• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.104-109
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• 2010

Purpose: $[^{18}F]$Fallypride plays an effective radiotracer for the study of dopamine $D_2/D_3$ receptor occupancy, neuropsychiatric disorders and aging in humans. This tracer has the potential for clinical use, but automated labeling efficiency showed low radiochemical yields about 5~20% with relatively long labelling time of fluorine-18. In present study, we describe an improved automatic synthesis of [$^{18}F$]Fallypride using different base concentration for routine clinical use. Materials and Methods: Fully automated synthetic process of [$^{18}F$]Fallypride was perform using the TracerLab $FX_{FN}$ synthesizer under various labeling conditions and tosyl-fallypride was used as a precursor. [$^{18}F$]Fluoride was extracted with various concentration of $K_{2.2.2.}/K_2CO_3$ from $^{18}O$-enriched water trapped on the ion exchange cartridge. After azeotropic drying, the labeling reaction proceeded in $CH_3CN$ at $100^{\circ}C$ for 10 or 30 min. The reaction mixture was purified by reverse phase HPLC and collected organic solution was exchanged by tc-18 Sep-Pak for the clinically available solution. Results: The optimal labeling condition of [$^{18}F$]Fallypride in the automatic production was that 2 mg of tosyl-fallypride in acetonitrile (1 mL) was incubated at $100^{\circ}C$ for 10 min with $K_{2.2.2.}/K_2CO_3$ (11/0.8 mg). [$^{18}F$]Fallypride was obtained with high radiochemical yield about $66{\pm}1.4%$ (decay-corrected, n=28) within $51{\pm}1.2$ min including HPLC purification and solid-phase purification for the final formulation. Conclusion: [$^{18}F$]Fallypride was prepared with a significantly improved radiochemical yield with high specific activity and shorten synthetic time. In addition, this automated procedure provides the high reproducibility with no synthesis failures (n=28).

• Korean Journal of Organic Agriculture
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• v.23 no.2
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• pp.267-280
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• 2015

The study was conducted to evaluate effects of time and degree of defoliation on growth of 'Wonhwang' pear (Pyrus pyrifolia Nakai) trees managing with low pesticides as well as regrowth of cuttings in vitro. Treatments included degree of defoliation (20% and 60%) with time of defoliation (Early-Aug, End-Aug, and Early-Sep); Early-Aug (20%), Early-Aug (60%), End-Aug (20%), End-Aug (60%), Early-Sep (20%), Early-Sep (60%), and No defoliation. No defoliation and Early-Sep (20%) defoliation increased growth of water sprouts and new shoots, which were improved by delayed defoliation or 20% of defoliation. Total-C, total-N, B, and free sugar contents increased in No defoliation-shoots but decreased in End-Aug (60%)-shoots. Delayed defoliation increased total-C, total-N, and free sugar in shoots, with high contents of C, K, Ca, Mg, and B observed for 20% of defoliation-trees. Fruit yield and weight or fruit length increased in No defoliation, End-Aug (20%) defoliation, and Early-Sep (20%) defoliation, but reduced in End-Aug (60%). Fruit soluble solids content reduced in defoliation in August. Time of defoliation did not affect the fruit yield and fruit quality, while degree of defoliation influenced yield and fruit weight and length. Defoliation at End-Aug (60%) mostly increased the leakage rates of the stem cuttings at $-18^{\circ}C$ and $-21^{\circ}C$ in vitro and reduced the germination rates at $-24^{\circ}C$ and $-27^{\circ}C$. Under comparison of time and degree of defoliation, the Early-Sep defoliation increased germination rates of the stem cuttings at $-27^{\circ}C$ in vitro, and 60% of defoliation decreased the germination rates compared to the 20% of defoliation.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.25 no.1
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• pp.48-57
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• 2015

In a sodium-cooled fast reactor, which is a Generation-IV reactor, refueling is conducted by rotating, but not opening, the reactor head to prevent a reaction between the sodium, water and air. Therefore, an inspection technique that checks for the presence of any obstacles between the reactor core and the upper internal structure, which could disturb the rotation of the reactor head, is essential prior to the refueling of a sodium-cooled fast reactor. To this end, an ultrasound-based inspection technique should be employed because the opacity of the sodium prevents conventional optical inspection techniques from being applied to the monitoring of obstacles. In this study, a ranging inspection technique using a plate-type ultrasonic waveguide sensor was developed to monitor the presence of any obstacles between the reactor core and the upper internal structure in the opaque sodium. Because the waveguide sensor installs an ultrasonic transducer in a relatively cold region and transmits the ultrasonic waves into the hot radioactive liquid sodium through a long waveguide, it offers better reliability and is less susceptible to thermal or radiation damage. A 10 m horizontal beam waveguide sensor capable of radiating an ultrasonic wave horizontally was developed, and beam profile measurements and basic experiments were carried out to investigate the characteristics of the developed sensor. The beam width and propagation distance of the ultrasonic wave radiated from the sensor were assessed based on the experimental results. Finally, a feasibility test using cylindrical targets (corresponding to the shape of possible obstacles) was also conducted to evaluate the applicability of the developed ranging inspection technique to actual applications.

