• 제목/요약/키워드: ${\omega}-3$

검색결과 2,914건 처리시간 0.029초

The effects of the DASH diet education program with omega-3 fatty acid supplementation on metabolic syndrome parameters in elderly women with abdominal obesity

  • Choi, Seung-Hye;Choi-Kwon, Smi
    • Nutrition Research and Practice
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    • 제9권2호
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    • pp.150-157
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    • 2015
  • BACKGROUND/OBJECTIVES: The purpose of this study was to investigate the overall effects of a tailored Dietary Approaches to Stop Hypertension (DASH) nutritional intervention program which included omega-3 fatty acids supplementation, on dietary self-efficacy, dietary knowledge, and dietary behaviors in Korean elderly women with abdominal obesity. Furthermore, we investigated the effects of the program on metabolic syndrome parameters including the antioxidant capacities in these subjects. SUBJECTS/METHODS: A randomized, controlled trial was conducted for 8 weeks. The experimental group (n = 21) received a weekly tailored nutritional program for 8 weeks and the control group (n = 18) received only one educational session. The clinical survey was conducted before and after the intervention period. RESULTS: After the intervention, dietary self-efficacy (P = 0.023), frequency of fruit intake (P = 0.019), and dietary fiber intake (P = 0.044) were higher in the experimental group than in the control group. The oxidative stress (P < 0.001) was lower in the experimental group than in the control group. Moreover, low density lipoprotein (LDL) cholesterol (P = 0.023) had significantly decreased in the experimental group but not in the control group after the intervention. CONCLUSIONS: The intervention program including omega-3 fatty acid supplementation had a positive effect on dietary self-efficacy, dietary behaviors, and oxidative stress among aged women with abdominal obesity.

2차원과 3차원 아음속 공동 유동 특성에 대한 수치적 연구 (NUMERICAL ANALYSIS OF TWO- AND THREE-DIMENSIONAL SUBSONIC TURBULENT CAVITY FLOWS)

  • 최홍일;김재수
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2007년도 추계 학술대회논문집
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    • pp.187-193
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    • 2007
  • The flight vehicles have cavities such as wheel wells and bomb bays. The flow around a cavity is characterized as unsteady flow because of the formation and dissipation of vortices due to the interaction between the freestream shear layer and cavity internal flow, the generation of shock and expansion waves. Resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, numerical analysis was performed for cavity flows by the unsteady compressible three dimensional Reynolds-Averaged Navier-Stokes (RANS) equations with Wilcox's ${\kappa}\;-\;{\omega}$ turbulence model. The cavity has the aspect ratios of 2.5, 3.5 and 4.5 for two-dimensional case, same aspect ratios with the W/D ratio of 2 for three-dimensional case. The Mach and Reynolds numbers are 0.53 and 1,600,000 respectively. The flow field is observed to oscillate in the "shear layer mode" with a feedback mechanism. Based on the SPL(Sound Pressure Level) analysis of the pressure variation at the cavity trailing edge, the dominant frequency was analyzed and compared with the results of Rossiter's formula. The MPI(Message Passing Interface) parallelized code was used for calculations by PC-cluster.

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3차원 공동의 폭변화에 따른 초음속 유동에 대한 수치분석연구 (NUMERICAL ANALYSIS OF THREE DIMENSIONAL SUPERSONIC CAVITY FLOW FOR THE VARIATION OF CAVITY SPANWISE RATIO)

  • 우철훈;김재수;최홍일
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2006년도 추계 학술대회논문집
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    • pp.181-184
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    • 2006
  • High-speed flight vehicle have various cavities. The supersonic cavity flow is complicated due to vortices, flow separation and reattachment, shock and expansion waves. The general cavity flow phenomena include the formation and dissipation of vortices, which induce oscillation and noise. The oscillation and noise greatly affect flow control, chemical reaction, and heat transfer processes. The supersonic cavity' flow with high Reynolds number is characterized by the pressure oscillation due to turbulent shear layer, cavity geometry, and resonance phenomenon based on external flow conditions, The resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, we performed numerical analysis of cavities by applying the unsteady, compressible three dimensional Reynolds-Averaged Navier-Stokes(RANS) equations with the ${\kappa}-{\omega}$ turbulence model. The cavity model used for numerical calculation had a depth(D) of 15mm cavity aspect ratio(L/D) of 3, width to spanwise ratio(W/D) of 1.0 to 5.0. Based on the PSD(Power Spectral Density) and CSD(Cross Spectral Density) analysis of the pressure variation, the dominant frequency was analyized and compared with the results of Rossiter's Eq.

