The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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High vegetable consumption and regular exercise are associated with better quality of life in patients with gout

  • Hyunsue Do (Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine) ;
  • Hyo Jin Choi (Division of Rheumatology, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine) ;
  • Byoongyong Choi (Division of Rheumatology, Department of Internal Medicine, Seoul Medical Center) ;
  • Chang-Nam Son (Division of Rheumatology, Department of Internal Medicine, Eulji University School of Medicine) ;
  • Sang-Hyon Kim (Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine) ;
  • You-Jung Ha (Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital) ;
  • Ji Hyoun Kim (Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital) ;
  • Min Jung Kim (Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center) ;
  • Kichul Shin (Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center) ;
  • Hyun-Ok Kim (Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine) ;
  • Ran Song (Division of Rheumatology, Department of Internal Medicine, Kyung Hee University) ;
  • Sung Won Lee (Division of Rheumatology, Department of Internal Medicine, Soon Chun Hyang University Hospital) ;
  • Joong Kyong Ahn (Division of Rheumatology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine,) ;
  • Seung-Geun Lee (Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital) ;
  • Chang Hoon Lee (Division of Rheumatology, Department of Internal Medicine, Wonkwang University School of Medicine) ;
  • Kyeong Min Son (Division of Rheumatology, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital) ;
  • Ki Won Moon (Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine)
  • Received : 2023.11.04
  • Accepted : 2024.02.05
  • Published : 2024.09.01
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Abstract

Background/Aims: The Gout Impact Scale (GIS), a part of the Gout Assessment Questionnaire 2.0, is used to measure gout-specific health-related quality of life (HRQOL). Although several studies have been conducted on the factors affecting the HRQOL of patients with gout, few have focused on lifestyle factors. This study aimed to investigate the correlation between lifestyle habits and HRQOL using the GIS in patients with gout. Methods: We used data from the Urate-Lowering TheRApy in Gout (ULTRA) registry, a prospective cohort of Korean patients with gout treated at multiple centers nationwide. The patients were aged ≥18 years and met the 2015 American College of Rheumatology/European League Against Rheumatism gout classification criteria. They were asked to complete a GIS and questions regarding their lifestyle habits at enrollment. Results: The study included 232 patients. 'Gout concern overall' scores in the GIS were significantly lower in patients who exercised more frequently and consumed soft drinks and meat less, and 'well-being during attack' scores were significantly lower in patients who consumed vegetables and exercised more frequently. The frequency of vegetable consumption had a negative linear relationship with the 'well-being during attack' and 'gout concern during attack' scores (p = 0.01, p = 0.001, respectively). The frequency of exercise had a negative linear relationship with the 'gout concern overall' and 'gout concern during attack' scores (p = 0.04 and p = 0.002, respectively). Conclusions: Patients with gout who frequently consumed vegetables and exercised regularly experienced less impact of gout, exhibiting a better GIS that represented HRQOL.

Keywords

Acknowledgement

This research was supported by a grant from the Patient-Centered Clinical Research Coordinating Center funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HC21C0010) and a 2023 Kangwon National University Hospital Grant (no. KNUH_2023-05-006).

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