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Evaluation of 18F-FDG PET/CT Image Distortion by NEMA IEC Body Phantom (NEMA IEC Body Phantom을 이용한 18F-FDG PET/CT 영상의 왜곡 평가)

  • Park, jooncheol;Yang, hanjoon
    • Journal of the Korea Safety Management & Science
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    • v.15 no.4
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    • pp.427-433
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    • 2013
  • Recently, 18F-FDG PET based CT scan was a critical examination that the after, before plan diagnosis and treatment of tumors. But, due to the distortion of SUV that should be proportional to the metabolic rate of glucose in the tumor, the other measurement methods are being on study. In this study, compared the degree of distortion of SUV that according to the volume of the tumor analysis ROI and VOI using the NEMA IEC Phantom. The results, the SUVmax, mean value are rapidly decreased with threshold value 500 mm2 interval of the ROI analysis, 1500 mm3 interval of the VOI analysis. When compared SUVmax value SUVmean, ROI and VOI analysis VOI measurements was 1.077 times higher SUVmax was 0.981 times highe compared to the value of the ROI measurement. Compare MTV, SUV 2.0 as measured by the volume of the VOI to Volume showed a slightly higher results(Volume / MTV = $93.4 %{\pm}14.8 %$). Considering the above results, Tumor evaluation by 18F-FDG PET / CT scan Consider each threshold value should be analyzed due to larger SUV's Distortion depending on the size of the tumor. VOI analysis is recommended. because it showed the VOI analysis is higher than the ROI analysis SUVmax and lower SUVmean due to VOI analysis than once as a measure of the wider area as measured ROI analysis. MTV (R2 = 0.999), a result close to the actual size of the tumor. but, more research is needed in this regard, because SUV according to the standards of value are affected.

Feasibility of Shrinking Field Radiation Therapy through 18F-FDG PET/CT after 40 Gy for Stage III Non-Small Cell Lung Cancers

  • Ding, Xiu-Ping;Zhang, Jian;Li, Bao-Sheng;Li, Hong-Sheng;Wang, Zhong-Tang;Yi, Yan;Sun, Hong-Fu;Wang, Dong-Qing
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.319-323
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    • 2012
  • Objective: To explore the feasibility of shrinking field technique after 40 Gy radiation through 18F-FDG PET/CT during treatment for patients with stage III non-small cell lung cancer (NSCLC). Methods: In 66 consecutive patients with local-advanced NSCLC, 18F-FDG PET/CT scanning was performed prior to treatment and repeated after 40 Gy. Conventionally fractionated IMRT or CRT plans to a median total dose of 66Gy (range, 60-78Gy) were generated. The target volumes were delineated in composite images of CT and PET. Plan 1 was designed for 40 Gy to the initial planning target volume (PTV) with a subsequent 20-28 Gy-boost to the shrunken PTV. Plan 2 was delivering the same dose to the initial PTV without shrinking field. Accumulated doses of normal tissues were calculated using deformable image registration during the treatment course. Results: The median GTV and PTV reduction were 35% and 30% after 40 Gy treatment. Target volume reduction was correlated with chemotherapy and sex. In plan 2, delivering the same dose to the initial PTV could have only been achieved in 10 (15.2%) patients. Significant differences (p<0.05) were observed regarding doses to the lung, spinal cord, esophagus and heart. Conclusions: Radiotherapy adaptive to tumor shrinkage determined by repeated 18F-FDG PET/CT after 40 Gy during treatment course might be feasible to spare more normal tissues, and has the potential to allow dose escalation and increased local control.

Studies on Efficacy of Crude Drug by Processing (II): Sedative Action, Prolonged Effect of Sleeping Time and Effects on Ileum-Smooth Muscle of Anemarrhenae Rhizoma (생약의 수치(修治)에 따른 약호연구(제2보) : 지모(知母)의 진정, 수면효과 및 장관평활근에 미치는 영향)

