• Title/Summary/Keyword: $[^{18}F]F_2$

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A Design of Multi-Channel Capacitive Touch Sensing ASIC for SoC Applications in 0.18 ${\mu}m$ CMOS Process (0.18 ${\mu}m$ CMOS 공정을 이용한 SoC용 정전 용량형 멀티 채널 터치 센싱 ASIC의 설계)

  • Nam, Chul;Pu, Young-Gun;Park, Joon-Sung;Hong, Seong-Hwa;Hur, Jeong;Lee, Kang-Yoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.4
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    • pp.26-33
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    • 2010
  • This paper presents a multi-channel capacitive touch sensing unit for SoC applications. This unit includes a simple common processing unit and switch array to detect the touch sensing input by capacitive-time(C-T) conversion method. This touch sensor ASIC is designed based on the Capacitive-Time(C-T) conversion method to have advantages of small current and chip area, and the minimum resolution of the unit is 41 fF per count with the built-in sensing oscillator, LDO regulator and $I^2C$ for no additional external components. This unit is implemented in 0.18 um CMOS process with dual supply voltage of 1.8 V and 3.3 V. The total power consumption of the unit is 60 uA and the area is 0.26 $mm^2$.

Measurement of Apron Shielding Rate for X-ray and Gamma-ray (X선 및 감마선에 대한 apron의 차폐율 측정)

  • Park, Myeong-Hwan;Kwon, Deok-Moon
    • Journal of radiological science and technology
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    • v.30 no.3
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    • pp.245-250
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    • 2007
  • This research measured the shielding rates of apron 0.25 and 0.5 mmPb for X-ray energy in diagnosis radiation system and gamma-ray energy of $^{99m}Tc$-MDP and $^{18}F$-FDG. X-ray energies were measured on effective energy of $26.2{\sim}45.6\;keV$ when additional filtering plate of 0, 2 mmAl is used within the range of tube voltage $40{\sim}120\;kVp$, and at this time, apron 0.5 mmPb has shown about 5.5% of increase in its shielding rate over 0.25 mmPb at the highest quality. Besides, the aprons of the two types have shown high shielding rate of over 90% for direct X-ray and spatial dose rate. And, in case 0.25 and 0.5 mmPb aprons were used at 140keV of $^{99m}Tc$-MDP, the shielding effects were between 30 and 53%, and at high energy of 511 keV, $^{18}F$-FDG, the shielding effects of apron, $1.3{\sim}3.6%$, were very small.

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Antibacterial evaluation of recombinant lysozyme-HJP24 proteins against various bacterial pathogens, and of its possibility test as a feed additive in piglets (재조합 lysozyme-HJP34 단백질의 다양한 병원성 세균에 대한 항균 효능 및 자돈 사료첨가제의 가능성 평가)

  • Yu, Jeong-Hee;Yu, Yeong-Ju;Kim, Seon-Min;Hur, Jin
    • Korean Journal of Veterinary Service
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    • v.44 no.4
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    • pp.247-256
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    • 2021
  • The recombinant lysozyme-HJL34 proteins were expressed and purified using commercial Escherichia (E.) coli expression system. Stx2e+ F18+ E. coli, Actinobacillus pleuropneumoniae (APP), Streptococcus (S.) suis, and Clostridium (C.) perfringens strains were isolated from pigs. The minimum inhibitory concentrations (MICs) of the recombinant lysozyme-HJP34 proteins were examined by means of the microtiter plate method, according to the NCCLS recommendations. The possibility of its as the alternatives to antibiotics was tested in piglets. The MICs were determined as 75 ㎍/mL, 300 ㎍/mL, 75 ㎍/mL, 35.5 ㎍/m against Stx2e+ F18+ E. coli, APP, S. suis, C. perfringens, respectively. A total of 25 piglets were divied 5 groups. The piglets in group A~C were fed with commercial feed and those in groups D, E were fed with commercial feedstuff. All piglets in groups B~E were challenged with virulent Stx2e+ F18+ E. coli, APP, S. suis strains. Groups C and D were treated with antimicrobial from 24 h after challenge. All piglets in group B died within 3 days after challenge. Among 5 piglets in groups C and D piglets, 80% survived after challenge. Among group E piglets, 60% were alive until the end of this study. Therefore, this study indicates that recombinant lysozyme-HJP34 proteins is a suitable possibility as a feed additive for reduction of diseases by bacterial pathogens in piglet feed.

