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F-18 fluorodeoxyglucose positron emission tomography/computed tomography in the infection of heart

  • Kong, Eunjung
    • Journal of Yeungnam Medical Science
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    • v.38 no.2
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    • pp.95-106
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    • 2021
  • Infections involving the heart are becoming increasingly common, and a timely diagnosis of utmost importance, despite its challenges. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a recently introduced diagnostic tool in cardiology. This review focuses on the current evidence for the use of FDG PET/CT in the diagnosis of infective endocarditis, cardiac implantable device infection, left ventricular assist device infection, and secondary complications. The author discusses considerations when using FDG PET/CT in routine clinical practice, patient preparation for reducing physiologic myocardial uptake, acquisition of images, and interpretation of PET/CT findings. This review also functions to highlight the need for a standardized acquisition protocol.

Natural, Nature-based Features (NNbF) - A Comparative Analysis with Nature-based Solutions (NbS) and Assessment of Its Applicability to Korea (자연/자연기반 특징(NNbF) - 자연기반해법(NbS)과 비교분석 및 국내적용성 평가)

  • Hyoseop Woo
    • Ecology and Resilient Infrastructure
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    • v.10 no.2
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    • pp.31-39
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    • 2023
  • NNbF is a newly emerging approach to reduce flood risk in coastal and fluvial areas using natural features or engineered nature-based features with the expectation of co-benefits of provisional, regulating, and socio-cultural services provided by the ecosystem. NNbF is not quite different from existing, related terms based on nature, such as NbS, Eco-DRR, NI, GI, EwN, and BwN, for all these terms include expectation of benefits for human societies by directly utilizing or mimicking nature's ecological functions. If we focus on the comprehensiveness of each term's subject and object, we can say that NbS > NNbF > (Eco-DRR, NI/GI). Among the 18 measures introduced in the NNbF International Guideline in the river and floodplain management category, it was found that measures of wash lands and floodplain restoration, including levee setback/removal and side-channel restoration, seemed to be the most applicable to rivers in Korea. These selected measures could be more effective when river managers purchase riparian lands along river courses by relevant laws for river water-quality protection.

The Effect of Qigong Exercise on SF-36 and Psychological Factors of Middle-aged Obese (기공 운동이 비만인의 건강관련 삶의 질(SF-36)과 심리적 요인에 미치는 영향)

  • So, Wi-Young;Seo, Han-Kyo;Choi, Dai-Hyuk;Shin, Hyun-Jung;Cho, Eun-Hyo;Yoo, Byoung-Wook;Jun, Tae-Won
    • 한국노년학
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    • v.30 no.1
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    • pp.21-30
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    • 2010
  • Obese people experience dissatisfaction of body, depression, anxiety, and emotional disturbance by social prejudice and discrimination, further they represent decline of health-related quality of life. Exercise therapy is recommended as one of the positive treatments to improve the emotional pain of obese people. This study is to provide guideline of exercise prescription for obese people by investigating the effects of qigong exercise on psychological factors such as health-related quality of life (SF-36), self-efficiency, depression, anxiety, and fatigue in obese people. The subjects of this study were 50~60s adults participated in Golden-Wellbeing program at S university in G gu of S city and were devided into exercise (N=17) and control (N=16) group. Qigong exercise was performed twice per week for 12 weeks and SF-36, self-efficiency, depression, anxiety, and fatigue were measured before and after 12 weeks of exercise. In the 8 items of SF-36 before and after 12 weeks of qi-gong exercise, there was no significance in role limitation-emotional (F=0.187, p=0.668), mental health (F=2.043, p=0.163) between groups, but there was significance in physical functioning (F=15.151, p<0.001), role limitation-physical (F=18.278, p<0.001), social functioning (F=4.957, p=0.033), vitality (F=11.485, p=0.002), bodily pain (F=6.623, p=0.015), and general health (F=4.498, p=0.042) between groups. Also, anxiety (F=0.631, p=0.433) was not significant, whereas self-efficiency (F=6.124, p=0.019), depression (F=5.109, p=0.031), fatigue (F=7.998, p=0.008) was significant between groups. Even though qigong is slow motion and low intensity of exercise, it was found that qi-gong has exercise effect which induces mental and psychological improvement through this study.

Characterization of New Antihypertensive Angiotensin I-Converting Enzyme Inhibitory Peptides from Korean Traditional Rice Wine

  • Kang, Min-Gu;Kim, Jae-Ho;Ahn, Byung-Hak;Lee, Jong-Soo
    • Journal of Microbiology and Biotechnology
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    • v.22 no.3
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    • pp.339-342
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    • 2012
  • This study describes the characterization of a new angiotensin I-converting enzyme (ACE) inhibitory peptide from a Korean traditional rice wine. After purification of the ACE inhibitor peptides with ultrafiltration, Sephadex G-25 column chromatography, and successively $C_{18}$ and SCX solid-phase extraction, reverse-phase HPLC, and size exculsion chromatography, two types of the purified ACE inhibitors with $IC_{50}$ values of 0.34 mg/ml and 1.23 mg/ml were finally obtained. The two purified ACE inhibitors (F-1 and F-2) were found to have two kinds of novel oligopeptides, showing very little similarity to other ACE inhibitory peptide sequences. The amino acid sequences of the two purified oligopeptides were found to be Gln-Phe-Tyr-Ala-Val (F-1) and Ala-Gly-Pro-Val-Leu-Leu (F-2), and their molecular masses were estimated to be 468.7 Da (F-1) and 357.7 Da (F-2), respectively. They all showed a clear antihypertensive effect on spontaneously hypertensive rats at a dosage of 500 mg/kg.