• Korean Journal of Poultry Science
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• v.35 no.4
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• pp.367-373
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• 2009

This experiment was conducted to determine optimum dietary levels of dietary energy and protein for laying performance and egg quality in organic laying hens. In a $2{\times}3$ factorial arrangement, 360 Hy-Line pullets (21 wk of age) were randomly assigned to experimental diets with 2,800, 3,080, and 3,360 kcal of ME/kg of diet, each containing 16 and 18% CP, respectively. Each dietary treatment was replicated 4 times, and feed and water were provided ad libitum. Experimental birds were raised in floor and received 14h of light throughout 52 weeks of experimental period. The birds were observed for feed consumption, egg production, egg weight, egg mass, feed conversion ratio, Haugh unit, shell thickness, and shell color at 30, 50, and 70 wk of age. Egg production, egg weight, and egg mass were higher (P<0.05) in hens receiving diets with 2,800 kcal/kg of ME/kg of feed than those fed diets containing 3,080 and 3,360 kcal of ME/kg of diets. Eggshell breaking strengths were not significantly different among the dietary ME and CP concentrations. Eggshell thickness was higher (P<0.05) in hens receiving diets with 3,360 kcal of ME/kg of feed than those fed diets containing 2,800 and 3,080 kcal of ME/kg of diets at 50 and 70 week. With increasing in dietary energy levels, the concentrations of blood total cholesterol were also significantly increased. Overall, the laying hens fed organic diet of 2,800 kcal ME/kg and 16% CP showed superior egg production than those of other dietary regimens.

• Pediatric Infection and Vaccine
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• v.13 no.1
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• pp.71-77
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• 2006

Purpose : Shigellosis is still an important cause of acute food-borne diarrheal diseases throughout the world. We investigated the transmission routes and clinical course through the outbreak of shigellosis in Mapo-Gu, Seoul. Methods : From October 7th to November 19th in 2005, Mapo-Gu public health center had referred 32 patients with confirmed or suspected shigellosis to the National Medical Center. We had investigated source of infection, epidemiology, laboratory findings, and clinical course of the cases occurred during this outbreak. Results : Among 32 patients, 24 patients had been confirmed with shigellosis, 8 patients had been diagnosed with suspected shigellosis. They ranged in age from 5 months to 12 years old and their mean age was 6.5 years. The clinical manifestations were as follows; diarrhea, fever, abdominal pain and asymptomatic condition. Symptoms had sustained for 3.7 days on the average. S. sonnei were cultured by rectal swab and founded to be resistant to ampicillin and TMP/SMX except to 3rd generation cephalosporin. After treatment with antibiotics such as cefixime and ceftriaxone or imipenem and conservative treatment with electrolyte and fluid replacement for 5~7 days, Stool cultures of the rectal swab grew no Shigella in these cases except 3 cases. Conclusion : An outbreak of shigellosis had occurred in a preschool and elementary school children. From the same results of antimicrobial susceptibility and pulsed-field gel electrophoresis patterns in this study, we suggest that the outbreak of shigellosis in this report had been originated from a single strain. According to all negative results about suspected food and water cultures, we couldn't find out source of infection. Through materials offerred by Mapo-Gu Public Health Center, we presumed the trasmission routes probably were person-to-person.

• Korean Journal of Remote Sensing
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• v.33 no.5_1
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• pp.571-585
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• 2017

The number of spaceborne optical sensors including red-edge band has been increasing since red-edge band is known to be effective to enhance the information content on biophysical characteristics of vegetation. Considering that the Agriculture and Forestry Satellite is planning to carry an imaging sensor having red-edge band, we tried to analyze the current status and potential of red-edge band. As a case study, we analyzed the effect of using red-edge band and tried to find the optimum band width and wavelength region of the red-edge band to estimate leaf area index (LAI) of very dense tree canopy. Field spectral measurements were conducted from April to October over two tree species (white oak and pitch pine) having high LAI. Using the spectral measurement data, total 355 red-edge bands reflectance were simulated by varying five band width (10 nm, 20 nm, 30 nm, 40 nm, 50 nm) and 71 central wavelength. Two red-edge based spectral indices(NDRE, CIRE) were derived using the simulated red-edge band and compared with the LAI of two tree species. Both NDRE and CIRE showed higher correlation coefficients with the LAI than NDVI. This would be an alternative to overcome the limitation of the NDVI saturation problem that NDVI has not been effective to estimate LAI over very dense canopy situation. There was no significant difference among five band widths of red-edge band in relation to LAI. The highest correlation coefficients were obtained at the red-edge band of center wavelength near the 720 nm for the white oak and 710 nm for the pitch pine. To select the optimum band width and wavelength region of the red-edge band, further studies are necessary to examine the relationship with other biophysical variables, such as chlorophyll, nitrogen, water content, and biomass.

