• Title/Summary/Keyword: ${99m}^Tc$

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Metastatic Calcification Revealed by Bone Scintigraphy; Case Report (전이성 석회화가 골 스캔에서 발견된 예)

  • Lee, Dong-Soo;Park, Sung-Ki;Lee, Myung-Chul;Cho, Bo-Youn;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.18 no.1
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    • pp.67-69
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    • 1984
  • A patient with multiple myeloma, hypercalcemia, and renal failure was found to have diffuse uptake of $^{99m}Tc-MDP$ in his both lungs and stomach. This finding appears to have been due to metastatic calcification of these organs.

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$^{99m}Tc-MDP$골스캔을 이용한 초기 골수염의 진단과 이의 평가

  • Lee, Sang-Rae;Kim, Won-Cheol
    • The Journal of the Korean dental association
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    • v.25 no.6 s.217
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    • pp.541-548
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    • 1987
  • 골수염은 조기에 적절한 치료를 하지않으면 중대한 후유증이 초래되므로 신속한 진단과 치료가 요구된다. 골수염을 진단하기 위해서는 구강검진, 방사선검사, 병리조직학적 검사, 혈액 및 세균배양검사와 골스캔등이 필요하다. 골수염의 감염과정은 골에 파괴적 및 재생적 변화의 양자를 모두 일으키지만 X선사진소견에서는 임상증상이 발현된 후 약 10내지 14일이 경과되어야만 골변화를 관찰할 수 있으며 그 이전에는 대체로 비특이적 연조직의 종창만을 보인단. 반면에 골스캔을 이용하면 급성염증기의 골질환을 감견하기가 용이하다. 골스캔제의 국소골섭취의 증가는 골의 어떤 부위에서 대사능이나 혈류가 증가된 경우에 일어나기 때문에, 실제로 임상증상이 발현된 후 24시간정도의 조기에 골스캔상은 양성반응을 보인다. 즉 골의 국소적 병변은 어느정도 신생골 형성과 골파괴가 같이 수반되어있고 이러한 신생골은 골스캔제와 친화력이 강하므로 골형성반응을 야기하는 어떠한 병변이라도 골스캔에 의하여 발견될 수 있다. 임상적으로 골수염에 대하여 골스캔을 시행하는 경우는 골수염의 조기진단, 골수염과 봉와직염과의 감별진단, 만성 공수염의 악화여부 및 치료에 대한 반응을 monitoring하기 위해서 시행된다.

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Salivary Scan Findings and Excretion Rate in $Sj\"{o}gren$ Syndrome ($Sj\"{o}gren$ Syndrome에서 타액선 스캔 소견과 타액 제거율에 관한 연구)

  • Lee, Myung-Hae;Chung, June-Key;Lee, Myung-Chul;Cho, Bo-Youn;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.22 no.1
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    • pp.33-37
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    • 1988
  • Salivary scan and stimulated salivary clearance of $^{99m}Tc-pertechnetate$ was performed in 11 pateients with $Sj\"{o}gren$ syndrome (group I), 4 patients with rheumatoid arthritis (group II), 8 patients with non-connective tissue diseases (group III) and 9 normal controls. Stimulated salivary clearances of pertechnetate of normal controls, group II and group III were in normal range (over 16.5 ml/min) and that of patients with $Sj\"{o}gren's$ syndrome was significantly reduced (11.1 ml/min).

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Photon Defects due to Residual Barium in the Colon Simulating Cold Bone Metastasis in Two Patients with Extraskeletal Cancer (골격외 종양 환자에서 냉소 골전이와 유사하게 보인 잔류 바리움에 의한 광자 결손)

  • Lim, Seok-Tae;Kim, Min-Woo;Sohn, Myung-Hee
    • The Korean Journal of Nuclear Medicine
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    • v.36 no.5
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    • pp.314-316
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    • 2002
  • One of common causes of cold defects on bone scintigraphy is an attenuation artifact. Cold defects can be produced by belt buckles, buttons, earring, necklaces, or other metal objects. Cold lesions in the abdomen are also produced by retained barium in the gastrointestinal tract after recent barium studies. We observed artifacts due to retained barium in the colon on bone scintigraphy, which simulated cold bone metastases in two patients with extraskeletal cancer.

Molecular imaging of atherosclerosis using reporter gene system

  • Yoo, Ran Ji;Lee, Kyochul;Kang, Joo Hyun;Lee, Yong Jin
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.4 no.1
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    • pp.26-31
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    • 2018
  • Macrophages play a key role in atherosclerotic plaque formation, but their participation has been discerned largely via ex vivo analyses of atherosclerotic lesions. Therefore, we aimed to identify atherosclerosis on noninvasive in vivo imaging using reporter gene system. This study demonstrated that recruitment of macrophages could be detected in atherosclerotic plaques of Apolipoprotein E knockout (ApoE-/-) mice with a sodium iodide symporter (NIS) gene imaging system using $^{99m}Tc-SPECT$. This novel approach to tracking macrophages to atherosclerotic plaques in vivo could have applications in studies of arteriosclerotic vascular disease.