• Journal of the Korean Data and Information Science Society
• /
• 제9권2호
• /
• pp.311-322
• /
• 1998

본 논문에서는 환자의 수명과 치료횟수의 모형화를 위해 관측가능한 공변량을 포함하는 동시에 치료횟수에 대해 관측불가능한 환경요인을 고려하기 위한 주변환경효과모형을 이용하고자 한다. 환경 효과를 나타내는 분포를 감마분포로 가정 하여 사망시간과 치료횟수의 결합모형을 개발하고, 모형에 포함된 모수의 추론과정을 논의하며, 개발된 모형을 Autologous Blood and Marrow Transplant Registry(ABMTR)에 등록된 환자의 자료에 적용하여 환경효과를 고려하지 않은 독립모형과 비교하여 치료횟수에 영향을 미치는 환경요인의 효과를 검토하고자 한다.

• 한국식품과학회지
• /
• 제20권1호
• /
• pp.59-62
• /
• 1988

일반계 및 다수계 쌀 각 6품종을 대상으로 뜨거운 밥($70^{\circ}C$)과 식은 밥($20^{\circ}C$)의 텍스쳐를 평가하고 쌀 및 전분의 성질과의 상호 관계를 조사 하였다. 일반계와 다수계 밥의 텍스쳐는 유의적인 차이를 보이지 않았다. 밥의 단단함은 식은 밥에서 set-back과 정의상관(${\gamma}$=0.613)관계를 나타내었으며, 쌀의 아밀로스 함량은 밥의 단단함과는 뚜렷한 상관 관계를 보이지 않았다.

• Journal of Microbiology and Biotechnology
• /
• 제10권4호
• /
• pp.535-538
• /
• 2000

Streptomyces lavendulae FRI-5 produces the ${\gamma}$-butyrolactone autoregulator IM-2, which is required for nucleoside antibiotic producetion. We have developed a system for introducing DNA into S. lavendule FRI-5 via conjugal transfer from Esherichia cole. Conditions were established for conjugation of the oriT-and attP-containing plasmid pSET152 from E. coli ET12567 (pUZ8002) to FRI-5. Conjugation resulted in integration of the plasmid at the chromosomal C31 attB site. The frequency of intergeneric conjugation varied with the medium used. The highest frequency ($1.6\times10-5$ per recipient) was obtained on ISP medium 2 containing 10mM MgCl2. Southern blot and phenotypic analyses of exconjugants revealed that S. lavendulae FRI-5 contains a unique C31 attB site, and that integration of heterologous DNA into the attB site did not interfere with morphological differentiation or IM-2-dependent signal transduction, including the production of a blue pigment. This system will now enable detailed genetic analysis of the regulation of antibiotic production in S. lavendulae FRI-5.

• 융합보안논문지
• /
• 제6권3호
• /
• pp.145-153
• /
• 2006

본 논문에서는 기록값 통계량을 이용한 무한 고장 NHPP 모형들이 제안되었다. 이 모형들은 결함당 고장 발생률이 단조 증가하거나 단조 감소하는 패턴을 가진다. 그리고 수명 분포에서는 어랑 분포, 랄리 분포와 굼벨를 이용한 소프트웨어 신뢰성 모형을 적용하여 비교연구에 초점을 두었다. 고장 간격 시간 자료를 이용한 무한 고장 NHPP 모형들에 대한 모수 추정법은 최우 추정법을 사용하였고 적용 분포들의 적용을 용이하게 하기 위하여 특수한 형태를 제시하였다. 고장 자료의 분석을 위하여 산술 및 라플라스 추세 검정과 적합도 및 치우침 검정을 실시하여 그 결과를 나열하였다.

• Journal of Radiation Protection and Research
• /
• 제26권3호
• /
• pp.203-206
• /
• 2001

The mathematical processing (unfolding) of pulse height spectra from a scintillation detector helps to calculate the photon fluence rate energy distribution in a measured photon field. The data processing is based on the knowledge of detection system response function and directional dependence respectively. The experimental results of the photon fields measurements in the vicinity of the spent fuel temporary storage and inside the storage hall are presented. The containers Castor 440 are used for temporary storing of the burnt up fuel assemblies in the Czech nuclear power plant Dukovany. A set of periodical measurements was performed in order to get basic information on the time dependence of the photon fields spatial distributions and spectral characteristics in the temporary storage hall and its vicinity. The photon fields were measured by the scintillation system. The obtained photon fields spatial distributions and spectral characteristics present the information on the radiation hazard in the storage.

