Allergy, Asthma & Respiratory Disease

  • 제12권2호
  • /
  • Pages.85-92
  • /
  • 2024
  • /
  • 2288-0402(pISSN)
  • /
  • 2288-0410(eISSN)
대한천식알레르기학회 (The Korean Academy of Asthma, Allergy and Clinical Immunology)
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부산지역 접촉성피부염 의심 환자에서 첩포검사 결과 분석

Analysis of patch test results in patients with suspected contact dermatitis in the Busan area

  • 김광석 (고신대학교 의과대학) ;
  • 박찬선 (인제대학교 해운대백병원 내과) ;
  • 오지현 (고신대학교 의과대학 내과) ;
  • 김희규 (고신대학교 의과대학 내과) ;
  • 최길순 (고신대학교 의과대학 내과)
  • Gwangseok Kim (Kosin University College of Medicine) ;
  • Chan Sun Park (Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine) ;
  • Ji Hyun Oh (Department of Internal Medicine, Kosin University Gospel Hospital, Kosin University College of Medicine) ;
  • Hee-Kyoo Kim (Department of Internal Medicine, Kosin University Gospel Hospital, Kosin University College of Medicine) ;
  • Gil-Soon Choi (Department of Internal Medicine, Kosin University Gospel Hospital, Kosin University College of Medicine)
  • 투고 : 2023.12.16
  • 심사 : 2024.03.13
  • 발행 : 2024.04.30
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초록

Purpose: Contact dermatitis (CD) is a common skin disease caused by various allergens that can be identified by patch test (PT). Despite the analysis of PT outcomes in various regions of Korea, no specific investigation has targeted the Busan area. We aimed to analyze PT results using Chemotechnique in patients suspected of CD in Busan. Methods: We reviewed medical records of 273 patients who underwent PT between 2019 and 2020 at two university hospitals in Busan. PT results were interpreted according to the International Contact Dermatitis Research Group criteria. Results: Among the patients, 86.4% exhibited positive reactions to at least one allergen. Those with positive outcomes displayed a higher comorbidity rate of chronic urticaria but a lower rate of atopic dermatitis. Moreover, they reported higher positivity rates to questions about sexual life and treatment on the Dermatology Life Quality Index questionnaire. Major allergens in Busan were cobalt chloride (60.1%), nickel sulfate (52.0%), and potassium dichromate (50.9%), followed by thiomersal, balsam of Peru, and fragrance mix (17.2%, 15.4%, and 13.9%, respectively). Captan, budesonide, and colophony were more prevalent allergens in males. While the positive rate for thiomersal were higher in the younger age group, balsam of Peru allergen was higher in the older age group. Conclusion: This study represents the first PT analysis conducted in Busan, revealing metal-related allergen as the most common cause of CD, with variations observed across sex and age. Further research is needed to validate these findings and elucidate the sources and pathways of allergen exposure in Busan.

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참고문헌

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