• Title/Summary/Keyword: ${131}^I$

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Marital Status, Health Behaviors and Health Status for Middle-Aged Men and Women in Korea (혼인상태에 따른 중년남녀의 건강행위와 건강상태)

  • Lee, Yun-Suk
    • Korea journal of population studies
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    • v.35 no.2
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    • pp.103-131
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    • 2012
  • As divorce and singlehood have been on the rise over the last decades, marital statuses are more diverse than the past for middle-aged men and women in South Korea. While marital status is crucial for health behaviors and statuses, but few studies examine the associations between health differentials and marital status for the middle-aged in South Korea. Using the 2010 Social Survey collected by the Statistics Korea, this study analyzes how health behaviors and statuses vary by the marital status. In particular, this paper examines whether marital statuses and gender interact to influence health behaviors and statuses. I find that married middle-aged people are healthier than divorced, single, and widowed middle-aged people. But this the negative influence of the non-married status are much greater for men than women. Some female non-married groups do not differ from married middle-aged people in some indicators of health behaviors. Single female middle-aged people are better in general satisfaction levels than married middle-aged people.

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Experience and perception of sexual harassment during clinical practice among dental hygiene students (치위생(학)과 학생의 성희롱 인식 및 임상실습 시 성희롱 경험 실태)

  • Cho, Hye-Eun;Lee, Bo-Ram
    • Journal of Korean society of Dental Hygiene
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    • v.18 no.6
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    • pp.1003-1012
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    • 2018
  • Objectives: The purpose of this study was to contribute to the provision of a safe practice environment and practical sexual harassment prevention education for dental hygiene students who practice clinically. Methods: A total of 260 students with experience in clinical practice at dental hygiene colleges and universities in Gwangju and Jeonnam was included in this study. From May 1, 2018 to June 30, 2018, subjects were surveyed about sexual harassment experience, sexual harassment related information, self-esteem, and self-assertiveness. Statistical analysis was performed by frequency analysis, independent t-test, Mann-Whitney test, one way ANOVA, Pearson's correlation analysis, and multiple regression analysis. Results: In the sexual harassment survey revealed that 64.3% of offenders were patients and 50.0% of the offenders were in their 40s. A total of 78.6% of the offenders reported harassment in hospital type "dental clinics." Most respondents disclosed that "I did not do anything" (60.7%). Psychologically, 75.0% felt "shame and insult." Self-esteem was high in the fourth grade (3.68). Self-esteem and self-assertiveness were higher among those with no sexual harassment experiences (131.77 and 132.81, respectively; p<0.05). Correlation analysis indicated that self-esteem and self-assertiveness were correlated (r=0.509, p<0.01). Factors influencing the perception of sexual harassment include: three to four months of clinical practice (${\beta}=0.361$), experience of sexual harassment (${\beta}=-0.551$), and self-esteem (${\beta}=0.503$). Conclusions: It is necessary to provide systematic and diverse information to address sexual harassment. A proper perception of what constitute sexual harassment in clinical practice is also relevant. Furthermore, practical sexual harassment prevention education program should be developed and implemented.

Differences in mandibular condyle and glenoid fossa morphology in relation to vertical and sagittal skeletal patterns: A cone-beam computed tomography study

  • Noh, Kyoung Jin;Baik, Hyoung-Seon;Han, Sang-Sun;Jang, Woowon;Choi, Yoon Jeong
    • The korean journal of orthodontics
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    • v.51 no.2
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    • pp.126-134
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    • 2021
  • Objective: This study aimed to evaluate the following null hypothesis: there are no differences in the morphology of the temporomandibular joint (TMJ) structures in relation to vertical and sagittal cephalometric patterns. Methods: This retrospective study was performed with 131 participants showing no TMJ symptoms. The participants were divided into Class I, II, and III groups on the basis of their sagittal cephalometric relationships and into hyperdivergent, normodivergent, and hypodivergent groups on the basis of their vertical cephalometric relationships. The following measurements were performed using cone-beam computed tomography images and compared among the groups: condylar volume, condylar size (width, length, and height), fossa size (length and height), and condyle-to-fossa joint spaces at the anterior, superior, and posterior condylar poles. Results: The null hypothesis was rejected. The Class III group showed larger values for condylar width, condylar height, and fossa height than the Class II group (p < 0.05). Condylar volume and superior joint space in the hyperdivergent group were significantly smaller than those in the other two vertical groups (p < 0.001), whereas fossa length and height were significantly larger in the hyperdivergent group than in the other groups (p < 0.01). The hypodivergent group showed a greater condylar width than the hyperdivergent group (p < 0.01). The sagittal and vertical cephalometric patterns showed statistically significant interactions for fossa length and height. Conclusions: TMJ morphology differed across diverse skeletal cephalometric patterns. The fossa length and height were affected by the interactions of the vertical and sagittal skeletal patterns.

