• 제목/요약/키워드: $^1H$-relaxation

검색결과 248건 처리시간 0.022초

T2 Relaxographic Mapping using 8-echo CPMG MRI Pulse Sequence

  • E-K. Jeong;Lee, S-H.;J-S. Suh;Y-Y wak;S-A. Shin;Y-K. Kwon;Y. Huh
    • 한국자기공명학회논문지
    • /
    • 제1권1호
    • /
    • pp.7-20
    • /
    • 1997
  • The mapping of the spin-spin relaxation time T2 in pixed-by-pixel was suggested as a quantitative diagnostic tool in medicine. Although the CPMG pulse sequence has been known to be the best pulse sequence for T2 measurement in physics NMR, the supplied pulse sequence by the manufacture of MRI system was able to obtain the maximum of 4 CPMG images. Eight or more images with different echo time TEs are required to construct a reliable T2 map, so that two or more acquisitions were required, which easily took more than 10 minutes. 4-echo CPMG imaging pulse sequence was modified to generate the maximum of 8 MR images with evenly spaced echo time TEs. In human MR imaging, since patients tend to move at least several pixels between the different acquisitions, 8-echo CPMG imaging sequence reduces the acquisition time and may remove any misregistration of each pixel's signal for the fitting T2. The resultant T2 maps using the theoretically simulated images and using the MR images of the human brain suggested that 8 echo CPMG sequence with short echo spacing such as 17∼20 msec can give the reliable T2 map.

  • PDF

Superplastic Deformation in the Low Stress Region

  • Jang, Chun-Hag;Kim, Chang-Hong;Ree, Tai-Kyue
    • Bulletin of the Korean Chemical Society
    • /
    • 제5권2호
    • /
    • pp.73-78
    • /
    • 1984
  • Superplastic alloys generally exhibit a three-stage sigmoidal variation of stress (f) with strain rate (s), the stages being named region 1, 2 and 3 according to the increasing order of stress or strain rate. In the recent years, two different types of papers have been published on the plastic deformation of Zn-22% Al eutectoid in region Ⅰ differing in strain-rate sensitivity m (= dln f/dln s). In this paper, the data of the two groups have been analysed by applying Kim and Ree's theory of superplastic deformation. (1) We obtained the parametric values of $X_{gj}/{\alpha}_{gj}\;and\;{\beta)_{gj}$ (g: grain boundary, j = 1,2 indicating flow units) appearing in Kim and Ree's theory [Eq. (2a)]. (2) It was found that the value of $X_{g^2}/{\alpha}_{g^2}$ is small for the group data with small m, i.e., ${\alpha}_{g^2}$, which is proportional to the size of flow unit g2, is large whereas ${\alpha}_{g^2}$ is small for the groups data with large m, i.e., the size of the flow unit g2 is small. In other words, the two types of behavior occur by the size difference in the flow units. (3) From the ${\beta}_{gj}$ value, which is proportional to the relaxation time of flow unit gj, the ${\Delta}H_{gj}^{\neq}$ for the flow process was calculated, and found that ${\Delta}H_{g^2}^{\neq}$ is large for the group data with small m whereas it is small for the group data with large m. (4) The flow-unit growth was studied, but it was concluded that this effect is not so important for differentiating the two groups. (5) The difference in ${\alpha}_{g^2}$ and in the growth rate of flow units is caused by minute impurities, crystal faults, etc., introduced in the sample preparation.

Positive impact of integrated amrita meditation technique on heart rate, respiratory rate and IgA on young healthy adults

  • Vandana, Balakrishnan;Saraswathy, Lakshmiammal;Suseeladevi, Gowrikutty K.;Sundaram, Karimassery Ramaiyer;Kumar, Harish
    • 셀메드
    • /
    • 제3권2호
    • /
    • pp.13.1-13.6
    • /
    • 2013
  • The objective of the current study was to find out the effect of Integrated Amrita Meditation Technique (IAM) on blood pressure (BP), heart rate (HR), respiratory rate (RR) and IgA. One hundred and fifty subjects were randomized into three groups IAM, Progressive Muscle Relaxation (PMR) and Control. Baseline values were collected before giving the training for all the subjects and the IAM and PMR groups were given training in the respective techniques. BP, HR, RR and IgA were recorded manually at 0 h, 48 h, 2 months and 8 months after the first visit. HR was found to be reduced in the IAM group 48 h onwards and the fall sustained till 8 months (p < 0.05). IAM group showed significant drop when compared to the PMR group and control group in all the subsequent visits (p < 0.05). RR decreased significantly in the IAM group in the third and fourth visits (p < 0.05). RR of IAM showed significant decrease when compared to PMR and control from the third visit onwards. IgA showed significant increase in comparison with PMR and control in the third and fourth visits. BP did not show any difference in any of the visits. There was subject dropout from randomization to completion of the study, in all the three groups. The significant decrease in HR and RR and increase in IgA in the IAM group when compared to the PMR and control group shows the efficacy of the technique in reducing the physiological stress indicators for up to 8 months.

