• Journal of the Chungcheong Mathematical Society
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• v.25 no.1
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• pp.1-18
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• 2012

The aim of this paper is to investigate the superstability of the pexider type sine(hyperbolic sine) functional equation $f(\frac{x+y}{2})^{2}-f(\frac{x+{\sigma}y}{2})^{2}={\lambda}g(x)h(y),\;{\lambda}:\;constant$ which is bounded by the unknown functions ${\varphi}(x)$ or ${\varphi}(y)$. As a consequence, we have generalized the stability results for the sine functional equation by P. M. Cholewa, R. Badora, R. Ger, and G. H. Kim.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.90-99
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• 2020

The effects of positive psychology promoting programs for undergraduate nursing students were evaluated. The study was designed using a nonequivalent control group pretest-posttest design; data were collected between June 22 and September 4, 2019. The participants were 37 nursing students, who were assigned to an experimental group (n=18) and a control group (n=19) at two colleges in D and P city. The positive psychology-promoting program was provided for six weeks (12 sessions, 100~120 min.). The data were analyzed using descriptive analysis, t-test, 𝑥² test, repeated measure ANOVA, and paired t-test with the SPSS/WIN 21.0 program. After receiving the positive psychology-promoting program, a difference in optimism (F=16.74, p<.001), psychological well-being (F=14.69, p<.001), and stress-coping strategy (problem solving; F=4.35, p=.015, social support; F=3.87, p=.028) was observed between the experimental and control groups. The results indicate that the positive psychology-promoting program was effective in increasing optimism, psychological well-being, and stress coping strategy in undergraduate nursing students. These findings will contribute to the development of a program to improve the mental health of undergraduate nursing students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.317-324
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• 2017

The purpose of this study was to identify the effects of social support and self-efficacy on the relationship between the nursing work environment and reality shock among new graduate nurses. The participants were 260 nurses who had worked for less than 1 year at 3 general hospitals and 2 university hospitals, and who were examined from 15 June to 31 August 2015. The data were analyzed by descriptive statistics, simple regression analysis and moderated regression analysis with the SPSS WIN 21.0 program. In the results, the mean scores of the nursing work environment, reality shock, social support and self-efficacy were $3.06{\pm}.313$, $2.73{\pm}.401$, $3.90{\pm}.623$ and $3.73{\pm}.519$, respectively. Social support (F=16.744, p<.001) and self-efficacy (F=40.616, p<.001) had a direct influence on reality shock. Social support (F=7.743, p<.001) and self-efficacy (F=14.676, p<.001) also had a moderating effect on the relationship between nursing work environment and reality shock. Thus, we need to develop a preceptor education standardization and customized mentor program to enhance social support and self-efficacy, which can reduce new graduate nurses' reality shock in the nursing work environment.

• Korean Journal of Agricultural Science
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• v.22 no.2
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• pp.163-169
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• 1995

This study was carried out to examine the genetic constitution of serum proteins and enzymes in Holstein Friesian cattle population. The genetic variants of post-transferrin-2(pTf-2), transferrin(Tf), post-albumin(pAlb), ceruloplasmin(Cp) and amylase-I(Am-I) were analyzed by using PAGE(polyacrylamide gel electrophoresis) and STAGE(starch gel electrophoresis). In serum proteins, the pTf-2 locus were observed to be controlled by codominant alleles designated F and S, and the distribution of genotypes were 76.34, 14.50 and 9.10% for pTf-2 FF, FS and SS types, respectively. The gene frequencies of the pTf-2 F and S allele were 0.836 and 0.164. The Tf locus were found to be controlled by four alleles, Tf A, D1, D2 and E at a single locus, and the distribution of genotypes were 6.11, 32.06, 19.08, 1.53, 10.69, 18.32, 9.92 and 2.29% for Tf AA, AD1, AD2, AE, D1D1, D1D2, D2D2 and D2E type, respectively. The gene frequencies of the Tf A, D1, D2 and E wee 0.321, 0.359, 0.298 and 0.019. The pAlb locus were identified to be genetically controlled by two alleles, pAlb F and S allele, and the distribution of genotypes were 32.06, 29.77 and 38.17% for pAlb FF, FS and SS types, respectively. The gene frequencies of the pAlb F and S allele were 0.461 and 0.531. The Alb locus were observed to be controlled by Alb A and B allele, and the gene frequencies of these were 0.996 and 0.004. In serum enzymes, the Cp locus were found to be controlled by F and S allele, and the distribution of genotypes were 46.57, 27.48 and 25.95% for Cp FF, FS and SS types, respectively. The gene frequencies of F and S allele were 0.603 and 0.394. The Am-I locus were observed to be controlled by Am-I B and C allele, and the distribution of genotypes were 39.69, 21.73 and 38.93% for Am-I BB, BC and CC types, the gene frequencies of Am-I B and C were 0.503 and 0.497, respectively.