High-Performance Compton SPECT Using Both Photoelectric and Compton Scattering Events

  • Lee, Taewoong;Kim, Younghak;Lee, Wonho
    • Journal of the Korean Physical Society
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    • v.73 no.9
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    • pp.1393-1398
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    • 2018
  • In conventional single-photon emission computed tomography (SPECT), only the photoelectric events in the detectors are used for image reconstruction. However, if the $^{131}I$ isotope, which emits high-energy radiations (364, 637, and 723 keV), is used in nuclear medicine, both photoelectric and Compton scattering events can be used for image reconstruction. The purpose of our work is to perform simulations for Compton SPECT by using the Geant4 application for tomographic emission (GATE). The performance of Compton SPECT is evaluated and compared with that of conventional SPECT. The Compton SPECT unit has an area of $12cm{\times}12cm$ with four gantry heads. Each head is composed of a 2-cm tungsten collimator and a $40{\times}40$ array of CdZnTe (CZT) crystals with a $3{\times}3mm^2$ area and a 6-mm thickness. Compton SPECT can use not only the photoelectric effect but also the Compton scattering effect for image reconstruction. The correct sequential order of the interactions used for image reconstruction is determined using the angular resolution measurement (ARM) method and the energies deposited in each detector. In all the results of simulations using spherical volume sources of various diameters, the reconstructed images of Compton SPECT show higher signal-to-noise ratios (SNRs) without degradation of the image resolution when compared to those of conventional SPECT because the effective count for image reconstruction is higher. For a Derenzo-like phantom, the reconstructed images for different modalities are compared by visual inspection and by using their projected histograms in the X-direction of the reconstructed images.

Dose Estimation Model for Terminal Buds in Radioactively Contaminated Fir Trees

  • Kawaguchi, Isao;Kido, Hiroko;Watanabe, Yoshito
    • Journal of Radiation Protection and Research
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    • v.47 no.3
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    • pp.143-151
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    • 2022
  • Background: After the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, biological alterations in the natural biota, including morphological changes of fir trees in forests surrounding the power plant, have been reported. Focusing on the terminal buds involved in the morphological formation of fir trees, this study developed a method for estimating the absorbed radiation dose rate using radionuclide distribution measurements from tree organs. Materials and Methods: A phantom composed of three-dimensional (3D) tree organs was constructed for the three upper whorls of the fir tree. A terminal bud was evaluated using Monte Carlo simulations for the absorbed dose rate of radionuclides in the tree organs of the whorls. Evaluation of the absorbed dose targeted 131I, 134Cs, and 137Cs, the main radionuclides subsequent to the FDNPP accident. The dose contribution from each tree organ was calculated separately using dose coefficients (DC), which express the ratio between the average activity concentration of a radionuclide in each tree organ and the dose rate at the terminal bud. Results and Discussion: The dose estimation indicated that the radionuclides in the terminal bud and bud scale contributed to the absorbed dose rate mainly by beta rays, whereas those in 1-year-old trunk/branches and leaves were contributed by gamma rays. However, the dose contribution from radionuclides in the lower trunk/branches and leaves was negligible. Conclusion: The fir tree model provides organ-specific DC values, which are satisfactory for the practical calculation of the absorbed dose rate of radiation from inside the tree. These calculations are based on the measurement of radionuclide concentrations in tree organs on the 1-year-old leader shoots of fir trees. With the addition of direct gamma ray measurements of the absorbed dose rate from the tree environment, the total absorbed dose rate was estimated in the terminal bud of fir trees in contaminated forests.

