• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.28 no.8
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• pp.544-549
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• 2015

Since LEDs (light emitting diodes) have many advantages as a light source in vehicle headlamp, such as good reliability, energy and space saving, and flexible headlamp design. On the other hand, the dependence of its performance and life on temperature have great influence on its practical use. In this study, design and fabrication of heat sink for vehicle LED headlamp were performed using thermally-conductive plastics. This study focused on the effective heat sink structure with limited space in the vehicle LED headlamp. We designed two different prototype of heat sink by thermal simulation using SolidWorks program, which had excellent temperature characteristics. The two different prototype of heat sink were fabricated by injection molding with thermally-conductive plastics. The results showed that LED $T_j$ (junction temperature) of sample B (model 1) and sample C (model 1, 2) was below then $165^{\circ}C$ when applying the thermally-conductive plastics in heat sink of vehicle LED headlamp.

• Biomolecules & Therapeutics
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• v.22 no.6
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• pp.525-531
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• 2014

In the present study, we investigated whether apigenin significantly affects tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$)-induced production and gene expression of MUC5AC mucin in airway epithelial cells. Confluent NCI-H292 cells were pretreated with apigenin for 30 min and then stimulated with TNF-${\alpha}$ for 24 h or the indicated periods. The MUC5AC mucin gene expression and mucin protein production were measured by reverse transcription - polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. Apigenin significantly inhibited MUC5AC mucin production and down-regulated MUC5AC gene expression induced by TNF-${\alpha}$ in NCI-H292 cells. To elucidate the action mechanism of apigenin, effect of apigenin on TNF-${\alpha}$-induced nuclear factor kappa B (NF-${\kappa}B$) signaling pathway was also investigated by western blot analysis. Apigenin inhibited NF-${\kappa}B$ activation induced by TNF-${\alpha}$. Inhibition of inhibitory kappa B kinase (IKK) by apigenin led to the suppression of inhibitory kappa B alpha ($I{\kappa}B{\alpha}$) phosphorylation and degradation, p65 nuclear translocation. This, in turn, led to the down-regulation of MUC5AC protein production in NCI-H292 cells. Apigenin also has an influence on upstream signaling of IKK because it inhibited the expression of adaptor protein, receptor interacting protein 1 (RIP1). These results suggest that apigenin can regulate the production and gene expression of mucin through regulating NF-${\kappa}B$ signaling pathway in airway epithelial cells.

• Biomolecules & Therapeutics
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• v.30 no.6
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• pp.540-545
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• 2022

Betulin is a triterpenoid natural product contained in several medicinal plants including Betulae Cortex. These medicinal plants have been used for controlling diverse inflammatory diseases in folk medicine and betulin showed anti-inflammatory, antioxidative, and anticancer activities. In this study, we tried to examine whether betulin exerts a regulative effect on the gene expression of MUC5AC mucin under the status simulating a pulmonary inflammation, in human airway epithelial cells. Confluent NCI-H292 cells were pretreated with betulin for 30 min and then stimulated with phorbol 12-myristate 13-acetate (PMA) for 24 h or the indicated periods. The MUC5AC mucin mRNA expression and mucin glycoprotein production were measured by reverse transcription - polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. To elucidate the action mechanism of betulin, effect of betulin on PMA-induced nuclear factor kappa B (NF-kB) signaling pathway was also investigated by western blot analysis. The results were as follows: 1) Betulin significantly suppressed the production of MUC5AC mucin glycoprotein and down-regulated MUC5AC mRNA expression induced by PMA in NCI-H292 cells. 2) Betulin inhibited NF-κB activation stimulated by PMA. Suppression of inhibitory kappa B kinase (IKK) by betulin led to the inhibition of the phosphorylation and degradation of inhibitory kappa B alpha (IκBα), and the nuclear translocation of NF-κB p65. This, in turn, led to the down-regulation of MUC5AC glycoprotein production in NCI-H292 cells. These results suggest betulin inhibits the gene expression of mucin through regulation of NF-kB signaling pathway, in human airway epithelial cells.

• Journal of Sensor Science and Technology
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• v.5 no.4
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• pp.9-15
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• 1996

In order to display magnetic signals obtained from a magneto-resistance sensor, a direct current magnetometer was designed and its circuit was constructed. The magnetic fields measured by the home-made magnetometer, which showed good functions of automatic ranging, analog output, and vector sensing, were well agreed with those by commercial MAG-01 magnetometer. The measurement range of the magnetometer was $1\;{\mu}T$ to 1.999 mT, the resolution was -132 dB within 1 Hz bandwidth and the measured magnetic fields could be displayed with $3{\cdot}1/2$-digit LED.

