• 제목/요약/키워드: ${131}^I$

검색결과 1,078건 처리시간 0.028초

가습화한 고유량의 이산화탄소가스 통기가 관상동맥 내피세포층에 미치는 영향 (Effect of Humidified High Flow CO2 Gas Insufflation on the Coronary Endothelium)

  • 최재성;김준성;서정욱;김기봉
    • Journal of Chest Surgery
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    • 제37권2호
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    • pp.131-138
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    • 2004
  • 이공심폐기를 사용하지 않는 관상동맥 우회술에서 출혈로부터 수술시야를 확보하기 위해 사용하는 고유량의 가스 통기는 관상동맥 내피세포에 나쁜 영향을 미칠 수 있다. 본 연구에서는 이산화탄소 가스 통기가 유량에 따라서 관상동맥 내피세포에 다른 영향을 미치는가를 규명하고, 가습의 추가가 관상동맥 내피세포에 보호효과를 나타내는지를 평가하고자 하였다. 대상 및 방법: 돼지(n=9)를 이용하여 정중흉골 절개 후 좌전하 관상동맥을 노출한 후 4개의 분절로 나누어, 심박동 상태에서 각각의 관상동맥 분절에 절개를 가한 후, 가장 원위부 분절은 가스통기 없이 10분간 노출하였고(대조군), 다음 원위부 분절은 가습 없이 5 L/min의 유량으로(I군), 중앙 분절은 가습하면서 5 L/min의 유량으로 (II군), 근위부 분절은 가습하면서 10 L/min의 유량으로(III군) 각각 10분간 절개부위에 이산화탄소를 통기하였다. 관상동맥 분절들을 적출 후 내피세포층의 손상 정도를 평가하기 위해 hematoxyline-eosin 염색, 특수염색인 탄력섬유 염색, CD34 monoclonal antibody를 이용한 면역염색 등을 시행하고 전자현미경을 통하여 관상동맥 내막의 미세구조를 관찰하였다. 결과: I, II, III군 모두에서 내탄력판은 손상없이 온전하였으나 관상동맥 내피세포층은 모두에서 유의한 손상이 관찰되었다. 내피세포의 평균 잔존비율은 각각 I군이 20.9$\pm$16.7%, II군이 39.3$\pm$19.6%, III군이 6.8$\pm$5.3%로, II군이 다른 군들에 비해서 통계적으로 유의하게 높았으며(p=0.008), I군은 III군보다 유의하게 높았다. 결론: 이상의 결과로 이산화탄소 가스 통기로 인한 관상동맥 손상의 정도는 주로 통기 가스의 유량에 달려있으며, 10 L/min 이상의 고유량의 이산화탄소 가스 통기 시에는 가습을 하더라도 관상동맥 내피세포층의 보호효과를 기대하기 힘들다고 할 수 있다.

어레이 압저항 센서를 활용한 체질맥 임상연구 (Clinical Study on the Sasang Constitutional Pulse Using Array Piezoresistive Sensor)

  • 이시우;주종천;김경요;김종열
    • 사상체질의학회지
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    • 제18권1호
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    • pp.118-131
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    • 2006
  • 1. Objective Pulse diagnosis is generally applied to Traditional Oriental Medicine but not to Sasang Constitution diagnosis. Recently new pulse analyzer using array piezoresistive sensor and multi-channel robot arm developed. It reflects Oriental Medical Doctors' diagnostic processes, and its reproducibility test was done at Korea Institute of Oriental Medicine. We performed this study to set parameters diagnosing Sasang Constitution. 2. Methods One hundred thirty three subjects participated in this study. They are healty and approved this study. Before being tested with pulse analyzer, they had interview with Sasang Constitution Specialist to diagnose their Sasang Constitution. We established some useful parameters from parameters of pulse analyzer according to the Original Texts of Oriental Medicine and clinical experiences to analyze with clinical data of this study. 3. Results (I) There is a significant difference in pre-dicrotic notch time among all parameters of pulse analyzer in Sasang Constitution groups(P=0.047). (2) There is a significant difference in maximum pulse pressure in 33 to 48 year Sasang Constitution groups(P=0.010). (3) There is a significant difference in frequency width in 17 to 32 year Sasang Constitution groups(P=0.002). (4) There is a significant difference in CFS value in groups which OMD diagnoses; Floating & Sinking pulse(P=0.020). (5) There is a significant difference in pulse rate in groups which OMD diagnoses; Rapid & Slow pulse(P=0.000). (6) There is a significant difference in maximum pulse pressure in groups which OMD diagnoses; Deficient & Solid pulse(P=0.000). 4. Conclusions Analyzing parameters in each Sasang Constitution group, we found it shows significant difference in maximum pulse pressure and corresponding tendency in coefficient of floating & sinking pulse with theories of Sasang Consti-tutional Medicine. As we accumulate more clinical data, we will establish algorithm to diagnose Sasang Constitution using a pulse analyzer.

