• Title/Summary/Keyword: $[^{18}F]F_2$

Search Result 3,009, Processing Time 0.045 seconds

Quantitative Comparisons between CT and $^{68}Ge$ Transmission Attenuation Corrected $^{18}F-FDG$ PET Images: Measured Attenuation Correction vs. Segmented Attenuation Correction (CT와 $^{68}Ge$ 감쇠보정 $^{18}F-FDG$ PET 영상의 정량적 비교: 측정감쇠보정대 분할감쇠보정)

  • Choi, Joon-Young;Woo, Sang-Keun;Choi, Yong;Choe, Yearn-Seong;Lee, Kyung-Han;Kim, Byung-Tae
    • Nuclear Medicine and Molecular Imaging
    • /
    • v.41 no.1
    • /
    • pp.49-53
    • /
    • 2007
  • Purpose: It was reported that CT-based measured attenuation correction (CT-MAC) produced radioactivity concentration values significantly higher than $^{68}Ge$-based segmented attenuation correction (Ge-SAC) in PET images. However, it was unknown whether the radioactivity concentration difference resulted from different sources (CT vs. Ge) or types (MAC vs. SAC) of attenuation correction (AC). We evaluated the influences of the source and type of AC on the radioactivity concentration differences between reconstructed PET images in normal subjects and patients. Material and Methods: Five normal subjects and 35 patients with a known or suspected cancer underwent $^{18}F-FDG$ PET/CT. In each subject, attenuation corrected PET images using OSEM algorithm (28 subsets, 2 iterations) were reconstructed by 4 methods: CT-MAC, CT-SAC, Ge-MAC, and Ge-SAC. The physiological uptake in normal subjects and pathological uptake in patients were quantitatively compared between the PET images according to the source and type of AC. Results: The SUVs of physiological uptake measured in CT-MAC PET images were significantly higher than other 3 differently corrected PET images. Maximum SUVs of the 145 foci with abnormal FDG uptake in CT-MAC images were significantly highest among 4 differently corrected PET images with a difference of 2.4% to 5.1% (p<0.001). The SUVs of pathological uptake in Ge-MAC images were significantly higher than those in CT-SAC and Ge-MAC PET images (p<0.001). Conclusion: Quantitative radioactivity values were highest in CT-MAC PET images. The adoption of MAC may make a more contribution than the adoption of CT attenuation map to such differences.

Inheritance of Resistance to Phytophthora capsici by Inoculums in Korean Hot Pepper (고추 역병균의 접종원에 따른 역병 저항성의 유전 양식)

  • Soh, Jaewoo;Han, Kyung-Sook;Lee, Sung-Chan;Lee, Jung-Sup
    • Research in Plant Disease
    • /
    • v.18 no.4
    • /
    • pp.317-323
    • /
    • 2012
  • The study aims to identify the pathogenicity of Phytophthora. capsici isolates in major pepper-producing areas in Korea and the inherit genetic pattern of phytophthora blight resistance by inocula. With five kinds of testing materials including 'Kataguma (Sakata Korea)' peppers, a disease-susceptible material, '#308', a phytophthora blight resistance material, 'CM334', and their $F_1$ and $F_2$, respective isolates of P. capsici obtained from Icheon, Eumseong, Buan, Imsil and Yeongyang regions together with six kinds of peppers' inoculum including PA-159 (KACC No.40482) received from Korean Agricultural Culture Collection were used for inoculation. The disease-susceptible material '#308', the resistant material 'CM334' and the non-segregating generation of $F_1$ represented 4.94-5.00, 1.00-1.07, and 1.01-1.08 phytophthora blight incidence respectively in the group comparison by isolate. This result means that the phytophthora blight resistance was clearly distinguished among testing materials in the group comparison by P. capsici isolate. Moreover, $F_2$ segregating generation showed 1.79-2.31 phytophthora blight incidence which turned out to be identical in the group comparison by the six isolates of P. capsici isolate and with similarity between both the resistant and susceptible materials. Thus, the result proved that using the six isolates of P. capsici tested as inocula was suitable to investigate the phytophthora blight resistance. When it comes to group comparison of $F_2$ segregation generation, however, isolates were divided with PA-159 isolate being the center: a group consisting of isolates from Icheon, Buan, and Imsil and a group consisting of Yeongyang and Eumseong isolates with higher pathogenicity. The expected segregation ratio of the phytophthora blight resistance in $F_2$ generation by isolate was analyzed. PA-159 isolate showed 3:1 or 9:3:3:1, indicating that one to two genes were involved. On the other hand, results also proved that there is an interaction of genes since both Eumseong and Yeongyang isolates showed a segregation ratio of 11:5 while the Icheon isolate represented 12:3:1.