• Journal of Science of Art and Design
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• v.3
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• pp.145-177
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• 2001

The artist's interest has been captivated by ecological phenomena in Nature. Her keen captivation has then been focused into plastic art depicting the image of primitive life. The wide sweep of her work encompasses the totality of nature which consists of the human's subconscious power and imagination which she then portrays by organic images. These organic images are in contrast to scientific, mathematical and logical inference and consciousness. This research examines the character of the organic images in modern art by her analysis of some representative works by others. The image is an essential concept in the art which appeared in very different ways and in different perspectives. The image in the artwork appears to be the realistic expression until the early part of the 20th Century. Well into the 20th Century, it began being expressed in various ways such as combined images by imagination which is combined or rejected in the story of artwork. It also began being expressed by transferred images by changed original conditions. It is the main purpose of this research is to study of various expressions of organic images in the artwork of the Post-Modernism era. The character and meaning of organic image painting helps people to approach the human instinct more easily to find out the natural essence. It is also an objective of the organic image to tenderise our human sensibilities, thus helping us to regain vitality and recover our poor humanity in the barren wilderness of modern society. 'Life communion with nature' is a meeting point and common ground for Oriental Philosophy and organic image painting. Through this research, organic image painting is characterised in the four following ways : 1st) Organic image painting seeks regularity and perfection of outer shapes, in contrast to disordered and deformed nature, resulting in organic and biotic formalistic mode of plastic art. 2nd) Organic image painting seeks the formative. 3rd) Organic image painting pursues the priceless dignity of life by researching the formatted arrangement and figure, which contains primitive power of life. 4th) Organic image painting makes crystal clear the power of human and nature, which is a historic and biological phenomenon. This, in turn, exposes the humanistic view of the world from modern society best characterised in lost self-understanding, isolation and materialism. The representative organic image painting artists are Elizabeth Murray, Kusama Yayoi, and Niki do Saint Phalle. Elizabeth Murray used shaped canvas and a round construction of relief works. Kusama Yayoi used Automatistic expressionism originating from the realms of unconsciousness and which is represented by the mass and shape of a water drop. Niki do Saint Phalle shows the transcendence of universal life and anti-life to respect the dignity of life and the eco-friendliness relationship of human and nature in the post-modernism in art history. This is accomplished by surrealistic, symbolic, fantastic and humoristic expression. These three artists' works express the spirit of the organic image in contemporary art. It contains the stream of nature and life to seek not only the state of materialism in the reality, but also the harmonized world of nature and human which has almost lost the important meaning in modern times. Finally, this organic image is the plastic language of the majestic life. It is the romantic idea that the intimacy of nature and the universe and Surrealism, which emphasizes the unconsciousness , is the source of truth and spirit. Also it is influenced by primitive art and abstract art. According to this research, the subject 'Research About Organic Images' is not only an important element in the plastic arts from primitive society to the present, but is also fundamental to an true understanding of Post-Modernism.

• Radiation Oncology Journal
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• v.27 no.2
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• pp.91-102
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• 2009

Purpose: To compare the accuracy and efficacy of EDR2 film, a 2D ionization chamber array (MatriXX) and an amorphous silicon electronic portal imaging device (EPID) in the pre-treatment QA of IMRT. Materials and Methods: Fluence patterns, shaped as a wedge with 10 steps (segments) by a multi-leaf collimator (MLC), of reference and test IMRT fields were measured using EDR2 film, the MatriXX, and EPID. Test fields were designed to simulate leaf positioning errors. The absolute dose at a point in each step of the reference fields was measured in a water phantom with an ionization chamber and was compared to the dose obtained with the use of EDR2 film, the MatriXX and EPID. For qualitative analysis, all measured fluence patterns of both reference and test fields were compared with calculated dose maps from a radiation treatment planning system (Pinnacle, Philips, USA) using profiles and $\gamma$ evaluation with 3%/3 mm and 2%/2 mm criteria. By measurement of the time to perform QA, we compared the workload of EDR2 film, the MatriXX and EPID. Results: The percent absolute dose difference between the measured and ionization chamber dose was within 1% for the EPID, 2% for the MatriXX and 3% for EDR2 film. The percentage of pixels with $\gamma$%>1 for the 3%/3 mm and 2%/2 mm criteria was within 2% for use of both EDR2 film and the EPID. However, differences for the use of the MatriXX were seen with a maximum difference as great as 5.94% with the 2%/2 mm criteria. For the test fields, EDR2 film and EPID could detect leaf-positioning errors on the order of -3 mm and -2 mm, respectively. However it was difficult to differentiate leaf-positioning errors with the MatriXX due to its poor resolution. The approximate time to perform QA was 110 minutes for the use of EDR2 film, 80 minutes for the use of the MatriXX and approximately 55 minutes for the use of the EPID. Conclusion: This study has evaluated the accuracy and efficacy of EDR2 film, the MatriXX and EPID in the pre-treatment verification of IMRT. EDR2 film and the EPID showed better performance for accuracy, while the use of the MatriXX significantly reduced measurement and analysis times. We propose practical and useful methods to establish an effective QA system in a clinical environment.

