• Title/Summary/Keyword: ${\ast}$-component

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Effects of Azalea(Rhododendron mucronulatum) Pollen on the Carbon Tetrachloride Induced Hepatotoxicity in Mice (사염화탄소로 인한 간 독성에 미치는 진달래(Rhododendron mucronulatum)화분의 영향)

  • Yoon, Soo-Hong;Kang, Jeong-Hae;Kwon, Chong-Suk
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.18 no.4
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    • pp.363-370
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    • 1989
  • Nutritional value of azalea pollen and its effect on the carbontetrachloride induced liver damage were investigated in this experiment. Azalea pollen was primary composed of 58.96% of carbohydrate, 21.86% crude protein, 2.26% fat, and 2.89% ash. 17 amino acids and 22 fatty acids were quantitatively analyzed, and the major component of them was lysine, and linolenic acid, respectively. After administration of pollen and carbontetrachloride concomitantly. serum ALT, AST, LDH activities and tissue lipid peroxidation decreased significantly, but serum total lipid and cholesterol levels did not changed.

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Anti-hyperlipidemic Effect of the Isolated Component, Quercetin-3-O-rhamnoside and the Fractions from the Extract of Houttuynia Cordata in Mice (Poloxamer-407로 유도한 고지혈증 동물모델에서 Quercetin-3-O-rhamnoside 및 어성초 분획물의 항고지혈증 효과)

  • Kim, Do-Kuk;Kim, Se-Gun;Poudel, Amrit;Jeong, Tae-Suk;Jung, Hyun-Ju
    • Korean Journal of Pharmacognosy
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    • v.43 no.2
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    • pp.101-106
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    • 2012
  • The anti-hyperlipidemic effect of Houttuynia cordata was assessed in poloxamer-407 induced hyperlipidemic mice model. The butanol fraction and its isolated compound, quercetin-3-O-rhamnoside, significantly reduced the blood triglyceride and total-cholesterol level and increased the blood HDL-cholesterol level. They also showed the significant reductive effect on the blood AST and ALT level, rising in proportion to the liver damage, in hyperlipidemic mice.

Face Recognition by Using Principal Component Analysis of Unsupervised Learning (자율학습의 PCA를 이용한 얼굴인식)

  • Cho Yong-Hyun;Cha Joo-Hee
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.11a
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    • pp.583-586
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    • 2004
  • 본 논문에서는 자율학습의 속성을 가지는 주요성분분석을 이용한 얼굴인식 기법을 제안하였다. 이는 대용량의 입력 데이터를 통계적으로 독립인 특징들의 집합으로 변환시켜 중복신호를 제거하는 특성을 가지는 주요성분분석의 우수한 속성을 이용한 것이다. 제안된 기법을 Yale 얼굴영상 데이터베이스로부터 선택된 20개의 $320{\ast}243$ 픽셀의 영상을 대상으로 시뮬레이션한 결과, 주요성분의 개수에 따른 압축성능과 city-block, Euclidian, 그리고 negative angle(cosine)의 거리척도에 따른 인식에서의 분류성능에서 우수한 성능이 있음을 확인할 수 있었다.

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Preparation and characterization of fullerene dimer [C120] by trichloroperbenzoic acid oxidation method

  • Oh, Won-Chun;Jung, Ah-Reum;Ko, Weon-Bae
    • Analytical Science and Technology
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    • v.20 no.2
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    • pp.124-130
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    • 2007
  • In this study, we present the preparation and characterization of oxidized fullerene and fullerene dimer [$C_{120}$]. From the XRD data, other weak peaks with pristine fullerene [$C_{60}$] peaks were observed in the X-ray diffraction patterns for fullerene dimer [$C_{120}$]. SEM micrographs for the fullerene dimer [$C_{120}$] indicated that practically all the surface state was shown the drastic morphology changes and its outer surface is clearly visible and resulted in clogging and frost-like formation. From the MALDI-TOF mass spectra, the differences in the spectra recorded on two kinds of fullerene are due to the oxidation including chemical bonding and bridging between the $C_{60}$ molecules. We also obtained additional information from FT-IR spectra on functional component on the chemically modified surface of oxidized fullerene and fullerene dimer [$C_{120}$].

Evaluation of volatile organic compounds emitted from door-trim armrest using micro chamber and 20 L static chamber (마이크로 챔버와 20 L static chamber를 이용한 도어트림 암레스트로부터 방출되는 휘발성 유기화합물 평가)

  • Lee, Ik-Hee;Yoo, Ji-Ho;Kim, Man-Goo
    • Analytical Science and Technology
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    • v.24 no.4
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    • pp.290-297
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    • 2011
  • In present, evaluation method for car cabin air quality has been developed in ISO, China, Japan. Also The management standard for new produced car has been applied since 1, July, 2010. To manage car cabin air quality, It is important to evaluate VOC emitted from interior material. In this study, complete component of door trim armrest was evaluated in accordance with ISO 12219-5, cut component was evaluated in accordance with ISO 12219-3. The vapour gas was collected with stainless tube packed with Tenax TA and analyzed with TD-GC/MS. It was confirmed that emission rate of each compounds was difficult in each evaluation method. As a result, to evaluating each components composing door trim armrest, main sources of emitting VOCs in door trim armrest were PP substrate and adhesive.