Antioxidant Activity and Quality properties of Ginger Jocheong added with Gujeung-gupo Ginger Powder (구증구포 생강 분말을 첨가한 생강 조청의 항산화 활성과 품질 특성)

  • MiKyeong Kim;BokMi Jung;EunRaye Jeon
    • Human Ecology Research
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    • v.62 no.2
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    • pp.327-336
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    • 2024
  • This study was investigated to examine the antioxidant activity and quality characteristics of ginger Jocheong added with Gujeung-gupo ginger powder and the results were as follows. As the amount of Gujeung-gupo ginger powder added into ginger Jocheong increased, the moisture and carbohydrate contents of ginger Jocheong significantly decreased(F=133.33, p<.001) and increased(F=36.15, p<.001), respectively. The content of mineral composition such as K, Ca and Zn showed higher values as the amount of added Gujeung-gupo ginger powder increased. As the amount of Gujeung-gupo ginger powder added into ginger Jocheong increased, sweetness(F=200.00, p<.001), viscosity(F=441.23, p<.001), L value(F=1,458, p<.001), a value(F=44.56, p<.001) and b value(F=203, p<.001) decreased significantly, and pH significantly increased(F=59.18, p<.001). As the amount of Gujeung-gupo ginger powder added into ginger Jocheong increased, total polyphenol content(F=86.015, p<.001), total flavonoid content(F=885.012, p<.001), and DPPH radical scavenging activity(F=75.136, p<.001), ABTS radical scavenging ability(F=145.751, p<.001), and FRAP activity(F=172.242, p<.001) increased. From the above results, the antioxidant activity and quality characteristics of ginger Jocheong added with Gujeung-gupo ginger powder confirmed the potential development of ginger Jocheong with high antioxidant activity.

Action of Ozone on Bacterial Virus f2 (세균성 Virus f2에 대한 Ozone의 불활성작용)

  • 김치경
    • Korean Journal of Microbiology
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    • v.18 no.3
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    • pp.123-132
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    • 1980
  • Bacterial virus f2 and its RNA were examined to elucidate the mode of ozone utilizing sucrose density gradient analysis and electtron microscopic techniques. the inactivation kinetics of the virus f2 by ozonation showed that the viruses were inactivated during the first 5 sec of the reaction and were further inactivated at a slower rate during the next 10 min at 0.09 and 0.8mg/l ozone concentrations. The virus coat was broken by ozonation into many pieces of protein subunits and the adsorption of the viruses to the host pili was inversely related to the extent of the breakage of the virus. The viral RNA was released from the virus particles during ozone, but ozone inactivation of the RNA enclosed in the protein coat could not ruled out the possibility that the RNA was secondarily sheared by a reaction with the broken coat protein.

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A Study on the Strength of Stud Shear Connectors in High Strength Concrete Composite Structures. (고강도 콘크리트 합성구조의 스터드 쉬어콘넥더 내력에 관한 연구)

  • 박복만
    • Journal of the Korean Professional Engineers Association
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    • v.19 no.3
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    • pp.23-30
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    • 1986
  • This study summarizes the results of tests on 18 two-slab push out specimens. The main purpose of tile survey was to evaluate the capacity and behavior of stud shear connectors embedded in high strength normal concrete (F$\sub$c/=260~390kg/$\textrm{cm}^2$). The normal concrete was made with crushed stones and natural sand near the Han River. Two different diameters (ø19mm, ø16 mm) of stud shear connectors were used for push out specimens. The following conclusions were drawn from this study. 1) The shear strength of stud connectors embedded in high strength concrete (F$\sub$c/=260~390kg/$\textrm{cm}^2$) was influenced by tensile stress of the stud shear connectors. The following empirical function described the test results: q$\sub$u/=0.5A$\sub$s/√F$\sub$c/E$\sub$c/$\leq$0.7A$\sub$u/F$\sub$u/ 2) The maximum load in this study was reached at slips varying from 2.5~6mm.

