• Title/Summary/Keyword: ${\beta}-sitosterol{\

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A Study on the Chemical Components from the Roots of Dystaenia takeshimana (섬바디 뿌리의 성분 연구(II))

  • Kim, Beom-Hae;Kwon, Yong-Soo;Kim, Chang- Min
    • Korean Journal of Pharmacognosy
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    • v.24 no.4
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    • pp.296-298
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    • 1993
  • From the benzene soluble and butanol soluble portions of Dystaenia takeshimana Kitagawa which is indigenous to Korea, umbelliferone, skimmin, isoscopoletin, ${\beta}-sitosterol$, campesterol and stigmasterol have been isolated and identified on the basis of spectral data.

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Studies on the Components of Korean Ginseng(I) -On the Composition of Ginseng Sterols- (한국산(韓國産) 인삼(人參)의 성분에 관한 연구(I) -인삼 Sterol의 구성 성분에 대하여-)

  • Chung, Bo-Sup
    • Korean Journal of Pharmacognosy
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    • v.5 no.3
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    • pp.173-177
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    • 1974
  • Sterols were obtained from the non-saponifiable matters of ethereal and methanolic extracts of the root of Panax ginseng. The composition of sterols has been determined by gas chromatographic analysis. It was noted that campesterol, stigmastrol and ${\beta}-sitosterol$ were the major sterols in the ginseng. The results showed that contents of sterols were campesterol, $4.01{\sim}5.82%,\;stigmasterol,\;18.32{\sim}19.12%\;{\beta}-sitosterol,\;and\;75.11{\sim}77.74%$.

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Phytochemical Constituents from Cacalia koraiensis Nakai (참나래박쥐나물의 식물화학적 성분)

  • 이성옥;최상진;양민철;정애경;남정환;이규하;이종순;이강노
    • YAKHAK HOEJI
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    • v.47 no.1
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    • pp.10-13
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    • 2003
  • The phytochemical study of Cacalia koraiensis Nakai (Compositae) led to the isolation of eight compounds, $\beta$-sitosterol (1), stigmasterol (2), phytol (3), $\beta$-sitosterol-3-Ο-glucopyranoside (4), adenostylol (5), campesterol (6), germacradien-4$\alpha$-ol (7), and quercetin-3-rhamnoside (8). Their structures were established by chemical and spectroscopic methods. The cytotoxicity of the isolated compounds was evaluated by SRB assay against five cultured human tumor cell lines.

Isolation and Identification of Lipids from the Fruits of Acanthopanax sessiliflorus (오가피(Acanthopanax sessiliflorus Seeman) 열매로부터 지질 화합물의 분리 및 동정)

  • Kim, Su-Yeon;Lee, Dae-Young;Seo, Kyeong-Hwa;Rho, Young-Deok;Kim, Gye-Won;Cheoi, Dae-Sung;Baek, Nam-In
    • Journal of Applied Biological Chemistry
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    • v.55 no.2
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    • pp.103-107
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    • 2012
  • Acanthopanax sessiliflorus Seeman fruits (Araliaceae) were extracted at room temperature with 70% aqueous ethanol (EtOH). The concentrated extract was partitioned with ethyl acetate (EtOAc), n-butyl alcohol, and $H_2O$, successively. From the EtOAc fraction, four compounds were isolated through the repeated silica gel and octadecyl silica gel (ODS) column chromatographies. According to the results of physico-chemical and spectroscopic data including NMR, IR, and gas chromatography/mass spectrometer, the chemical structures of the compounds were determined as stigmasterol (1), linoleic acid (2), ${\beta}$-sitosterol (3), and stigmast-5-en-$3{\beta}$,$7{\beta}$-diol (4).

Chemical Constituents of the Aerial Parts of Chloranthus japonicus Sieb.

  • Heo, Jung-Eun;Jin, Jing Ling;Lee, Yong-Yook;YunChoi, Hye-Sook
    • Natural Product Sciences
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    • v.11 no.1
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    • pp.41-44
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    • 2005
  • Chemical investigation of the aerial parts of Chloranthus japonicus Sieb. led to the isolation a new compound, 9-hydroxy heterogorgiolide (1) and $isofraxidin-7-O-{\beta}-D-glucopyranoside$ (2), the isolation of which is reported for the first time from this plant, along with the known components, ${\beta}-sitosterol,\;{\beta}-sitosterol-3-O-{\beta}-D-glucopyranoside$, palmitic acid and octacosanoic acid. The structures of compound 1 and 2 were determined on the basis of spectroscopic data including two dimensional NMR and high resolution MS.