수직벽 하부에 있는 틈새 후방의 유동특성에 관한 실험적 연구 (An Experimental Study of Flow Characteristics Past vortical wall with Bottom Gap)

  • 조대환;이경우;오경근
    • 해양환경안전학회:학술대회논문집
    • /
    • 해양환경안전학회 2005년도 추계학술대회지
    • /
    • pp.153-158
    • /
    • 2005
  • 표면에 부착된 수직벽 후방의 난류전단흐름을 입자영상유속계를 이용하여 조사하였다. 하부 틈새를 갖는 수직벽 후류영역에서는 박리 후 비정상적인(unsteady) 재순환 영역이 형성되었으며, 약 x=3H위치에서 전단층의 재부착 및 난류경계층으로의 재발달 과정이 나타났다. 수직벽 직전의 오목한(concave) 유선곡률과 수직벽 후방의 볼록한(convex)유선곡률의 영향은 수직벽 주위에서 가장 크게 나타나고, 하류로 나아감에 따라 전단층 주위 유체의 유입 등으로 그 영향이 박리 전단층 내에서 커다란 와구조가 연속적으로 발생하였다.

  • PDF

Chiller용 냉매 CFC-11과 대체냉매 HCFC-123의 전기장을 사용한 핵비등 열전달 촉진에 관한 연구 (An Experimental Study of Nucleate Boiling Heat Transfer With EHD Technique in CFC-11 and HCFC-123)

  • 곽태희;김주형;정동수;김종보;차태우;한창섭
    • 설비공학논문집
    • /
    • 제6권4호
    • /
    • pp.365-379
    • /
    • 1994
  • Pool boiling experiments were carried out to study the effect of electric field on nucleate boiling heat transfer. CFC-11 and its alternative HCFC-123 were used as working fluids. Boiling on both single tube and a bundle of five tubes was investigated. Heat flux varied from 5 to $25kW/m^2$ while the applied voltage changed from 0 to 1kV. The results showed that at low heat flux where boiling was not present or very weak, electric field-induced forced convection helped increase the heat transfer coefficients of CFC-11 and HCFC-123 significantly(4-15 times increase). However, at higher heat flux, nucleate boiling of CFC-11 which is a highly dielectric fluid, was not affected significantly by the application of electric field. In contrast to CFC-11, even at high heat flux, nucleate boiling of CFC-11 which has a relatively larger electric conductivity than CFC-11, was vigorously increased up to 2-4 times. The additional power required to apply the electric field was 1-2% of the total power consumption by the heater. The increase in overall heat transfer coefficient of evaporators with HCFC -123 was about 40%, suggesting a considerable reduction in evaporator size with EHD technique.

  • PDF

소동물용 뇌자도 측정 시스템 개발 (Development of a Magnetoencephalograph System for Small Animals)

  • 김지은;김인선;강찬석;권혁찬;김진목;이용호;김기웅
    • Progress in Superconductivity
    • /
    • 제13권1호
    • /
    • pp.18-23
    • /
    • 2011
  • We developed a four-channel first order gradiometer system to measure magnetoencephalogram for mice. We used double relaxation oscillation SQUID (DROS). The diameter of the pickup coil is 4 mm and the distance between the coils is 5 mm. Coil distance was designed to have good spatial resolution for a small mouse brain. We evaluated the current dipole localization confidence region for a mouse brain, using the spherical conductor model. The white noise of the measurement system was about 30 fT/$Hz^{1/2}$/cm when measured in a magnetically shielded room. We measured magnetic signal from a phantom having the same size of a mouse brain, which was filled with 0.9% saline solution. The results suggest that the developed system has a feasibility to study the functions of brain of small animals.