• Journal of Microbiology and Biotechnology
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• v.12 no.5
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• pp.838-840
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• 2002

Feeding experiments of various derivatives of p-aminobenzamide to benzastatins-producing Streptomyces nitrosporeus were performed to observe whether new biosynthetic analogs of benzastatins were produced. The supplementation of p-aminobenzoic acid to the culture medium of Strepromyces nitrosporeus led to the production of benzastatin J, a new demethylated derivative of benzastatin B, while production of benzastatins A and B increased and benzastatins C-G were not detected.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.30 no.9
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• pp.577-582
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• 2017

The white light of a hybrid LED is obtained by using red and green organic fluorescent layers made of polymethylmethacrylate (PMMA) films, which function as color down-conversion layers of blue light-emitting diodes. In this research, we studied the fluorescence properties of a red organic fluorophore, employing perylene bisimide derivatives applicable to hybrid LEDs. The solubility, thermal stability, and luminous efficiency are important characteristics of organic fluorophores for use in hybrid LEDs. The perylene fluorescent compounds (1A and 1B) were prepared by the reaction of 4-bromophenol and 4-iodophenol with N,N'-bis(4-bromo-2,6-diisopropylphenyl)-1, 6,7,12-tetrachloroperylene-3,4,9,10-tetracarboxyl diimide (1) in the presence of dimethyl formaldehyde (DMF) at $70^{\circ}C$. The synthesized derivatives were characterized by using $^1H-NMR$, FT-IR, UV/Vis absorption and PL spectra, and TGA analysis. Compounds 1A and 1B showed absorption and emission at 570 nm and 604 nm in the UV/Vis spectrum. We also documented favorable solubility and thermal stability characteristics of the perylene fluorophores in our work. Perylene fluorophore 1, with the 4-bromophenol substituent 1A, exhibited particularly good thermal stability and solubility in organic solvents.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.4
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• pp.343-350
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• 2015

The natural convection heatsink is the most commonly used cooling device, especially for high-power LED lights, because of its reliability and low long-term cost. High power LED lights are generally used in an inclined configuration for street lamps and security lamps. However, it was difficult to estimate the thermal performance of an inclined heatsink, because the results from previous studies are not applicable to the inclined configuration. In this study, we measured the thermal performance of an inclined cylindrical heatsink with plate fins. Various fin numbers, fin heights, base temperatures, and inclination angles ($30^{\circ}$ and $60^{\circ}$) were examined. Based on the experimental results, the Nusselt number correlation is presented. This correlation is applicable when the Rayleigh number, ratio of the fin height to cylinder diameter, and fin number are in the ranges 100,000-600,000, 1/6-1/2, and 9-72, respectively.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.11B
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• pp.1394-1402
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• 2011

This paper describes solar light collecting system which employs parabolic reflector and Fresnel lens and its industrial application. We have introduced second-stage optical system so that it makes optical fiber overcome its numerical aperture limitation and also it makes focused light become collimated, which results in decreased light energy density. As result of these, light collecting efficiency become maximized and the system does not require separate cooling apparatus any more. The developed solar lighting system together with artificial light source like LED has been applied to plant factory as a hybrid lighting source. This makes us save electric energy for artificial lighting during day time. The intensity of LED light in the hybrid lighting system is controlled automatically according to ambient-light-sensor installed in the system so that the light intensity for a plant always keeps the same level no matter how the sun light changes. For a plant factory whose size is 330 square meters, when solar lighting system is applied, 28,080KWh electric energy can be saved per month.2 times.

• Korean Journal of Ecology and Environment
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• v.53 no.3
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• pp.304-310
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• 2020

Smart farm is a high-tech type of plant factory that artificially makes environmental conditions suitable for the growth of plants and manages them to automatically produce the desired plants regardless of seasons or space. This study was conducted by identifying the effects of Hertz and Duty ratio on the photosynthetic rate of ginseng, a medicinal crop, to find the optimal conditions for photosynthetic responses in smart farms. The light sources consisted of a total of 10 chambers using LED system, with 4 R+B(red+blue) mixed lights and 6 R+B+W (red+blue+white) mixed lights. In addition, the Hertz of the R+B mixed light was treated at 20, 60, 180, 540, 1620 and 4860 hz respectively. The R+B+W mixed light was treated with 60, 180, 540, and 1620 hz. Afterwards, experiments were conducted with the duty ratio of 30, 50, and 70%. As a result, the photosynthetic rate of ginseng according to duty ratio and Hertz was the highest at 60 hz when duty ratio was set to 50%. On the other hand, that was the lowest when the duty ratio was 30% at the same 60 hz. In addition, the photosynthetic rates were highest in the R+B mixed light and R+B+W mixed light at 60 hz. Therefore, the condition with the highest photosynthetic rate of ginseng in smart farms is 60 hz when the duty ratio in R+B mixed light is 50%.

• Proceedings of the Materials Research Society of Korea Conference
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• 2003.11a
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• pp.198-198
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• 2003

LED(Light Emitting Diode)는 전기 신호를 빛으로 신호를 보내고 받는데 사용되는 반도체의 일종으로 가정용 가전제품, 리모컨, 전광판, 각종 자동화 기기등에 사용된다. 3색광 백색 LED는 soft-UV 또는 blue 빛을 내는 device 와 RGB 형광체로 이루어져 있다. 현재 연구중인 3색광 백색 LED는 InGaN 또는 GaN 이 RGB 형광체를 여기 시키는것이 대부분이다. 이러한 경우에 유기물과 무기물 형과체가 백색광을 구현하기 위해 사용된다. 유기물의 경우에는 lift-time 이 짧고, 무기물의 경우에는 유해원소인 S, Cd등이 포함되기 때문에 환경오염이 야기된다. 이러한 단점을 보완하기 위해 진화 최적방법을 이용하여 alkali earth borosilicate ((Eu,Mg,Ca,Sr,Ba)$_{x}$ $B_{y}$ S $i_{z}$ $O_{d}$ ) 계열에 $^{Eu3+}$을 도핑하여 고효율 형광체를 합성하였다.