THE EFFECTS OF SODIUM FLUORIDE ON SQUAMOUS CELL CARCINOMA CELL LINE CULTURED IN VITRO (실험실 내에서 배양된 편평상피암 세포주에 대한 염화불소의 효과)

  • Park, No-Boo
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.18 no.2
    • /
    • pp.316-322
    • /
    • 1996
  • The effects of Sodium Fluoride on squamous cell carcinoma cell line(SCC-cells) cultured in vitro have been studied with respect to cytotoxicity and induction of chromosome aberrations. Cytotoxicity of NaF on SCC-cells, as determined by a decrease in colony-forming ability, linearly increased with dose of NaF(150-300 ug/ml) or exposure time (3-24h). SCC-cells treated with 30-60ug/ml NaF for 24h were analyzed for chromosome aberrations. A significant increase in the frequency of chromosome aberration at the chromatid level was induced by NaF in a dose-dependent manner. These results suggest that NaF is a toxic substance which inhibit cell proliferation and causes DNA damage in SCC-cells cultured in Vitro.

  • PDF

뫼스바우어 분광학과 $\delta$ M plot을 사용한 Nanocomposite magnet의 자기특성 규명 연구

  • 한종수;김응찬;양충진;박언병
    • Proceedings of the Korean Magnestics Society Conference
    • /
    • 2003.06a
    • /
    • pp.204-205
    • /
    • 2003
  • Nano 결정립 N $d_2$F $e_{l4}$B+F $e_3$B 복합상 자성 리본은 Extractive melt spinner의 wheel speed를 달리하여 제조하였다. 초기 조성은 N $d_4$F $e_{77.5}$ $B_{18.5}$이고, 이후 제조한 자성 리본의 자기특성은 VSM 및 AGM(Alternating gradient magnetometer)으로 측정하였다. wheel speed 1500rpm, $650^{\circ}C$에서 10분간 열처리한 자성 리본에서 $B_{r}$ = 11.73 kG, $_{i}$ $H_{c}$ = 3.082 kOe, (BH)$_{max}$ = 12.28 MGOe의 자기특성이 나타났다. 이러한 자기특성 원인 규명을 위해 $\delta$M plot과 뫼스바우어 분광학을 사용하였다. $\delta$M plot을 통해 exchange coupling은 초미세립 복합상의 잔류자속밀도에 큰 영향을 미치는 것으로 판단된다. 또한, 뫼스바우어 분광학을 통해 경자성상(N $d_2$F $e_{l4}$B)과 연자성상 F $e_3$B의 부피분율비가 7:3 정도일 때 가장 최적의 자기특성을 발현하였다. 이 경우에 초미세립 복합상의 상호작용력이 가장 크게 발현하는 것으로 판단된다.단된다..된다..된다..

  • PDF

Correlation Coefficient of Leaf Breakdown with Some Agronomic Characters in Flue- Cured Tobacco (Nicotiana tabacum L.) (황색종 연초(Nicotiana tabacum L.)에서 엽탈락과 농경적 형질과의 상관)

  • 조수헌;진정의
    • Journal of the Korean Society of Tobacco Science
    • /
    • v.11 no.2
    • /
    • pp.149-155
    • /
    • 1989
  • This study was conducted to obtain the breeding information for the leaf breakdown, and correlation coefficients between leaf breakdown and some agronomic characters in flue-cured tobacco at Taegu Experiment Station, Korea Ginseng & Tobacco Research Institute. NC 95 and NC 2326 were used as parents. The bulk method procedure was used from the F2 to the F4 generations, 54 plants were selected among F4, and 11 lines were selected among 54 F5 which based on high resistance to bacterial wilt compared with NC2326. The entries were composed of parents and 11 F6 advanced lines, and designed in randomized block with 3 replications. Plant seedlings were transplanted in 16 April. The number of breakdown leaf were investigated at flowering stage, 18 June. There were significant difference between NC 95 and NC 2326 for the number of breakdown leaf, number and weight of ground suckers, days to flower, yield and resistance to bacterial wilt, and similar results were appeared among lines. Estimated heritability in the broad-sense ranged from 59.3% to 87.4% for all characters. Most of genetic correlations were higher than phenotypic coefficients between characters. Number of breakdown leaf was positively correlated with days to flower, the number and weight of ground suckers, while it was negative to yield. One line among 11 had few breakdown leaf, low producted ground suckers and high resistance to bacterial wilt. Above results suggest that the number and weight of ground suckers can be use as a selection criterion for leaf breakdown even under the condition without leaf breakdown.

