• 한국주거학회논문집
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• 제18권1호
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• pp.131-139
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• 2007

The aim of this paper is to find out different preference of common spaces and shared activities in senior cohousing community between regions in Korea: Seoul and other cities. Social survey was conducted nationwide and the respondents were 50s only, since they are the generation who will face to elderly housing subject within 10 years in turbulent Korean society. Collected data, about 1000, were analyzed by SPSS program using frequency, percentage, and Chi-square test. In summary, respondents mostly would like to move to senior cohousing on circumstance when they remain alone without big difference between regions. Loneliness and housekeeping were considered as the most difficult issues for the elderly to manage by themselves. Among common spaces, exercise room was the most preferred space to meeting room and kitchen. Exercise room was more preferred in Seoul than in other cities, on the contrary meeting room was evidently less preferred in other cities than in Seoul. Regarding shared activities, resident meeting, gardening, and common meal were revealed as less preferred activities than hobby exercise and tea meeting. As a conclusion, I would like to propose that a big common living room is better to be designed for meeting room cum dining and gathering room with flexibility in order to give residents chances to know each other more often. And since common space and shared activity show different preferences by regions, those are to be designed and planned reflecting region's different circumstance.

• The Korean Journal of Ceramics
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• 제5권4호
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• pp.336-340
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• 1999

Glasses in the system $CaO-TiO_2-SiO_2-Al_2O_3-ZrO_2-B_2O_3$ were investigated to find the glass seal compositions suitable for use in the planar solid oxide fuel cell (SOFC). Glass-ceramics prepared from the glasses by one-stage heat treatment at $1,000^{\circ}C$ showed various thermal expansion coefficients (i,e., $8.6\times10^{-6^{\circ}}C^{-1}$ to $42.7\times10^{-6^{\circ}}C^{-1}$ in the range 25-$1,000^{\circ}C$) due to the viscoelastic response of glass phase. The average values of contact angles between the zirconia substrate and the glass particles heated at 1,000-$1,200^{\circ}C$ were in the range of $131^{\circ}\pm4^{\circ}$~$137^{\circ}\pm9^{\circ}$, indicating that the glass-ceramic was in partial non-wetting condition with the zirconia substrate. With increasing heat treatment time of glass samples from 0.5 to 24 h at $1,100^{\circ}C$, the DC electrical conductivity of the resultant glass-ceramics decreased from at $800^{\circ}C$. Isothermal hold of the glass sample at $1100^{\circ}C$ for 48h resulted in diffusion of Ca, Si, and Al ions from glass phase into the zirconia substrate through the glass/zirconia bonding interface. Glass phase and diffusion of the moving ion such as $Ca^{2+}$ in glass phase is responsible for the electrical conduction in the glass-ceramics.

• 한국환경성돌연변이발암원학회지
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• 제15권2호
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• pp.131-139
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• 1995

Air suspedned particulates are the most serious factor among air pollutants in Seoul and their extracts have been revealed to be pulmonary carcinogenes. Air particulates were collected at a site representative of the high traffic area of Seoul from December 1993 to May 1994. Polycyclic aromatic hydrocarbons (PAHs) and nitroarenes in organic extracts of air particulates were determined by gas chromatography and mutagenicity of particle extracts was evaluated by the pre-incubation procedure with Salmonella typhirnurium TA98 and TA 98NR. The average concentration of total suspended particulates and inhalable (less than 10 $\mu$m) particulates were 169.63 $\mu g/m^3$, 141.92 $\mu g/m^3$, respectively. The relative contribution of organic matters was highest in neutral fraction and was lowest in basic fraction. Among identified 20 PAHs, the level of PAHs with 4-benzen ring i.e., pyrene, benzo(a)anthracene and chrysene were much higher than the PAHs with higher ring numbers. The mutagenicity of air particulates was much higher in the presence of rat liver microsomai fraction (S9 mixture) than that observed in its absence, which indicates that air particulates contained both direct and indirect mutagens. Nitroarenes in this study were not almost detected but mutagenicity of their fraction was higher. These results are represent to research for the identification of nitroarenes in the forward study.

