Objectives : The purpose of this study is to investigate the effectiveness and safety of herbal medicine treatment for acute pharyngitis. Methods : 2 databases(Wangfang Med Online, CNKI) were used to search Randomized Controlled Trials(RCTs) that used herbal medicine treatment for acute pharyngitis, which were published from January 2007 until April 2024. Results : 9 RCTs were selected in this study, and all studies compared herbal medicine alone treatment with western medicine alone treatment. The most frequently used medicine was Toxin-removing medicinal(淸熱解毒藥). Platycodonis Radix(桔梗) was the most frequently used herb. Meta-analysis of nine studies showed that the Total Effective Rate(TER) of treatment group was statistically higher than that of control group(RR:1.12, 95% CI:1.06 to 1.19, p<0.00001, I²=22%). Meta-analysis of 3 studies showed that the total symptom score of treatment group statistically improved than that of control group(MD: -1.00, 95% CI: -1.30 to -0.71, p<0.00001, I²=0%). Mild adverse events such as anorexia were identified in 4 RCTs, but no serious adverse events were reported. Conclusion : Using herbal medicine alone can be more effective and safe in improving acute pharyngitis than using western medicine. But further well-designed studies are needed because heterogeneity between studies existed and the quality of the reports needs to be improved.

Objectives : The aim of this study is to explore the potential of oriental medicine in managing rosacea through the regulation of the autonomic nervous system. Methods : We reviewed studies on the pathophysiology and medical treatment (both western and oriental medicine) of rosacea, as well as the relationship between rosacea and the autonomic nervous system, using four databases: PubMed, OASIS, RISS, and NDSL. Results : Rosacea is a chronic recurrent inflammatory disease characterized by symptoms such as facial flushing, inflammatory papules, and pustules. In Western medicine, symptomatic treatments like vasoconstrictors, doxycycline, and anti-inflammatory drugs are primarily used. According to the pathophysiological mechanisms of rosacea, the autonomic nervous system is closely related, particularly with sympathetic overactivity causing vasodilation and local inflammation in rosacea patients. Additionally, recent studies report that rosacea patients frequently exhibit neuropsychiatric symptoms such as anxiety, depression, and insomnia, which are closely linked to autonomic dysfunction and contribute to the worsening of skin symptoms. However, current studies on the use of oriental medicine for rosacea focus mainly on anti-inflammatory effects at the local level, similar to conventional treatments. Conclusions : Based on the close involvement of the autonomic nervous system in the pathophysiological mechanisms of rosacea and numerous studies showing that oriental medicine can effectively regulate autonomic function, applying such treatments to rosacea patients may improve not only skin symptoms but also the frequently associated neuropsychiatric symptoms like anxiety, depression and insomnia.

Objectives : The purpose of this study is to investigate recent trends in herbal medicine treatment for xerostomia. Methods : We searched for Randomized Controlled Trial(RCT) studies on xerostomia published after 2015 in the China National Knowledge Infrastructure(CNKI). Studies were analyzed based on the year of publication, characteristics of patient groups, herbal medicine treatments and assessment scales. Results : A total of 16 RCT studies were selected. The most frequently used herbal prescription was Zengye Decoction(增液湯). Liriope Tuber(麥門冬), Rehmanniae Radix(生地黃), Glycyrrhizae Radix(甘草), Schisandrae Fructus(五味子), Scrophulariae Radix(玄蔘), Dendrobii Herba(石斛) and Gypsum Fibrosum(石膏) were commonly used herbs. Herbal medicine treatment demonstrated effectiveness in treating xerostomia across all the studies, and this effect was statistically significant. Conclusions : Herbal medicine treatment is effective in treating xerostomia. We anticipate that more high quality studies will be conducted in the future.

Objectives : The purpose of this study is to report on the good results achieved through Korean and western medicine treatment on patients with idiopathic bilateral facial nerve palsy. Methods : We treated a female patient with idiopathic bilateral facial nerve palsy by Korean medicine treatment such as herbal medicine, acupuncture, pharmacopuncture, cupping therapy, and taping therapy. The patient also received western medicine treatment. The treatment effect was evaluated by visual observation through photography, House-Brackmann scale, Yanagihara's scale, standardization of muscular paralysis, and clinical symptoms. Results : After the treatment, muscle movements and clinical symptoms improved, and all facial palsy evaluation indicators also showed improvement. In particular, the House-Brackmann-scale showed improvement from (3/4) to (1/2). Conclusions : This case study shows that Korean-western medicine combination treatment for idiopathic bilateral facial nerve palsy can be effective. We hope that case reports and clinical research will continue to be actively conducted in the future.