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공동의 폭 변화에 따른 3차원 초음속 공동 유동연구 (NUMERICAL ANALYSIS OF THREE DIMENSIONAL SUPERSONIC CAVITY FLOW FOR THE VARIATION OF CAVITY SPANWISE RATIO)

  • 우철훈;김재수
    • 한국전산유체공학회지
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    • 제11권4호
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    • pp.62-66
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    • 2006
  • High-speed flight vehicle have various cavities. The supersonic cavity flow is complicated due to vortices, flow separation, reattachment, shock waves and expansion waves. The general cavity flow phenomena includes the formation and dissipation of vortices, which induce oscillation and noise. The oscillation and noise greatly affect flow control, chemical reaction, and heat transfer processes. The supersonic cavity flow with high Reynolds number is characterized by the pressure oscillation due to turbulent shear layer, cavity geometry, and resonance phenomenon based on external flow conditions. The resonance phenomena can damage the structures around the cavity and negatively affect aerodynamic performance and stability. In the present study, we performed numerical analysis of cavities by applying the unsteady, compressible three dimensional Reynolds-Averaged Navier-Stokes(RANS) equations with the ${\kappa}-{\omega}$ turbulence model. The cavity model used for numerical calculation had a depth(D) of 15mm cavity aspect ratio (L/D) of 3, width to spanwise ratio(W/D) of 1.0 to 5.0. Based on the PSD(Power Spectral Density) and CSD(Cross Spectral Density) analysis of the pressure variation, the dominant frequency was analyzed and compared with the results of Rossiter's Eq.

해수오염 된 CSPE의 물리·전기적 상태감시에 관한 연구 (A Study on Physical and Electrical Condition Monitoring of Seawater Soaked CSPE)

  • 신용덕;이정우;전황현;김인용
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2015년도 제46회 하계학술대회
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    • pp.1136-1137
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    • 2015
  • The accelerated thermal aging of chlorosulfonated polyethylene (CSPE) was performed for 0 days, 80.82 days, and 161.63 days at $100^{\circ}C$, which is equivalent to 0y, 40y, and 80y of aging, respectively, at $50^{\circ}C$. The volume electrical resistivity of dried CSPE for 570~630 days after seawater and freshwater soaking, are $1.109{\times}10^{14}{\Omega}{\cdot}cm$, $8.546{\times}10^{13}{\Omega}{\cdot}cm$ and $8.466{\times}10^{13}{\Omega}{\cdot}cm$. The applied voltage rising time of 11~12 second and dielectric breakdown time of 9~11 second of the accelerated thermal aged CSPE is shorter than those of 12~13 and 11~13 second of the non-accelerated thermal aged CSPE, respectively. It is shown that oxidation, fragment and crack are formated at hole of dielectric breakdown in CSPE. The apparent density of dried CSPE for 750 days are $1.555g/cm^3$, $1.595g/cm^3$$1.597g/cm^3$ according to accelerated thermal aging year, respectively.

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들깨유 섭취가 흰쥐의 출혈시간, 트롬복산 생성 및 혈소판의 지방산 조성에 미치는 영향 (Effects of Perilla Oil Intake on Bleeding Time, Thromboxane Formation and Platelet Fatty Acid in Rats)

  • 한용남;윤혜원;김숙희;한병훈
    • 생약학회지
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    • 제18권1호
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    • pp.5-13
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    • 1987
  • Male rats were fed diets containing perilla oil, sardine oil or corn oil for 15 weeks in order to investigate their antithrombotic effects. Rats given perilla oil and sardine oil diets showed significantly longer bleeding time, and lower level of malondialdehyde generation during thrombin-induced aggregation of platelets than rats given corn oil. With regard to the composition of platelet fatty acid, the ratio of eicosapentaenoic acid(EPA) $(20:5{\omega}3)$ to arachidonic acid $(20:4{\omega}6)$ of perilla oil, sardine oil and corn oil treated rats were 0.54, 0.96 and 0.01, respectively, suggesting that linolenic acid $(18:3{\omega}3)$ of perilla oil was metabolized to EPA which is known to have antithrombotic activity.

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Intestinal Hypoganglionosis Leading to Intestinal Failure and the Compassionate Use of OmegavenTM

  • Khalaf, Racha;Karjoo, Sara;Danielson, Paul;Wilsey, Michael;Shakeel, Fauzia
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제20권1호
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    • pp.55-60
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    • 2017
  • Intestinal hypoganglionosis is a rare innervation disorder that provides numerous nutritional, medical and surgical challenges. In this case report, we present a case of a newborn with intestinal hypoganglionosis leading to intestinal failure and intestinal failure-associated liver disease who responded to $Omegaven^{TM}$, a fat emulsion comprised of omega-3 fatty acids. $Omegaven^{TM}$ has been shown to be beneficial in the management of cholestatic liver injury. Clinical success with $Omegaven^{TM}$ was seen in this patient with a clear decrease in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and complete resolution of cholestasis with a direct bilirubin of zero within two weeks of initiation of $Omegaven^{TM}$. No current guidelines for the diagnosis and management of hypoganglionosis are available. We recommend a multidisciplinary approach and the use of novel therapies such as fat emulsions composed of omega-3 fatty acids for improved patient outcomes. Appropriate compassionate use protocols should be obtained from the Food and Drug Administration prior to initiation of $Omegaven^{TM}$.