• 대한가정학회지
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• 제27권3호
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• pp.79-87
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• 1989

As the level of life improves, the pattern of beverage comsumption are being changed. We came to drink more beverage than ever before, and I think, the remarkable increase of beverage consumption will have a great effect on our health. We examined the drinking pattern of 447 middle school and high school students in Taejeon City from 24 to 29, May, 1989. We studied about the amount of drinking beverage and the correlation between the amount and the various factors to have effects on the amount. They usually drink total 604.6ml/day, water 292.8ml, soft drink 131.8ml, milk 109.2ml, fruit juice 26.1ml, vegetable juice 9.6ml, coffee & tea 21.7ml, korean tea 15.4ml. Beside, middle school students drink 654.4ml and high school students drink 560.7ml. The male drink 620.1ml and the female drink 589.2ml. The average amount of beverage consumption per a unit weight is total 13.3ml and middle school students (654.3ml) drink more than high school students (560.7ml) but the average amount is same between the male and the female. They usually drink 343.5ml of beverage at their homes, and they drink more at their homes than away from homes. In addition, at the correlation between the amount of drinking beverage and the various factor to have effects on the amount, the students who have snacks very often drink more than those who don't. And the students who like meat-diet drink much more than meat & vagetabe-diet persons and vegetorians. And the students who eat pread often drink more than those who have rice at every mealtime.

• 대한핵의학회지
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• 제38권2호
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• pp.152-160
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• 2004

Radioiodide uptake in thyroid follicular epithelial cells, mediated by a plasma membrane transporter, sodium iodide symporter (NIS), provides a first step mechanism for thyroid cancer detection by radioiodide injection and effective radioiodide treatment for patients with invasive, recurrent, and/or metastatic thyroid cancers after total thyroidectomy. NIS gene transfer to tumor cells may significantly and specifically enhance internal radioactive accumulation of tumors following radioiodide administration, and result in better tumor control. NIS gene transfers have been successfully performed in a variety of tumor animal models by either plasmid-mediated transfection or virus (adenovirus or retrovirus)-mediated gene delivery. These animal models include nude mice xenografted with human melanoma, glioma, breast cancer or prostate cancer, rats with subcutaneous thyroid tumor implantation, as well as the rat intracranial glioma model. In these animal models, non-invasive imaging of in vivo tumors by gamma camera scintigraphy after radioiodide or technetium injection has been performed successfully, suggesting that the NIS can serve as an imaging reporter gene for gene therapy trials. In addition, the tumor killing effects of I-131, ReO4-188 and At-211 after NIS gene transfer have been demonstrated in in vitro clonogenic assays and in vivo radioiodide therapy studies, suggesting that NIS gene can also serve as a therapeutic agent when combined with radioiodide injection. Better NIS-mediated imaging and tumor treatment by radioiodide requires a more efficient and specific system of gene delivery with better retention of radioiodide in tumor. Results thus far are, however, promising, and suggest that NIS gene transfer followed by radioiodide treatment will allow non-invasive in vivo imaging to assess the outcome of gene therapy and provide a therapeutic strategy for a variety of human diseases.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1859-1862
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• 2014

Recently, the main therapy of medullary thyroid cancer (MTC) is surgical, but by which way there is a poor prognosis with a mean survival of only 5 years. In some cases, some researchers found that it is the medullary thyroid cancer stem cells (MTCSCs) that cause metastasis and recurrence. This study aimed to eradicate MTCSCs through administration of all-trans-retinoic acid (ATRA). Here we demonstrate that MTCSCs possess stemlike properties in serum-free medium. The ABCG2, OCT4 and sodium iodide symporter (NIS) were changed by ATRA. Additionally, we found that ATRA can increase the expression of NIS in vivo. All the data suggested that ATRA could increase the iodine uptake of MTCSCs through NIS.

• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.116-131
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• 2007

황기건중탕은 보비익기(補裨益氣) 및 거습열(祛濕熱)하는 효능(效能)으로 신체(身體)의 허약(虛弱)을 개선하며 염증(炎症)을 유발할 수 있는 외사(外邪)의 침입을 방어하여 인체의 면역기능(免疫機能)을 강화하는 처방으로 면역관련 세포중 하나인 microglial cell를 대상으로 면역세포에 황기건중탕이 어떠한 효능을 발휘하는 지를 살펴보았다. 물로 전탕(煎湯)한 황기건중탕을 여과한 후 실험한 결과 BV2 microglial cells에서 LPS로 자극하여 염증을 유발하는 주요 물질인 NO의 분비를 세포독성 없이 억제하였다. 또한NO를 생성하는 효소인 Cox-2의 발현도 감소시켰다. 그리고 기타 염증전구 물질들이 $TNF-{\alpha}$, $IL-1{\beta}$, IL-12도 황기건중탕의 용량이 증가함에 따라 의존적으로 감소함을 알 수 있었다. 이러한 결과를 보아 황기건중탕은 면역관련세포인 microglial cell에서 염증 관련 인자들의 분비 및 생성을 억제를 통하여 면역관련 상태를 개선시키는 것으로 사료된다.