• Korean Journal of Weed Science
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• v.4 no.1
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• pp.69-78
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• 1984

This study was conducted to select herbicides effective for upland crops and to investigate the cause of crop injury in peanut cultivated with mulching. Crop such as radish (Raphanus acanthiformis Moor.), Chinese cabbage (Brassica raps L.), soybean (Glycine max Merr.), Peanut (Archis hypogaea L.), and marsh mallow (Malva olitoria Nakai) were tolerant to napropamide [2-(${\alpha}$-naphthoxy)-N, N-diethylpropionamide], alachlor [2-chloro-2', 6'-diethyl-N-(methoxymethyl) acetanilide], trifluralin (${\alpha},{\alpha},{\alpha}$-trifluoro-2, 6-dinitro-N, N-dipropylp-toluidine) and nitrofen (2,4-dichlorophenyl-p-nitrophenylether). Napropamide, diphenamide (N, N-dimethyl-2, 2-diphenylacetamide) and alachlor were safe for red pepper (Capsicum annuum L.), eggplant (Solanum melongena L. and tomato (Lycopersicon esculentum Mill.), while trifluralin, nitrofen and chlonitrofen (2,4,6-trichlorophenyl-4-nitrophenyl ether) could be used for water melon (Citrullus battich Forsk.), carrot (Daucus carota L.) and lettuce (Lactuca scariola L.) without crop injury. Out of nine major weed species studied, Capsella bursa-pastoris Medicus was the most resistant species to the herbicides tested. Napropamide and alachlor could not control P. hydropiper, while P. oleracea and C. album were tolerant to diphenamide :and alachlor, respectively. Urea herbicides such as methabenzthiazuron [3-(2-benzothiazolyl)-1,3-dimethylurea], linuron [3-(3, 4-dichlorophenyl~l-methoxy-i-methyl urea], and isoproturon [3-(4-isopropylphenyl) -1, 1-dimethylurea]gave a great injury to the crops studied. The weeding effect was greater for broadleaf weeds than for grasses. Isoproturon and linuron provided good selectivity for marsh mallow and carrot, respectively. In peanut, the crop injury caused by Four herbicides studied was greater when cultivated with mulching than when cultivated without mulching. With dinitroaniline herbicides the crop injury decreased as the gaseous herbicide was removed out of mulching. Alachlor gave little phytotoxicity to peanut grown under mulching condition and nitralin [4-(methylsuphonyl)-2, 6-dinitro-N, N-dipropylaniline] showed less toxicity to the peanut than pendimenthalin (3,4-dimethyl-2, 6-dinitro-N-1-ethyl propylaniline) and trifluralin.

• Korean Journal of Medicinal Crop Science
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• v.11 no.3
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• pp.246-251
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• 2003

Angiotensin converting enzyme(ACE) belongs to the class of zinc protease and plays an important role in the regulation of blood pressure. In this experiment, we investigated the inhibitory activities of ninety four plant extracts on ACE. The extracts were prepared by water and refluxing with 70% and 100% methanol. Among the extracts, two plant extracts such as Cassia tora, Persicaria cochinchinensis Kitagawa showed more than 60% inhibitory activities, and Foeniculum vulgare Gaertner, Scutellaria baicalensis Georgl, Caragana sinica (Buchoz) Rehder, Inula britannica var. chinensis showed $45.2{\sim}49.7%$ inhibitory activities. Twenty eight plant extracts such as Hemerocallis fulva L, Camptotheca acuminata Decne, Inula britannica var. chinensis, Xanthium strumarium, Polygonatum odoratum, Phellodendron amurense Rupr, Coix lachryma-jobi var. mayuen, Prunus ansu, Hibiscus mutabilis L, Thchosanthes kirilowii, Helianthus annuus, Juglans sinensis showed $30.3{\sim}39.7%$ Inhibitory activities. These results suggest that plant extracts which contain high ACE inhibitory activities may be useful as anti-hypertension agents and to the treatment of hypertension.