Determination of mixing ratios in a mixture via non-negative independent component analysis using XRD spectrum (XRD 스펙트럼의 비음독립성분분석을 통한 혼합물 구성비 결정)

  • You, Hanmin;Jun, Chi-Hyuck;Lee, Hyeseon;Hong, Jae-Hwa
    • Analytical Science and Technology
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    • v.20 no.6
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    • pp.502-507
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    • 2007
  • X-ray diffraction method has been widely used for qualitative and quantitative analysis of a mixture of materials since every crystalline material gives a unique X-ray diffraction pattern independently of others, with the intensity of each pattern proportional to that material's concentration in a mixture. For determination of mixing ratios, extracting source spectra correctly is important and crucial. Based on the source spectra extracted, a regression model with non-negativity constraint is applied for determining mixing ratios. In some mixtures, however, X-ray diffraction spectrum has sharp and narrow peaks, which may result in partial negative source spectrum from independent component analysis. We propose several procedures of extracting non-negative source spectra and determining mixing ratios. The proposed method is validated with experimental data on powder mixtures.

Preventive effects of Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol (인진호탕(茵蔯蒿湯)과 한인진호탕(韓茵蔯蒿湯)이 알코올 투여(投與)로 유발(誘發)된 흰쥐의 고지혈증(高脂血症)과 간(肝) 손상(損傷)의 예방(豫防)에 미치는 영향(影響))

  • Kim, You-Chang;Kim, Seong-Mo;Park, Ji-Ha;Seo, Bu-Il;Choi, Hong-Sik
    • The Korea Journal of Herbology
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    • v.21 no.3
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    • pp.47-54
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    • 2006
  • Objectives : This study was performed to compare the preventive effect of water extracts from Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Injinho-tang and Haninjinho-tang on hyperlipidemia induced by alcohol. Injinho-tang group showed significant decrease of triglyceride, body weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of total cholesterol, triglyceride in comparison with those of the control group. I 2. At second, we observed effects of Injinho-tang and Haninjinho-tang on liver damage induced by alcohol. lnjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), liver weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase) in comparison with those of the control group. Conclusion : Reviewing these experimental results, it appears that water extracts from Injinho-tang and Haninjinho-tang have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

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The Effect of Red Ginseng Extracts on Blood Biochemical Parameters, Bone Density and Bone Inorganic Components in Ovariectomized Rats (홍삼추출물이 난소절제 흰쥐의 혈액 생화학적 지표, 골 밀도 및 골무기질에 미치는 영향)

  • Kim, Byung-Weon;Lee, Yoon-Bok;Park, Jae-Seung;Park, Ji-Won;Hwang, Seock-Yeon
    • Journal of Digital Convergence
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    • v.11 no.10
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    • pp.493-505
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    • 2013
  • We investigated the effect of red ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA and Post-Hoc Test. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in red ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). From these results, we knew that within the normal level, red ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone density, bone ash and inorganic components in femur, and index related with bone metabolism.

The Tissues and Blood Components of Opsariichthys uncirostris amurensis in the Muddy Water Area (탁수역에 서식하는 끄리의 조직과 혈액 성분의 변화)

  • Shin, Myung-Ja;Lee, Jong-Eun;Seo, Eul-Won
    • Journal of Life Science
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    • v.17 no.1 s.81
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    • pp.97-104
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    • 2007
  • Present study aims to investigate the effect of muddy water on gill and kidney tissues and blood components of Opsariichthys uncirostris amurensis in Imha reservoir. As a result of observing the gill tissues in muddy water with light and scanning electron microscopes, the edema, the exfoliation of epithelial cells and fusion of the secondary lamellae were observed. The space between gill lamellae was irregular, and a lots of muddy debris around the secondary lamellae were observed. In case of kidney tissues, the size of glomerulus was smaller and thickness of basal membrane was broader and the empty space in Bowman's capsule was wider than those of the control. The blood cells of O. uncirostris amurensis in muddy water were increased in number. Of the white blood cells, acidophilic granulocytes were highly distributed, and the shapes were irregular. Among the plasma components, the concentration of TP, ALB, A/G ratio, TG, CHOL, and AST were low, whereas that of the inorganic materials was high. Based on the above results, it is considered that muddy water possibly involves in the decrease of respiratory and excretory rates, giving rise to secondary lesion of tissues.

Real-time monitoring for blending uniformity of trimebutine CR tablets using near-infrared and Raman spectroscopy (근적외분광분석법과 라만분광분석법을 이용한 트리메부틴말레인산 서방정의 혼합 과정 모니터링)

  • Woo, Young-Ah
    • Analytical Science and Technology
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    • v.24 no.6
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    • pp.519-526
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    • 2011
  • Chemometrics using near-infrared (NIR) and Raman spectroscopy have found significant uses in a variety quantitative and qualitative analyses of pharmaceutical products in complex matrixes. Most of the pharmaceutical can be measured directly with little or no sample preparation using these spectroscopic methods. During pharmaceutical manufacturing process, analytical techniques with no or less sample preparation are very critical to confirm the quality. This study showed NIR and Raman spectroscopy with principal component analysis (PCA) was very effective for the blending processing control. It is of utmost importance to evaluate critical parameters related to quality of products during pharmaceutical processing. The blending is confirmed by off-line determination of active pharmaceutical ingredient (API) by a conventional method such as high performance liquid chromatography (HPLC) and UV spectroscopy. These analytical methods are time-consuming and ineffective for real time control. This study showed the possibility for the determination of blend uniformity end-point of CR tablets with the use of both NIR and Raman spectroscopy. The samples were acquired from six positions during blending processing with U-type blender from 0 to 30 min. Using both collected NIR and Raman spectral data, principal component analysis (PCA) was used to follow the uniformity of blending and finally determine the end-point. The variation of homogeneity of six samples during blending was clearly found and blend uniformity end-point was successfully confirmed in the domains of principal component (PC) scores.