• Journal of the Korean Mathematical Society
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• v.52 no.4
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• pp.727-749
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• 2015

We obtain the conditions on ${\beta}$ so that $1+{\beta}zp^{\prime}(z){\prec}1+4z/3+2z^2/3$ implies p(z) ${\prec}$ (2+z)/(2-z), $1+(1-{\alpha})z$, $(1+(1-2{\alpha})z)/(1-z)$, ($0{\leq}{\alpha}$<1), exp(z) or ${\sqrt{1+z}}$. Similar results are obtained by considering the expressions $1+{\beta}zp^{\prime}(z)/p(z)$, $1+{\beta}zp^{\prime}(z)/p^2(z)$ and $p(z)+{\beta}zp^{\prime}(z)/p(z)$. These results are applied to obtain sufficient conditions for normalized analytic function f to belong to various subclasses of starlike functions, or to satisfy the condition ${\mid}log(zf^{\prime}(z)/f(z)){\mid}$ < 1 or ${\mid}(zf^{\prime}(z)/f(z))^2-1{\mid}$ < 1 or zf'(z)/f(z) lying in the region bounded by the cardioid $(9x^2+9y^2-18x+5)^2-16(9x^2+9y^2-6x+1)=0$.

• The Korean Journal of Nuclear Medicine Technology
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• v.12 no.3
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• pp.176-180
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• 2008

Department of Nuclear Medicine in Seoul National University Hospital (SNUH) had developed $^{18}F$-Flumazenil as Benzodiazepine receptor imaging agent for PET diagnosis of Epilepsy. But production Activity of $^{18}F$-Flumazenil is decreased owing to this method has difficult synthesis procedures and pretty long synthesis time. In this study, we can modify synthesizing method to have more simple procedure and less spend time and help to increase production Activity. Old method: Radioactivity was produced by cyclotron was captured by QMA cartridge that was activated. Captured radioactivity was eluted into the reaction vial by using kryptofix solution and delivered. After evaporation of eluent, the azeotrophic drying step repeated two times. tosylflumazenil in anhydrous Acetonitrile was added to a reaction vial while bubbling. The reaction mixture was evaporated until the mixture volume was 0.5 mL. Reaction vial washed with 20 % Acetonitrile and that solution went into the reaction vial. The reaction mixture was loaded to the HPLC loop by hand and purified $^{18}F$-Flumazenil by HPLC column. New method: We used $TBAHCO_3$ solution as a eluent. After the eluent was evaporated, tosylflumazenil in anhydrous acetonitrile was added to a reaction vial and the reaction mixture was bubbled for 15 minutes. It was evaporated until the mixture volume became 0.5 mL. It was loaded to the HPLC loop. In old method, $^{18}F$-Flumazenil was synthesized via 6 steps synthesis procedures in 105 minutes with 30~35% synthesizing yield (non-decay correction) and specific activity was about $0.5{\sim}2{\times}10^5$ Ci/mole. In new method, It had 3 steps synthesis procedures in 53 minutes with 40~45% synthesizing yield and specific activity was about $3{\sim}8{\times}10^5$ Ci/mole. This method leads to improve of minimizing synthesis time, increasing synthesis yield and specific activity. While we can load reaction mixture to the HPLC loop, we can expose high radiation field thanks to used by hand.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.701-707
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• 2023

In PET/CT, the injection volume of ¹⁸F-FDG directly affects the SUV(standard uptake value), which can affect the reading results. Therefore, it is important to inject the correct dose value of ¹⁸F-FDG. In this study, we performed the correlation between the residual radioactivity remaining in the syringe and catheter insertion device according to the number of flushing during ¹⁸F-FDG injection. CRC-25R dose calibrator, catheter insertion devices, 3 cc syringes and 50 cc physiological saline were used in this study, and the results were statistically analyzed. As a result, the total residual radioactivity of the syringe and catheter insertion device remained the highest at 5.84% after two flushing, and the least remained at 1.49% after five flushing. The correlation analysis results showed that the number of flushing had a negative correlation with the residual radioactivity of the syringe at -0.436 and the catheter insertion device at -0.300. As a result of one-way distributed analysis of the average according to the number of flushing, the syringe showed a significant decrease at 4 times, and the catheter insertion device showed a significant decrease at 5 times. However, considering that an average of 0.8% remains in the case of catheter insertion devices, four time flushing seems to be the most appropriate.