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Monteggia 골절의 임상적 고찰 (Clinical Study on Monteggia Fracture)

  • 서재성
    • Journal of Yeungnam Medical Science
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    • 제4권2호
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    • pp.131-138
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    • 1987
  • 1. 총 8예중 남자 6례, 여자 2례이었다. 2. 손상의 원인은 낙상이 4례로 가장 많았다. 3. Bado 분류에 의한 빈도는 I형이 4례(50%), II형 1예(12.5%), III형 3예(37.5%)이었다. 4. 척골골절의 위치는 상 1/3 이상 부위가 7예이었다. 5. 요골두 탈구 방향은 전방이 3예로가장 많았다. 6. 치료는 소아는 2예 모두 비수술적 방법으로 하였으며 성인 6예중 2예는 도수정복하고 4례는 골골절윤 압박금속판을 사용하여 내고정하였으며 골두 탈구는 모두 도수정복하였다. 7. 결과는 Bruce 등에 의한 판정으로 excellent 3예, good 2례, fair 1예, poor 2례이었다.

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Changes in Salivary Cortisol Concentration in Horses during Different Types of Exercise

  • Kang, Ok-Deuk;Lee, Wang-Shik
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권5호
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    • pp.747-752
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    • 2016
  • This study aimed to estimate the change of stress level in horses based on cortisol concentration levels in their saliva. A total of 61 horses were divided into the following three groups: i) tourist riding experience (TR, n = 23); ii) resting group (RR, n = 14); and iii) horse-riding education (ER, n = 24). The saliva samples of TR and ER groups were taken using plain cotton Salivettes four times a day: at 07:00 (basal), 11:00 (Exercise 1, after 1-hour exercise in the morning), 14:00 (Exercise 2, after 1-hour exercise in the afternoon), and 16:00 (Exercise 3, after 1-hour exercise in the afternoon). The saliva samples of RR were measured at the same time. The samples were analyzed using the SAS program general linear model procedure. In a percentage relative to the base value, cortisol levels in Exercise 3 were confirmed to decrease in all groups as compared to the basal value percentage in the following sequence: ER>TR>RR. The highest peak was confirmed in Exercise 2 (approximately 131%) of RR group and the lowest peak appeared in Exercise 3 (approximately 52%) of ER group. Therefore, resting without any particular exercise can also increase the stress level of horses. Thus, it is better to exercise, as exercise can reduce the stress level, even in cases when riders are clumsy or lack appropriate horse-riding experience. The results of the present study are useful to equestrian center owners and educational riding instructors in that they provide a meaningful insight into a better horse management.

부양부담과 가족극복력이 치매노인 부양가족의 적응에 미치는 영향 (Effects of Burden and Family Resilience on the Family Adaptation of Family Caregivers of Elderly with Dementia)