  • Sul, Soo-Young;Cho, Young-Whan;Rho, Young-Soo;Hong, Nam-Doo;Kim, Sin-Kyu
    • Journal of Pharmaceutical Investigation
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    • v.16 no.1
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    • pp.18-23
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    • 1986
  • Anemarrhenae Rhizoma has been clinically used as a sedative drug in oriental medicine. We observed the sedative action and effect on the movement of isolated-ileum with each water extract of Anemarrhenae Rhizoma (F-I), saline solution treated preparation (F-II) and 25% ethanol treated preparation (F-III). The results obtained were summerized as follows; 1) Sedative actions were recognized with F-I, F-II and F-III. 2) Prolonged effect of sleeping time was recognized significantly with F-I, F-II and F-III. 3) Each fraction of Anemarrhenae Rhizoma showed the released action on the isolated-ileum of the mouse, rat, rabbit and guinea pig, and antagonic action against contraction induced by acetylcholine, barium chloride and histamine. Thus the mechanism in the released action of the smooth muscle was partly considered as the direct dependence of the smooth muscle.

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Formation of Genetic Tumor and Characteristics of Teratoma Shoot from Tobacco Interspecific Reciprocal Hybrids (연초종간 상호교잡에 의한 Genetic Tumor의 유도 및 Teratoma Shoot의 특성)

  • 양덕춘;윤의수;최광태;이정명
    • Korean Journal of Plant Tissue Culture
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    • v.25 no.2
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    • pp.135-139
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    • 1998
  • Reciprocal interspecific hybrids between N. glauca(2n=24) and N. langsdorffii(2n=18) were obtained by intercrossing. One hundred percent of F$_1$ seeds was produced from intercrossing of N. glauca $\times$ N. langsdorffii, whereas the frequency of F$_1$ hybrid seed formation from N. langsdorffii $\times$ N. glauca was very low. However, all the hybrid seeds were germinated well and then grown to normal plantlets. All the plants of F$_1$ hybrids have chromosome number of interspecific hybrids (2n=21). From observation of morphological characteristic, the structure of petrol, leaf, flower, and the morphology of pollen have characteristics of F1 hybrid. Spontaneous tumors (genetic tumor) were formed from each F$_1$ hybrid; the genetic tumor arose at the reproductive phase when the maternal type of F$_1$ hybrid came from N. glauca, while the genetic tumor arose only after reproductive phase when the maternal type of F$_1$ hybrid came from N. langsdorffii. The genetic tumor actively proliferated on hormone-free medium and produced numerous teratoma shoots. In addition, normal leaf or stem explants of F$_1$ hybrid produced calli on hormone-free medium after 15 days of culture, the calli produced new numerous teratoma shoots after 30 days. The frequency of teratoma shoot formation from rnterspecific hybrid was higher in the N. glauca $\times$ N. langsdorffii than in the N. langsdorffii $\times$ N. glauca. Root development from the teratoma shoots was hardly obtained. Teratoma shoots without roots in vitro can form genetic tumor at the vegetative growth phase after tissue culture.

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Establishment of standards for evaluation of health related fitness according to the working styles of male manufacturing workers (남성 제조업 근로자의 근무형태에 따른 건강 체력 평가기준 설정)

  • Ka, Sung-Soon;Lee, Gyu-Seung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.8
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    • pp.190-199
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    • 2017
  • The purpose of this study is to propose the standard of health-related fitness evaluation according to the working styles of male manufacturing workers. The subjects were 15,329 male manufacturing workers aged from 40 to 59 years old who had taken a health-related fitness test by K Institution. Health-related fitness components are cardiorespiratory endurance, muscular strength, muscular endurance, flexibility and body composition. We measured Vo2max, grip strength, sit-up, trunk flexion forward, and body fat percentage to ascertain each component. Data were analyzed with Two-way ANOVA, T-test, One-way ANOVA(Scheffe) and Percentile using SPSS version 18.0 program. The analysis results are as follows. First, the health-related fitness of manufacturing workers varied significantly according to their working styles(maximum oxygen uptake : F=88.67(p<.001), grip strength : F=20.09(p<.001), sit-up : F=42.06(p<.001), trunk flexion forward : F=69.44(p<.001), body fat percentage : F=136.75(p<.001)).Therefore, the evaluation standard was set based on the percentile of health fitness items. Second, the average Vo2max, grip strength, and trunk flexion forward of blue-collar workers were higher than those of white-collar workers at all ages. On the other hand, the average sit-up and body fat percentage of white-collar workers were higher than those of blue-collar workers at all ages. Third, these evaluation criteria differed greatly when compared with the results of the National Physical Fitness Survey. Therefore, we have confirmed that the evaluation criteria should be applied differently according to the working style of a worker when evaluating his health-related fitness.