• 한국작물학회지
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• 제35권2호
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• pp.126-131
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• 1990

양적 형질을 중심으로 다변량 해석법에 의해 율무품종들 간의 유전적 거리를 추정하고 이에 기초한 Cluster analysis를 실시하여 품종을 분류한 결과는 다음과 같다. 1. Mahalanobis's distance(D$^2$)에 의하여 공시한 62개 품종을 10개군으로 대별해 볼 수 있었는데 1개 품종만으로 군을 형성한 제V군을 제외하고는 모든 품종이 고른군을 형성하였다. 2. 제I군에 3품종(5%), 제II군에 18품종(29%), 제III군에 5품종(8%), 제IV군에 13품종(21%), 제V군에 1품종(2%), 제Ⅵ군에 5품종(8%), 제Ⅶ5군에 7품종(11%), 제Ⅷ군에 4품종(7%), 제Ⅸ군에 2품종(3%) 그리고 제Ⅹ군에 4품종(7%)이 소속되어 있으며 제II군과 IV군은 여타 형질면에 상당한 변이폭을 가진 반면 제Ⅷ-Ⅹ군은 단간종으로 초세나 수량형질면에서 변이폭이 좁고 다소 렬세인 경향이었다. 3. 지리적 분포와 유전적 변이는 직접관련이 없는 것으로 평가되었다. 4. 품종군내, 품종군간의 D$^2$에 가장 큰 영향을 미친 형질은 개화기, 성숙기, 초장, 등숙율, 립수이었다.

• 동의신경정신과학회지
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• 제11권1호
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• pp.131-143
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• 2000

This study was aimed to get the course which is caused by Neuropsychiatric symptoms in Sang-Han. Therefore this study is based on ${\ulcorner}Euhak-Ipmun\;Sang-Han{\lrcorner}$(${\ulcorner}$醫學入門\;傷寒${\lrcorner}$) classfied mainly by symptoms. The results were summerized as follows: 1. Neuropsychiatric symptoms in ${\ulcorner}Euhak-Ipmun\;Sang-Han{\lrcorner}$(${\ulcorner}$醫學入門\;傷寒${\lrcorner}$) are explained as Pal-Gang(八綱), which shows those are settled down to a systematic oriental medical theory. 2. Pal-Bup (八法) is used in the cure of symptomatische psychose in Euhak-Ipmun${\cdot}$Sang-Han (醫學入門${\cdot}$傷寒), which is intended to boost the effect of cure, choosing the respondent cure method about various causes. 3. PaI-Gang(八綱) and Pal-Bup(八法) in ${\ulcorner}Euhak-Ipmun\;Sang-Han{\lrcorner}$(${\ulcorner}$醫學入門;傷寒${\lrcorner}$) are improved by Lee-Chun who added Jang-Gi(張機)'s Sang Han theory and new medical thought in the ages of Geum Won. 4. Lee-Chun believed that Neuropsychiatric symptoms which appeared in Sang Hang is caused by the ‘Unbalance(不平)’. So he wanted to reach harmony of ‘Jeong(精), Qi(氣), Shin(神), Hyul(血)’ after improving the status of $‘Unbalance(\;{\ulcorner}不平{\lrcorner})’$ toward the status of ‘Balance(平)’.

• 식물조직배양학회지
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• 제22권3호
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• pp.131-135
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• 1995

잡종 사기나무의 기내 대량증식을 목적으로 줄기절간 유래의 기내 및 기외시료를 이용하여 다경줄기 유도에 관여하는 식물생장 조절물질의 효과에 대하여 조사하였다. 기외시료의 측아를 제거한 다음 20에서 30$\mu$M 의 zeatin이 함유된 WPM 배지에 6주간 배양하였을때 각각 11개와 13개의 다경줄기가 유도되었다. 그러나 기외시료의 측아가 붙어있는 상태에서 기내배양하여 2주후에 측아를 제거하고 동일 배지에 배양하였을 경우에는 BA가 1.0에서 2.0 $\mu$M 함유된 배지에서도 13개와 15개의 다경줄기를 유도할 수 있었으며, 특히 이때 생산된 줄기의 상태는 아주 건전한 것으로 나타났다. 기내줄기를 사용하였을때는 20 $\mu$M의 zeatin을 처리하였을때 가장 많은 줄기를 생산할 수 있었으며, 생산된 조직배양묘는 일정기간 순화를 시킨 후 온실이나 포지에 식재가 가능하였다.