• Korean Journal of Radiology
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• v.22 no.3
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• pp.425-434
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• 2021

Objective: To investigate the potential value of ¹⁸F-fluorodeoxyglucose (FDG) PET/CT in predicting the survival of patients with primary tracheal malignant tumors. Materials and Methods: An analysis of FDG PET/CT findings in 37 primary tracheal malignant tumor patients with a median follow-up period of 43.2 months (range, 10.8-143.2 months) was performed. Cox proportional hazards regression analyses were used to assess the associations between quantitative ¹⁸F-FDG PET/CT parameters, other clinic-pathological factors, and overall survival (OS). A risk prognosis model was established according to the independent prognostic factors identified on multivariate analysis. A survival curve determined by the Kaplan-Meier method was used to assess whether the prognosis prediction model could effectively stratify patients with different risks factors. Results: The median survival time of the 37 patients with tracheal tumors was 38.0 months, with a 95% confidence interval of 10.8 to 65.2 months. The 3-year, 5-year and 10-year survival rate were 54.1%, 43.2%, and 16.2%, respectively. The metabolic tumor volume (MTV), total lesion glycolysis (TLG), maximum standardized uptake value, age, pathological type, extension categories, and lymph node stage were included in multivariate analyses. Multivariate analysis showed MTV (p = 0.011), TLG (p = 0.020), pathological type (p = 0.037), and extension categories (p = 0.038) were independent prognostic factors for OS. Additionally, assessment of the survival curve using the Kaplan-Meier method showed that our prognosis prediction model can effectively stratify patients with different risks factors (p < 0.001). Conclusion: This study shows that ¹⁸F-FDG PET/CT can predict the survival of patients with primary tracheal malignant tumors. Patients with an MTV > 5.19, a TLG > 16.94 on PET/CT scans, squamous cell carcinoma, and non-E1 were more likely to have a reduced OS.

• Journal of dental hygiene science
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• v.17 no.2
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• pp.116-122
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• 2017

The purpose of this study was to evaluate the detection ability of secondary caries using qunatitative light-induce fluorescence-digital (QLF-D) device. Twenty bovine teeth with cavity on surface were demineralized during 21 days for secondary caries lesion of cavity wall. After 21 days, cavity was filled using composite resin and cut the specimen in half with disc. Fluorescence loss of lesion on surface by time flow, cross sectional lesion, and lesion of filled or unfilled surface were analyzed using analysis software. ${\Delta}F$ (value of fluorescence loss) of the lesion on surface assessed by the QLF-D increased significantly over time up to 21 days. And ${\Delta}F$ value of lesion of filled surface is significantly lower than that of unfilled surface (p<0.001). ${\Delta}F$ of filled surface is 1.31 times of cross section lesion. The correlation of between ${\Delta}F$ of filled surface lesion and ${\Delta}F$ of cross section lesion was showed low agreement (0.026) and correlation of between ${\Delta}F$ of unfilled surface lesion and ${\Delta}F$ of cross section lesion was showed high agreement (0.613). In conclusion, secondary caries can be detected on surface using QLF-D. However, interference of fluorescence of filling material is the points to be especially considered for exact analysis of secondary caries lesion.

• Phonetics and Speech Sciences
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• v.5 no.4
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• pp.81-90
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• 2013

This study explored how Korean L2 learners of English utilize multiple acoustic cues (VOT and F0) in perceiving and producing the English alveolar stop with a voicing contrast. Thirty-four 18-year-old high-school students participated in the study. Their English proficiency level was classified as either 'high' (HEP) or 'low' (LEP) according to high-school English level standardization. Thirty different synthesized syllables were presented in audio stimuli by combining a 6-step VOTs and a 5-step F0s. The listeners judged how close the audio stimulus was to /t/ or /d/ in L2 using a visual analogue scale. The L2 /d/ and /t/ productions collected from the 22 learners (12 HEP, 10 LEP) were acoustically analyzed by measuring VOT and F0 at the vowel onset. Results showed that LEP listeners attended to the F0 in the stimuli more sensitively than HEP listeners, suggesting that HEP listeners could inhibit less important acoustic dimensions better than LEP listeners in their L2 perception. The L2 production patterns also exhibited a group-difference between HEP and LEP in that HEP speakers utilized their VOT dimension (primary cue in L2) more effectively than LEP speakers. Taken together, the study showed that the relative cue-weighting strategies in L2 perception and production are closely related to the learner's L2 proficiency level in that more proficient learners had a better control of inhibiting and enhancing the relevant acoustic parameters.