  • PDF

Effect of Self-efficacy Promoting Reducing Alcohol Program on Drinking related Knowledge, Drinking Outcome Expectancy and Problematic Drinking Behavior of Women College Students (자기효능증진 절주프로그램이 음주 여대생의 음주관련 지식, 음주거절 자기효능, 음주결과기대 및 문제음주행위에 미치는 효과)

  • Park, Gyung;Choi, Soon-Hee
    • The Journal of the Korea Contents Association
    • /
    • v.15 no.9
    • /
    • pp.364-373
    • /
    • 2015
  • Purpose: The purpose of this study was to identify the effect of self-efficacy promoting reducing alcohol program on drinking related knowledge, drinking refusal self-efficacy, drinking outcome expectancy and problematic drinking behavior of women college students over 8 scores of AUDIT-K. Methods: Data were collected from 22 students with intervention program in the experimental group and 24 students with no intervention program in the control group and analyzed using ${\chi}^2$, t-test and ANCOVA. Results: The Drinking related knowledge(F=14.33, p<.001) of experimental group was significantly higher than that of control group and the optimistic drinking outcome expectancy(F=18.28, p<.001), and problematic drinking behavior(F=5.57, p=.003) of experimental group were significantly less than those of control group. Conclusion: it is recommended that college students should receive this program to prevent and reduce their drinking behaviors.

Characteristics of Hardening Behavior of Korean Rhus Lacquer by F.T.-I.R. (F.T.-I.R.에 의한 한국산 옷액의 경화거동 특성)

  • Lee, Phil-Woo;Kim, Hyun-Joong
    • Journal of the Korean Wood Science and Technology
    • /
    • v.18 no.1
    • /
    • pp.10-14
    • /
    • 1990
  • 한국산 옻액의 경화거동을 알아보기 위하여 F.T.-I.R. 분석을 수행하였다. Acetone 추출한 urushiol의 F.T.-I.R. peak는 $3,422cm^{-1}$, $2,928cm^{-1}$, $1,622cm^{-1}$, $1,475cm^{-1}$, $1,281cm^{-1}$, $984cm^{-1}$, $947cm^{-1}$, $735cm^{-1}$이었다. 또한, 옻액의 정시경화거동에서 $1,651cm^{-1}$ peak는 urushiol-quinone이 laccase의 촉매작용에 의하여 산화중합한 후 982와 $947cm^{-1}$의 conjugated diene와 결합해서 dimer 형성을 알 수 있었다.

  • PDF

A Study on Speed Loss Estimation Due to Hull Roughness And A/F Paint in Preliminary Ship Design (초기 선박 설계시 반체 제도 및 방오 도료에 기인된 속력 구실 평가에 관한 연구)

  • 박명규;박수송
    • Journal of the Korean Institute of Navigation
    • /
    • v.18 no.2
    • /
    • pp.159-171
    • /
    • 1994
  • Hull roughness due to corrosions of outer hull and had applications on outer hull paints was analyzed theoretically. It's value which was gainable practically, was studied, and estimated power penalty formular correspon-ding to that value were reviewed. Local roughness penalty and roughness texture penalty that paint manahers in ship yard can easily were compared and studied by dotting actual ships in the issued curves. Losses and benifits of hull roughness & the specification choise of A/F paint which managers of ship maintenance were much interested in have been calculated through actual ships. The paper is illustrating that how much the specification choise and managing of A/F paint have effects on fuel consumption of ship in program. It is urgently required that recent developed antifouling paints of new A/F generation should be adopted to new ship building by big shipping companies in view of the environmental protection and the economical maintenance of ships.