심자도 측정을 위한 SQUID 센서 기술의 개발 현황 (Review of SQUID Sensors for Measuring Magnetocardiography)

  • 이용호;김진목;유권규;김기웅;권혁찬
    • Progress in Superconductivity
    • /
    • 제13권1호
    • /
    • pp.1-6
    • /
    • 2011
  • Measurement of magnetic signals generated from electric activity of myocardium provides useful information for the functional diagnosis of heart diseases. Key technical component of the magnetocardiography (MCG) technology is SQUID. To measure MCG signals with high signal-to-noise ratio, sensitive SQUID magnetic field sensors are needed. Present magnetic field sensors based on Nb SQUIDs have field sensitivity good enough to measure most of MCG signals. However, for accurate measurement of fine signal pattern or detection of local atrial fibrillation signals, we may need higher field sensitivity. In addition to field sensitivity, economic aspect of the SQUID system is also important. To simplify the SQUID readout electronics, the output voltage or flux-to-voltage transfer of SQUID should be large enough so that direct measurement of SQUID output can be done using room-temperature preamplifiers. Double relaxation oscillation SQUID (DROS), having about 10 times larger flux-to-voltage transfers than those of DC-SQUIDs, was shown to be a good choice to make the electronics compact. For effective cancellation of external noise inside a thin economic shielded room, first-order axial gradiometer with high balance, simple structure and long-baseline is needed. We developed a technology to make the axial gradiometer compact using direct bonding of superconductive wires between pickup coil and input coil. Conventional insert has mechanical support to hold the gradiometer array, and the dewar neck has equal diameter with the dewar bottom. Boiling of the liquid He can generate mechanical vibrations in the gradiometer array due to mechanical connection structure. Elimination of the mechanical support, and direct mounting of the gradiometer array into the dewar bottom can reduce the dewar neck diameter, resulting in the reduction of liquid He consumption.

RF 스퍼터링으로 증착된 하이드록시아파타이트 박막의 열처리 특성 (The Heat Treatment Characteristics of Hydroxyapatite Thin Films Deposited by RF Sputtering)

  • 정찬회;이준희;신윤학;김명한;최석환;김승언
    • 한국재료학회지
    • /
    • 제16권4호
    • /
    • pp.218-224
    • /
    • 2006
  • RF sputtering process was applied to produce thin hydroxyapatite(HAp) films on Ti-6Al-4V alloy substrates. The effects of different heat treatment conditions on the hardness between HAp thin films and Ti-6Al-4V alloy substrates were studied. Before deposition, the Ti-6Al-4V alloy substrates were heat treated for 1h at $850^{\circ}C\;under\;3.0{\times}10^{-3}torr$, and after deposition, the HAp thin films were heat treated for 1h at $400^{\circ}C,\;600^{\circ}C\;and\;800^{\circ}C$ under the atmosphere, and analyzed FESEM-EDX, FTIR, XRD, nano-indentor, micro-vickers hardness, respectively. Experimental results represented that the surface defects of thin films decreased by relaxation of internal stress and control of substrate structure followed by heat treatment of substrates before the deposition, and the HAp thin films on the heat-treated substrates had higher hardness than none heattreated substrates before the deposition, and the hardness properties of HAp thin films and Ti-6Al-4V alloy substrates appeared independent behavior, and the hardness of HAp thin films decreased by formation of $VTiO_3(OH),\;{\theta}-Al_{0.32}V_2O_5,\;Al_{0.33}V_2O_5$.

Magnesium에 의한 흰쥐 대동맥 이완 (Magnesium-induced Relaxation in Rat Aorta)