Feature Extraction and Evaluation for Classification Models of Injurious Falls Based on Surface Electromyography

  • Lim, Kitaek;Choi, Woochol Joseph
    • Physical Therapy Korea
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    • v.28 no.2
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    • pp.123-131
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    • 2021
  • Background: Only 2% of falls in older adults result in serious injuries (i.e., hip fracture). Therefore, it is important to differentiate injurious versus non-injurious falls, which is critical to develop effective interventions for injury prevention. Objects: The purpose of this study was to a. extract the best features of surface electromyography (sEMG) for classification of injurious falls, and b. find a best model provided by data mining techniques using the extracted features. Methods: Twenty young adults self-initiated falls and landed sideways. Falling trials were consisted of three initial fall directions (forward, sideways, or backward) and three knee positions at the time of hip impact (the impacting-side knee contacted the other knee ("knee together") or the mat ("knee on mat"), or neither the other knee nor the mat was contacted by the impacting-side knee ("free knee"). Falls involved "backward initial fall direction" or "free knee" were defined as "injurious falls" as suggested from previous studies. Nine features were extracted from sEMG signals of four hip muscles during a fall, including integral of absolute value (IAV), Wilson amplitude (WAMP), zero crossing (ZC), number of turns (NT), mean of amplitude (MA), root mean square (RMS), average amplitude change (AAC), difference absolute standard deviation value (DASDV). The decision tree and support vector machine (SVM) were used to classify the injurious falls. Results: For the initial fall direction, accuracy of the best model (SVM with a DASDV) was 48%. For the knee position, accuracy of the best model (SVM with an AAC) was 49%. Furthermore, there was no model that has sensitivity and specificity of 80% or greater. Conclusion: Our results suggest that the classification model built upon the sEMG features of the four hip muscles are not effective to classify injurious falls. Future studies should consider other data mining techniques with different muscles.

Risk Analysis and Safety Assessment of Microbiological and Chemical Hazards in Katsuobushi Products Distributed in the Market (시중에서 유통되는 가쓰오부시의 미생물학적·화학적 위해요소분석 및 안전성 평가)

  • Song, Min Gyu;Kim, So Hee;Kim, Jin Soo;Lee, Jung Suck;Heu, Min Soo;Park, Shin Young
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.4
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    • pp.431-436
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    • 2022
  • For the safety assessment of microbiological and chemical hazards in katsuobushi, fifteen samples of katsuobushi were purchased from supermarkets. The contamination levels of total viable bacteria, coliforms, Escherichia coli, and nine pathogenic bacteria [Staphylococcus aureus, Salmonella spp., Listeria monocytogenes, Bacillus cereus, Vibrio parahaemolyticus, Clostridium perfringens, Enterohemorrhagic E. coli (EHEC), Yersinia enterocolitica and Campylobacter jejuni/coli] were quantitatively or qualitatively assessed. Additionally, the heavy metals (total and methyl mercury) content, radioactivity (131 I, 134 Cs+ and 137 Cs) were quantitatively assessed. Microbial and chemical analyses were performed using standard methods in Korean food code. The contamination level of total viable bacteria was 2.70 (1.18-4.42) log CFU/g. Coliforms, E. coli and S. aureus were not detected in any samples. Other eight pathogenic bacteria were negative in all samples. The contamination levels of total and methyl mercury were 0.366 (0.227-0.481) and 0.120 (0.002-0.241) mg/kg, respectively. In addition, radioactivity was not detected in any samples. The results will be helpful in revitalizing domestic use and boosting exports of katsuobushi because the microbiological and chemical safety of katsuobushi has been assured. Furthermore, the results may be used as a basis for performing chemical and microbial risk assessments of katsuobushi.