Phytochemical Constituents from Aconitum pseudolaeve Var. erectum (진범의 식물화학적 성분)

  • Kim, Dae-Keun;Kwak, Jong-Hwan;Song, Ki-Won;Kwon, Hack-Cheol;Zee, Ok-Pyo;Lee, Kang-Ro
    • Korean Journal of Pharmacognosy
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    • v.27 no.1
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    • pp.75-79
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    • 1996
  • Four steroids and one flavonol glycoside were isolated from the ethanol extract of the whole plant of Aconitum pseudolaeve var. erectum. Their structures were identified as ${\beta}-sitost-4-en-3-one$, 22-dihydro-stigmast-4-en-3,6-dione, ${\beta}-sitosterol$, ${\beta}-sitosterol-3-O-{\beta}-D-glucopyranoside$ and $kaempferol-3-O-{\beta}-D-glucopyranoside(astragalin)$ on the basis of spectral data.

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Studies on the Constituents of Oldenlandia diffusa (백화사설초(百花蛇舌草)의 성분(成分)에 관한 연구(硏究))

  • Kim, Young-Hee
    • Korean Journal of Medicinal Crop Science
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    • v.3 no.2
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    • pp.91-95
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    • 1995
  • From the whole plants of Oldenlandia diffusa ursolic acid together with sterols, ${\beta}-sitosterol$ and its $3-0-{\beta}-D-glucoside$ were isolated and characterized mainly by means of spectroscopic methods. Based on the present findings, it may be considered that this plant may contribute to be a rich source for ursolic acid.

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Constituents from the Non-Polar Fraction of Artemisia apiacea

  • Lee, Sanghyun;Kim, Kyoung-Soon;Shim, Sang-Hee;Park, You-Mie;Kim, Bak-Kwang
    • Archives of Pharmacal Research
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    • v.26 no.11
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    • pp.902-905
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    • 2003
  • Five compounds of terpenoids and coumarins were isolated from the non-polar fraction of Artemisia apiacea by open column chromatography. Their structures were elucidated as $\alpha$-amyrin (1), $\beta$-amyrin (2), $\beta$-sitosterol (3), 5,6,7-trimethoxycoumarin (4) and 6-methoxy-7,8-methylenedioxycoumarin (5) by chemical and spectroscopic analysis. This is the first report of the isolation of $\alpha$-amyrin, $\beta$-amyrin, 5,6,7-trimethoxycoumarin and 6-methoxy-7,8-methylene-dioxycoumarin from this plant.

Growth Inhibition of Toxic Cyanobacterium Microcystis aeruginosa, Using Rice Hull Methanolextracts (왕겨 메탄을 추출물을 이용한 독성 남조 Microcystis aeruginosa의 성장 억제)

  • Park, Myung-Hwan;Chung, Ill-Min;Kim, Baik-Ho;Hwang, Soon-Jin
    • Korean Journal of Ecology and Environment
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    • v.41 no.spc
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    • pp.99-106
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    • 2008
  • We examined the effects of crude and eight pure material (${\beta}$-sitosterol, ${\beta}$-sitosterol-${\beta}$-D-glucoside, 1-tetratriacontanol, hentriacontane, orizaterpenoid, stigmas-5-en-$3{\alpha}$ 26-diacetate, stearic acid, myristic acid), extracted from rice hull, on growth inhibition of toxic cyanobacterium, Microcystis aeruginosa NIER 10010. Strains of M. aeruginosa and Daphnia magna, obtained from the NIER (Korea) and BBE (Germany), were cultured in the CB medium with hard water. For all four treatment concentrations 0, 10, 100 and $1,000{\mu}g\;L^{-1}$) of the crude extract, the cell number of M. aeruginosa was reduced by $59{\sim}73%$ during the 7-day test period. Among eight kinds of pure extracts, ${\beta}$-sitosterol-${\beta}$-D-glucoside, hentriacontane and orizaterpenoid $(1,000{\mu}g\;L^{-1})$ exhibited relatively higher growth inhibition compared with other pure extracts. The mixture of three pure extracts (${\beta}$-sitosterol-${\beta}$-D-glucoside, hentriacontane and orizaterpenoid) showed the highest growth inhibition at $1,000{\mu}g\;L^{-1}$. Therefore, the synergistic effect was significantly highlighted by a mixture of the three pure extracts (p<0.05). Under the condition of $1,000{\mu}g\;L^{-1}$ in the crude extracts, D. magna exhibited survival rate by >85% for 96 hours. In conclusion, the growth inhibition of M. aeruginosa was probably attributed to the synergistic effect of various compounds extracted from the rice hull.