Biochemical Performance and Quantitative Assessment of F1 Hybrid of Two Ecoraces of Tropical Tasar Silkworm Antheraea Mylitta Drury (Lepidoptera: Saturniidae)

  • Lokesh, Gangadharaiah;Tirkey, Sushma Rani;Srivastava, Ashok Kumar;Kar, Prasant Kumar;Sinha, Manoj Kumar
    • International Journal of Industrial Entomology and Biomaterials
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    • v.26 no.2
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    • pp.67-73
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    • 2013
  • Antheraea mylitta Drury is basically a crossbreeding species, as such it seems to be potentially a good material for the exploitation of heterosis. In the present study F1 hybrid of wild ecorace Laria (L) and semi-domestic Daba (D) was raised and evaluated for various quantitative traits and biochemical parameters during larval stage. Improved fecundity ($+18{\pm}1.8%$ and higher egg hatching rate ($+10.96{\pm}1.3%$) was recorded in the F1hybrid ($L{\times}D$). Biochemical parameters studied in the hemolymph, midgut and fatbody of the larva showed significantly higher (P<0.05) total proteins and carbohydrate concentration besides digestive enzyme activity. Correspondingly SDS-PAGE revealed more number of protein bands in the hemolymph sample of F1s, ranging between 29 kDa to 66 kDa compared to parental lines. The present study demonstrates the positive heterosis effect in the F1 hybrid of Laria ${\times}$ Daba. Biochemical analysis indicates that, there is possibilities of exploitation of hybrids with specific parents targeted for desirable commercial traits (silk yield and fecundity). Moreover, most of these biochemical parameters can be used as markers to analyze the genetic improvement in the tasar silkworms.

The Usefulness of $^{18}F$-FDG PET/CT for Predicting the Response of Locally Advanced Rectal Cancer to Neoadjuvant Chemoradiation Therapy (국소 진행된 직장암의 $^{18}F$-FDG PET/CT를 이용한 항암방사선치료의 반응성 예측)

  • Kang, Jin-Kyu;Kim, Mi-Sook;Choi, Chul-Won;Jeong, Su-Young;Yoo, Seong-Yul;Cho, Chul-Koo;Yang, Kwang-Mo;Yoo, Hyung-Jun;Cheon, Gi-Jeong;Shin, Young-Joo;Seo, Young-Seok
    • Radiation Oncology Journal
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    • v.27 no.3
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    • pp.111-119
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    • 2009
  • Purpose: This study aimed at assessing the value of fluorine-18 fluorodeoxyglucose positron emission tomography ($^{18}F$-FDG PET) for predicting the response of locally advanced rectal cancer to neoadjuvant CRT. Materials and Methods: Between August 2006 and January 2008, we prospectively enrolled 20 patients with locally advanced rectal cancer and who were treated with neoadjuvant CRT at the Korea Institute of Radiological and Medical Sciences. The treatment consisted of radiation therapy and chemotherapy, and this was followed by curative resection 6 weeks later. All the patients underwent $^{18}F$-FDG PET/CT both before CRT and 6 weeks after completing CRT. The measurements of the FDG uptake ($SUV_{max}$), the absolute difference (${\Delta}SUV_{max}$) and the percent $SUV_{max}$ difference (response index, $RI_{SUV}$) between the pre- and post-CRT $^{18}F$-FDG PET/CT scans were assessed. The measurements of the metabolic volume, the absolute difference (${\Delta}$metabolic volume) and the percent metabolic volume difference (response index, $RI_{metabolic\;volume}$) were also assessed. Results: Of the 20 patients who underwent surgery, 11 patients (55%) were classified as responders according to Dworak's classification. The post-CRT $SUV_{max}$ was significantly lower than the pre-CRT $SUV_{max}$. However, there were no significant differences in the $SUV_{max}$ and the metabolic volume reduction between the responders and non-responders. We used a minimum $SUV_{max}$ reduction of 67% as the cut-off value for defining a response, with a sensitivity of 45.5%, a specificity of 88.9%, a positive predictive value of 77% and a negative predictive value of 53.8%. Conclusion: Although there were no statistically significant results in this study, other studies have revealed that $^{18}F$-FDG PET/CT has the potential to assess the tumor response to neoadjuvant CRT in patients with locally advanced rectal cancer.

