Clinical Endoscopy

  • 제58권4호
  • /
  • Pages.586-594
  • /
  • 2025
  • /
  • 2234-2400(pISSN)
  • /
  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
권호 표지
DOI QR코드

DOI QR Code

Fabrication and mechanical testing of polydioxanone hook cross biodegradable self-expandable enteric stent: impact of fabrication density and mechanical properties of the stent

  • 투고 : 2024.09.16
  • 심사 : 2024.11.18
  • 발행 : 2025.07.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Background/Aims: The mechanical properties of biodegradable stent when fabricated using different number of pins per row of fabrication has been limited. We compared the radial compressive force of polydioxanone (PDO) stent that was fabricated in hook and cross manner, using 13, 17, and 19 pins per row and measure the radial compressive force and ex vivo deployment. Methods: The PDO stents fabricated by the in-house aluminum mandrel were tested for radial force using plate compression until the stent achieved 50% strain. The relationship between compression force and % strain was calculated. Ex vivo testing of stent expansion against short segment stricture was performed in a pig small intestine compared between PDO hook cross PDO stent and braided metallic stent. Results: The stent shortening of 16.40%, 31.20% and 19.24% was observed in 13-, 17-, and 19-pin-per-row, respectively. The maximum force to achieve 50% strain were 0.503, 1.168 and 1.008 N for 13, 17, and 19 pins per row, respectively. The stent fabricated using hook and cross pattern demonstrated higher conformability to anatomical stricture when compared with braided stent. Conclusions: PDO stent fabricated using 17 pins per row demonstrated highest radial force when compared with 13 and 19 pins per row.

키워드

과제정보

The authors would like to thanks Ms. Sarinthorn Boonkruephan for her assistance in laboratory testing. Declaration of generative AI and AI-assisted technologies in the writing process. During the preparation of this work the author(s) used Gemini AI in order to improve the readability and language polishing. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.