  • PDF

Isolation of Polyphenol Compounds from the Leaves of Korean Persimmon (Diospyrus kaki L. Folium) (한국산 감잎로부터 Polyphenol계 생리활성물질 분리)

  • An, Bong-Jeun;Bae, Man-Jong;Choi, Hee-Jin;Zhang, Yun-Bin;Sung, Tae-Soo;Choi, Cheong
    • Applied Biological Chemistry
    • /
    • v.45 no.4
    • /
    • pp.212-217
    • /
    • 2002
  • We purified polyphenols from persimmon leaf and tested their biological activity. The 60% acetone extract was lyophilized and applied to test enzyme inhibition of glucosyltransferase and tyrosinase. GTase was 82.4% inhibited at $1.8{\times}10^{-1}$ mg/ml and tyrosinase 21.7% inhibited at 0.8 mg/ml. The acetone extract was fractionated into F-1, 2, 3, 4, 5 by Sephadex Q-50 gel filtration and the fraction-1 and 2 showed higher enzyme inhibition activity than the other fractions. To the Proteinase K treatment and autoclaving of the two fractions had no effect on the enzyme activity, but these results suggested that active fraction was not protein but phenol ring completed compounds. By Sephadex LH-20, MCI-gel and Bondapak $C_{18}$ column chromatographies, compouds 1, 2, 3 and 4 from F-1 fraction, compounds 5 and 6 from F-2 fraction and compounds 7 , 8 from F-3 fraction were purified and re-crystallized. The purified compounds was assumed to be condensed tannins of frame flavan-3-ol frame on the basis of color reagent reaction and to be a mixture of monomer, dimer and trimer according to TLC analysis.

Theoretical Studies of the Gas-Phase Identity Nucleophilic Substitution Reactions of Cyclopentadienyl Halides

  • Lee, Ik-Choon;Li, Hong-Guang;Kim, Chang-Kon;Lee, Bon-Su;Kim, Chan-Kyung;Lee, Hai-Whang
    • Bulletin of the Korean Chemical Society
    • /
    • v.24 no.5
    • /
    • pp.583-592
    • /
    • 2003
  • The gas phase identity nucleophilic substitution reactions of halide anions (X = F, Cl, Br) with cyclopentadienyl halides (1) are investigated at the B3LYP/6-311+G**, MP2/6-311+G** and G2(+)MP2 levels involving five reaction pathways: σ-attack $S_N2$, β-$S_N$2'-syn, β-$S_N$2'-anti, γ-$S_N$2'-syn and γ-$S_N$2'-anti paths. In addition, the halide exchange reactions at the saturated analogue, cyclopentyl halides (2), and the monohapto circumambulatory halide rearrangements in 1 are also studied at the same three levels of theory. In the σ-attack $S_N2$ transition state for 1 weak positive charge develops in the ring with X = F while negative charge develops with X = Cl and Br leading to a higher energy barrier with X = F but to lower energy barriers with X = Cl and Br than for the corresponding reactions of 2. The π-attack β-$S_N$2' transition states are stabilized by the strong $n_C-{\pi}^{*}_{C=C}$ charge transfer interactions, whereas the π-attack γ-$S_N$2' transition states are stabilized by the strong $n_C-{\sigma}^{*}_{C-X}$ interactions. For all types of reaction paths, the energy barriers are lower with X = F than Cl and Br due to the greater bond energy gain in the partial C-X bond formation with X = F. The β-$S_N$2' paths are favored over the γ-$S_N$2' paths only with X = F and the reverse holds with X = Cl and Br. The σ-attack $S_N2$ reaction provides the lowest energy barrier with X = Cl and Br, but that with X = F is the highest energy barrier path. Activation energies for the circumambulatory rearrangement processes are much higher (by more than 18 kcal $mol^{-1}$) than those for the corresponding $S_N2$ reaction path. Overall the gas-phase halide exchanges are predicted to proceed by the σ-attack $S_N2$ path with X = Cl and Br but by the β-$S_N$2'-anti path with X = F. The barriers to the gas-phase halide exchanges increase in the order X = F < Br < Cl, which is the same as that found for the gas-phase identity methyl transfer reactions.