Comparison and Validation Plan for the Calculation Method of Required Maintenance Float (M/F) (정비대체장비(M/F) 소요산출 방법비교 및 검증방안 연구)

  • Lee, Hak-Jae;Kim, Jae-Hwang;Jung, Jae-Woo;Seo, Mu-Kyung;Kwon, Ki-Sang
    • Journal of Applied Reliability
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    • v.18 no.2
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    • pp.143-152
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    • 2018
  • Purpose: In this paper, we propose calculation methods of Maintenance Float (M/F). Results of each method are compared and verified by using commercial tool (OPUS Suite). As modern weapon systems become more expensive, we need to find the most economical and efficient method to achieve the target operational availability (Ao). Methods: Three kinds of methods (Considering the number of CSP, Applying the Poisson distribution, and Applying M&S Tool) are used to find the number of M/F. Three methods (Considering the number of CSP, Applying the Poisson distribution, and Applying M&S Tool) were used to estimate the required number of M/F. The analysis results were verified by SIMLOX. The cost of equipment calculated by each analysis method was compared and the cause of the difference was analyzed. Conclusion: Ao and cost must be considered to find the optimal number of M/F. In general, it costs more to increase availability. But the cost is not necessarily proportional to Ao. Therefore, it is better to compare the calculation method and determine the final MF quantity.

A Study on Stage Classification of Eight Constitution Questionnaire (팔체질 진단을 위한 단계별 설문지 개발 연구)

  • Lee, Joo-Ho;Kim, Min-Yong;Kim, Hee-Ju;Shin, Young-Sup;Oh, Hwan-Sup;Park, Young-Bae;Park, Young-Jae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.16 no.2
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    • pp.59-70
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    • 2012
  • Objectives : Pulse diagnosis by Expert is the only way to classify 8 Constitutions so the study to supplement classifying method by the questionnaire has developed and modified and ECM-32 System has designed in 2010. But analyzing with Decision tree had many nodes and 32 important questions omitted while processing the data. So this study was to classify the 8 constitution patients into 2 groups first and analyze its characters in consecutive order. Methods : The participants of this study were 1027 patients who classified into one of the 8 constitutions according to pulse diagnosis and answered 251 questionnaires in 2010. They were divided into sympathetic nerve acceleration constitution and parasympathetic nerve acceleration constitution and analyzed with decision tree. Results : The reponses of the questionnaire were analyzed with 4 methods of 5 scales interval method from 0 to 5, Na, Low(1,2), Medium(3), High(4,5), average value, Y/N dichotomy. Average Value had no significance. 1. From the 5 scale interval method 6 questionnaires with 7 nodes (F5e, B1d, F7f, F2a, F1b, C4L) were significant. The accuracy was 92.5%. 2. From L, M, H method 7 questionnaires with 7 nodes(F5e, B1d, F7f, F1a, B1c, C4L, P3d) were significant. The accuracy was 92.5%. 3. From Y/N dichotomy 9 questionnaires with 9 nodes( F5e, B1d, F7f, F1a, B1c, C4L, B1b, P1i, B2a) were significant. The accuracy was 93.18%. Conclusions : Based on this study, Yes or No dichotomy method was most significant and categorized among the 4 methods. Unlike previous studies which used interval scale method only, Y/N dichotomy method was more statistically significant with the questionnaire to supplement the method of pulse diagnosis. For further study by analyzing decision tree method in consecutive order, the patients can be divided into 8 Constitutions with higher significance with less questionnaires.

Usefulness of Dynamic $^{18}F-FDG$ PET Scan in Lung Cancer and Inflammation Disease (폐암과 폐 염증성질환의 동적양전자방출단층검사 (Dynamic $^{18}F-FDG$ PET)의 유용성)