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Usefulness of F-18 FDG PET/CT in Adrenal Incidentaloma: Differential Diagnosis of Adrenal Metastasis in Oncologic Patients (부신 우연종에서 F-18 FDG PET/CT의 유용성: 악성 종양 환자에서 부신 전이의 감별진단)

  • Lee, Hong-Je;Song, Bong-Il;Kang, Sung-Min;Jeong, Shin-Young;Seo, Ji-Hyoung;Lee, Sang-Woo;Yoo, Jeong-Soo;Ahn, Byeong-Cheol;Lee, Jae-Tae
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.5
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    • pp.421-428
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    • 2009
  • Purpose: We have evaluated characteristics of adrenal masses incidentally observed in nonenhanced F-18 FDG PET/CT of the oncologic patients and the diagnostic ability of F-18 FDG PET/CT to differentiate malignant from benign adrenal masses. Materials and Methods: Between Mar 2005 and Aug 2008, 75 oncologic patients (46 men, 29 women; mean age, $60.8{\pm}10.2$ years; range, 35-87 years) with 89 adrenal masses incidentally found in PET/CT were enrolled in this study. For quantitative analysis, size (cm), Hounsfield unit (HU), maximum standardized uptake value (SUVmax), SUVratio of all 89 adrenal masses were measured. SUVmax of the adrenal mass divided by SUVliver, which is SUVmax of the segment 8, was defined as SUVratio. The final diagnosis of adrenal masses was based on pathologic confirmation, radiologic evaluation (HU<0 : benign), and clinical decision. Results: Size, HU, SUVmax, and SUVratio were all significantly different between benign and malignant adrenal masses.(P < 0.05) And, SUVratio was the most accurate parameter. A cut-off value of 1.0 for SUVratio provided 90.9% sensitivity and 75.6% specificity. In small adrenal masses (1.5 cm or less), only SUVratio had statistically significant difference between benign and malignant adrenal masses. Similarly a cut-off value of 1.0 for SUVratio provided 80.0% sensitivity and 86.4% specificity. Conclusion: F-18 FDG PET/CT can offer more accurate information with quantitative analysis in differentiating malignant from benign adrenal masses incidentally observed in oncologic patients, compared to nonenhanced CT.

Microstructure and Microwave Dielectric Properties of (1-x)Mg4Ta2O9-xTiO2(x=0\sim0.9) Ceramics ((1-x)Mg4Ta2O9-xTiO2(x=0\sim0.9)세라믹스의 미세구조와 마이크로파 유전 특성)

  • 김재식;최의선;이문기;류기원;이영희
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.8
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    • pp.840-845
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    • 2004
  • The microstructure and microwave dielectric properties of $(1-x){Mg}_4{Ta}_2{O}_9-xTi{O}_2(x=0\sim0.9)$ ceramics were investigated. The specimens were prepared by the conventional mixed oxide method with sintering temperature of 140$0^{\circ}C$∼150$0^{\circ}C$. To improve the quality factor and the temperature coefficient of resonant frequency,$ Ti{O}_2(\varepsilon\Gamma=100, Q\times f_\Gamma=40,000 GHz,\ta_f= +450 ppm\diagup^{\circ}C $ was added in ${Mg}_4{Ta}_2{O}_9$ceramics. The dielectric and structural properties were investigated. According to the XRD patterns, $(1-x){Mg}_4{Ta}_2{O}_9-xTi{O}_2(x=0\sim0.9)$ ceramics had the ${Mg}_4{Ta}_2{O}_9$ phase(hexagonal) and ${MgTi}_2{O}_5$phase(orthorhombic). The dielectric constant($\varepsilon_r$). quality($Qtimes{f}_r$${\tau}_f$) of the $(1-x){Mg}_4{Ta}_2{O}_9-xTi{O}_2(x=0\sim0.9)$ ceramics were 8.12∼18.59, 18,750∼186,410 GHz and -36.02∼+3.46 ppm/$^{\circ}C$, respectively.

Different $^{18}$F-FDG Uptake According to Tumor location and Morphology of Cholangiocarcinoma and Its Clinical Implication (담관암의 위치와 형태에 따른 $^{18}$F-FDG 섭취량의 차이와 임상적 의의)

  • Lee, Won-Seok;Lee, Yoon-Jae;Lim, Seok-Tae;Sohn, Myung-Hee;Lee, Seung-Ok
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.317-322
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    • 2009
  • Purpose: $^{18}$F-flurodeoxyglucose (FDG) uptake on positron emission tomography (PET) scan has been found to reflect tumor aggressiveness and prognosis in various types of cancer. However, pattern of FDG uptake in biliary malignancies and its clinical significance have not been studied well. The purpose of this study was to assess the additional value of $^{18}$F-FDG PET in differential diagnosis and prognosis of cholangiocarcinoma (CC) according to the tumor location and tumor morphology. Materials and Methods: From April 2005 to May 2008, eighty two patients (M:F = 55:27, age 66.2$\pm$9.6 yrs) with CC underwent $^{18}$F-FDG PET. For semiquantitative analysis, the maximum standardized uptake value (SUV$_{max}$) was obtained from the primary tumor. The difference of SUV$_{max}$ according to the tumor location and tumor growth pattern, such as scirrhous type, nodular type, polypoid type were compared. Results: Overall sensitivity of PET scan was 81.7% in CC. SUV$_{max}$ on PET scan in intrahepatic CC was significantly higher compared to extrahepatic CC. In extrahepatic CC, polypoid type showed significantly higher SUV$_{max}$ compared to scirrhous type. Conclusion: $^{18}$F-FDG PET may have a significant impact on clinical decision-making and on the management of intrahepatic cholangiocarcinoma. And it is related to the shape of the tumor and the sensitivity of detection is higher in the mass-forming type than in the scirrhous type.