Studies on the Bituminization Process of Radioactive Liquid Waste[I]

  • Lee, Sang-Hoon;Chun, Kwan-Sik;Lim, Eung-Keuk
    • Nuclear Engineering and Technology
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    • v.7 no.3
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    • pp.213-222
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    • 1975
  • Immobilization of the second-cycle radioactive liquid wastes from a Purex process was developed with the blown asphalt (manufactured by Kukdong Shell Oil Company Ltd) to eliminate the possibility that the radioactive materials will be redispersed into the environment. Attempts to incorporate these wastes directly into the asphalt martrices without any pretreatment were not successful, as it was observed that the sulphuric acid in the waste oxidised the asphalt. Hence, the waste was treated with caustic soda and made alkaline prior to bituminization, so that it was found that this pretreatment made the waste compatible to the asphalt matrices. The pure blown asphalt samples irradiated with doses of 4.0$\times$10$^{7}$ rad showed no evidence of volume increase. The suitable temperature for incorporation of the alkaline wastes into blown asphalt was 180-20$0^{\circ}C$. The Products containing 50 wt% salts represented the following good properties viz., volume reduction (about 1.4), homogeneity, teachability etc. During the period of 131 day $s^{l37}$Cs from products containing 40wt% salts was leached at rates ranging from 2.70$\times$10-4 to 8.27$\times$10-4g/cm2_day but the rate for $^{90}$ Sr was lower by one to two orders of magnitude by distilled water. The leaching rates for $^{137}$ Cs and $^{90}$ Sr by sea water were slightly lower than by distilled water. Both of the leaching rates decreased with increasing pH.H.

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Synthesis of a PEGylated tracer for radioiodination and evaluation of potential in tumor targeting

  • Abhinav Bhise;Sushil K Dwivedi;Kiwoong Lee;Jeong Eun Lim;Subramani Rajkumar;Woonghee Lee;Seong Hwan Cho;Jeongsoo Yoo
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.7 no.2
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    • pp.79-84
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    • 2021
  • Radiopharmaceuticals are important for tumor diagnosis and therapy. To deliver a radiotracer at the desired target excluding non-targeted tissues is difficult The development of a targeted tracer that has a good clearance profile while maintaining high biostability and biocompatibility is key to optimizing its biodistribution and transport across biological barriers. Improving the hydrophilicity of radiotracers by PEGylation can reduce serum binding, allowing the tracer to circulate without retention and reducing its affinity for non-targeted tissues. In this study, we synthesized a new benzamido tracer (SnBz-PEG36) with the introduction of a low molecular weight polyethylene glycol unit (PEG36, ~2,100 Da). The tumor targeting efficiency and biodistribution of [131I]-Bz-PEG36 or radiotracer-loaded liposomes were evaluated after their administration to normal mice or mouse tumor models including CT26 (xenograft) and 4T1 (xenograft and orthotopic). Most of the radiotracer was cleared out rapidly (1-24 h post-administration) through the kidney and there was little tumor uptake.

PSMA Inhibitors for Nuclear Imaging and Radiotherapy of Prostate Cancer

  • Sajid Mushtaq;Tugsuu Uyanga;Park Ji Ae;Jung Young Kim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.9 no.1
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    • pp.23-33
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    • 2023
  • Prostate cancer ranks as the world's second most frequently diagnosed cancer among men, and is responsible for the fifth highest number of cancer-related deaths in this population. The development of effective diagnostic and therapeutic approaches for prostate cancer remains a major challenge in the field of oncology. Over the past few years, the prostate-specific membrane antigen (PSMA) has raised as a hopeful tracer for the diagnosis and treatment of prostate cancer.Various radioisotopes, such as 131I, 99mTc, 68Ga, and 177Lu, have been used to label PSMA analogues, with varying degrees of success. Among these, 68Ga-PSMA-11 and 177Lu-PSMA-617 have emerged as the most promising radioligands for clinical use. Recently, researchers have been exploring the use of other radioisotopes, such as 211At, 89Zr, 64/67Cu, and 203/212Pb, for the labeling of PSMA-targeted radioligands. These radioisotopes have unique properties that may offer advantages over existing radioligands, such as longer half-lives, higher specific activities, and different emission profiles. Efforts are currently underway to develop these radiopharmaceuticals and make them more widely available for clinical use. These exciting developments highlight the potential of PSMA-targeted radioligands for the diagnosis and treatment of prostate cancer, and provided significant implications for the management of this disease in the future. The current study aims to provide a comprehensive summary of the latest research and clinical applications of radiolabeled PSMA inhibitors for diagnoses and therapy of prostate cancer, emphasizing the exciting developments in the field and their potential impact on clinical practice.