  • Park, Hoon-Hee;Roh, Dong-Wook;Kim, Sei-Young;Rae, Dong-Kyeong;Lee, Min-Hye;Kang, Chun-Goo;Lim, Han-Sang;Oh, Ki-Back;Kim, Jae-Sam;Lee, Chang-Ho
    • Journal of radiological science and technology
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    • v.29 no.4
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    • pp.249-255
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    • 2006
  • Purpose: The diagnostic utility of fluorine-18 2-deoxy-D-glucose positron emission tomograhpy ($^{18}F-FDG $PET) for the non-invasive differentiation of focal lung lesions originated from cancer or inflammation disease by combined visual image interpretation and semi-quantitative uptake value analysis has been documented. In general, Standardized Uptake Value(SUV) is used to diagnose lung disease. But SUV does not contain dynamic information of lung tissue for the glucose. Therefore, this study was undertaken to hypothesis that analysis of dynamic kinetics of focal lung lesions base on $^{18}F-FDG$ PET may more accurately determine the lung disease. So we compared Time Activity Curve(TAC), Standardized Uptake Value-Dynamic Curve(SUV-DC) graph pattern with Glucose Metabolic Rate(MRGlu) from Patlak analysis. Methods: With lung disease, 17 patients were examined. They were injected with $^{18}F-FDG$ over 30-s into peripheral vein while acquisition of the serial transaxial tomographic images were started. For acquisition protocol, we used twelve 10-s, four 30-s, sixteen 60-s, five 300-s and one 900-s frame for 60 mins. Its images were analyzed by visual interpretation TAC, SUV-DC and a kinetic analysis(Patlak analysis). The latter was based on region of interest(ROIs) which were drawn with the lung disease shape. Each optimized patterns were compared with itself. Results: In TAC patterns, it hard to observe cancer type with inflammation disease in early pool blood area but over the time cancer type slope more remarkably increased than inflammation disease. SUV-DC was similar to TAC pattern. In the result of Patlak analysis, In time activity curve of aorta, even though inflammation disease showed higher blood activity than cancer, at first as time went by, blood activity of inflammation disease became the lowest. However, in time activity curve of tissue, cancer had the highest uptake and inflammation disease was in the middle. Conclusion: Through the examination, TAC and SUV-DC could approached the results that lung cancer type and inflammation disease type has it's own difference shape patterns. Also, it has outstanding differentiation between cancer type and inflammation in Patlak and MRGlu analysis. Through these analysis methods, it will helpful to separation lung disease.

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A study on Life Style and Clothing Involvement of Elderly Women (노년기 여성의 라이프 스타일과 의복관여에 관한 연구)

  • 이은실;이명희
    • Journal of the Korean Society of Costume
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    • v.25
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    • pp.233-247
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    • 1995
  • The objectives of this study were to classify the contents of clothing involvement, to group elderly women into life style types. A method of this study was face to face re-search and questionnaire. Questionnaire was comprised of four sections : 18 Likert type items of clothing involvement measure ; 26 Likert type items of life style measure ; 3 items of clothing purchase measure ; and 3 demographic variables. Samples were 215 elderly women(60∼79 years of age) in Seoul, Korea. The data were analyzed using factor analy-sis, cluster analysis, one-way ANOVA, Dun-can's multiple range test,χ2 test. The results of the study were the follow-ings. 1. Four factors of clothing involvement derived by factor analysis : F.1 'clothing pleasure'; F.2 'clothing symbolism' ; F.3 'perceived risk in clothing purchase' ; F.4 'clothing interest'. 2. Four factors of life style derived by factor analysis : F.1 'active-leisure';F.2 'confidence oriented';F.3 'appearance interest';F.4 'house-work interest and community conciousness'. Three types of life style were defined by the cluster analysis of the 4 factors : T.1 'passive stag-nation'; T.3'outside activity'. 3. There were significant differences in clothing involvement factors according to life style types. Outside activity type perceived 'clothing pleasure' highest level among 3 life style types. Outside activity type and house-work and positive living type perceived 'cloth-ing symbolism' and 'clothing interest' higher level than did passive stagnation types. 4. Elderly women high in educational level were more distributed in outside activity type and the low in educational level in passive stagnation types. 5. There were significant relationships be-tween life style types and source of a clothing allowance, clothing purchase frequency, and a companion of dress store.

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The Relationship between Anger Expression and Self-esteem in Nursing College Students (간호대학생의 분노표현과 자아존중감)

  • Cha, Nam Hyun;Seo, Eun Ju
    • Research in Community and Public Health Nursing
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    • v.23 no.4
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    • pp.451-459
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    • 2012
  • Purpose: The purpose of this study was to identify the relationship between anger expression and self-esteem in nursing college students. Methods: A total of 297 subjects aged between 18 and 28 were selected through convenience sampling. Data were collected from March 2 to 25, 2011 using a self-reporting questionnaire. Collected data were analyzed with SPSS/WIN 15.0. Results: Differences in anger expression according to general characteristics were as follows. There were significant differences in violent attitude depending on gender (t=3.003, p<.01). Violent actions differed significantly depending on year in school (F=3.279, p<.05) and whether there is a dual income families (t=-2.23, p<.05). There were significant differences in self-esteem depending on year in school (F=4.553, p<.01), school record (F=15.18, p<.001) and the economic status of the parents (F=4.878, p<.01). There were positive correlations between violent attitude and violent actions, except between violent actions and self-esteem. 10.3% of the variance in violent actions was explained by violent attitude, self-esteem and school in year and perceived acceptance. Conclusion: The findings of this study may be useful in understanding the anger expression of nursing college students and developing more specific programs to improve personality and self-control of the mind.