Influential factors of Health-related Quality of Life of Women Merchants at Traditional Markets (전통시장 여성상인의 건강관련 삶의 질에 미치는 영향요인)

  • Bae, Young Sil
    • Journal of Korean Public Health Nursing
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    • v.34 no.3
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    • pp.355-367
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    • 2020
  • Purpose: This study aims to identify factors influencing the health-related quality of life among women merchants at traditional markets. Methods: Participants in this cross-sectional descriptive study included 121 women merchants. Data were collected from May 01 to June 30, 2019 using the patient health questionnaire-9 (PHQ-9), psychosocial well-being index-short form (PWI-SF), subjective health status, and HRQoL. Selected data were analyzed using descriptive statistics, Pearson's correlation coefficient, and stepwise multiple regression by applying the SPSS/WIN program 22.0. Results: The HRQoL was significantly different by age (F=5.87, p=.001), education (F=2.98, p=.022), working period (F=4.70, p=.004), exercise (t=2.20, p=.030), chronic disease (t=-2.57, p=.011), BMI (F=5.04, p=.008), depression (F=4.70, p=.004), stress (F=7.82, p<.001), and subjective health status (F=7.91, p=.001). Factors influencing the HRQoL for women merchants included BMI (β=-.35, p<.001), subjective health status (β=.33, p<.001), and stress (β=-.18, p=.021). The explanation power of this regression model was 29.8% (F=5.51, p<.021). Conclusion: BMI, subjective health status, and stress affect the HRQoL of the subjects evaluated. Therefore, there is a need for health management programs that may decrease stress, control the BMI, and improve the subjective health status of women merchants at traditional markets.

Wilt of Perilla Caused by Fusarium spp.

  • Kim, Woo-Sik;Kim, Wan-Gyu;Cho, Weon-Dae;Yu, Seung-Hun
    • The Plant Pathology Journal
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    • v.18 no.5
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    • pp.293-299
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    • 2002
  • A survey of Fusarium wilt of perilla was conducted in 12 locations in Korea from 1999 to 2001. The disease occurred in 74 out of 187 fields in the 12 locations surveyed, and incidence of the disease reached up to 30% at its maximum in some perilla fields in Seosan and Dangjin. Incidence of the disease in the other locations ranged from 0.2 to 20%. A total of 327 isolates of Fusarium spp. were obtained from stems and roots of the diseased perilla plants. The isolates were identified based on their morphological characteristics. Out of the 327 isolates of Fusarium, 277 isolates from 12 locations were identified as F. oxysporum, 11 isolates from three locations as F. solani,17 isolates from two locations as F. equiseti, 4 isolates from one location as F. avenaceum and 6 isolates from one location as F. subglutinans. The other 12 isolates of Fusarium from four locations were unidentified. Twelve isolates of F. oxysporum and two isolates each of the other Fusarium spp. were tested for their pathogenicity to five cultivars of perilla. Seven isolates of F. oxysporum were strongly pathogenic to some perilla cultivars, but the other five isolates were weakly or not pathogenic. One isolate of F. solani was strongly pathogenic to all the perilla cultivars tested, but another isolate was not pathogenic. All the isolates of F. equiseti, F. avenaceum, and F. Subglutinans tested were not pathogenic to any of the perilla cultivars tested. Symptoms on the perilla plants induced by artificial inoculation with strongly pathogenic isolates of F. oxysporum and F. solani appeared as wilt, stem blight, and root yet, which were similar to those observed in the fields. The isolates which induced symptoms by artificial inoculation were re-isolated from the lesions of the perilla plants inoculated. All the isolates of F. oxysporum tested were not pathogenic to eight other crops inoculated. Results of this study reveal that F. oxysporum is the main pathogen of perilla wilt and that it is host specific to perilla. forma specialis of F. oxysporum causing wilt of perilla is proposed as perillae.