  • 장혜영;이명선
    • 성인간호학회지
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    • 제25권6호
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    • pp.725-735
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    • 2013
  • Purpose: The purpose of this study was to investigate the levels of burden, family resilience and adaptation of caregivers of elderly patients with dementia, and further to identify factors influencing their adaptation. Methods: A cross-sectional descriptive study was designed. Data were collected from questionnaires distributed to 131 family caregivers of elderly patients who visited at the Centers for Dementia in Seoul during 2012~2013. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation analysis, and stepwise multiple regression. Results: The average age of the care giving subjects was 63.58, and 31.3% were male, and 41.2% were the spouses. Statistically significant relationships were found between burden and adaptation (r=-.38, p<.001), and between family resilience and adaptation (r=.52, p<.001), and between burden and family resilience (r=-.35, p=.001). Thirty percent of adaptation was explained by burden and family resilience. The most influencing factor to adaptation was family resilience which explained about 27% of the variance. Conclusion: The results of the study clearly indicate that family resilience explains better than burden on adaptation of family caregivers. Thus, to develop more effective nursing intervention for family caregivers of elderly patients with dementia, it would be necessary to integrate family resilience in the programs. 27% is not that much and I wonder if we have to do more work to identify the factors that influence care giving.

수지 재건시 불충분한 혈행상태의 수혜부에 시행한 동맥화 정맥 유리 피판술 (Arterialized Venous Free Flap at the Insufficient Vascular Recipient Bed in Finger Reconstruction)

  • 이영근;박기태;이준모;박혁
    • Archives of Reconstructive Microsurgery
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    • 제21권2호
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    • pp.131-136
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    • 2012
  • Purpose: Arterialized venous flap is useful for reconstruction of the traumatic soft tissue defect in fingers, but insufficient circulation of the traumatic fingers makes surgeons annoying to use the flap. We have grafted flaps in 7 fingers with insufficient vascular bed hoping to expanded the category of the flap. Materials and Methods: Arterialized venous flap have transplanted in 7 fingers from March 2008 through February 2010 and followed up for 4 to 16 months(average 7.2 months). They were all male with a mean age at the time of surgery was 33. The main injury was crushing in 4 degloving, contact burn and saw injury was I respectively. Time interval from injury to flap transplantation was average 3.1. weeks(3 days to 6 weeks). Designed flap size ranges from $8cm{\times}3.5cm$to $4cm{\times}3cm$. Vessel type of flap was one artery with two veins were 5 cases and one artey with one vein 2. Flap type was cutaneous in 3, tendocutaneous 2, neurotendocutaneous 1 and neurocutaneous 1. The circulation state of recipient site was avascular in 2 cases, insufficiency 3 and tip avascular 2. Results: Arterialized venous flap was complete survived in 2 cases, partial necrosis(less than 10%) 3 and failed in 2. Conclusion: An arterialized venous free flap could be a useful procedure for reconstruction in soft tissue or combined defect of the finger despite an avascular or insufficient vascular beds if the recipient beds were free from infection.

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Interpretation of Dispersion Phenomena in Grunwald-Winstein Correlation for Solvolyses of Naphthoyl Chloride

  • Ryu, Zoon-Ha;Ju, Chang-Suk;Sung, Dae-Dong;Sung, Nak-Chang;Bentley, T. William
    • Bulletin of the Korean Chemical Society
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    • 제23권1호
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    • pp.123-131
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    • 2002
  • Solvolyses rate constant of 1- and 2- naphthoyl chlorides (1 and 2) are reported for aqueous binary mixtures with methanol, ethanol, fluorinated alcohol, acetonitrile and dioxane. Kinetic solvent isotope effects (KISE) in methanol and product selectivities (S) of 2-naphthoyl chloride (2) in alcohol-water are also reported. Dispersions in Grunwald-Winstein correlations $(r{\leq}0.901)$ are discussed by multiple regression analysis incorporating ionizing power $(Y_{Cl})$ scale and rate-rate profiles. Major causes for these phenomena are investigated as an aromatic ring solvation effects, in conjunction with weakly nucleophilic solvation effects ($S_N2$ character), for solvolyses of 1 and for solvolyses of 2, as dual reaction channels, described as $S_N1$-$S_N2$ and $S_AN$-$S_N2$ processes. Distinct border lines between the two pathways are derived from solvolyses rates of 2 in 18 solvent using the results of $log(k/k_o)=mY_{Cl}+lN_T+hI$ plot with values of 1.13 for m, 0.37 for l and 0.15 for h value in 5 aqueous fluorinated alcohol mixtures. Using rate-product correlation, the validity of a third order model based on a general base catalyzed by solvent and contribution from these rate constants, $k_{aa},\;k_{aw}$ and $k_{aw}$, are investigated for $S_AN$-$S_N2$ solvolyses of 2 favored in more rich alcohol media and gradual addition of water to alcohol solvent shows a great shift away from stoichiometric solvation to predominantly medium effects. Rate-rate correlation between solvolyses of 2 and trimethyl acetylchloride (5) with alkyl group in the 29 aqueous solvent mixtures shows appreciable linearity (slope = 0.84, r = 0.987), caused by the same pathway ($S_N1$-$S_N2$ process), even if this correlation coincides with appreciable dispersion (different solvation effect).