  • 오성숙;이상우;강형섭;김진상
    • 대한수의학회지
    • /
    • 제43권3호
    • /
    • pp.373-382
    • /
    • 2003
  • Magnesium ion ($Mg^{2+}$) is a vasodilator, but little is known about its mechanism of action on vascular system. In vitro, extracellular magnesium sulfate ($MgSO_4$) produced relaxation in phenylephrine (PE) or high KCl-precontracted isolated rat thorocic aorta with (+E) or without (-E) endothelium in a concentration-dependent manner. The $MgSO_4$-induced relaxations were not affected by removal of the endothelium. Pretreatment of +E or -E aortic rings with nitric oxide synthase (NOS) inhibitors ($20{\mu}M$ L-NNA, $100{\mu}M$ L-NAME, $1{\mu}M$ dexamethasone and $400{\mu}M$ aminoguanidine), cyclooxygenase inhibitor ($10{\mu}M$ indomethacin), guanylate cyclase inhibitors ($10{\mu}M$ ODQ and $30{\mu}M$ methylene blue) and $Ca^{2+}$ transport blocker ($10{\mu}M$ ryanodine) did not affect the relaxant effects of $MgSO_4$. $Ca^{2+}$ channel blockers ($0.3{\mu}M$ nifedipine and $0.5{\mu}M$ veropamil) completely decreased the relaxant effects of $MgSO_4$ in +E and -E aortic rings. However, in $Ca^{2+}$-free medium, $MgSO_4$-induced vasorelaxation was potentiated and this response was inhibited by nifedipine. Protein kinase C (PKC) inhibitors ($1.0{\mu}M$ staurosporine, $0.5{\mu}M$ tamoxifen and $0.1{\mu}M$ H7) or PLC inhibitor ($100{\mu}M$ NCDC) markedly decreased the relaxant effects of $MgSO_4$ in +E and -E aortic rings. In vivo, infusion of $MgSO_4$ elicited significant decreases in arterial blood pressure. After intravenous injection of nifedipine ($150{\mu}g/kg$) and NCDC (3 mg/kg), infusion of $MgSO_4$ inhibited the $MgSO_4$-lowered blood pressure markedly. However, after introvenous injection of saponin (15 mg/kg), L-NNA (3 mg/kg), L-NAME (5 mg/kg), indomethacin (2 mg/kg), methylene blue (15 mg/kg) and aminoguanidine (10 mg/kg) failed to inhibit it. These results suggest that endothelial NQ-cGMP or prostaglandin pathway is not involved in vasorelaxant or hypotensive action of $Mg^{2+}$ and that these effects are due to the inhibitory action of $Mg^{2+}$ on the $Ca^{2+}$ channel or PLC-PKC pathway, and are due to the competitive influx of $Mg^{2+}$ and $Ca^{2+}$ through the $Ca^{2+}$ channel.

$LaGaO_3$:$Eu^{3+}$형광체의 합성 및 발광 특성 (Synthesis and Anaiysis of Photohnninescence Properties of $^5D_1$$^7F_1$ Transition in $LaGaO_3$:$Eu^{3+}$ Red Phosphor)

  • 김경화;최윤영;손기선;김창해;박희동;최세영
    • 대한화학회지
    • /
    • 제44권5호
    • /
    • pp.453-459
    • /
    • 2000
  • 최근 정보 표시 소자로 전계 방출 표시 소자(FED),PDP.LCD 등이 주목받고 있다. 음극선 발광 형광체는 FED뿐만 아니라 형광 표시판(VFD) 등이 중요한 핵심 소자이다. 따라서 본 연구에서는 FED에 응용 가능한 새로운 모체 탐색을 시도하였고 $LaGaO_3$모체에 $Eu^{3+}$를 첨가한 적색 형광체를 합성하여 광 특성을 분석하였다. $Eu^{3+}$의 농도에 따른 발광 스펙트럼, 여기 스펙트럼과 잔광 시간 곡선을 통해 $LaGaO_3$: $Eu^{3+}$의PL거동을 규명하였다. 잘 알려진 $Eu^{3+}$ 캐스캐이딩(cascading)과 다중 음향 양자(multiphonon emisson)에 의한 cross-relaxation은 $LaGaO_3$: $Eu^{3+}$ 형광체에서도 확인되었다. 또한, Inokutti-Hirayama식으로 부터 결정된 $Eu^{3+}$ 사이의 다중극자 상호 작용(multipolar interaction)유형은 이중 극자 상호 작용(dipole-dipole interaction)으로 밝혀졌다. 본 연구를 통해 $^5D_0$ 전이의 직접 소광 기구(direct quenching mechanism)를 새롭게 제안하였다. 소광 유형은 농도에 의존하며, 0.2몰 이하에서는 확산 율속 단계에 의한 소광 현상이 우세하다가 0.3몰 이상 부터는 $^5D_0$에서 전하 이동 띠(Charge Transfer Band,CTB)로 전이되는 직접 소광 유형이 지배적이다. 음극선 거동은 800V의 가속 전압하에서 여기시켜 측정하였고, PL거동과 같이 0.125몰일때 가장 큰 615nm의 발광 휘도를 나타내었다.

  • PDF