참고문헌

  1. Ham YH, Kim GH. Plastic and biodegradable stents for complex and refractory benign esophageal strictures. Clin Endosc 2014;47:295–300. https://doi.org/10.5946/ce.2014.47.4.295
  2. Shim CS, Kim JH, Bok GH. Development of biliary and enteral stents by the Korean Gastrointestinal Endoscopists. Clin Endosc 2016;49:113–123. https://doi.org/10.5946/ce.2016.039
  3. Verschuur EM, Homs MY, Steyerberg EW, et al. A new esophageal stent design (Niti-S stent) for the prevention of migration: a prospective study in 42 patients. Gastrointest Endosc 2006;63:134–140. https://doi.org/10.1016/j.gie.2005.07.051
  4. Yag-Howard C. Sutures, needles, and tissue adhesives: a review for dermatologic surgery. Dermatol Surg 2014;40 Suppl 9:S3–S15. https://doi.org/10.1097/01.DSS.0000452738.23278.2d
  5. Mittal S, Kumar M, Vinayak V, et al. Current trends in the management of surgical wounds. Indian J Contemp Dent 2013;1:62–65. https://doi.org/10.5958/j.2320-5962.1.1.016
  6. Jeong S. Basic knowledge about metal stent development. Clin Endosc 2016;49:108–112. https://doi.org/10.5946/ce.2016.029
  7. Hirdes MM, Vleggaar FP, de Beule M, et al. In vitro evaluation of the radial and axial force of self-expanding esophageal stents. Endoscopy 2013;45:997–1005. https://doi.org/10.1055/s-0033-1344985
  8. Rebelo R, Vila N, Fangueiro R, et al. Influence of design parameters on the mechanical behavior and porosity of braided fibrous stents. Mater Des 2015;86:237–247. https://doi.org/10.1016/j.matdes.2015.07.051
  9. Yamagata W, Fujisawa T, Sasaki T, et al. Evaluation of the mechanical properties of current biliary self-expandable metallic stents: axial and radial force, and axial force zero border. Clin Endosc 2023;56:633–649. https://doi.org/10.5946/ce.2022.201
  10. Li G, Li Y, Lan P, et al. Study of heat-setting treatment for biomedical polydioxanone stents. J Ind Text 2016;46:75–87. https://doi.org/10.1177/1528083715576317
  11. Lin M, Firoozi N, Tsai CT, et al. 3D-printed flexible polymer stents for potential applications in inoperable esophageal malignancies. Acta Biomater 2019;83:119–129. https://doi.org/10.1016/j.actbio.2018.10.035
  12. Isayama H, Nakai Y, Hamada T, et al. Development of an ideal self-expandable metallic stent design. Gastrointest Interv 2015;4:46–49. https://doi.org/10.1016/j.gii.2015.03.002
  13. Kim JH, Kang TJ, Yu WR. Mechanical modeling of self-expandable stent fabricated using braiding technology. J Biomech 2008;41:3202–3212. https://doi.org/10.1016/j.jbiomech.2008.08.005
  14. Yang K, Ling C, Yuan T, et al. Polymeric biodegradable stent insertion in the esophagus. Polymers (Basel) 2016;8:158. https://doi.org/10.3390/polym8050158
  15. Mbah N, Philips P, Voor MJ, et al. Optimal radial force and size for palliation in gastroesophageal adenocarcinoma: a comparative analysis of current stent technology. Surg Endosc 2017;31:5076–5082. https://doi.org/10.1007/s00464-017-5571-4
  16. Isayama H, Nakai Y, Toyokawa Y, et al. Measurement of radial and axial forces of biliary self-expandable metallic stents. Gastrointest Endosc 2009;70:37–44. https://doi.org/10.1016/j.gie.2008.09.032
  17. Li G, Li Y, Lan P, et al. Biodegradable weft-knitted intestinal stents: fabrication and physical changes investigation in vitro degradation. J Biomed Mater Res A 2014;102:982–990. https://doi.org/10.1002/jbm.a.34759
  18. Uesato M, Akutsu Y, Murakami K, et al. Comparison of efficacy of self-expandable metallic stent placement in the unresectable esophageal cancer patients. Gastroenterol Res Pract 2017;2017:2560510. https://doi.org/10.1155/2017/2560510
  19. Ishioka M, Yoshio T, Sasaki T, et al. Safety and efficacy of self-expandable metallic stent placement using low radial force stent for malignant dysphagia after radiotherapy. Digestion 2022;103:261–268. https://doi.org/10.1159/000522007
  20. Yu P, Huang S, Yang Z, et al. Biomechanical properties of a customizable TPU/PCL blended esophageal stent fabricated by 3D printing. Mater Today Commun 2023;34:105196. https://doi.org/10.1016/j.mtcomm.2022.105196
  21. Zou Q, Xue W, Lin J, et al. Mechanical characteristics of novel polyester/NiTi wires braided composite stent for the medical application. Results Phys 2016;6:440–446. https://doi.org/10.1016/j.rinp.2016.07.007
  22. Algowhary M, Abdelmegid MA. Longitudinal stent elongation or shortening after deployment in the coronary arteries: which is dominant? Egypt Heart J 2021;73:46. https://doi.org/10.1186/s43044-021-00170-9
  23. Baron TH. A practical guide for choosing an expandable metal stent for GI malignancies: is a stent by any other name still a stent? Gastrointest Endosc 2001;54:269–272. https://doi.org/10.1067/mge.2001.116626
  24. du Mesnil de Rochemont R, Yan B, Zanella FE, et al. Conformability of balloon-expandable stents to the carotid siphon: an in vitro study. AJNR Am J Neuroradiol 2006;27:324–326.
  25. Larson B, Adler DG. Lumen-apposing metal stents for gastrointestinal luminal strictures: current use and future directions. Ann Gastroenterol 2019;32:141–146. https://doi.org/10.20524/aog.2019.0337