상류 전통주거 거창(居昌) 동계(桐溪) 정온(鄭蘊) 종택의 공간과 생활의 복원을 통한 해석 (Interpretation of the Jeong-On's Mansion, Traditional Upper Class House, in Geochang Focused on Dweller's Life)

  • 박희영;이희봉
    • 건축역사연구
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    • 제12권3호
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    • pp.131-148
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    • 2003
  • This study has main purpose to understand the traditional house, not by outside researcher's but by inside dweller's view. The house in Geochang, is descendent house of Jeong-On who was faithful scholar at Chosen Dynasty. In order to understand, I restore firstly the house form and space at traditional era, 60 years ago, and every dwellers not only family members but also servants and guests, by interviewing old matriarch. One of the main rules of the house disposition is Ancester worshipping life. Worshipping floor of Anchae, main building, is located unusually in front of Shrine for Jeong-On, in order to connect all activities directly. Sarangchae, men's building, opened to the funeral mourners, is separated by a wall because women have to serve foods and wail at the backside. Space for everyday life is separated by man/woman, insider/outsider, master/subordinate. Agricultural production is also key factor of the space allocation: big storage buildings for rice crop needed to tenant farming. Both activities of ancestor worship ceremony and guest greeting need large kitchen annex area for food preparation and serving space of rear veranda floor. A number of guests visit the house: guest-greeting activity is taken place from the family pavilion, Neungheo-Jeong and Saranchae by the social position. This study show that architectural space and form of the house reflects exactly dwellers life.

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Assessment of Microbial and Radioactive Contaminations in Korean Cold Duck Meats and Electron-Beam Application for Quality Improvement

  • An, Kyung-A;Jo, Yunhee;Arshad, Muhammad Sajid;Kim, Gui-Ran;Jo, Cheorun;Kwon, Joong-Ho
    • 한국축산식품학회지
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    • 제37권2호
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    • pp.297-304
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    • 2017
  • Animal-origin food products pose serious threat to public food safety due to high microbial loads. The microbial and radioactive contaminations in commercial cold duck meat products were evaluated. Ten different lots of commercial samples ($C_1-C_{10}$) were classified based on type and smoking process. All samples were highly contaminated (< 4-7 Log CFU/g) with total aerobic bacteria (TAB), yeasts and molds (Y&M), and 7 samples ($C_1-C_7$) were positive for coliforms. Furthermore, three samples were contaminated with Listeria monocytogenes ($C_4-C_6$) and one with Salmonella typhimurium ($C_6$). No radionuclides ($^{131}I$, $^{137}Cs$, and $^{134}Cs$) were detected in any sample. The results of DEFT (direct epifluorescent filter technique)/APC (aerobic plate count), employed to screen pre-pasteurization treatments of products, indicated that smoked samples were positive showing DEFT/APC ratios higher than 4. Notably, the samples showed a serious threat to microbial safety, thus were irradiated with electron-beam (e-beam). The $D_{10}$ values for S. typhimurium and L. monocytogenes were 0.65 and 0.42 kGy, respectively. E-beam application at 3 and 7 kGy resulted in reduction of initial TAB, Y&M, and coliform populations by 3 and 6 log cycles, respectively. Thus, e-beam was proven to be a good decontamination approach to improve the hygiene of cold duck meat.