• Nuclear Engineering and Technology
• /
• 제31권4호
• /
• pp.423-431
• /
• 1999

A radiotracer technique has been developed to monitor the rotational movement of two piston rings in one cylinder during engine operation. The rings were labeled with two different kinds of radioisotopes, i.e. $^{60}$ Co and $^{192}$ Ir, for identification of the top ring from the second ring. The radiotracers were implanted in a small hole bored on the inner side of each piston ring. The rings were installed in a single cylinder hydrogen engine and three Nal scintillation detectors were mounted around the engine block to measure the gamma radiation. The angle of ring-gap orientation was determined from the radiation counts measured with the three detectors during engine operation. Two windows (upper window for $^{60}$ Co and lower window for $^{192}$ Ir) were set on each ratemeter to count radiation from the two isotopes separately. Procedure to convert the radiation counts to the position of the ring gap was established. With the software programmed with MS-Visualbasic, radiation counts were compared with the reference responses that were measured at angular intervals of 10$^{\circ}$for each piston ring in advance of the experiment. The result was used for the evaluation of the relationship between the orientation of ring-gaps and oil consumption. It was found that an increase in the oil consumption rate of a specific operation condition was closely related to the relative phase angle of the two piston rings.

• JSTS:Journal of Semiconductor Technology and Science
• /
• 제15권6호
• /
• pp.601-607
• /
• 2015

A set of novel silicon controlled rectifier (SCR) devices' characteristics have been analyzed and verified under the electrostatic discharge (ESD) stress. A ring-shaped diffusion was added to their anode or cathode in order to improve the holding voltage (Vh) of SCR structure by creating new current discharging path and decreasing the emitter injection efficiency (${\gamma}$) of parasitic Bipolar Junction Transistor (BJT). ESD current density distribution imitated by 2-dimensional (2D) TCAD simulation demonstrated that an additional current path exists in the proposed SCR. All the related devices were investigated and characterized based on transmission line pulse (TLP) test system in a standard $0.5-{\mu}m$ 24 V CDMOS process. The proposed SCR devices with ring-shaped anode (RASCR) and ring-shaped cathode (RCSCR) own higher Vh than that of Simple SCR (S_SCR). Especially, the Vh of RCSCR has been raised above 33 V. What's more, their holding current is kept over 800 mA, which makes it possible to design power clamp with SCR structure for on chip ESD protection and keep the protected chip away from latch-up risk.

• Journal of Advanced Marine Engineering and Technology
• /
• 제40권2호
• /
• pp.131-137
• /
• 2016

In reliability analysis, it is quite common for the failure of any individual or item to be attributable to more than one cause. Moreover, observed data are often censored. Recently, progressive hybrid censoring schemes have become quite popular in life-testing problems and reliability analysis. However, a limitation of the progressive hybrid censoring scheme is that it cannot be applied when few failures occur before time T. Therefore, generalized progressive hybrid censoring schemes have been introduced. In this article, we derive the likelihood inference of the unknown parameters under the assumptions that the lifetime distributions of different causes are independent and exponentially distributed. We obtain the maximum likelihood estimators of the unknown parameters in exact forms. Asymptotic confidence intervals are also proposed. Bayes estimates and credible intervals of the unknown parameters are obtained under the assumption of gamma priors on the unknown parameters. Different methods are compared using Monte Carlo simulations. One real data set is analyzed for illustrative purposes.

• Bioinformatics and Biosystems
• /
• 제2권1호
• /
• pp.28-32
• /
• 2007

The protein phosphorylation is one of the important processes in the cell signaling pathway. A variety of protein kinase families are involved in this process, and each kinase family phosphorylates different kinds of substrate proteins. Many methods to predict the kinase-specific phosphoryrated sites or different types of phosphorylated residues (Serine/Threonine or Tyrosin) have been developed. We employed Supprot Vector Machine (SVM) to attempt the prediction of protein kinase specific phosphorylation sites. 10 different kinds of protein kinase families (PKA, PKC, CK2, CDK, CaM-KII, PKB, MAPK, EGFR) were considered in this study. We defined 9 residues around a phosphorylated residue as a deterministic instance from which protein kinases determine whether they act on. The subsets of PSI-BALST profile was converted to the numerical vectors to represent positive or negative instances. When SVM training, We took advantage of multiple SVMs because of the unbalanced training sets. Representative negative instances were drawn multiple times, and generated new traing sets with the same positive instances in the original traing set. When testing, the final decisions were made by the votes of those multiple SVMs. Generally, RBF kernel was used for the SVMs, and several parameters such as gamma and cost factor were tested. Our approach achieved more than 90% specificity throughout the protein kinase families, while the sensitivities recorded 60% on average.

• Progress in Superconductivity
• /
• 제9권2호
• /
• pp.140-145
• /
• 2008

We report on the Josephson vortex dynamics in $Bi_2Sr_2CaCuO_{8+\delta}$ natural Josephson junctions by c-axis tunneling measurements. Beside the quasiparticle branches in the current-voltage characteristics, a new set of multiple branches, referred to as Josephson-vortex-flow branches (JVFBs), are observed. The JVFBs emerge in an in-plane magnetic field above $H_0\;=\;{\Phi}_0/{\gamma}s^2$ and show highly hysteretic behavior, which can be explained in terms of the recently proposed dynamic-phase-separation model. In this work we examined the effect on the JVFBs by the presence of pancake vortices generated as the external magnetic field was applied slightly tilted from the in-plane direction. JVFBs were found to become larger and prominent with increasing pancake vortex density as the tilt angle increased, which were presumably caused by slowing down of a Josephson vortex lattice in the presence of pancake vortices.