ginger and its processed goods. 4) honey, bean sprouts etc. 2. It has been reported that ginger was cultivated in China in 5th century B.C. and in Korea early in 16th century. But historical relationships between them could not be confirmed. However, from SAMKUKSAGI and the report by Lee, Suk Woo(1754-1825) who was governor of Chonla province and remarked ginger as a sacred herb at Wanju county, Bongong town, it is suggested that ginger is a natural growing herb in Korea. 3. Soonchang malted pepper catchup is one of outstanding traditional foods which our ancestor have processed with red pepper. Peru is the place of origin, where they have cultivated pepper from 1st century. It is conceivable that pepper was transmitted from Europe to korea late in 16th century, and the first report on existence of pepper in korea was written in 1613. Therefore, it seems that malted red pepper catchup was processed 30 or 40 years later.

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