Synthesis of 5-Chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2(4-methoxyphenyl)benzofuran as a $\beta-Amyloid$ Aggregation

  • Choi, Hong-Dae;Seo, Pil-Ja;Son, Byeong-Wha;Kang, Byoung-Won
    • Archives of Pharmacal Research
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    • 제26권12호
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    • pp.985-989
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    • 2003
  • An efficient synthesis of 5-chloro-3-[4-(3-diethylaminopropoxy)benzoyl]-2-(4-methoxyphenyl)benzofuran (8), a potent $\beta$-amyloid aggregation inhibitor, is described. 5-Chloro-2-(4-methoxyphenyl)benzofuran (3) was obtained by the one-pot synthesis of 4-chlorophenol with $\omega$(methylsulfinyl)-p-methoxyacetophenone (1) under Pummerer reaction conditions, and it was followed by the desulfurization of the resultant 5-chloro-3-methylthio-2-(4-methoxyphenyl)benzofuran (2e). Acylation of benzofuran 3 with 4-(3-bromopropoxy)benzoyl chloride (6) gave the ketone 7, which was converted into compound 8 by the treatment of diethylamine.

HWE에 의하여 성장된 CdS : In 박막의 전기광학적 특성과 그 응용 (Electro-Optical Characteristics of CdS : In Films Grown by Hot-Wall Evaporation and Its Application)

  • 최용대;윤희중;김진배;이완호;신영진;양동익
    • 한국진공학회지
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    • 제1권3호
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    • pp.360-370
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    • 1992
  • HWE(Hot-Wall Epitaxy) 방법에 의하여 pyrex 유리기판 위에 CdS 다결정 박막을 성장하였다. X-선 회절실험 결과 CdS 박막은 육방정이었는데 (0002)면보다 91013)면이 강 하게 성장됨을 알 수 있었다. 전자현미경으로 표면을 분석한 결과 입자의 크기는 기판의 온 도가 48$0^{\circ}C$, 증발원의 온도가 $610^{\circ}C$일 때 1~1.5$mu extrm{m}$로서 가장 컸다. 박막의 표면저항은 4-point probe로서 측정한 결과 10-8$\Omega$/\ulcorner이상이었다. 성장된 CdS 다결정 박막의 photoluminesence을 20K에서 측정하였는데 bound exciton, donor acceptor pair에 의한 발광이 관측되었다. Spectral response의 peak는 505nm이었다. CdS 다결정 박막의 표면 저항을 줄이기 위하여 여러 가지 온도에서 Indium을 확산시켰다. 그 결과 표면저항은 ~ $\times$ 101에서 ~ $\times$ 103$\Omega$/\ulcorner 정도 감소되었다. 50$0^{\circ}C$에 In을 1시간 확산시켰을 때 표면저항은 1300$\Omega$/\ulcorner이었다. 이 때 CdS : In의 운반자 농도는 1.2 $\times$ 1018cm-3, 이동도는 1.8cm-2/V-sec, 비저항은 1.3 $\times$ 10-2$\Omega$-cm이었다. CdS : In의 photoluminescence는 20K 에서 Gaussian curve를 보여 주었으며 peak의 위치는 510nm이었다. CdS : In 박막의 spectral response의 peak는 상온에서 500nm이다. CdS : In 광전도 cell의 sensitivity ${\gamma}$ =0.77이고, 최대 허용소비전력은 p=120mW, 100lux에서 rise time은 8 msec, decay time 은 6 msec이다.

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잉크젯 프린팅된 Cu 박막의 응력해소를 통한 전기적 특성 개선 (The Improvement of Electrical Characteristics of Inkjet-printed Cu films with Stress Relaxation during Thermal Treatment)

  • 이설민;주영창
    • 마이크로전자및패키징학회지
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    • 제21권4호
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    • pp.57-62
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    • 2014
  • 미래형 유연소자 개발 시 비용감소 및 공정적합성 개선을 위해 동박을 잉크젯 프린팅법을 이용해 공중합체 유연기판 상 형성하고, 전기적 특성에 열처리 분위기가 미치는 영향을 확인하기 위해 3 종류의 환원분위기에서 열처리를 진행하여 보았다. 그 결과 200도의 낮은 온도에서 환원 특성이 뛰어난 포름산 분위기에서 전도체 수준의 비저항은 얻을 수 있었으나, 열처리 시 발생하는 응력으로 인해 발생된 표면균열에 기인해 그 값이 기존 동박에 비해 매우 높았다. 이에 비정질재료에서 응용되는 응력해소법을 응용하여 표면균열을 억제한 결과 230도 열처리 시 기존 열처리 방법에서는 $7.4{\mu}{\Omega}cm$의 비저항을 보이나, 응력해소를 통한 표면 균열이 억제된 시편에서는 $3.4{\mu}{\Omega}cm$의 비저항 값을 얻을 수 있었다. 특히 등온열처리에 의한 응력해소 효과를 확인하기 위해 동일 온도에서 등온시간 없이 열처리를 진행한 결과, 표면균열이 억제되지 못함을 확인할 수 있었다.