Objectives : The purpose of this study is to report a case of a patient with vocal cord contact granuloma that showed improvement through Korean medicine treatment alone. Methods : This study was conducted on patient who has vocal cord contact granuloma for December 23, 2021 to July 30, 2022. The patient was treated with Korean medical treatment including acupuncture, herbal medicine and also corrected lifestyle habits. After treatment, we evaluated the patient's symptoms and used Farwell's grading system to evaluated the size of the granuloma. Results : The patient's symptoms significantly improved and the granuloma disappeared with treatment. Conclusions : It is considered that contact granuloma can be treated without side effects through Korean medical treatment.

Objectives : The purpose of this study is to report the case of contact dermatitis on the burn lesion treated with Korean medicine treatment including Bangpoongtongseongsan gagam, Jaeumganghwatang gagam and pharmacopuncture. Methods : A 28-year-old female patient had complaints of erythema, swelling, pruritus, exudate due to contact dermatitis caused by the band used to treat the left forearm burn lesion from February 10, 2024. The patient visited Dong-Eui Korean medicine university hospital on February 19, 2024, and we treated this patient with herbal medicine, pharmacopuncture, and western medicine. The effects of treatments were evaluated by photo comparision, visual analogue scale(VAS), dermatology life quality index(DLQI) and sleep disorder score. Results : After treatment, the patient's symptoms improved. VAS of pruritus was decreased from 9 to 0, DLQI was decreased 25 to 0 and sleep disorder score was decreased 7 to 0. Conclusions : The results suggest the Korean medicine treatment including herbal medicine and pharmacopuncture could be effective in treating patient with contact dermatitis.

Objective : The purpose of this study is to report that the effect of Korean medical treatments on Miller-Fisher Syndrome with ophtalmoplegia and facial palsy. Methods : We treated a 69-year-old female diagnosed with Miller-Fisher syndrome with ophthalmoplegia, right facial palsy and other symptoms. She received Korean medical treatments such as herbal medicine(Gamiboik-tang), cupping therapy and acupuncture(including pharmacopuncture). The severity of ophthalmoplegia was evaluated by length of the eyeball movement and Scott and Kraft score. The severity of facial palsy was evaluated by Yanagihara score and the severity of other symptoms such as diplopia, dizziness, gait disturbance and neck&shoulder pain was evaluated by VAS. Results : Each neurological symptoms were improved after Korean medical treatments. In case of ophthalmop legia, Scott and Kraft score increase from -4 to 0. There were no restrictions on eye movements. In case of facial palsy, Yanagihara score increased from 10 to 40. Also, other symptoms such as diplopia, dizziness, gait disturbance and neck&shoulder pain was improved. Conclusions : This case report suggests that Korean medical treatments can be effective for Miller-Fisher Syndrome patient with Ophthalmoplegia and Facial Palsy.

Objectives : The purpose of this study is to report the effect of paljin-tang gamibang on facial flushing and xerotic eczema. Methods : We treated a 72-year-old female elderly patient who has facial flushing and xerotic eczema by korean medicine. She was treated from December 13th, 2023 to February 28th, 2024. The treatment applied was acupuncture, pharmacopuncture, herbal ointment and herbal medicine including 'paljin-tang gamibang'. The severity of symptoms was evaluated by photo comparison, visual analogue scale(VAS) and dermatology life quality index(DLQI). Results : After 11 weeks of treatment, the patient's symptoms improved. VAS of pruritus changed 10 to 1, VAS of dryness changed 10 to 1, DLQI changed 25 to 3. Conclusions : This case study showed an effectiveness of Korean medicine treatment including paljin-tang gamibang treated on facial flushing and xerotic eczema.

Objectives : The purpose of this study is to report the case of olfactory disorder treated with Mahwanggachul-tang. Methods : A 58-year-old female patient began to smell the odor of swimming pool water during daily life at the October 2023. Symptoms get worse over time, all smells in daily life felt like bad odors from around January 2024. A brain CT scan was performed to identify other causative diseases, but no abnormal findings were diagnosed. The patient visited the clinic on April 1, 2024, and the patient received Korean medical treatment, including herbal medicine(Mahwanggachul-tang) and acupuncture. The severity of olfactory disorder was evaluated by NRS before and after administration of each treatment term. Results : The patient's symptoms improved and NRS changed 10 to 0. Conclusions : This case study showed an effectiveness of Mahwanggachul-tang treated on Olfactory disorder.