A Study of Factors influencing Health Promotion Lifestyle in Women College Students (비건강 관련 학과 여대생의 건강증진생활양식과 영향요인)

  • Yoo, Kyung-Hee;Cho, Kyung-Mi
    • The Journal of Korean Academic Society of Nursing Education
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    • v.18 no.2
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    • pp.343-352
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    • 2012
  • Purpose: The purpose of this study was to identify the factors influencing Health Promotion Lifestyle Profile of women college students. Methods: The sample consisted of 248 women college students in P city. Self report questionnaires were used to measure the variables. In data analysis, SPSSWIN 20.0 program was utilized for descriptive statistics, Pearson's correlation coefficients, and regression analysis. Results: The mean score for Health Promotion Lifestyle Profile was 2.27. In the the highest subcategories, the highest degree of performance was interpersonal relationships and the lowest degree was health responsibility. Health Promotion Lifestyle Profile was significantly different according to religion (F=3.48, p=.017), economic state(F=3.01,p=.031), perceived health state(F=8.07, p<.001), exercise frequency (F=16.02, p<.001), and self-rated knowledge about health (F=21.08, p<.001). In regression of analysis, perceived health state, exercise frequency, and self-rated knowledge about health were significant predictors explaining 30.5%. Conclusion: This study suggests that perceived health state, exercise frequency, and self-rated knowledge about health are significantly influencing factors in Health Promotion Lifestyle Profile in women college students. Therefore, the strategies of nursing intervention which improve these variables must be developed for women college students.

A Study of Purchase behavior and Wearing sensation of F/W Season Knit Wear (추동용 니트웨어 구매행동과 착용감에 관한 연구)

  • Park, Sun-Chun;Lee, Young-Ju
    • Korean Journal of Human Ecology
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    • v.18 no.2
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    • pp.431-439
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    • 2009
  • This research aims to invest consumers' purchase behavior and preference of F/W season knit wear to prepare for basic data in producing competitive knit wear which can meet consumers' demands. The results are as follows: 1. Consumers in their twenties are largely purchasing their knit wear at bonded clothing shops, consumers in their thirties at outlet stores and consumers in their forties and fifties at department stores. As for preferred materials in knit wear, the twenties like 100% of cotton, the thirties mixed wool, and the forties and the fifties 100% of wool. Across all age groups, they prefer knit wear pattern with no figures, while they consider its design and color as important factors in purchasing F/W knit wear. 2. As for the wearing sensations of F/W knitwear of three age groups, there are not significant differences in other factors except a factor of 'jacket length'. 3. As for the fitting sensation about F/W knit wear, consumers with 'thin' somatotype feel high comfort in the factor of 'girth', while consumers with standard somatotype feel high satisfaction in the factor of 'length'.

Thermal resistance effect of graphene doped zinc oxide nanocomposite in fire retardant epoxy coatings

  • Rao, Tentu Nageswara;Hussain, Imad;Riyazuddin, Riyazuddin;Koo, Bon Heun
    • Journal of Ceramic Processing Research
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    • v.20 no.4
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    • pp.411-417
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    • 2019
  • Graphene doped zinc oxide nanoparticles (G-ZnO) were prepared using modified hummer's technique together with the ultrasonic method and characterized by field emission scanning electron microscopy (FESEM), X-ray powder diffraction (XRD), fourier-transform infrared spectroscopy (FTIR) and high-resolution transmission electron microscopy (HRTEM). Different samples of epoxy resin nanocomposites reinforced with G-ZnO nanoparticles were prepared and were marked as F1 (without adding nanoparticles), F2 (1% w/w G-ZnO), and F3 (2% w/w G-ZnO) in combination of ≈ 56:18:18:8w/w% with epoxy resin/hardener, ammonium polyphosphate, boric acid, and Chitosan. The peak heat release rate (PHRR) of the epoxy nanocomposites was observed to decrease dramatically with the increasing G-ZnO nanoparticles. However, the LOI values increased significantly with the increase in wt % of G-ZnO nanoparticles. From the UL-94V data, it was confirmed that the F2 and F3 samples passed the flame test and were rated as V-0. The results obtained in the present work clearly revealed that the synthesized samples can be used as efficient materials in fire-retardant coating technology.